Home Indole and Oxindoles 13618-91-2
13618-91-2,MFCD00012134
Catalog No.:AA009BB2

13618-91-2 | 4,5,6,7-Tetrahydro-1h-indole

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250mg
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA009BB2
Chemical Name:
4,5,6,7-Tetrahydro-1h-indole
CAS Number:
13618-91-2
Molecular Formula:
C8H11N
Molecular Weight:
121.1796
MDL Number:
MFCD00012134
SMILES:
C1CCc2c(C1)[nH]cc2
NSC Number:
122455
Properties
Computed Properties
 
Complexity:
101  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Donor Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.9  

Downstream Synthesis Route

[1]Tarasova;Brandsma;Trofimov[Synthesis,1993,#6,p.571-572]

[2]Tarasova,O.A.;Mikhaleva,A.I.;Markova,T.L.;Trofimov,B.A.[ChemistryofHeterocyclicCompounds,1992,vol.28,#1,p.108][KhimiyaGeterotsiklicheskikhSoedinenii,1992,#1,p.125]

[1]Trofimov,B.A.;Sobenina,L.N.;Mikhaleva,A.I.[ChemistryofHeterocyclicCompounds,1991,vol.27,#7,p.801][KhimiyaGeterotsiklicheskikhSoedinenii,1991,#7,p.996-997]

[2]Korobchenko;Vladyko;Boreko;Sobenina;Mikhaleva;Sergeeva;Trofimov[PharmaceuticalChemistryJournal,1993,vol.26,#11-12,p.861-864]

[3]Sobenina,L.N.;Protasova,L.E.;Sergeeva,M.P.;Petrova,O.V.;Aksamentova,T.N.;etal.[ChemistryofHeterocyclicCompounds,1995,vol.31,#1,p.40-46][KhimiyaGeterotsiklicheskikhSoedinenii,1995,#1,p.47-54]

[4]Petrova,OlgaV.;Sagitova,ElenaF.;Ushakov,IgorA.;Sobenina,LyubovN.;Mikhaleva,Al'BinaI.;Trofimov,BorisA.[JournalofSulfurChemistry,2015,vol.36,#2,p.145-154]

[5]Petrova,OlgaV.;Sagitova,ElenaF.;Sobenina,LyubovN.;Ushakov,IgorA.;Borodina,Tat′yanaN.;Smirnov,VladimirI.;Trofimov,BorisA.[TetrahedronLetters,2016,vol.57,#32,p.3652-3656]

[6]Alwasel,Saleh;Farzaliyev,Vagif;Gülçin,İlhami;Gusarova,Nina;Kaya,Ruya;Malysheva,Svetlana;Petrova,Olga;Schmidt,Elena;Sobenina,Lyubov;Sujayev,Afsun;Supuran,ClaudiuT.;Taslimi,Parham;Trofimov,Boris[BioorganicChemistry,2020,vol.103]

[1]Tarasova;Brandsma;Trofimov[Synthesis,1993,#6,p.571-572]

[2]Tarasova,O.A.;Trofimov,B.A.;Mikhaleva,A.I.;Sigalov,M.V.;Sinegovskaya,L.M.[JournalofOrganicChemistryUSSR(EnglishTranslation),1991,vol.27,#8,p.1579-1580][ZhurnalOrganicheskoiKhimii,1991,vol.27,#8,p.1798-1799]

[3]Martynovskaya,SvetlanaV.;Shcherbakova,VictoriaS.;Ushakov,IgorA.;Borodina,TatyanaN.;Ivanov,AndreyV.[TetrahedronLetters,2020,vol.61,#52]

[1]Ryashentseva,M.A.[RussianChemicalBulletin,1993,vol.42,#10,p.1756-1757][IzvestiyaAkademiiNaukSSSR,SeriyaKhimicheskaya,1993,#10,p.1832-1833]

[2]Ryashentseva,M.A.[RussianChemicalBulletin,1993,vol.42,#10,p.1756-1757][IzvestiyaAkademiiNaukSSSR,SeriyaKhimicheskaya,1993,#10,p.1832-1833]

[3]Ryashentseva[ChemistryofHeterocyclicCompounds,2006,vol.42,#8,p.1018-1020]

[4]Locationinpatent:experimentalpartTrofimov;Mikhaleva;Vasil'Tsov;Ivanov;Schmidt,E.Yu.;Protsuk;Ryapolov[DokladyChemistry,2010,vol.434,#2,p.257-259]

[5]Locationinpatent:experimentalpartTrofimov;Mikhaleva;Schmidt;Protsuk;Ivanov;Ryapolov[DokladyChemistry,2011,vol.437,#2,p.95-97]

[6]Berg,E.M.M.vanden;Jansen,F.J.H.M.;Goede,A.T.J.W.de;Baldew,A.U.;Lugtenburg,J.[RecueildesTravauxChimiquesdesPays-Bas,1990,vol.109,#4,p.287-297]

[7]Berg,E.M.M.vanden;Jansen,F.J.H.M.;Goede,A.T.J.W.de;Baldew,A.U.;Lugtenburg,J.[RecueildesTravauxChimiquesdesPays-Bas,1990,vol.109,#4,p.287-297]

[1]Berg,E.M.M.vanden;Jansen,F.J.H.M.;Goede,A.T.J.W.de;Baldew,A.U.;Lugtenburg,J.[RecueildesTravauxChimiquesdesPays-Bas,1990,vol.109,#4,p.287-297]

[2]Berg,E.M.M.vanden;Jansen,F.J.H.M.;Goede,A.T.J.W.de;Baldew,A.U.;Lugtenburg,J.[RecueildesTravauxChimiquesdesPays-Bas,1990,vol.109,#4,p.287-297]

Literature

Title: Design and synthesis of potent hydroxyethylamine (HEA) BACE-1 inhibitors carrying prime side 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templates.

Journal: Bioorganic & medicinal chemistry letters 20121101

Title: Direct functionalization of (un)protected tetrahydroisoquinoline and isochroman under iron and copper catalysis: two metals, two mechanisms.

Journal: The Journal of organic chemistry 20111104

Title: Maintenance of immune hyporesponsiveness to melanosomal proteins by DHICA-mediated antioxidation: Possible implications for autoimmune vitiligo.

Journal: Free radical biology & medicine 20110501

Title: Synthesis, cellular uptake and animal toxicity of a tetra(carboranylphenyl)-tetrabenzoporphyrin.

Journal: Bioorganic & medicinal chemistry 20060315

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Tags:13618-91-2 Molecular Formula|13618-91-2 MDL|13618-91-2 SMILES|13618-91-2 4,5,6,7-Tetrahydro-1h-indole |Heterocyclic_Building_Blocks