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136676-91-0,MFCD11046022
Catalog No.:AA00124C

136676-91-0 | PD123319 Ditrifluoroacetate

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5mg
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10mg
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$250.00   $175.00
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25mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00124C
Chemical Name:
PD123319 Ditrifluoroacetate
CAS Number:
136676-91-0
Molecular Formula:
C35H34F6N4O7
Molecular Weight:
736.6575
MDL Number:
MFCD11046022
SMILES:
OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)[C@@H]1Cc2c(CN1C(=O)C(c1ccccc1)c1ccccc1)ncn2Cc1ccc(c(c1)C)N(C)C
Properties
Computed Properties
 
Complexity:
874  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
52  
Hydrogen Bond Acceptor Count:
15  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
7  

Literature

Title: Angiotensin AT2 receptor stimulation inhibits activation of NADPH oxidase and ameliorates oxidative stress in rotenone model of Parkinson's disease in CATH.a cells.

Journal: Neurotoxicology and teratology 20150101

Title: Similarities and differences between effects of angiotensin III and angiotensin II on human prostate cancer cell migration and proliferation.

Journal: Peptides 20121001

Title: Cardiovascular actions of angiotensin-(1-12) in the hypothalamic paraventricular nucleus of the rat are mediated via angiotensin II.

Journal: Experimental physiology 20120901

Title: Perinatal nicotine exposure increases vulnerability of hypoxic-ischemic brain injury in neonatal rats: role of angiotensin II receptors.

Journal: Stroke 20120901

Title: Angiotensin II type 2 receptor-mediated inhibition of NaCl absorption is blunted in thick ascending limbs from Dahl salt-sensitive rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20120901

Title: Compound 21 induces vasorelaxation via an endothelium- and angiotensin II type 2 receptor-independent mechanism.

Journal: Hypertension (Dallas, Tex. : 1979) 20120901

Title: Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells.

Journal: Regulatory peptides 20120820

Title: Resveratrol attenuates angiotensin II-induced senescence of vascular smooth muscle cells.

Journal: Regulatory peptides 20120820

Title: Angiotensin-(3-4) counteracts the Angiotensin II inhibitory action on renal Ca2+-ATPase through a cAMP/PKA pathway.

Journal: Regulatory peptides 20120820

Title: Presence and physiologic function of the renin-angiotensin system in mouse lacrimal gland.

Journal: Investigative ophthalmology & visual science 20120813

Title: Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors.

Journal: Hypertension (Dallas, Tex. : 1979) 20120801

Title: Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells.

Journal: Canadian journal of physiology and pharmacology 20120801

Title: Role of central angiotensin receptors in scopolamine-induced impairment in memory, cerebral blood flow, and cholinergic function.

Journal: Psychopharmacology 20120701

Title: AT2 receptor non-peptide agonist C21 promotes natriuresis in obese Zucker rats.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120601

Title: Angiotensin II induces tumor necrosis factor-α expression and release from cultured human podocytes.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120401

Title: From the first selective non-peptide AT(2) receptor agonist to structurally related antagonists.

Journal: Journal of medicinal chemistry 20120308

Title: HIV-associated nephropathy: role of AT2R.

Journal: Cellular signalling 20120301

Title: Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor.

Journal: Hypertension (Dallas, Tex. : 1979) 20120201

Title: Mechanisms of dopamine D(1) and angiotensin type 2 receptor interaction in natriuresis.

Journal: Hypertension (Dallas, Tex. : 1979) 20120201

Title: Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory.

Journal: Neurobiology of learning and memory 20120101

Title: The roles of angiotensin II receptors in the portosystemic collaterals of portal hypertensive and cirrhotic rats.

Journal: Journal of vascular research 20120101

Title: The involvement of angiotensin type 1 and type 2 receptors in estrogen-induced cell proliferation and vascular endothelial growth factor expression in the rat anterior pituitary.

Journal: TheScientificWorldJournal 20120101

Title: Angiotensin II type 1 receptor, but no type 2 receptor, interferes with the insulin-induced nitric oxide production in HUVECs.

Journal: Atherosclerosis 20111201

Title: Effects of captopril and angiotensin II receptor blockers (AT1, AT2) on myocardial ischemia-reperfusion induced infarct size.

Journal: Cytokine 20111201

Title: Cardioplegia and angiotensin II receptor antagonists modulate signal transducers and activators of transcription activation in neonatal rat myocytes.

Journal: Artificial organs 20111101

Title: Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors.

Journal: Clinical science (London, England : 1979) 20111001

Title: Angiotensin III stimulates ERK1/2 mitogen-activated protein kinases and astrocyte growth in cultured rat astrocytes.

Journal: Neuropeptides 20111001

Title: Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures.

Journal: Journal of neurochemistry 20111001

Title: Intracellular angiotensin II activates rat myometrium.

Journal: American journal of physiology. Cell physiology 20110901

Title: Both AT₁ and AT₂ receptors mediate proliferation and migration of porcine vascular smooth muscle cells.

Journal: American journal of physiology. Heart and circulatory physiology 20110901

Title: Activation of central angiotensin type 2 receptors suppresses norepinephrine excretion and blood pressure in conscious rats.

Journal: American journal of hypertension 20110601

Title: 20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II and endothelin-1.

Journal: American journal of physiology. Heart and circulatory physiology 20110401

Title: A single beta-amino acid substitution to angiotensin II confers AT2 receptor selectivity and vascular function.

Journal: Hypertension (Dallas, Tex. : 1979) 20110301

Title: Endogenous angiotensin II suppresses stretch-induced ANP secretion via AT1 receptor pathway.

Journal: Peptides 20110201

Title: Blockade of the renin-angiotensin system ameliorates apelin production in 3T3-L1 adipocytes.

Journal: Cardiovascular drugs and therapy 20110201

Title: Angiotensin AT₂ receptor stimulation inhibits early renal inflammation in renovascular hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20110201

Title: Co-operative effects of angiotensin II and caerulein in NFκB activation in pancreatic acinar cells in vitro.

Journal: Regulatory peptides 20110117

Title: Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea.

Journal: Brain research 20110112

Title: Involvement of the AT1 receptor in the venoconstriction induced by angiotensin II in both the inferior vena cava and femoral vein.

Journal: Peptides 20110101

Title: Mechanisms related to NO-induced motility in differentiated rat aortic smooth muscle cells.

Journal: American journal of physiology. Heart and circulatory physiology 20110101

Title: Cardiovascular responses elicited by a new endogenous angiotensin in the nucleus tractus solitarius of the rat.

Journal: American journal of physiology. Heart and circulatory physiology 20110101

Title: Lack of heterologous receptor desensitization induced by angiotensin II type 1 receptor activation in isolated normal rat thoracic aorta.

Journal: Vascular pharmacology 20110101

Title: The effect of the expression of angiotensin II on extracellular matrix metalloproteinase inducer (EMMPRIN) in macrophages is mediated via the AT1/COX-2/PGE2 pathway.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20101201

Title: Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2).

Journal: Cellular signalling 20101201

Title: p63RhoGEF--a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201

Title: AT₁ receptor and NAD(P)H oxidase mediate angiotensin II-stimulated antioxidant enzymes and mitogen-activated protein kinase activity in the rat hypothalamus.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20101201

Title: Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cδ.

Journal: Clinical and experimental pharmacology & physiology 20101201

Title: Deficiency or blockade of angiotensin II type 2 receptor delays tumorigenesis by inhibiting malignant cell proliferation and angiogenesis.

Journal: International journal of cancer 20101115

Title: Location of prorenin receptors in primate substantia nigra: effects on dopaminergic cell death.

Journal: Journal of neuropathology and experimental neurology 20101101

Title: Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway.

Journal: Journal of cellular physiology 20101001

Title: Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20101001

Title: Angiotensin II enhances connecting tubule glomerular feedback.

Journal: Hypertension (Dallas, Tex. : 1979) 20101001

Title: [Regeneration of perivascular nerve and role of angiotensin receptors].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100901

Title: Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100801

Title: Neuroprotection against retinal ischemia-reperfusion injury by blocking the angiotensin II type 1 receptor.

Journal: Investigative ophthalmology & visual science 20100701

Title: The renin-angiotensin system mediates hyperoxia-induced collagen production in human lung fibroblasts.

Journal: Free radical biology & medicine 20100701

Title: Multiple cross talk between angiotensin II, bradykinin, and insulin signaling in the cortical thick ascending limb of rat kidney.

Journal: Endocrinology 20100701

Title: Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition.

Journal: Bioorganic & medicinal chemistry 20100615

Title: Expressions of inducible nitric oxide synthase and cyclooxygenase-2 in gastric ischemia-reperfusion: role of angiotensin II.

Journal: The Journal of surgical research 20100601

Title: Direct angiotensin II type 2 receptor stimulation decreases dopamine synthesis in the rat striatum.

Journal: Neuropharmacology 20100601

Title: Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation.

Journal: Basic research in cardiology 20100501

Title: Angiotensin II-activated protein kinase D mediates acute aldosterone secretion.

Journal: Molecular and cellular endocrinology 20100412

Title: Developmental effect of antenatal exposure to betamethasone on renal angiotensin II activity in the young adult sheep.

Journal: American journal of physiology. Renal physiology 20100401

Title: Effect of acute stress on sexual behavior in female rats: participation of the central angiotensinergic system.

Journal: Behavioural brain research 20100305

Title: Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis.

Journal: American journal of physiology. Renal physiology 20100301

Title: Angiotensin II exerts glucose-dependent effects on Kv currents in mouse pancreatic beta-cells via angiotensin II type 2 receptors.

Journal: American journal of physiology. Cell physiology 20100201

Title: Inhibitory effects of angiotensin-(1-7) on the nerve stimulation-induced release of norepinephrine and neuropeptide Y from the mesenteric arterial bed.

Journal: American journal of physiology. Heart and circulatory physiology 20100201

Title: Angiotensin II type 1 and type 2 receptors regulate basal skeletal muscle microvascular volume and glucose use.

Journal: Hypertension (Dallas, Tex. : 1979) 20100201

Title: Intrarenal aminopeptidase N inhibition restores defective angiontesin II type 2-mediated natriuresis in spontaneously hypertensive rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20100201

Title: Effects of angiotensin metabolites in the coronary vascular bed of the spontaneously hypertensive rat: loss of angiotensin II type 2 receptor-mediated vasodilation.

Journal: Hypertension (Dallas, Tex. : 1979) 20100201

Title: Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats.

Journal: British journal of pharmacology 20100201

Title: Angiotensin II activates JAK2/STAT3 pathway and induces interleukin-6 production in cultured rat brainstem astrocytes.

Journal: Regulatory peptides 20100108

Title: Angiotensin II signaling via type 2 receptors in a human model of vascular hyporeactivity: implications for hypertension.

Journal: Journal of hypertension 20100101

Title: Molecular mechanisms of the antagonistic action between AT1 and AT2 receptors.

Journal: Biochemical and biophysical research communications 20100101

Title: Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus.

Journal: Hypertension (Dallas, Tex. : 1979) 20100101

Title: [The effect of angiotensin II on phosphoinositide-3 kinase/Akt cascade in cultured fibroblasts derived from patients with hypertrophic scars].

Journal: Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery 20100101

Title: Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage.

Journal: Journal of hypertension 20091201

Title: Prenatal blockade of Ang II receptors affects neonatal rat hindbrain structure and receptor localization.

Journal: Experimental neurology 20091201

Title: Contribution of epidermal growth factor receptor transactivation in angiotensin II-induced enhanced expression of Gi protein and proliferation in A10 vascular smooth muscle cells.

Journal: Canadian journal of physiology and pharmacology 20091201

Title: Angiotensin II receptors are expressed and functional in human esophageal mucosa.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20091101

Title: Angiotensin II effects on ischemic focal ventricular tachycardia are predominantly mediated through myocardial AT(2) receptor.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: Angiotensin II receptor blockade improves matrix metalloproteinases/tissue inhibitor of matrix metalloproteinase-1 balance and restores fibronectin expression in rat infarcted myocardium.

Journal: Biochemical and biophysical research communications 20091023

Title: The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy.

Journal: Endocrinology 20090901

Title: Acute modulation of myocardial function by angiotensin 1-7.

Journal: Peptides 20090901

Title: Guanylyl cyclase-A inhibits angiotensin II type 2 receptor-mediated pro-hypertrophic signaling in the heart.

Journal: Endocrinology 20090801

Title: Angiotensin II type-2 (AT2) receptor antagonism alters cardiovascular responses to static exercise and simultaneously changes glutamate/GABA levels within the ventrolateral medulla.

Journal: Neuroscience research 20090801

Title: Conditional expression of type 2 angiotensin II receptor in rat vascular smooth muscle cells reveals the interplay of the angiotensin system in matrix metalloproteinase 2 expression and vascular remodeling.

Journal: International journal of molecular medicine 20090701

Title: [Role of angiotensin II and JAK2 signal pathway in transdifferentation of renal tubular cells in mice after acute ischemic followed by reperfusion].

Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20090701

Title: Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats.

Journal: American journal of physiology. Heart and circulatory physiology 20090301

Title: Regulation of T-cell function by endogenously produced angiotensin II.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090201

Title: Intrarenal angiotensin III infusion induces natriuresis and angiotensin type 2 receptor translocation in Wistar-Kyoto but not in spontaneously hypertensive rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20090201

Title: Angiotensin II type 1 receptor-mediated reduction of angiotensin-converting enzyme 2 activity in the brain impairs baroreflex function in hypertensive mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20090201

Title: A peripherally administered, centrally acting angiotensin II AT2 antagonist selectively increases brain AT1 receptors and decreases brain tyrosine hydroxylase transcription, pituitary vasopressin and ACTH.

Journal: Brain research 20090123

Title: Angiotensin II-mediated vasodilation is reduced in adult spontaneously hypertensive rats despite enhanced expression of AT2 receptors.

Journal: Clinical and experimental pharmacology & physiology 20090101

Title: Role of angiotensin II in the response to endothelin-1 of goat cerebral arteries after ischemia-reperfusion.

Journal: Vascular pharmacology 20090101

Title: Role of angiotensin II type 1 receptor on retinal vascular leakage in a rat oxygen-induced retinopathy model.

Journal: Ophthalmic research 20090101

Title: Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease.

Journal: BMC cardiovascular disorders 20090101

Title: The influence of peptides from the angiotensin family on tyrosine kinase activity and cell viability in a human hormone-dependent prostate cancer line.

Journal: Endokrynologia Polska 20090101

Title: Regulation of renal 12(S)-hydroxyeicosatetraenoic acid in diabetes by angiotensin AT1 and AT2 receptors.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20081101

Title: Nerve stimulation induced overflow of neuropeptide Y and modulation by angiotensin II in spontaneously hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology 20081101

Title: Imbalance of angiotensin type 1 receptor and angiotensin II type 2 receptor in the rostral ventrolateral medulla: potential mechanism for sympathetic overactivity in heart failure.

Journal: Hypertension (Dallas, Tex. : 1979) 20081001

Title: Human brain contains a novel non-AT1, non-AT2 binding site for active angiotensin peptides.

Journal: Life sciences 20080912

Title: Angiotensin IV-evoked vasoprotection is conserved in advanced atheroma.

Journal: Atherosclerosis 20080901

Title: Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts.

Journal: Journal of cardiovascular pharmacology 20080801

Title: Estrogen elicits dorsal root ganglion axon sprouting via a renin-angiotensin system.

Journal: Endocrinology 20080701

Title: Upregulation of AT2 receptor and iNOS impairs angiotensin II-induced contraction without endothelium influence in young normotensive diabetic rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080701

Title: Intradermal angiotensin II administration attenuates the local cutaneous vasodilator heating response.

Journal: American journal of physiology. Heart and circulatory physiology 20080701

Title: Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide.

Journal: Hypertension (Dallas, Tex. : 1979) 20080701

Title: Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney.

Journal: European journal of pharmacology 20080624

Title: Angiotensin (1-7) reduces intraocular pressure in the normotensive rabbit eye.

Journal: Investigative ophthalmology & visual science 20080601

Title: Angiotensin II upregulates LDL receptor-related protein (LRP1) expression in the vascular wall: a new pro-atherogenic mechanism of hypertension.

Journal: Cardiovascular research 20080601

Title: Angiotensin II type 2 receptor stimulation increases the rate of NG108-15 cell migration via actin depolymerization.

Journal: Endocrinology 20080601

Title: Angiotensin II receptor blocker inhibits tumour necrosis factor-alpha-induced cell damage in human renal proximal tubular epithelial cells.

Journal: Nephrology (Carlton, Vic.) 20080601

Title: Contractility of placental vascular smooth muscle cells in response to stimuli produced by the placenta: roles of ACE vs. non-ACE and AT1 vs. AT2 in placental vessel cells.

Journal: Placenta 20080601

Title: Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity.

Journal: Experimental physiology 20080501

Title: Prenatal gender-related nicotine exposure increases blood pressure response to angiotensin II in adult offspring.

Journal: Hypertension (Dallas, Tex. : 1979) 20080401

Title: Molecular mechanism of ADP-ribosyl cyclase activation in angiotensin II signaling in murine mesangial cells.

Journal: American journal of physiology. Renal physiology 20080401

Title: Coronary constriction to angiotensin II is enhanced by endothelial superoxide production in sheep programmed by dexamethasone.

Journal: Pediatric research 20080401

Title: Analysis of the vasorelaxant action of angiotensin II in the isolated rat renal artery.

Journal: Journal of pharmacological sciences 20080301

Title: Angiotensin II type 1 receptor antagonist improves the prognosis in rats displaying liver cirrhosis induced by a choline-deficient diet.

Journal: Journal of gastrointestinal and liver diseases : JGLD 20080301

Title: Role of the renin angiotensin system in TNF-alpha and Shiga-toxin-induced tissue factor expression.

Journal: Pediatric nephrology (Berlin, Germany) 20080201

Title: Role of bradykinin, nitric oxide, and angiotensin II type 2 receptor in imidapril-induced angiogenesis.

Journal: Hypertension (Dallas, Tex. : 1979) 20080201

Title: Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20080201

Title: Angiotensin II type 2 receptors and nitric oxide sustain oxygenation in the clipped kidney of early Goldblatt hypertensive rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20080201

Title: Evidence for functional expression of vascular angiotensin II type 2 receptors in patients with insulin resistance.

Journal: Diabetes, obesity & metabolism 20080201

Title: Negative inotropic effect of selective AT2 receptor stimulation and its modulation by the endocardial endothelium.

Journal: European journal of pharmacology 20080114

Title: Angiotensin II induces vascular endothelial growth factor in pancreatic cancer cells through an angiotensin II type 1 receptor and ERK1/2 signaling.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20080101

Title: Improvement of stunned myocardium in dogs with olmesartan, an angiotensin II type 1 receptor antagonist, is independent of type 2 receptors.

Journal: Pharmacology 20080101

Title: Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice.

Journal: Respiratory research 20080101

Title: Distribution of the non-AT1, non-AT2 angiotensin-binding site in the rat brain: preliminary characterization.

Journal: Neuroendocrinology 20080101

Title: Angiotensin II type 2 receptors facilitate reinnervation of phenol-lesioned vascular calcitonin gene-related peptide-containing nerves in rat mesenteric arteries.

Journal: Neuroscience 20071212

Title: Angiotensin II protects against alpha-synuclein toxicity and reduces protein aggregation in vitro.

Journal: Biochemical and biophysical research communications 20071123

Title: Angiotensin II receptors subtypes mediate diverse gene expression profile in adult hypertrophic cardiomyocytes.

Journal: Clinical and experimental pharmacology & physiology 20071101

Title: Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway.

Journal: Hypertension (Dallas, Tex. : 1979) 20071101

Title: The effect of angiotensin II and IV on ERK1/2 and CREB signalling in cultured rat astroglial cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20071101

Title: The role of angiotensin II in the early stages of bovine ovulation.

Journal: Reproduction (Cambridge, England) 20071101

Title: [The influence of angiotensin II receptor blockade on the expressions of Col I and TIMP-1 mRNA in cardiac fibroblast of adult rat].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20071101

Title: Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20071001

Title: Angiotensin-(1-7) inhibits in vitro endothelial cell tube formation in human umbilical vein endothelial cells through the AT(1-7) receptor.

Journal: Endocrine 20071001

Title: Angiotensin II type 2 receptor vasoactivity in internal mammary arteries of patients with coronary artery disease.

Journal: Journal of cardiovascular pharmacology 20071001

Title: [Association between murine double minute 2 expression and AngII and ceramide induced endothelial cells apoptosis].

Journal: Zhonghua xin xue guan bing za zhi 20071001

Title: Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway.

Journal: Investigative ophthalmology & visual science 20070901

Title: Expression of the local angiotensin II system in gastric cancer may facilitate lymphatic invasion and nodal spread.

Journal: Cancer biology & therapy 20070801

Title: Importance of intracellular angiotensin II in vascular smooth muscle cell apoptosis: inhibition by the angiotensin AT1 receptor antagonist irbesartan.

Journal: European journal of pharmacology 20070719

Title: 17beta-estradiol inhibits angiotensin II-induced collagen synthesis of cultured rat cardiac fibroblasts via modulating angiotensin II receptors.

Journal: European journal of pharmacology 20070719

Title: Angiotensin-(1-7) blocks the angiotensin II-stimulated superoxide production.

Journal: Pharmacological research 20070701

Title: [Signal transductional mechanism of calpain involved in the regulation of rat hypertrophy myocardium mediated by overloaded pressure].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070701

Title: Angiotensin II increases expression and secretion of cathepsin F in cultured human monocyte-derived macrophages: an angiotensin II type 2 receptor-mediated effect.

Journal: Atherosclerosis 20070601

Title: Angiotensin II mediates postischemic leukocyte-endothelial interactions: role of calcitonin gene-related peptide.

Journal: American journal of physiology. Heart and circulatory physiology 20070601

Title: On the mechanism of coronary vasodilation induced by angiotensin-(1-7) in the isolated guinea pig heart.

Journal: Basic & clinical pharmacology & toxicology 20070601

Title: Angiotensin II-induced genomic damage in renal cells can be prevented by angiotensin II type 1 receptor blockage or radical scavenging.

Journal: American journal of physiology. Renal physiology 20070501

Title: Induction of monocyte chemoattractant protein-1 expression by angiotensin II in the pancreatic islets and beta-cells.

Journal: Endocrinology 20070501

Title: Identification of a novel non-AT1, non-AT2 angiotensin binding site in the rat brain.

Journal: Brain research 20070427

Title: Angiotensin II type 2 receptor decreases ischemia reperfusion induced fluid leak.

Journal: The Journal of surgical research 20070401

Title: Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1.

Journal: Molecular endocrinology (Baltimore, Md.) 20070201

Title: Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor.

Journal: American journal of physiology. Heart and circulatory physiology 20070201

Title: The role of angiotensin II in stress urinary incontinence: A rat model.

Journal: Neurourology and urodynamics 20070101

Title: Intrarenal dopamine D1-like receptor stimulation induces natriuresis via an angiotensin type-2 receptor mechanism.

Journal: Hypertension (Dallas, Tex. : 1979) 20070101

Title: [Alteration of signal transduction-associated gene expression in rat cardiac fibroblasts induced by blocking angiotensin II receptors].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20061225

Title: Translocation of AT1- and AT2-receptors by higher concentrations of angiotensin II in the smooth muscle cells of rat internal anal sphincter.

Journal: The Journal of pharmacology and experimental therapeutics 20061201

Title: Local renin angiotensin expression regulates human mesenchymal stem cell differentiation to adipocytes.

Journal: Hypertension (Dallas, Tex. : 1979) 20061201

Title: Regulation of cGMP synthesis in cultured podocytes by vasoactive hormones.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201

Title: Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships.

Journal: Journal of medicinal chemistry 20061130

Title: Angiotensin II regulates migration in mouse cultured mesangial cells: evidence for the presence of receptor subtype-specific regulation.

Journal: The Journal of endocrinology 20061101

Title: Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20061001

Title: Ang II and Ang III modulate PTZ seizure threshold in non-stressed and stressed mice: possible involvement of noradrenergic mechanism.

Journal: Neuropeptides 20061001

Title: Biphasic actions of angiotensin IV on renal blood flow in the rat.

Journal: Regulatory peptides 20060911

Title: Effects of i.c.v. losartan on the angiotensin II-mediated vasopressin release and hypothalamic fos expression in near-term ovine fetuses.

Journal: Peptides 20060901

Title: Angiotensin type 1 and type 2 receptor blockade in chronic allograft nephropathy.

Journal: Kidney international 20060901

Title: Angiotensin II induced contraction of rat and human small intestinal wall musculature in vitro.

Journal: Acta physiologica (Oxford, England) 20060901

Title: AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases.

Journal: American journal of physiology. Renal physiology 20060801

Title: Angiotensin II disrupts inhibitory avoidance memory retrieval.

Journal: Hormones and behavior 20060801

Title: Angiotensin II type 2 receptor agonist directly inhibits proximal tubule sodium pump activity in obese but not in lean Zucker rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20060601

Title: AT2 receptor-mediated vasodilation in the mouse heart depends on AT1A receptor activation.

Journal: British journal of pharmacology 20060601

Title: Dual mechanisms of angiotensin-induced activation of mouse sympathetic neurones.

Journal: The Journal of physiology 20060515

Title: The AT1A receptor 'gain-of-function' mutant N111S/delta329 is both constitutively active and hyperreactive to angiotensin II.

Journal: American journal of physiology. Endocrinology and metabolism 20060501

Title: Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance.

Journal: Metabolism: clinical and experimental 20060401

Title: Renal angiotensin type 2 receptors mediate natriuresis via angiotensin III in the angiotensin II type 1 receptor-blocked rat.

Journal: Hypertension (Dallas, Tex. : 1979) 20060301

Title: Angiotensin II-induced vasodilatation in cerebral arteries is mediated by endothelium-derived hyperpolarising factor.

Journal: European journal of pharmacology 20060215

Title: Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes.

Journal: American journal of physiology. Cell physiology 20060201

Title: Renal angiotensin II AT2 receptors promote natriuresis in streptozotocin-induced diabetic rats.

Journal: American journal of physiology. Renal physiology 20060201

Title: Direct regulation of insulin secretion by angiotensin II in human islets of Langerhans.

Journal: Diabetologia 20060201

Title: Role of angiotensin II receptor subtypes in porcine basilar artery: functional, radioligand binding, and cell culture studies.

Journal: Life sciences 20060125

Title: Opposing actions of angiotensin II type 1 and 2 receptors on plasma cholesterol levels in rats.

Journal: Journal of hypertension 20060101

Title: Transactivation of the epidermal growth factor receptor by angiotensin II in glomerular podocytes.

Journal: Nephron. Experimental nephrology 20060101

Title: Angiotensin II regulates extraneuronal dopamine uptake in the kidney.

Journal: Nephron. Physiology 20060101

Title: Constrictor and dilator effects of angiotensin II on cerebral arterioles.

Journal: Stroke 20051201

Title: Reversal of fructose-induced hypertension and insulin resistance by chronic losartan treatment is independent of AT2 receptor activation in rats.

Journal: Journal of hypertension 20051201

Title: Neuroprotective effects of candesartan against cerebral ischemia in spontaneously hypertensive rats.

Journal: Neuroreport 20051128

Title: Nitric oxide contributes to AT2 but not AT1 angiotensin II receptor-mediated vasodilatation of porcine pial arteries and arterioles.

Journal: European journal of pharmacology 20051121

Title: Biphasic effects of angiotensin II and receptor antagonism on aggregability and protein kinase C phosphorylation in human platelets.

Journal: Thrombosis and haemostasis 20051101

Title: NADPH oxidase-derived superoxide anion mediates angiotensin II-induced pressor effect via activation of p38 mitogen-activated protein kinase in the rostral ventrolateral medulla.

Journal: Circulation research 20051014

Title: Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart.

Journal: Hypertension (Dallas, Tex. : 1979) 20051001

Title: Deletion of angiotensin II type 2 receptor exaggerated atherosclerosis in apolipoprotein E-null mice.

Journal: Circulation 20050913

Title: Coexpression of AT1 and AT2 receptors by human fibroblasts is associated with resistance to angiotensin II.

Journal: Peptides 20050901

Title: ANG II increases 2-deoxyglucose uptake in mouse embryonic stem cells.

Journal: Life sciences 20050826

Title: The effect of angiotensin III on protein tyrosine kinase activity in rat pituitary.

Journal: Regulatory peptides 20050815

Title: Angiotensin II and interleukin-1 interact to increase generation of dopaminergic neurons from neurospheres of mesencephalic precursors.

Journal: Brain research. Developmental brain research 20050808

Title: Angiotensin II induced increase in frequency of cytosolic and nuclear calcium waves of heart cells via activation of AT1 and AT2 receptors.

Journal: Peptides 20050801

Title: Tubular expression of angiotensin II receptors and their regulation in IgA nephropathy.

Journal: Journal of the American Society of Nephrology : JASN 20050801

Title: Electrophysiological properties of rostral ventrolateral medulla neurons in angiotensin II 1a receptor knockout mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20050801

Title: Does the AT2-receptor mediate anti-atherosclerotic actions?

Journal: Journal of hypertension 20050801

Title: Angiotensin II infusion increases hepatic triglyceride production via its type 2 receptor in rats.

Journal: Journal of hypertension 20050801

Title: Angiotensin II, type 2 receptor is not involved in the angiotensin II-mediated pro-atherogenic process in ApoE-/- mice.

Journal: Journal of hypertension 20050801

Title: Blockade of endogenous angiotensin-(1-7) in the hypothalamic paraventricular nucleus reduces renal sympathetic tone.

Journal: Hypertension (Dallas, Tex. : 1979) 20050801

Title: In vivo characterization of the angiotensin-(1-7)-induced dopamine and gamma-aminobutyric acid release in the striatum of the rat.

Journal: The European journal of neuroscience 20050801

Title: Angiotensin II increases human monocyte matrix metalloproteinase-1 through the AT2 receptor and prostaglandin E2: implications for atherosclerotic plaque rupture.

Journal: Journal of leukocyte biology 20050701

Title: Angiotensin II blocks memory consolidation through an AT2 receptor-dependent mechanism.

Journal: Psychopharmacology 20050501

Title: AT2 receptors contribute to acute blood pressure-lowering and vasodilator effects of AT1 receptor antagonism in conscious normotensive but not hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology 20050501

Title: Angiotensin-(1-7) acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20050501

Title: Candesartan prevents angiotensin II-induced facilitation of hypoxic neuronal damage through PKCdelta inhibition.

Journal: Brain research. Molecular brain research 20050427

Title: Protein kinase C-mediated inhibition of renal Ca2+ ATPase by physiological concentrations of angiotensin II is reversed by AT1- and AT2-receptor antagonists.

Journal: Regulatory peptides 20050415

Title: Central angiotensin II AT1 receptors mediate fetal swallowing and pressor responses in the near-term ovine fetus.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050401

Title: Angiotensin II receptor inhibition prevents pneumocyte apoptosis in surfactant-depleted rat lungs.

Journal: Pediatric pulmonology 20050401

Title: NAD(P)H oxidase inhibition attenuates neuronal chronotropic actions of angiotensin II.

Journal: Circulation research 20050401

Title: Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance.

Journal: Diabetes 20050401

Title: The expression of messenger RNA for ADP-ribosyl cyclase in aldosterone-producing adenomas.

Journal: Clinical endocrinology 20050401

Title: Diminution of angiotensin II-induced contraction of the abdominal aorta isolated from Watanabe heritable hyperlipidemic rabbits.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20050401

Title: Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20050201

Title: AT(2) receptors mediate tonic renal medullary vasoconstriction in renovascular hypertension.

Journal: British journal of pharmacology 20050201

Title: Angiotensin II-dependent induction of AT(2) receptor expression after renal ablation.

Journal: American journal of physiology. Renal physiology 20050101

Title: Angiotensin II receptor modulation of renal vascular resistance and neurotransmission in young and adult spontaneously hypertensive rats.

Journal: Kidney & blood pressure research 20050101

Title: Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation.

Journal: Hypertension (Dallas, Tex. : 1979) 20050101

Title: Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: role of the renin-angiotensin system.

Journal: Journal of hypertension 20050101

Title: Reactive oxygen species-mediated signaling pathways in angiotensin II-induced MCP-1 expression of proximal tubular cells.

Journal: Antioxidants & redox signaling 20050101

Title: ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kappaB activity and AT1 receptor expression.

Journal: Biochemical and biophysical research communications 20041210

Title: Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II.

Journal: Circulation research 20041210

Title: Angiotensin II stimulates Pax-2 in rat kidney proximal tubular cells: impact on proliferation and apoptosis.

Journal: Kidney international 20041201

Title: Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells.

Journal: The Journal of endocrinology 20041201

Title: Angiotensin II stimulates arachidonic acid release from bone marrow stromal cells.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20041201

Title: Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist.

Journal: Journal of medicinal chemistry 20041118

Title: Angiotensin AT2 receptor contributes to cardiovascular remodelling of aged rats during chronic AT1 receptor blockade.

Journal: Journal of molecular and cellular cardiology 20041101

Title: Angiotensin II-induced relaxation of anococcygeus smooth muscle via desensitization of AT1 receptor, and activation of AT2 receptor associated with nitric-oxide synthase pathway.

Journal: The Journal of pharmacology and experimental therapeutics 20041001

Title: A pharmacological differentiation between postjunctional (AT1A) and prejunctional (AT1B) angiotensin II receptors in the rabbit aorta.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20041001

Title: Angiotensin II attenuates NMDA receptor-mediated neuronal cell death and prevents the associated reduction in Bcl-2 expression.

Journal: Brain research. Molecular brain research 20040910

Title: Metabolism of angiotensin II is required for its in vivo effect on dopamine release in the striatum of the rat.

Journal: Journal of neurochemistry 20040901

Title: Effect of angiotensin II type 1 receptor on delayed rectifier potassium current in catecholaminergic CATH.a cells.

Journal: Acta pharmacologica Sinica 20040901

Title: Angiotensin II increases differentiation of dopaminergic neurons from mesencephalic precursors via angiotensin type 2 receptors.

Journal: The European journal of neuroscience 20040901

Title: Angiotensin II and angiotensin-(1-7) inhibit the inner cortex Na+ -ATPase activity through AT2 receptor.

Journal: Regulatory peptides 20040815

Title: The role of the pancreatic renin-angiotensin system in acinar digestive enzyme secretion and in acute pancreatitis.

Journal: Regulatory peptides 20040715

Title: Angiotensin II stimulates the release of interleukin-6 and interleukin-8 from cultured human adipocytes by activation of NF-kappaB.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20040701

Title: Altered effects of angiotensin ii type 1 and type 2 receptor blockers on cardiac norepinephrine release and inotropic responses during cardiac sympathetic nerve stimulation in aorto-caval shunt rats.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20040701

Title: AT2 receptor and apoptosis during AT1 receptor blockade in reperfused myocardial infarction in the rat.

Journal: Molecular and cellular biochemistry 20040701

Title: Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors.

Journal: Circulation research 20040625

Title: Chronic production of angiotensin IV in the brain leads to hypertension that is reversible with an angiotensin II AT1 receptor antagonist.

Journal: Circulation research 20040611

Title: Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding.

Journal: Hypertension (Dallas, Tex. : 1979) 20040601

Title: Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor.

Journal: Journal of the American Society of Nephrology : JASN 20040601

Title: Effects of angiotensin II type 1 receptor antagonist on pressor responses to pulsatile compression of the rostral ventrolateral medulla in rats.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20040601

Title: Angiotensin II type 2 receptor-mediated vasodilation in human coronary microarteries.

Journal: Circulation 20040518

Title: Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors.

Journal: Hypertension (Dallas, Tex. : 1979) 20040501

Title: Angiotensin type-1 receptor blockade increases ACE 2 expression in the heart.

Journal: Hypertension (Dallas, Tex. : 1979) 20040501

Title: Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20040501

Title: Tonic angiotensinergic inputs to neurons in the anterior hypothalamic area of rats.

Journal: Brain research 20040501

Title: Angiotensin-(1-7) inhibits the angiotensin II-enhanced norepinephrine release in coarcted hypertensive rats.

Journal: Regulatory peptides 20040415

Title: First reported nonpeptide AT1 receptor agonist (L-162,313) acts as an AT2 receptor agonist in vivo.

Journal: Journal of medicinal chemistry 20040311

Title: Regulation of inhibitory protein-kappaB and monocyte chemoattractant protein-1 by angiotensin II type 2 receptor-activated Src homology protein tyrosine phosphatase-1 in fetal vascular smooth muscle cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20040301

Title: Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040301

Title: Dietary salt intake modulates progression of antithymocyte serum nephritis through alteration of glomerular angiotensin II receptor expression.

Journal: American journal of physiology. Renal physiology 20040201

Title: Prophylactic and therapeutic treatments with AT 1 and AT 2 receptor antagonists and their effects on changes in the severity of pancreatitis.

Journal: The international journal of biochemistry & cell biology 20040201

Title: Retinal expression of vascular endothelial growth factor is mediated by angiotensin type 1 and type 2 receptors.

Journal: Hypertension (Dallas, Tex. : 1979) 20040201

Title: Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets.

Journal: Diabetologia 20040201

Title: Different AT1 receptor subtypes at pre- and postjunctional sites: AT1A versus AT1B receptors.

Journal: Journal of cardiovascular pharmacology 20040101

Title: Tubular and interstitial cell apoptosis in the streptozotocin-diabetic rat kidney.

Journal: Nephron. Experimental nephrology 20040101

Title: Increase in systemic blood pressure during intra-arterial PD123319 infusion: evidence for functional expression of angiotensin type 2 receptors in normal volunteers.

Journal: Blood pressure 20040101

Title: Importance of the angiotensin type 1 receptor in angiotensin II-induced bronchoconstriction and bronchial hyperresponsiveness in the guinea pig.

Journal: Experimental lung research 20040101

Title: Angiotensin II mediates Tyr-dephosphorylation in rat fetal kidney membranes.

Journal: Molecular and cellular biochemistry 20031201

Title: Evidence for a functional role of angiotensin II type 2 receptor in the cardiac hypertrophic process in vivo in the rat heart.

Journal: Circulation 20031111

Title: Responses to GABA-A receptor blockade in the hypothalamic PVN are attenuated by local AT1 receptor antagonism.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20031101

Title: Effects of angiotensin II on nitric oxide generation in growing and resting rat aortic endothelial cells.

Journal: Journal of hypertension 20031101

Title: Angiotensin II type 2 receptor inhibits prorenin processing in juxtaglomerular cells.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20031101

Title: Angiotensin AT2 receptors directly stimulate renal nitric oxide in bradykinin B2-receptor-null mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20031001

Title: Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis.

Journal: Circulation 20030923

Title: Angiotensin II type 2 receptor inhibits vascular endothelial growth factor-induced migration and in vitro tube formation of human endothelial cells.

Journal: Circulation research 20030905

Title: Patients with steroid refractory acute vascular rejection develop agonistic antibodies targeting angiotensin II type 1 receptor.

Journal: Transplantation proceedings 20030901

Title: Effects of angiotensin II on nitric oxide generation in proliferating and quiescent rat coronary microvascular endothelial cells.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030901

Title: Disparate roles of AT2 receptors in the renal cortical and medullary circulations of anesthetized rabbits.

Journal: Hypertension (Dallas, Tex. : 1979) 20030801

Title: Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.

Journal: British journal of pharmacology 20030801

Title: Angiotensin II and III microinjections into the zona incerta influence drinking behavior.

Journal: Brain research 20030711

Title: Effects of ANG II type 1 and 2 receptors on oxidative stress, renal NADPH oxidase, and SOD expression.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030701

Title: Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615

Title: Effect of angiotensin AT2 receptor stimulation on vascular cyclic GMP production in normotensive Wistar Kyoto rats.

Journal: The international journal of biochemistry & cell biology 20030601

Title: An AT1-receptor antagonist and an angiotensin-converting enzyme inhibitor protect against hypoxia-induced apoptosis in human aortic endothelial cells through upregulation of endothelial cell nitric oxide synthase activity.

Journal: Shock (Augusta, Ga.) 20030601

Title: No involvement of the AT2-receptor in angiotensin II-enhanced sympathetic transmission in vitro.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20030601

Title: Biphasic effects of angiotensin (1-7) and its interactions with angiotensin II in rat aorta.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20030601

Title: Angiotensin II AT(1) and AT(2) receptors contribute to maintain basal adrenomedullary norepinephrine synthesis and tyrosine hydroxylase transcription.

Journal: Endocrinology 20030501

Title: Localization of AT(2) receptors in the nucleus of the solitary tract of spontaneously hypertensive and Wistar Kyoto rats using [125I] CGP42112: upregulation of a non-angiotensin II binding site following unilateral nodose ganglionectomy.

Journal: Brain research 20030404

Title: Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20030401

Title: Influence of angiotensin II receptor subtypes of the paraventricular nucleus on the physiological responses induced by angiotensin II injection into the medial septal area.

Journal: Arquivos brasileiros de cardiologia 20030401

Title: Angiotensin II-induced release of oxytocin: interaction with norepinephrine and role in lactation.

Journal: Regulatory peptides 20030328

Title: The effects of sarmesin, an Angiotensin II analogue on seizure susceptibility, memory retention and nociception.

Journal: Regulatory peptides 20030328

Title: ANG II AT2 receptor modulates AT1 receptor-mediated descending vasa recta endothelial Ca2+ signaling.

Journal: American journal of physiology. Heart and circulatory physiology 20030301

Title: Role of the angiotensin II system in regulation of ovulation and blood flow in the rat ovary.

Journal: Reproduction (Cambridge, England) 20030301

Title: Cardiac myofibroblasts: a novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR.

Journal: Journal of molecular and cellular cardiology 20030301

Title: Divergent roles of angiotensin II AT1 and AT2 receptors in modulating coronary microvascular function.

Journal: Circulation research 20030221

Title: Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030101

Title: Angiotensin II type 2 receptor blockade partially negates antihypertrophic effects of type 1 receptor blockade on pressure-overload rat cardiac hypertrophy.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030101

Title: Effect of neutral endopeptidase inhibition on vascular response induced by exogenous angiotensin I in the isolated rat lung.

Journal: Polish journal of pharmacology 20030101

Title: Prejunctional AT(1) receptor subtype-dependent modification of neurotransmitter releases in canine isolated splenic arteries.

Journal: Autonomic & autacoid pharmacology 20030101

Title: Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis.

Journal: Circulation research 20021213

Title: Biphasic regulation of Na+-HCO3- cotransporter by angiotensin II type 1A receptor.

Journal: Hypertension (Dallas, Tex. : 1979) 20021101

Title: Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).

Journal: Hypertension (Dallas, Tex. : 1979) 20021101

Title: Dose-dependent regulation of NAD(P)H oxidase expression by angiotensin II in human endothelial cells: protective effect of angiotensin II type 1 receptor blockade in patients with coronary artery disease.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20021101

Title: Cross-talk between AT(1) and AT(2) angiotensin receptors in rat anococcygeus smooth muscle.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Interaction between paraventricular nucleus and septal area in the control of physiological responses induced by angiotensin II.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020901

Title: Effect of intranasal administration of CV-11974, a type 1 angiotensin II receptor antagonist, on airway hyperresponsiveness and airway inflammation induced by antigen inhalation in guinea pigs.

Journal: International archives of allergy and immunology 20020901

Title: Involvement of the AT(2)-receptor in angiotensin II-induced facilitation of sympathetic neurotransmission.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20020901

Title: Effects of AT1 and AT2 receptor blockade on angiotensin II induced apoptosis of human renal proximal tubular epithelial cells.

Journal: Wiener klinische Wochenschrift 20020830

Title: Angiotensin actions on the isolated rat uterus during the estrous cycle: influence of resting membrane potential and uterine morphology.

Journal: Pharmacology 20020701

Title: Angiotensin II induces apoptosis in rat glomerular epithelial cells.

Journal: American journal of physiology. Renal physiology 20020701

Title: Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury.

Journal: Journal of the American Society of Nephrology : JASN 20020701

Title: Aldosterone breakthrough during angiotensin II receptor antagonist therapy in stroke-prone spontaneously hypertensive rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20020701

Title: Differences in AT2 -receptor stimulation between AT1 -receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP.

Journal: Journal of hypertension 20020601

Title: Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor- and inflammation-related pathways.

Journal: Laboratory investigation; a journal of technical methods and pathology 20020601

Title: 125I[Sar(1)Ile(8)] angiotensin II has a different affinity for AT(1) and AT(2) receptor subtypes in ovine tissues.

Journal: Regulatory peptides 20020515

Title: Role of angiotensin II and angiotensin II receptors in vascular smooth muscle cell migration in vitro.

Journal: Chinese medical journal 20020501

Title: AT(2) but not AT(1) receptor antagonism abolishes angiotensin II increase of the acquisition of conditioned avoidance responses in rats.

Journal: Behavioural brain research 20020401

Title: Angiotensin receptor subtype AT(1) mediates alveolar epithelial cell apoptosis in response to ANG II.

Journal: American journal of physiology. Lung cellular and molecular physiology 20020401

Title: Influence of estrogen and/or progesterone on isolated ovariectomized rat uterus. Responsiveness to Ang II.

Journal: Pharmacology 20020401

Title: Angiotensin protects cortical neurons from hypoxic-induced apoptosis via the angiotensin type 2 receptor.

Journal: Brain research. Molecular brain research 20020328

Title: Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles.

Journal: Life sciences 20020322

Title: Vasodilator action of angiotensin-(1-7) on isolated rabbit afferent arterioles.

Journal: Hypertension (Dallas, Tex. : 1979) 20020301

Title: Forearm vasodilator response to angiotensin II in elderly women receiving candesartan: role of AT(2)- receptors.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20020301

Title: Angiotensin II stimulates migration of retinal microvascular pericytes: involvement of TGF-beta and PDGF-BB.

Journal: American journal of physiology. Heart and circulatory physiology 20020201

Title: The mechanism of angiotensin II binding downregulation by high glucose in primary renal proximal tubule cells.

Journal: American journal of physiology. Renal physiology 20020201

Title: Angiotensin II directly stimulates macula densa Na-2Cl-K cotransport via apical AT(1) receptors.

Journal: American journal of physiology. Renal physiology 20020201

Title: Dilatation of cerebral parenchymal vessels mediated by angiotensin type 1 receptor in cats.

Journal: Neuroscience letters 20020125

Title: Angiotensin-(1-7) reverts the stimulatory effect of angiotensin II on the proximal tubule Na(+)-ATPase activity via a A779-sensitive receptor.

Journal: Regulatory peptides 20020115

Title: Chronic hypotensive effects of losartan are not dependent on the actions of angiotensin II at AT 2 receptors.

Journal: Journal of cardiovascular pharmacology 20020101

Title: Angiotensin peptides modulate bradykinin levels in the interstitium of the dog heart in vivo.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Differential effect of angiotensin II on blood circulation in the renal medulla and cortex of anaesthetised rats.

Journal: The Journal of physiology 20020101

Title: Vasoconstriction is determined by interstitial rather than circulating angiotensin II.

Journal: British journal of pharmacology 20020101

Title: Angiotensin II type 2 receptor counter-regulates type 1 receptor in catecholamine synthesis in cultured porcine adrenal medullary chromaffin cells.

Journal: Hypertension (Dallas, Tex. : 1979) 20020101

Title: Angiotensin II in cardiac pressure-overload hypertrophy in fetal sheep.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011201

Title: AT(2) receptor-mediated vasodilation in the heart: effect of myocardial infarction.

Journal: American journal of physiology. Heart and circulatory physiology 20011201

Title: Regulation of vascular proteoglycan synthesis by angiotensin II type 1 and type 2 receptors.

Journal: Journal of the American Society of Nephrology : JASN 20011201

Title: Intracellular angiotensin II inhibits heterologous receptor stimulated Ca2+ entry.

Journal: Life sciences 20011130

Title: Angiotensin subtype-2 receptor (AT2 ) negatively regulates subtype-1 receptor (AT1 ) in signal transduction pathways in cultured porcine adrenal medullary chromaffin cells.

Journal: Journal of hypertension 20011101

Title: Autoradiographic determination of angiotensin II receptors in prepubertal and postpubertal pig ovarian tissue.

Journal: Reproduction (Cambridge, England) 20011101

Title: Corpuscles of Stannius secrete renin or an isorenin that regulates cardiovascular function in freshwater North American eels, Anguilla rostrata LeSueur.

Journal: General and comparative endocrinology 20011101

Title: Blockade of angiotensin receptor subtypes in arcuate uterine artery of pregnant and postpartum rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20011101

Title: Identification and characterization of functional angiotensin II type 1 receptors on immortalized human fetal aortic vascular smooth muscle cells.

Journal: Molecular and cellular endocrinology 20011025

Title: Increased AT(1) receptors in adrenal gland of AT(2) receptor gene-disrupted mice.

Journal: Regulatory peptides 20011015

Title: Angiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells.

Journal: Circulation 20011009

Title: Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia.

Journal: The Journal of endocrinology 20011001

Title: Role of AT1 and AT2 receptor subtypes in salt-sensitive hypertension induced by sensory nerve degeneration.

Journal: Journal of hypertension 20011001

Title: Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis.

Journal: British journal of pharmacology 20011001

Title: Angiotensin II type 2 receptor inhibits epidermal growth factor receptor transactivation by increasing association of SHP-1 tyrosine phosphatase.

Journal: Hypertension (Dallas, Tex. : 1979) 20010901

Title: Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.

Journal: Hypertension (Dallas, Tex. : 1979) 20010901

Title: No effect of angiotensin II AT(2)-receptor antagonist PD 123319 on cerebral blood flow autoregulation.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20010901

Title: Identification of angiotensin II type 2 (AT2) receptor domains mediating high-affinity CGP 42112A binding and receptor activation.

Journal: The Journal of pharmacology and experimental therapeutics 20010801

Title: Angiotensin II AT(2) receptors inhibit growth responses in proximal tubule cells.

Journal: American journal of physiology. Renal physiology 20010801

Title: Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation.

Journal: Journal of neurochemistry 20010801

Title: Angiotensin-converting enzyme inhibition potentiates angiotensin II type 1 receptor effects on renal bradykinin and cGMP.

Journal: Hypertension (Dallas, Tex. : 1979) 20010801

Title: Combined angiotensin converting enzyme inhibition and angiotensin AT(1) receptor blockade up-regulates myocardial AT(2) receptors in remodeled myocardium post-infarction.

Journal: Cardiovascular research 20010701

Title: Activation of angiotensin II subtype 2 receptor induces catecholamine release in an extracellular Ca(2+)-dependent manner through a decrease of cyclic guanosine 3',5'-monophosphate production in cultured porcine adrenal medullary chromaffin Cells.

Journal: Endocrinology 20010701

Title: Effect of angiotensin II on calcium reabsorption by the luminal membranes of the nephron.

Journal: American journal of physiology. Endocrinology and metabolism 20010601

Title: Endogenous angiotensin II in the NTS contributes to sympathetic activation in rats with aortocaval shunt.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010601

Title: Coronary hemodynamic and ventricular responses to angiotensin type 1 receptor inhibition in SHR: interaction with angiotensin type 2 receptors.

Journal: Hypertension (Dallas, Tex. : 1979) 20010601

Title: Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20010601

Title: Intracellular angiotensin II elicits Ca2+ increases in A7r5 vascular smooth muscle cells.

Journal: European journal of pharmacology 20010518

Title: Angiotensin II AT1 receptors preserve vasodilator reactivity in skeletal muscle resistance arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20010501

Title: Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors.

Journal: The American journal of pathology 20010501

Title: Chronotropic effect of angiotensin II via type 2 receptors in rat brain neurons.

Journal: Journal of neurophysiology 20010501

Title: Angiotensin II type I receptor modulates intracellular free Mg2+ in renally derived cells via Na+-dependent Ca2+-independent mechanisms.

Journal: The Journal of biological chemistry 20010427

Title: Atypical angiotensin receptors may mediate water intake induced by central injections of angiotensin II and of serotonin in pigeons.

Journal: Regulatory peptides 20010420

Title: Angiotensin receptor in the heart of Bothrops jararaca snake.

Journal: European journal of pharmacology 20010406

Title: Tonic suppression of spontaneous baroreceptor reflex by endogenous angiotensins via AT(2) subtype receptors at nucleus reticularis ventrolateralis in the rat.

Journal: Synapse (New York, N.Y.) 20010401

Title: Mechanisms of angiotensin-(1-7)-induced inhibition of angiogenesis.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010401

Title: Brain angiotensin receptors and sympathoadrenal regulation during insulin-induced hypoglycemia.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010401

Title: Intracellular Angiotensin II and cell growth of vascular smooth muscle cells.

Journal: British journal of pharmacology 20010401

Title: At receptor inhibition affects the noradrenaline sensitivity in isolated portal vein of normotensive rat.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20010401

Title: Mechanism of the cardioprotective effect of inhibition of the renin-angiotensin system on ischemia/reperfusion-induced myocardial injury.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20010301

Title: Hyperoxia/normoxia-driven retinal angiogenesis in mice: a role for angiotensin II.

Journal: Investigative ophthalmology & visual science 20010201

Title: Transcriptional and translational regulation of calpain in the rat heart after myocardial infarction--effects of AT(1) and AT(2) receptor antagonists and ACE inhibitor.

Journal: British journal of pharmacology 20010201

Title: Angiotensin II relaxes microvessels via the AT(2) receptor and Ca(2+)-activated K(+) (BK(Ca)) channels.

Journal: Hypertension (Dallas, Tex. : 1979) 20010201

Title: p38 Map kinase regulates vascular smooth muscle cell collagen synthesis by angiotensin II in SHR but not in WKY.

Journal: Hypertension (Dallas, Tex. : 1979) 20010201

Title: Regulation of K+ transport in the rat distal colon via angiotensin II subtype receptors and K+ -pathways.

Journal: Acta physiologica Scandinavica 20010201

Title: Central AT1 and AT2 receptors mediate chronic intracerebroventricular angiotensin II-induced drinking in rats fed high sodium chloride diet from weaning.

Journal: Acta physiologica Scandinavica 20010201

Title: Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation.

Journal: Circulation research 20010119

Title: Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN).

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010101

Title: Increased AT(1) receptor expression and mRNA in kidney glomeruli of AT(2) receptor gene-disrupted mice.

Journal: American journal of physiology. Renal physiology 20010101

Title: Functional expression of angiotensin II receptors in type-I cells of the rat carotid body.

Journal: Pflugers Archiv : European journal of physiology 20010101

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