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137-66-6,MFCD00005377
Catalog No.:AA00HUPE

137-66-6 | Ascorbyl palmitate

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250mg
95%
in stock  
$6.00   $4.00
- +
25g
95%
in stock  
$21.00   $15.00
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100g
95%
in stock  
$39.00   $28.00
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500g
95%
in stock  
$110.00   $77.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00HUPE
Chemical Name:
Ascorbyl palmitate
CAS Number:
137-66-6
Molecular Formula:
C22H38O7
Molecular Weight:
414.5329
MDL Number:
MFCD00005377
SMILES:
CCCCCCCCCCCCCCCC(=O)OC[C@@H]([C@H]1OC(=O)C(=C1O)O)O
Properties
Computed Properties
 
Complexity:
515  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
18  
XLogP3:
6.3  

Literature

Title: Evaluation of the antioxidative capability of commonly used antioxidants in dermocosmetics by in vivo detection of protein carbonylation in human stratum corneum.

Journal: Journal of photochemistry and photobiology. B, Biology 20120702

Title: PA and fish oil.

Journal: British dental journal 20120427

Title: Radical-regulating and antiviral properties of ascorbic acid and its derivatives.

Journal: Bioorganic & medicinal chemistry letters 20120401

Title: Palmitoyl ascorbate liposomes and free ascorbic acid: comparison of anticancer therapeutic effects upon parenteral administration.

Journal: Pharmaceutical research 20120201

Title: The ascorbyl palmitate-polyethyleneglycol 400-water system phase behavior.

Journal: Colloids and surfaces. B, Biointerfaces 20120101

Title: Effect of antioxidants on oxidation during the production of whey fat concentrate.

Journal: Journal of agricultural and food chemistry 20111228

Title: Lipid-soluble vitamin C palmitate and protection of human high-density lipoprotein from hypochlorite-mediated oxidation.

Journal: International journal of cardiology 20111020

Title: Antibacterial electrospun poly(ɛ-caprolactone)/ascorbyl palmitate nanofibrous materials.

Journal: International journal of pharmaceutics 20110915

Title: Vitamin C derivatives as new coreactants for tris(2,2'-bipyridine)ruthenium(II) electrochemiluminescence.

Journal: Analytica chimica acta 20110909

Title: Surface phase behavior and domain topography of ascorbyl palmitate monolayers.

Journal: Langmuir : the ACS journal of surfaces and colloids 20110906

Title: Enzymatic synthesis of ascorbyl palmitate in ultrasound-assisted system: process optimization and kinetic evaluation.

Journal: Ultrasonics sonochemistry 20110901

Title: Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase.

Journal: European journal of medicinal chemistry 20110901

Title: Lipid-like sulfoxides and amine oxides as inhibitors of mast cell activation.

Journal: European journal of medicinal chemistry 20110601

Title: Chemical stabilization of oils rich in long-chain polyunsaturated fatty acids during storage.

Journal: Food science and technology international = Ciencia y tecnologia de los alimentos internacional 20110401

Title: Biodistribution of ascorbyl palmitate loaded doxorubicin pegylated liposomes in solid tumor bearing mice.

Journal: Journal of microencapsulation 20110101

Title: SRMS142-based solid lipid microparticles: application in oral delivery of glibenclamide to diabetic rats.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20100901

Title: A new approach for increasing ascorbyl palmitate stability by addition of non-irritant co-antioxidant.

Journal: AAPS PharmSciTech 20100901

Title: Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation.

Journal: Journal of microencapsulation 20100501

Title: Encapsulation of ascorbyl palmitate in chitosan nanoparticles by oil-in-water emulsion and ionic gelation processes.

Journal: Colloids and surfaces. B, Biointerfaces 20100301

Title: Enrichment of foods with omega-3 fatty acids: a multidisciplinary challenge.

Journal: Annals of the New York Academy of Sciences 20100301

Title: Determination of tocopheryl acetate and ascorbyl tetraisopalmitate in cosmetic formulations by HPLC.

Journal: International journal of cosmetic science 20091201

Title: Ascorbic acid 6-palmitate suppresses gap-junctional intercellular communication through phosphorylation of connexin 43 via activation of the MEK-ERK pathway.

Journal: Mutation research 20090115

Title: Pursuit of oxidation behavior for conjugated polyenoyl glycerols and establishment of their novel oxidation prevention method.

Journal: Journal of oleo science 20090101

Title: Sterol superlattice affects antioxidant potency and can be used to assess adverse effects of antioxidants.

Journal: Analytical biochemistry 20081101

Title: Coating of peanuts with edible whey protein film containing alpha-tocopherol and ascorbyl palmitate.

Journal: Journal of food science 20081001

Title: Effects of 6-month daily supplementation with oral beta-carotene in combination or not with benzo[a]pyrene on cell-cycle markers in the lung of ferrets.

Journal: The Journal of nutritional biochemistry 20080501

Title: Development of ascorbyl palmitate nanocrystals applying the nanosuspension technology.

Journal: International journal of pharmaceutics 20080416

Title: Modulation of digestive enzyme activities during ontogeny of Labeo rohita larvae fed ascorbic acid enriched zooplankton.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080401

Title: Physicochemical characterization and in vitro release studies of ascorbyl palmitate-loaded semi-solid nanostructured lipid carriers (NLC gels).

Journal: Journal of microencapsulation 20080301

Title: New potent indole derivatives as hyaluronidase inhibitors.

Journal: Chemical biology & drug design 20071201

Title: Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC)--effects of formulation parameters on physicochemical stability.

Journal: International journal of pharmaceutics 20070801

Title: Physical properties of whey protein coating solutions and films containing antioxidants.

Journal: Journal of food science 20070601

Title: Design of novel antifungal mucoadhesive films. Part II. Formulation and in vitro biopharmaceutical evaluation.

Journal: International journal of pharmaceutics 20070524

Title: Ascorbyl palmitate, gamma-tocopherol, and EDTA affect lipid oxidation in fish oil enriched salad dressing differently.

Journal: Journal of agricultural and food chemistry 20070321

Title: Design of novel antifungal mucoadhesive films Part I. Pre-formulation studies.

Journal: International journal of pharmaceutics 20070207

Title: Ultrasound accelerated esterification of palmitic acid with vitamin C.

Journal: Ultrasonics sonochemistry 20070201

Title: Skin permeation enhancement of ascorbyl palmitate by liposomal hydrogel (lipogel) formulation and electrical assistance.

Journal: Biological & pharmaceutical bulletin 20070201

Title: Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases.

Journal: Bioorganic & medicinal chemistry letters 20061015

Title: Production of ascorbyl palmitate by surfactant-coated lipase in organic media.

Journal: Journal of agricultural and food chemistry 20060809

Title: [Biological synthesis of L-ascorbyl palmitate].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20051101

Title: Skin moisturizing effect and skin penetration of ascorbyl palmitate entrapped in solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) incorporated into hydrogel.

Journal: Die Pharmazie 20051001

Title: Stability of ascorbyl palmitate molecule in the rat brain.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050901

Title: Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for application of ascorbyl palmitate.

Journal: Die Pharmazie 20050801

Title: Protection against oxidation of fish-oil-enriched milk emulsions through addition of rapeseed oil or antioxidants.

Journal: Journal of agricultural and food chemistry 20050629

Title: A multicenter, double-blind, safety study of QR-333 for the treatment of symptomatic diabetic peripheral neuropathy. A preliminary report.

Journal: Journal of diabetes and its complications 20050101

Title: Nasal delivery of insulin using chitosan microspheres.

Journal: Journal of microencapsulation 20041101

Title: Apoptosis by 6-O-palmitoyl-L-ascorbic acid coincides with JNK-phosphorylation and inhibition of Mg2+-dependent phosphatase activity.

Journal: Biochemical pharmacology 20040301

Title: Ascorbyl palmitate vesicles (Aspasomes): formation, characterization and applications.

Journal: International journal of pharmaceutics 20040301

Title: Ascorbyl palmitate augments hypoxic respiratory response in the cat.

Journal: Journal of biomedical science 20040101

Title: Capacity of ascorbyl palmitate to produce the ascorbyl radical in vitro: an electron spin resonance investigation.

Journal: Physiological research 20040101

Title: Diverse effects of ascorbic acid and palmitoyl ascorbate on Helicobacter pylori survival and growth.

Journal: FEMS microbiology letters 20030729

Title: Skin protection against ultraviolet induced free radicals with ascorbyl palmitate in microemulsions.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20030701

Title: Effect of colloidal carriers on ascorbyl palmitate stability.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030701

Title: Sodium ascorbyl phosphate in topical microemulsions.

Journal: International journal of pharmaceutics 20030430

Title: Ascorbyl palmitate as a carrier of ascorbate into neural tissues.

Journal: Journal of biomedical science 20030101

Title: Ascorbate in the carotid body.

Journal: Advances in experimental medicine and biology 20030101

Title: Ascorbyl palmitate and its synergism to tocopherols.

Journal: Forum of nutrition 20030101

Title: Antioxidative effects of alpha-tocopherol and ascorbyl palmitate on thermal oxidation of canola oil.

Journal: Die Nahrung 20021201

Title: Michael adducts of palmitoylascorbic acid: effects on the oxidative burst of neutrophils and the production of tumor necrosis factor-alpha in monocytes.

Journal: Pharmacology 20021101

Title: Ascorbyl-6-palmitate is not ascorbic acid.

Journal: The Journal of investigative dermatology 20021101

Title: Vitamin C derivative ascorbyl palmitate promotes ultraviolet-B-induced lipid peroxidation and cytotoxicity in keratinocytes.

Journal: The Journal of investigative dermatology 20021101

Title: Free radical scavenging and skin penetration of troxerutin and vitamin derivatives.

Journal: The Journal of dermatological treatment 20020901

Title: Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo.

Journal: Clinical pharmacology and therapeutics 20020901

Title: Suppressive effect of saturated acyl L-ascorbate on the oxidation of linoleic acid encapsulated with maltodextrin or gum arabic by spray-drying.

Journal: Journal of agricultural and food chemistry 20020703

Title: Evaluation of the surfactant properties of ascorbyl palmitate sodium salt.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020701

Title: Synthesis and characterization of a series of novel monoacylated ascorbic acid derivatives, 6-O-acyl-2-O-alpha-D-glucopyranosyl-L-ascorbic acids, as skin antioxidants.

Journal: Journal of medicinal chemistry 20020117

Title: Effects of alpha lipoic acid, ascorbic acid-6-palmitate, and fish oil on the glutathione, malonaldehyde, and fatty acids levels in erythrocytes of streptozotocin induced diabetic male rats.

Journal: Journal of cellular biochemistry 20020101

Title: Effects of certain micronutrients and melatonin on plasma lipid, lipid peroxidation, and homocysteine levels in rats.

Journal: Archives of medical research 20020101

Title: Determination of ascorbyl 6-palmitate in food matrices by amperometric flow injection analysis.

Journal: The Analyst 20010801

Title: Stability of ascorbyl palmitate in topical microemulsions.

Journal: International journal of pharmaceutics 20010717

Title: H(2)O(2) mediates oxidative stress-induced epidermal growth factor receptor phosphorylation.

Journal: Toxicology letters 20010706

Title: In vitro test for the effectiveness of antioxidants as inhibitors of thiyl radical-induced reactions with unsaturated fatty acids.

Journal: Journal of agricultural and food chemistry 20010301

Title: Antioxidative activity of benzylideneascorbate and its effect on adriamycin-induced cardiotoxicity.

Journal: Anticancer research 19940101

Title: Ascorbic acid and adriamycin toxicity.

Journal: The American journal of clinical nutrition 19911201

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