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Home Other Building Blocks 137201-62-8
137201-62-8,MFCD00671447
Catalog No.:AA0012V0

137201-62-8 | L-Threonine, L-leucyl-L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-

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Purity
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Price(USD)
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1mg
≥95%
in stock  
$173.00   $121.00
- +
5mg
≥95%
in stock  
$479.00   $335.00
- +
10mg
≥95%
in stock  
$765.00   $535.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0012V0
Chemical Name:
L-Threonine, L-leucyl-L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-
CAS Number:
137201-62-8
Molecular Formula:
C45H64N8O10
Molecular Weight:
877.0373
MDL Number:
MFCD00671447
SMILES:
CC(C[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)O)[C@H](O)C)Cc1c[nH]c2c1cccc2)Cc1ccc(cc1)O)C(C)C)C(C)C)N)C
Properties
Computed Properties
 
Complexity:
1590  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
63  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
10  
Rotatable Bond Count:
21  
XLogP3:
1  

Literature

Title: Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist.

Journal: Journal of medicinal chemistry 20070906

Title: Spinorphin as an endogenous inhibitor of enkephalin-degrading enzymes: roles in pain and inflammation.

Journal: Current protein & peptide science 20021201

Title: The endogenous opioid spinorphin blocks fMet-Leu-Phe-induced neutrophil chemotaxis by acting as a specific antagonist at the N-formylpeptide receptor subtype FPR.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20011201

Title: Spinorphin, an endogenous inhibitor of enkephalin-degrading enzymes, potentiates leu-enkephalin-induced anti-allodynic and antinociceptive effects in mice.

Journal: Japanese journal of pharmacology 20011201

Title: Identification of dipeptidyl peptidase III in human neutrophils.

Journal: Biochemical and biophysical research communications 20000705

Title: Inhibitory effects of spinorphin, a novel endogenous regulator, on chemotaxis, O2- generation, and exocytosis by N-formylmethionyl-leucyl-phenylalanine (FMLP)-stimulated neutrophils.

Journal: Biochemical pharmacology 19970915

Title: Reversed-phase high-performance liquid chromatography for the determination of haemorphin-like immunoreactivity in human cerebrospinal fluid.

Journal: Journal of chromatography. A 19940729

Title: A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family.

Journal: The Journal of biological chemistry 19920415

Title: M Honda, et al. Spinorphin, an endogenous inhibitor of enkephalin-degrading enzymes, potentiates leu-enkephalin-induced anti-allodynic and antinociceptive effects in mice. Jpn J Pharmacol. 2001 Dec;87(4):261-7.

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SDS
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Tags:137201-62-8 Molecular Formula|137201-62-8 MDL|137201-62-8 SMILES|137201-62-8 L-Threonine, L-leucyl-L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-