Home Amines 138-14-7
138-14-7,MFCD00058605
Catalog No.:AA007ZB5

138-14-7 | Deferoxamine mesylate

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5mg
≥98%
in stock  
$75.00   $53.00
- +
100mg
95%
in stock  
$78.00   $54.00
- +
250mg
98%
in stock  
$90.00   $63.00
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500mg
≥95%
in stock  
$105.00   $73.00
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1g
≥95%
in stock  
$175.00   $122.00
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5g
95%
in stock  
$643.00   $450.00
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10g
95%
in stock  
$1,192.00   $834.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA007ZB5
Chemical Name:
Deferoxamine mesylate
CAS Number:
138-14-7
Molecular Formula:
C26H52N6O10S
Molecular Weight:
640.7903
MDL Number:
MFCD00058605
SMILES:
CS(=O)(=O)O.NCCCCCNC(=O)CCC(=O)NCCCCCN(C(=O)CCC(=O)NCCCCCN(C(=O)C)O)O
Properties
Computed Properties
 
Complexity:
832  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
7  
Rotatable Bond Count:
23  

Downstream Synthesis Route

[1]Chimiak,Andrzej;Neilands,JohnBrian[ZeitschriftfurChemie,1985,vol.25,#9,p.329-330]

138-14-7   
2,3-dimethoxy-4-(methylcarbamoyl)benzoylchloride 
  153502-62-6 

[1]Hou,Zhiguo;WhisenhuntJr.,DonaldW.;Xu,Jide;Raymond,KennethN.[JournaloftheAmericanChemicalSociety,1994,vol.116,#3,p.840-846]

138-14-7   
N-(2,3-dihydroxy-4-(methylamido)benzoyl)desferrioxamineB 

[1]Hou,Zhiguo;WhisenhuntJr.,DonaldW.;Xu,Jide;Raymond,KennethN.[JournaloftheAmericanChemicalSociety,1994,vol.116,#3,p.840-846]

[1]Lim,Jongdoo;Venditto,VincentJ.;Simanek,EricE.[BioorganicandMedicinalChemistry,2010,vol.18,#15,p.5749-5753]

[2]CurrentPatentAssignee:STATEUNIVERSITYSYSTEMOFFLORIDA-WO2005/23310,2005,A2Locationinpatent:Page/Pagecolumn38;7/16

7440-55-3    138-14-7   
(Ga(III)desferrioxaminBcomplex)mesylate 

[1]Borgias,Brandan;Hugi,AlainD.;Raymond,KennethN.[InorganicChemistry,1989,vol.28,#18,p.3538-3545]

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Journal: Bioorganic & medicinal chemistry 20120615

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Journal: Experimental brain research 20120601

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Journal: Journal of cellular physiology 20111101

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Journal: European journal of pediatrics 20111101

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Journal: Acta biomaterialia 20111101

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Journal: Stroke 20111101

Title: Lethal iron deprivation induced by non-neutralizing antibodies targeting transferrin receptor 1 in malignant B cells.

Journal: Leukemia & lymphoma 20111101

Title: The role of reduction in iron uptake processes in a unicellular, planktonic cyanobacterium.

Journal: Environmental microbiology 20111101

Title: Hand warmer related corrosive injury.

Journal: Clinical toxicology (Philadelphia, Pa.) 20111101

Title: Challenges of adherence and persistence with iron chelation therapy.

Journal: International journal of hematology 20111101

Title: Towards the prevention of potential aluminum toxic effects and an effective treatment for Alzheimer's disease.

Journal: Journal of inorganic biochemistry 20111101

Title: Ironing out neurodegeneration: iron chelation for neuroprotection.

Journal: Free radical biology & medicine 20111015

Title: Zinc-desferrioxamine attenuates retinal degeneration in the rd10 mouse model of retinitis pigmentosa.

Journal: Free radical biology & medicine 20111015

Title: Iron chelation therapy in thalassemia major: a systematic review with meta-analyses of 1520 patients included on randomized clinical trials.

Journal: Blood cells, molecules & diseases 20111015

Title: Iron deficiency activates pro-inflammatory signaling in macrophages and foam cells via the p38 MAPK-NF-κB pathway.

Journal: International journal of cardiology 20111006

Title: Therapeutic management of neonatal hemochromatosis: report of four cases and literature review.

Journal: Human & experimental toxicology 20111001

Title: Cold-induced injury to lung epithelial cells can be inhibited by iron chelators - implications for lung preservation.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20111001

Title: Differentiating the growing nosocomial infectious threats Ralstonia pickettii and Ralstonia insidiosa.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20111001

Title: Role of reactive oxygen species in the early stages of liver regeneration in streptozotocin-induced diabetic rats.

Journal: Free radical research 20111001

Title: Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20111001

Title: Bone mineral density in children with beta-thalassemia major in Diyarbakir.

Journal: Bone 20111001

Title: Genomics of iron acquisition in the plant pathogen Erwinia amylovora: insights in the biosynthetic pathway of the siderophore desferrioxamine E.

Journal: Archives of microbiology 20111001

Title: Iron poisoning: a literature-based review of epidemiology, diagnosis, and management.

Journal: Pediatric emergency care 20111001

Title: In vitro activity of deferoxamine against Porphyromonas gingivalis.

Journal: FEMS microbiology letters 20111001

Title: Iron-mediated lipid peroxidation and lipid raft disruption in low-dose silica-induced macrophage cytokine production.

Journal: Free radical biology & medicine 20110915

Title: Characterization of novel antisense HIF-1α transcripts in human cancers.

Journal: Cell cycle (Georgetown, Tex.) 20110915

Title: Desferrioxamine treatment of aceruloplasminemia: Long-term follow-up.

Journal: Movement disorders : official journal of the Movement Disorder Society 20110901

Title: Deferoxamine for advanced hepatocellular carcinoma.

Journal: The New England journal of medicine 20110811

Title: Protective effect of deferoxamine on experimental spinal cord injury in rat.

Journal: Injury 20110801

Title: Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice.

Journal: American journal of respiratory cell and molecular biology 20110801

Title: Self-reported level of and factors influencing the compliance to desferrioxamine therapy in multitransfused thalassaemias.

Journal: Journal of paediatrics and child health 20110801

Title: Proteomic identification of carbonylated proteins in 1,3-dinitrobenzene neurotoxicity.

Journal: Neurotoxicology 20110801

Title: Ferritin heavy chain-mediated iron homoeostasis regulates expression of IL-10 in Chlamydia trachomatis-infected HeLa cells.

Journal: Cell biology international 20110801

Title: Trypanosoma cruzi: desferrioxamine decreases mortality and parasitemia in infected mice through a trypanostatic effect.

Journal: Experimental parasitology 20110801

Title: Increasing vascularity to improve healing of a segmental defect of the rat femur.

Journal: Journal of orthopaedic trauma 20110801

Title: [Deferoxamine induces apoptosis of K562 cells].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20110801

Title: Iron chelation with deferasirox in adult and pediatric patients with thalassemia major: efficacy and safety during 5 years' follow-up.

Journal: Blood 20110728

Title: Metal ion-mobilizing additives for comprehensive detection of femtomole amounts of phosphopeptides by reversed phase LC-MS.

Journal: Amino acids 20110701

Title: Optical coherence tomography in desferrioxamine ocular toxicity: a place in screening and monitoring?

Journal: Eye (London, England) 20110701

Title: Evaluation of myocardial and hepatic iron loading by MRI T2* in multi-transfused patients with repeated blood loss as compared to thalassaemia major patients and controls.

Journal: Blood transfusion = Trasfusione del sangue 20110701

Title: Health-related quality of life in Thai thalassemic children treated with iron chelation.

Journal: The Southeast Asian journal of tropical medicine and public health 20110701

Title: Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells.

Journal: Toxicology letters 20110624

Title: Mechanism and kinetics of ligand exchange between ferric citrate and desferrioxamine B.

Journal: The journal of physical chemistry. A 20110602

Title: HFE polymorphisms affect cellular glutamate regulation.

Journal: Neurobiology of aging 20110601

Title: Role of deferoxamine on enzymatic stress markers in an animal model of Alzheimer's disease after chronic aluminum exposure.

Journal: Biological trace element research 20110601

Title: Prophylactic neuroprotection against stroke: low-dose, prolonged treatment with deferoxamine or deferasirox establishes prolonged neuroprotection independent of HIF-1 function.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110601

Title: A-to-I RNA editing is induced upon hypoxia.

Journal: Shock (Augusta, Ga.) 20110601

Title: Implementation of 89Zr production and in vivo imaging of B-cells in mice with 89Zr-labeled anti-B-cell antibodies by small animal PET/CT.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20110601

Title: Effect of oxygen concentrations on sodium iodide symporter expression and iodide uptake and hCG expression in human choriocarcinoma BeWo cells.

Journal: American journal of physiology. Endocrinology and metabolism 20110601

Title: Effects of glutathione, Trolox and desferrioxamine on hemoglobin-induced protein oxidative damage: anti-oxidant or pro-oxidant?

Journal: European journal of pharmacology 20110601

Title: Fl-DFO molecules@mesoporous silica materials: highly sensitive and selective nanosensor for dosing with iron ions.

Journal: Journal of colloid and interface science 20110601

Title: Split-liver procedure and inflammatory response: improvement by pharmacological preconditioning.

Journal: The Journal of surgical research 20110601

Title: Estradiol worsens the syndrome of ischemia-reperfusion injury in an experimental lung transplantation model.

Journal: Lung 20110601

Title: Protective effects of deferoxamine mesylate preconditioning on pancreatic tissue in orthotopic liver autotransplantation in rats.

Journal: Transplantation proceedings 20110601

Title: [The inhibition effect of DFO alone and in combination with ATO on xenograft tumor growth of HL-60 cells in nude mice and its possible mechanism].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110601

Title: Novel cytochrome p450 bioactivation of a terminal phenyl acetylene group: formation of a one-carbon loss benzaldehyde and other oxidative products in the presence of N-acetyl cysteine or glutathione.

Journal: Chemical research in toxicology 20110516

Title: Antioxidant treatment reverses organ failure in rat model of sepsis: role of antioxidant enzymes imbalance, neutrophil infiltration, and oxidative stress.

Journal: The Journal of surgical research 20110515

Title: The purpose of the HIF-1/PHD feedback loop: to limit mTOR-induced HIF-1α.

Journal: Cell cycle (Georgetown, Tex.) 20110515

Title: Iron toxicity in mice with collagenase-induced intracerebral hemorrhage.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110501

Title: In vitro antimalarial activity of ICL670: a further proof of the correlation between inhibition of β-hematin formation and of peroxidative degradation of hemin.

Journal: Experimental parasitology 20110501

Title: Comparing the potential renal protective activity of desferrioxamine B and the novel chelator desferrioxamine B-N-(3-hydroxyadamant-1-yl)carboxamide in a cell model of myoglobinuria.

Journal: The Biochemical journal 20110501

Title: Effects of chelating agent and environmental stresses on microbial biofilms: relevance to clinical microbiology.

Journal: Journal of applied microbiology 20110501

Title: Antioxidant treatment attenuates intestinal mucosal damage and gut barrier dysfunction after major hepatectomy. Study in a porcine model.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20110501

Title: Iron homeostasis and fire blight susceptibility in transgenic pear plants overexpressing a pea ferritin gene.

Journal: Plant science : an international journal of experimental plant biology 20110501

Title: In vitro analysis of iron chelating activity of flavonoids.

Journal: Journal of inorganic biochemistry 20110501

Title: Iron chelation adherence to deferoxamine and deferasirox in thalassemia.

Journal: American journal of hematology 20110501

Title: Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds.

Journal: FEBS letters 20110420

Title: Quercetin-iron chelates are transported via glucose transporters.

Journal: Free radical biology & medicine 20110415

Title: Size-dependent Pb sorption to nanohematite in the presence and absence of a microbial siderophore.

Journal: Environmental science & technology 20110415

Title: Inhibition of mitochondrial respiratory chain in the brain of rats after hepatic failure induced by acetaminophen.

Journal: Molecular and cellular biochemistry 20110401

Title: Facile labelling of an anti-epidermal growth factor receptor Nanobody with 68Ga via a novel bifunctional desferal chelate for immuno-PET.

Journal: European journal of nuclear medicine and molecular imaging 20110401

Title: Deferoxamine promotes angiogenesis via the activation of vascular endothelial cell function.

Journal: Atherosclerosis 20110401

Title: Magnitude of enhanced permeability and retention effect in tumors with different phenotypes: 89Zr-albumin as a model system.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110401

Title: [Effect of desferrioxamine on K562/A02 cell line and its mechanism].

Journal: Zhongguo shi yan xue ye xue za zhi 20110401

Title: Contribution of hypoxia-inducible factor-1α to transcriptional regulation of vascular endothelial growth factor in bovine developing luteal cells.

Journal: Animal science journal = Nihon chikusan Gakkaiho 20110401

Title: Chelators to the rescue: different horses for different courses!

Journal: Chemical research in toxicology 20110321

Title: Iron sensitizes keratinocytes and fibroblasts to UVA-mediated matrix metalloproteinase-1 through TNF-α and ERK activation.

Journal: Experimental dermatology 20110301

Title: Leishmania chagasi: effect of the iron deficiency on the infection in BALB/c mice.

Journal: Experimental parasitology 20110301

Title: Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis.

Journal: Cell death & disease 20110301

Title: Iron chelation down-regulates dopamine transporter expression by decreasing mRNA stability and increasing endocytosis in N2a cells.

Journal: Experimental cell research 20110215

Title: Additive effect of tetramethylpyrazine and deferoxamine in the treatment of spinal cord injury caused by aortic cross-clamping in rats.

Journal: Spinal cord 20110201

Title: T-type calcium channel as a portal of iron uptake into cardiomyocytes of beta-thalassemic mice.

Journal: European journal of haematology 20110201

Title: Role of iron in brain injury after intraventricular hemorrhage.

Journal: Stroke 20110201

Title: Clinically available iron chelators induce neuroprotection in the 6-OHDA model of Parkinson's disease after peripheral administration.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20110201

Title: Non-reductive iron release from horse spleen ferritin using desferoxamine chelation.

Journal: Journal of inorganic biochemistry 20110201

Title: Iron chelation in thalassemia: time to reconsider our comfort zones.

Journal: Expert review of hematology 20110201

Title: Iron overload and allogeneic hematopoietic stem-cell transplantation.

Journal: Expert review of hematology 20110201

Title: Iron-chelating therapy for transfusional iron overload.

Journal: The New England journal of medicine 20110113

Title: Deferasirox, deferiprone and desferrioxamine treatment in thalassemia major patients: cardiac iron and function comparison determined by quantitative magnetic resonance imaging.

Journal: Haematologica 20110101

Title: Cellular iron depletion weakens induction of heme oxygenase-1 by cadmium.

Journal: The international journal of biochemistry & cell biology 20110101

Title: Free radical signalling underlies inhibition of CaV3.2 T-type calcium channels by nitrous oxide in the pain pathway.

Journal: The Journal of physiology 20110101

Title: Increased oxidative stress and iron overload in Jordanian β-thalassemic children.

Journal: Hemoglobin 20110101

Title: Aplastic anaemia in pregnancy.

Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20110101

Title: Improvement of rat islet viability during transplantation: validation of pharmacological approach to induce VEGF overexpression.

Journal: Cell transplantation 20110101

Title: Role of a Fur homolog in iron metabolism in Nitrosomonas europaea.

Journal: BMC microbiology 20110101

Title: Quantitative proteomics identifies the Myb-binding protein p160 as a novel target of the von Hippel-Lindau tumor suppressor.

Journal: PloS one 20110101

Title: Identification of genes, desR and desA, required for utilization of desferrioxamine B as a xenosiderophore in Vibrio furnissii.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Induction of hypoxia inducible factor (HIF-1α) in rat kidneys by iron chelation with the hydroxypyridinone, CP94.

Journal: Biochimica et biophysica acta 20110101

Title: Efficacy, compliance and toxicity factors are affecting the rate of normalization of body iron stores in thalassemia patients using the deferiprone and deferoxamine combination therapy.

Journal: Hemoglobin 20110101

Title: Intermediate-term evaluation of a pratical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac t2*.

Journal: Hemoglobin 20110101

Title: Sequential alternating deferiprone and deferoxamine treatment compared to deferiprone monotherapy: main findings and clinical follow-up of a large multicenter randomized clinical trial in -thalassemia major patients.

Journal: Hemoglobin 20110101

Title: Hypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2.

Journal: Cell adhesion & migration 20110101

Title: Iron-chelating therapies in a transfusion-dependent thalassaemia population in Thailand: a cost-effectiveness study.

Journal: Clinical drug investigation 20110101

Title: Evaluation of ischemia-reperfusion liver injury by near-infrared spectroscopy in an experimental swine model: the effect of desferoxamine.

Journal: Journal of investigative surgery : the official journal of the Academy of Surgical Research 20110101

Title: Major beta-thalassemia, use of desferiexamine and renal proximal tubular damage.

Journal: Bratislavske lekarske listy 20110101

Title: Deferoxamine reduces early brain injury following subarachnoid hemorrhage.

Journal: Acta neurochirurgica. Supplement 20110101

Title: Iron accumulation and DNA damage in a pig model of intracerebral hemorrhage.

Journal: Acta neurochirurgica. Supplement 20110101

Title: Hemoglobin expression in neurons and glia after intracerebral hemorrhage.

Journal: Acta neurochirurgica. Supplement 20110101

Title: Deferoxamine reduces cavity size in the brain after intracerebral hemorrhage in aged rats.

Journal: Acta neurochirurgica. Supplement 20110101

Title: Deferoxamine affects heat shock protein expression in heart after intracerebral hemorrhage in aged rats.

Journal: Acta neurochirurgica. Supplement 20110101

Title: Effect of deferiprone or deferoxamine on right ventricular function in thalassemia major patients with myocardial iron overload.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

Title: Clinicopathological and radiological study of Egyptian β-thalassemia intermedia and β-thalassemia major patients: relation to complications and response to therapy.

Journal: Hemoglobin 20110101

Title: Chelation therapy with desferrioxamine does not normalize ferritin level but attenuates oxidative damage and improves total antioxidant level in Malaysian Chinese beta-thalassaemia major patients.

Journal: The West Indian medical journal 20110101

Title: Do oral aluminium phosphate binders cause accumulation of aluminium to toxic levels?

Journal: BMC nephrology 20110101

Title: Synthesis of biocompatible poly(ɛ-caprolactone)- block-poly(propylene adipate) copolymers appropriate for drug nanoencapsulation in the form of core-shell nanoparticles.

Journal: International journal of nanomedicine 20110101

Title: Iron species-mediated dopamine oxidation, proteasome inhibition, and dopaminergic cell demise: implications for iron-related dopaminergic neuron degeneration.

Journal: Free radical biology & medicine 20101215

Title: Safety and efficacy of high dose intravenous desferrioxamine for reduction of iron overload in sickle cell disease.

Journal: Pediatric blood & cancer 20101215

Title: Mimic hypoxia improves angiogenesis in ischaemic random flaps.

Journal: Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20101201

Title: Plasma membrane ferric reductase activity of iron-limited algal cells is inhibited by ferric chelators.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Iron overload in thalassemia and related conditions: therapeutic goals and assessment of response to chelation therapies.

Journal: Hematology/oncology clinics of North America 20101201

Title: Manual erythroexchange for chronic transfusion therapy in patients with sickle cell syndromes unresponsive to hydroxyurea: a long-term follow-up.

Journal: American journal of hematology 20101201

Title: Production of desferrioxamine B (Desferal) using corn steep liquor in Streptomyces pilosus.

Journal: Pakistan journal of biological sciences : PJBS 20101201

Title: Combining two orally active iron chelators for thalassemia.

Journal: Annals of hematology 20101101

Title: Reduction of body iron stores to normal range levels in thalassaemia by using a deferiprone/deferoxamine combination and their maintenance thereafter by deferiprone monotherapy.

Journal: European journal of haematology 20101101

Title: Iron and early brain injury after subarachnoid hemorrhage.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20101101

Title: Hemoglobin and iron handling in brain after subarachnoid hemorrhage and the effect of deferoxamine on early brain injury.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20101101

Title: Role of Nitrosomonas europaea NitABC iron transporter in the uptake of Fe3+-siderophore complexes.

Journal: Archives of microbiology 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: [Guidelines for diagnosis and treatment of secondary iron overload in patients with congenital anemia].

Journal: Klinische Padiatrie 20101101

Title: The impact of previous or concomitant IFN therapy on deferiprone-induced agranulocytosis and neutropenia: a retrospective study.

Journal: Expert opinion on drug safety 20101101

Title: Macular vitelliform lesion in desferrioxamine-related retinopathy.

Journal: Documenta ophthalmologica. Advances in ophthalmology 20101001

Title: Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1 alpha and induction of autophagy in SH-SY5Y cells.

Journal: Neurochemistry international 20101001

Title: Relation of chelation regimes to cardiac mortality and morbidity in patients with thalassaemia major: an observational study from a large Greek Unit.

Journal: European journal of haematology 20101001

Title: Iron chelation therapy for patients with sickle cell disease and iron overload.

Journal: American journal of hematology 20101001

Title: An update on disordered iron metabolism and iron overload.

Journal: Hematology (Amsterdam, Netherlands) 20101001

Title: Distinct extracytoplasmic siderophore binding proteins recognize ferrioxamines and ferricoelichelin in Streptomyces coelicolor A3(2).

Journal: Biochemistry 20100921

Title: Sterol regulatory element-binding protein (SREBP)-1-mediated lipogenesis is involved in cell senescence.

Journal: The Journal of biological chemistry 20100917

Title: Aluminum does not enhance beta-amyloid toxicity in rat hippocampal cultures.

Journal: Brain research 20100917

Title: Inhibition of osteoclastogenesis by prolyl hydroxylase inhibitor dimethyloxallyl glycine.

Journal: Journal of bone and mineral metabolism 20100901

Title: Microfluidic dissociation and clearance of Alzheimer's beta-amyloid aggregates.

Journal: Biomaterials 20100901

Title: Beneficial effects of desferrioxamine on encapsulated human islets--in vitro and in vivo study.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100901

Title: Porphyria cutanea tarda in a chronic hemodialysis patient.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100901

Title: Removal of Fe3+ and Zn2+ from plasma metalloproteins by iron chelating therapeutics depicted with SEC-ICP-AES.

Journal: Dalton transactions (Cambridge, England : 2003) 20100828

Title: Chelation of intracellular iron enhances endothelial barrier function: a role for vitamin C?

Journal: Archives of biochemistry and biophysics 20100815

Title: Increased survival and reversion of iron-induced cardiac disease in patients with thalassemia major receiving intensive combined chelation therapy as compared to desferoxamine alone.

Journal: Blood cells, molecules & diseases 20100815

Title: Heme oxygenase-1 contributes to pathology associated with thrombin-induced striatal and cortical injury in organotypic slice culture.

Journal: Brain research 20100806

Title: Deferasirox for managing transfusional iron overload in people with sickle cell disease.

Journal: The Cochrane database of systematic reviews 20100804

Title: Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma.

Journal: International journal of oral and maxillofacial surgery 20100801

Title: Effects of iron chelators, iron salts, and iron oxide nanoparticles on the proliferation and the iron content of oligodendroglial OLN-93 cells.

Journal: Neurochemical research 20100801

Title: New golden era of chelation therapy in thalassaemia: the achievement and maintenance of normal range body iron stores.

Journal: British journal of haematology 20100801

Title: Synthesis and characterization of a triazine dendrimer that sequesters iron(III) using 12 desferrioxamine B groups.

Journal: Bioorganic & medicinal chemistry 20100801

Title: More pieces to the iron chelation puzzle.

Journal: Translational research : the journal of laboratory and clinical medicine 20100801

Title: Mechanisms for the shuttling of plasma non-transferrin-bound iron (NTBI) onto deferoxamine by deferiprone.

Journal: Translational research : the journal of laboratory and clinical medicine 20100801

Title: Increase of reactive oxygen species by desferrioxamine during experimental Chagas' disease.

Journal: Redox report : communications in free radical research 20100801

Title: Pathogenesis and management of iron toxicity in thalassemia.

Journal: Annals of the New York Academy of Sciences 20100801

Title: Deferiprone.

Journal: Annals of the New York Academy of Sciences 20100801

Title: Combined iron chelation therapy.

Journal: Annals of the New York Academy of Sciences 20100801

Title: Treatment options for thalassemia patients with osteoporosis.

Journal: Annals of the New York Academy of Sciences 20100801

Title: How I treat hemochromatosis.

Journal: Blood 20100722

Title: Effects of desferoxamine-induced hypoxia on neuronal human mu-opioid receptor gene expression.

Journal: Biochemical and biophysical research communications 20100716

Title: Hypoxia inducible factor-1 improves the negative functional effects of natriuretic peptide and nitric oxide signaling in hypertrophic cardiac myocytes.

Journal: Life sciences 20100703

Title: Investigation of enhancement effects of nicotine on cholinergic neurotransmission in isolated rabbit gastric fundus: role of antioxidants.

Journal: Autonomic & autacoid pharmacology 20100701

Title: Does iron chelation therapy improve survival in regularly transfused lower risk MDS patients? A multicenter study by the GFM (Groupe Francophone des Myélodysplasies).

Journal: Leukemia research 20100701

Title: Combined chelation therapy in thalassemia major with deferiprone and desferrioxamine: a retrospective study.

Journal: European journal of haematology 20100701

Title: Iron chelation therapy in MDS: does it improve survival?

Journal: Leukemia research 20100701

Title: Metals in air pollution particles decrease whole-blood coagulation time.

Journal: Inhalation toxicology 20100701

Title: Stimulation of proliferation in the colorectal mucosa by gastrin precursors is blocked by desferrioxamine.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100701

Title: Genomic and phenotypic characterization of a nonpigmented variant of Pantoea vagans biocontrol strain C9-1 lacking the 530-kb megaplasmid pPag3.

Journal: FEMS microbiology letters 20100701

Title: Retrospective study on the combination of desferrioxamine and deferasirox for treatment of iron-overloaded thalassemic patients: first evidence of more than 2 years.

Journal: Journal of pediatric hematology/oncology 20100701

Title: Introduction of higher doses of deferasirox: better efficacy but not effective iron removal from the heart and increased risks of serious toxicities.

Journal: Expert opinion on drug safety 20100701

Title: Cerenkov luminescence imaging of medical isotopes.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100701

Title: Modulation of inflammatory response after spinal cord trauma with deferoxamine, an iron chelator.

Journal: Free radical research 20100601

Title: Deferoxamine mesylate is toxic for retinal pigment epithelium cells in vitro, and its toxicity is mediated by p38.

Journal: Cutaneous and ocular toxicology 20100601

Title: Inhibition of mitochondrial respiratory chain in the brain of rats after renal ischemia is prevented by N-acetylcysteine and deferoxamine.

Journal: Metabolic brain disease 20100601

Title: Daily alternating deferasirox and deferiprone therapy for 'hard-to-chelate' beta-thalassemia major patients.

Journal: American journal of hematology 20100601

Title: Maintenance of normal range body iron store levels for up to 4.5 years in thalassemia major patients using deferiprone monotherapy.

Journal: Hemoglobin 20100601

Title: Effect of combined chelation therapy with deferiprone and deferoxamine on left ventricular diastolic function in adult beta-thalassemia major patients.

Journal: Hemoglobin 20100601

Title: Incidence of hepatocellular carcinoma in a thalassemia unit.

Journal: Hemoglobin 20100601

Title: The role of iron and chelators on infections in iron overload and non iron loaded conditions: prospects for the design of new antimicrobial therapies.

Journal: Hemoglobin 20100601

Title: Iron chelation for amelioration of liver ischemia-reperfusion injury.

Journal: Hemoglobin 20100601

Title: Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation.

Journal: Blood 20100527

Title: Role of oxidative stress and MAPK signaling in reference moist smokeless tobacco-induced HOK-16B cell death.

Journal: Toxicology letters 20100519

Title: Iron-mediated oxidative stress plays an essential role in ferritin-induced cell death.

Journal: Free radical biology & medicine 20100515

Title: Preconditioning protects against oxidative injury involving hypoxia-inducible factor-1 and vascular endothelial growth factor in cultured astrocytes.

Journal: European journal of pharmacology 20100510

Title: Comparison of low-dose deferoxamine versus standard-dose deferoxamine for treatment of aluminium overload among haemodialysis patients.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100501

Title: Iron chelator deferoxamine alters iron-regulatory genes and proteins and suppresses osteoblast phenotype in fetal rat calvaria cells.

Journal: Bone 20100501

Title: Iron chelation therapy in Upper Egyptian transfusion-dependent pediatric homozygous beta-thalassemia major: impact on serum L-carnitine/free fatty acids, osteoprotegerin/the soluble receptor activator of nuclear factor-kappabeta ligand systems, and bone mineral density.

Journal: Journal of pediatric hematology/oncology 20100501

Title: The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice.

Journal: Experimental biology and medicine (Maywood, N.J.) 20100501

Title: Iron overload indices rise linearly with transfusion rate in patients with sickle cell disease.

Journal: Blood 20100408

Title: Light-induced cytotoxicity after aminolevulinic acid treatment is mediated by heme and not by iron.

Journal: Journal of photochemistry and photobiology. B, Biology 20100402

Title: Transport of iron chelators and chelates across MDCK cell monolayers: implications for iron excretion during chelation therapy.

Journal: International journal of hematology 20100401

Title: Effects of N-acetylcysteine/deferoxamine, taurine and RC-3095 on respiratory chain complexes and creatine kinase activities in rat brain after sepsis.

Journal: Neurochemical research 20100401

Title: Iron chelation therapy in myelodysplastic syndromes.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100401

Title: Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine.

Journal: Nature protocols 20100401

Title: Hypoxia inducible factor-1 protects against nitrate tolerance and stunning in rabbit cardiac myocytes.

Journal: Cardiovascular drugs and therapy 20100401

Title: Siderophores from neighboring organisms promote the growth of uncultured bacteria.

Journal: Chemistry & biology 20100326

Title: MiRNA-26b regulates the expression of cyclooxygenase-2 in desferrioxamine-treated CNE cells.

Journal: FEBS letters 20100305

Title: Desferrioxamine shows different potentials for enhancing 5-aminolaevulinic acid-based photodynamic therapy in several cutaneous cell lines.

Journal: Lasers in medical science 20100301

Title: PKB/Akt activation inhibits p53-mediated HIF1A degradation that is independent of MDM2.

Journal: Journal of cellular physiology 20100301

Title: Comparison of the prophylactic effect of silymarin and deferoxamine on iron overload-induced hepatotoxicity in rat.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20100301

Title: Studies on the redox characteristics of ferrioxamine E.

Journal: Chemistry & biodiversity 20100301

Title: Reaction of ferritin with hydrogen peroxide induces lipid peroxidation.

Journal: BMB reports 20100301

Title: Manipulation of iron transporter genes results in the suppression of human and mouse mammary adenocarcinomas.

Journal: Anticancer research 20100301

Title: The impact of desferrioxamine postallogeneic hematopoietic cell transplantation in relapse incidence and disease-free survival: a retrospective analysis.

Journal: Transplantation 20100227

Title: Conjugates of desferrioxamine B (DFOB) with derivatives of adamantane or with orally available chelators as potential agents for treating iron overload.

Journal: Journal of medicinal chemistry 20100211

Title: Iron overload and chelation therapy in patients with low-risk myelodysplastic syndromes with transfusion requirements.

Journal: Annals of hematology 20100201

Title: p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging.

Journal: European journal of nuclear medicine and molecular imaging 20100201

Title: Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major.

Journal: British journal of haematology 20100201

Title: Deferoxamine, the newly developed iron chelator LK-614 and N-alpha-acetyl-histidine in myocardial protection.

Journal: Interactive cardiovascular and thoracic surgery 20100201

Title: Deferoxamine treatment for intracerebral hemorrhage in aged rats: therapeutic time window and optimal duration.

Journal: Stroke 20100201

Title: Synthesis and biological properties of iron chelators based on a bis-2-(2-hydroxy-phenyl)-thiazole-4-carboxamide or -thiocarboxamide (BHPTC) scaffold.

Journal: Bioorganic & medicinal chemistry 20100115

Title: Failure of deferoxamine, an iron chelator, to improve outcome after collagenase-induced intracerebral hemorrhage in rats.

Journal: Brain research 20100114

Title: The effects of hypoxia/reoxygenation on the physiological behaviour of U373-MG astrocytes.

Journal: Neurochemical research 20100101

Title: Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model.

Journal: Innate immunity 20100101

Title: Effect of iron chelators on labile iron and oxidative status of thalassaemic erythroid cells.

Journal: Acta haematologica 20100101

Title: Macrophage-inflammatory protein-3alpha/CCL-20 is transcriptionally induced by the iron chelator desferrioxamine in human mononuclear phagocytes through nuclear factor (NF)-kappaB.

Journal: Molecular immunology 20100101

Title: Deferoxamine iron chelation increases delta-aminolevulinic acid induced protoporphyrin IX in xenograft glioma model.

Journal: Photochemistry and photobiology 20100101

Title: Nanoparticle and iron chelators as a potential novel Alzheimer therapy.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: HIF-1alpha dysfunction in diabetes.

Journal: Cell cycle (Georgetown, Tex.) 20100101

Title: Measuring the pharmacodynamic effects of a novel Hsp90 inhibitor on HER2/neu expression in mice using Zr-DFO-trastuzumab.

Journal: PloS one 20100101

Title: Deferoxamine versus combined therapy for chelating liver, spleen and bone marrow iron in beta-thalassemic patients: a quantitative magnetic resonance imaging study.

Journal: Hemoglobin 20100101

Title: Renal dysfunction in patients with beta-thalassemia major receiving iron chelation therapy either with deferoxamine and deferiprone or with deferasirox.

Journal: Acta haematologica 20100101

Title: Multiple transfused thalassemia major: ocular manifestations in a hospital-based population.

Journal: Indian journal of ophthalmology 20100101

Title: pH-Dependent metal ion toxicity influences the antibacterial activity of two natural mineral mixtures.

Journal: PloS one 20100101

Title: Potent inhibition of tumoral hypoxia-inducible factor 1alpha by albendazole.

Journal: BMC cancer 20100101

Title: Right ventricular volumes and function in thalassemia major patients in the absence of myocardial iron overload.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20100101

Title: [Epidemiological and economic aspects of chelating therapy in the therapeutic center of thalassemia in Morocco].

Journal: Revue medicale de Bruxelles 20100101

Title: Ocular abnormalities in patients with beta thalassemia on transfusion and chelation therapy: our experience.

Journal: Indian journal of ophthalmology 20100101

Title: [Diamond-Blackfan anemia. Case report].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20100101

Title: Cost effectiveness of deferasirox compared to desferrioxamine in the treatment of iron overload in lower-risk, transfusion-dependent myelodysplastic syndrome patients.

Journal: Journal of medical economics 20100101

Title: Amyloid-β peptide fibrils induce nitro-oxidative stress in neuronal cells.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: Recurrent pregnancy-induced diabetes insipidus in a woman with hemochromatosis.

Journal: Endocrine journal 20100101

Title: The effects of deferoxamine mesylate on iron elimination after blood transfusion in neonatal foals.

Journal: Journal of veterinary internal medicine 20100101

Title: Imaging and treating tumor vasculature with targeted radiolabeled carbon nanotubes.

Journal: International journal of nanomedicine 20100101

Title: Antioxidants protect keratinocytes against M. ulcerans mycolactone cytotoxicity.

Journal: PloS one 20100101

Title: Cardiac events and cardiac T2* in Egyptian children and young adults with beta-thalassemia major taking deferoxamine.

Journal: Hematology/oncology and stem cell therapy 20100101

Title: A lanthanide-based chemosensor for bioavailable Fe3+ using a fluorescent siderophore: an assay displacement approach.

Journal: Sensors (Basel, Switzerland) 20100101

Title: Effects of N-acetylcysteine, deferoxamine and selenium on doxorubicin-induced hepatotoxicity.

Journal: Biological trace element research 20091201

Title: Remission from transfusion-dependence in a patient with congenital dyserythropoietic anemia (CDA) and increased intensity of iron chelation.

Journal: Pediatric blood & cancer 20091201

Title: Daily labile plasma iron as an indicator of chelator activity in Thalassaemia major patients.

Journal: British journal of haematology 20091201

Title: Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone.

Journal: Haematologica 20091201

Title: Early cardiac iron overload in children with transfusion-dependent anemias.

Journal: Haematologica 20091201

Title: Different roles for anti-sigma factors in siderophore signalling pathways of Pseudomonas aeruginosa.

Journal: Molecular microbiology 20091201

Title: Hypoxia-inducible factor-1alpha blocks differentiation of malignant gliomas.

Journal: The FEBS journal 20091201

Title: Socio-psychological impact of infused iron chelation therapy with deferoxamine in metropolitan France: ISOSFER study results.

Journal: Hematology (Amsterdam, Netherlands) 20091201

Title: A comparative study on the enhancement efficacy of specific and non-specific iron chelators for protoporphyrin IX production and photosensitization in HaCat cells.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20091201

Title: Iron toxicity: optimizing chelation therapy across transfusion-dependent anaemias. Introduction.

Journal: Blood reviews 20091201

Title: Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury.

Journal: Blood 20091119

Title: Specific iron chelators determine the route of ferritin degradation.

Journal: Blood 20091112

Title: Towards the mechanism and comparative effect of diphenyl diselenide, diphenyl ditelluride and ebselen under various pathophysiological conditions in rat's kidney preparation.

Journal: Chemico-biological interactions 20091110

Title: Preventing blood-induced joint damage with the use of intra-articular iron chelators: an experimental study in rabbits.

Journal: Archives of orthopaedic and trauma surgery 20091101

Title: A case of iron overload cardiomyopathy: beneficial effects of iron chelating agent and calcium channel blocker on left ventricular dysfunction.

Journal: International heart journal 20091101

Title: Effect of iron ions on functional activity of thrombin.

Journal: Bulletin of experimental biology and medicine 20091101

Title: Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2'-deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8-dione.

Journal: The Journal of biological chemistry 20091023

Title: Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20091001

Title: Deferoxamine-induced neurite outgrowth and synapse formation in postnatal rat dorsal root ganglion (DRG) cell cultures.

Journal: European journal of cell biology 20091001

Title: An extended-release formulation of desferrioxamine for subcutaneous administration.

Journal: Drug delivery 20091001

Title: Peroxynitrite and heme protein--mediated nitrative/oxidative modification of human plasma protein: the role of free radical scavenging vs. complex forming.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20091001

Title: Standardized methods for the production of high specific-activity zirconium-89.

Journal: Nuclear medicine and biology 20091001

Title: Understanding iron overload: screening, monitoring, and caring for patients with transfusion-dependent anemias.

Journal: Clinical journal of oncology nursing 20091001

Title: Effects of deferoxamine on brain injury after transient focal cerebral ischemia in rats with hyperglycemia.

Journal: Brain research 20090929

Title: Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells.

Journal: World journal of gastroenterology 20090928

Title: Tobramycin and FDA-approved iron chelators eliminate Pseudomonas aeruginosa biofilms on cystic fibrosis cells.

Journal: American journal of respiratory cell and molecular biology 20090901

Title: Hypoxia inducible factor-1 improves the actions of positive inotropic agents in stunned cardiac myocytes.

Journal: Clinical and experimental pharmacology & physiology 20090901

Title: Intranasal deferoxamine provides increased brain exposure and significant protection in rat ischemic stroke.

Journal: The Journal of pharmacology and experimental therapeutics 20090901

Title: New insight into the influence of carob extract and gallic acid on hemin induced modulation of HT29 cell growth parameters.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090901

Title: Interferon-gamma induces prolyl hydroxylase (PHD)3 through a STAT1-dependent mechanism in human endothelial cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090901

Title: Aging impairs flow-induced dilation in coronary arterioles: role of NO and H(2)O(2).

Journal: American journal of physiology. Heart and circulatory physiology 20090901

Title: Two overlapping antiparallel genes encoding the iron regulator DmdR1 and the Adm proteins control siderophore [correction of sedephore] and antibiotic biosynthesis in Streptomyces coelicolor A3(2).

Journal: The FEBS journal 20090901

Title: Efficacy of combined desferrioxamine and deferiprone versus single desferrioxamine therapy in patients with major thalassemia.

Journal: Archives of Iranian medicine 20090901

Title: Iron deficiency down-regulates the Akt/TSC1-TSC2/mammalian Target of Rapamycin signaling pathway in rats and in COS-1 cells.

Journal: Nutrition research (New York, N.Y.) 20090901

Title: Minocycline attenuates iron neurotoxicity in cortical cell cultures.

Journal: Biochemical and biophysical research communications 20090821

Title: Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin 'Trojan Horse' antibiotics and synthetic desferridanoxamine-antibiotic conjugates.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20090801

Title: Overexpression of mitochondrial ferritin sensitizes cells to oxidative stress via an iron-mediated mechanism.

Journal: Antioxidants & redox signaling 20090801

Title: Lipid-derived free radical production in superantigen-induced interstitial pneumonia.

Journal: Free radical biology & medicine 20090801

Title: Comparison of the effects of deferasirox, deferiprone, and deferoxamine on the growth and virulence of Vibrio vulnificus.

Journal: Transfusion 20090801

Title: Myoglobin causes oxidative stress, increase of NO production and dysfunction of kidney's mitochondria.

Journal: Biochimica et biophysica acta 20090801

Title: The mechanism of iron homeostasis in the unicellular cyanobacterium synechocystis sp. PCC 6803 and its relationship to oxidative stress.

Journal: Plant physiology 20090801

Title: Improved vessel preservation after 4 days of cold storage: experimental study in rat arteries.

Journal: Journal of vascular surgery 20090801

Title: Quality of life in transfusion-dependent thalassaemia patients on desferrioxamine treatment.

Journal: Singapore medical journal 20090801

Title: A novel function of Aft1 in regulating ferrioxamine B uptake: Aft1 modulates Arn3 ubiquitination in Saccharomyces cerevisiae.

Journal: The Biochemical journal 20090729

Title: Efficacy of the combination of N-acetylcysteine and desferrioxamine in the prevention and treatment of gentamicin-induced acute renal failure in male Wistar rats.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701

Title: Comparative mutagenic effects of structurally similar flavonoids quercetin and taxifolin on tester strains Salmonella typhimurium TA102 and Escherichia coli WP-2 uvrA.

Journal: Environmental and molecular mutagenesis 20090701

Title: Iron depletion decreases proliferation and induces apoptosis in a human colonic adenocarcinoma cell line, Caco2.

Journal: Journal of inorganic biochemistry 20090701

Title: Adenoviral infection or deferoxamine? Two approaches to overexpress VEGF in beta-cell lines.

Journal: Journal of drug targeting 20090701

Title: Acute toxicity in five dogs after ingestion of a commercial snail and slug bait containing iron EDTA.

Journal: Australian veterinary journal 20090701

Title: [Pathogenesis of transfusional iron overload and iron chelation therapy].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20090701

Title: Quantification of myocardial iron overload by cardiovascular magnetic resonance imaging T2* and review of the literature.

Journal: Clinical cardiology 20090601

Title: Desferrioxamine attenuates minor lung injury following surgical acute liver failure.

Journal: The European respiratory journal 20090601

Title: Left ventricular non-compaction in identical twins with thalassaemia and cardiac iron overload.

Journal: European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 20090601

Title: Efficacy and safety of deferasirox, an oral iron chelator, in heavily iron-overloaded patients with beta-thalassaemia: the ESCALATOR study.

Journal: European journal of haematology 20090601

Title: Desiccation tolerance in bovine sperm: a study of the effect of intracellular sugars and the supplemental roles of an antioxidant and a chelator.

Journal: Cryobiology 20090601

Title: The protective role of HO-1 and its generated products (CO, bilirubin, and Fe) in ethanol-induced human hepatocyte damage.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20090601

Title: Role of iron in the pathogenesis of cysteamine-induced duodenal ulceration in rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20090601

Title: Deferoxamine reduces intracerebral hematoma-induced iron accumulation and neuronal death in piglets.

Journal: Stroke 20090601

Title: Potential mechanism for pentachlorophenol-induced carcinogenicity: a novel mechanism for metal-independent production of hydroxyl radicals.

Journal: Chemical research in toxicology 20090601

Title: Combined therapy of silymarin and desferrioxamine in patients with beta-thalassemia major: a randomized double-blind clinical trial.

Journal: Fundamental & clinical pharmacology 20090601

Title: Effect of vitamin C, deferoxamine, quercetin and rutin against tert-butyl hydroperoxide oxidative damage in human erythrocytes.

Journal: Hematology (Amsterdam, Netherlands) 20090601

Title: Hypoxia-specific stabilization of HIF-1alpha by human papillomaviruses.

Journal: Virology 20090510

Title: Deferoxamine mimics the pattern of hypoxia-related injury at the microvasculature.

Journal: Shock (Augusta, Ga.) 20090501

Title: Desferroxamine infusion increases cerebral blood flow: a potential association with hypoxia-inducible factor-1.

Journal: Clinical science (London, England : 1979) 20090501

Title: Lactoferrin and desferrioxamine are ineffective in the treatment of Helicobacter pylori infection and may enhance H. pylori growth and gastric inflammation in mice.

Journal: Letters in applied microbiology 20090501

Title: Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090501

Title: Effects of deferoxamine on intracerebral hemorrhage-induced brain injury in aged rats.

Journal: Stroke 20090501

Title: Non-hypoxic stabilization of hypoxia-inducible factor alpha (HIF-alpha): relevance in neural progenitor/stem cells.

Journal: Neurotoxicity research 20090501

Title: Infantile iron poisoning: challenges in diagnosis and management.

Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20090501

Title: Long-term sequential deferiprone-deferoxamine versus deferiprone alone for thalassaemia major patients: a randomized clinical trial.

Journal: British journal of haematology 20090401

Title: Effect of iron-chelator deferiprone on the in vitro growth of staphylococci.

Journal: Journal of Korean medical science 20090401

Title: The induction of HIF-1 reduces astrocyte activation by amyloid beta peptide.

Journal: The European journal of neuroscience 20090401

Title: Wavelength-dependence of photoreductive dissolution of lepidocrocite (gamma-FeOOH) in the absence and presence of the siderophore DFOB.

Journal: Environmental science & technology 20090315

Title: Brain edema after intracerebral hemorrhage in rats: the role of iron overload and aquaporin 4.

Journal: Journal of neurosurgery 20090301

Title: Deferoxamine mesylate: a new hope for intracerebral hemorrhage: from bench to clinical trials.

Journal: Stroke 20090301

Title: Hepatitis B virus reactivation during combined therapy with deferiprone and desferioxamine in a hepatitis B surface antigen thalassemic carrier.

Journal: International journal of hematology 20090301

Title: Hypothermic preconditioning of endothelial cells attenuates cold-induced injury by a ferritin-dependent process.

Journal: Free radical biology & medicine 20090301

Title: Specific inhibition of hypoxia inducible factor 1 exaggerates cell injury induced by in vitro ischemia through deteriorating cellular redox environment.

Journal: Journal of neurochemistry 20090301

Title: Sequential antiviral and iron chelation treatment in a teenage boy with congenital anemia, chronic hepatitis C, and secondary hemosiderosis.

Journal: Journal of pediatric gastroenterology and nutrition 20090301

Title: The influence of iron loading and iron chelation on the proliferation and telomerase activity of human peripheral blood mononuclear cells.

Journal: Iranian journal of immunology : IJI 20090301

Title: Iron is a potential key mediator of glutamate excitotoxicity in spinal cord motor neurons.

Journal: Brain research 20090227

Title: Combination of deferoxamine and erythropoietin: therapy for hypoxia-ischemia-induced brain injury in the neonatal rat?

Journal: Neuroscience letters 20090220

Title: Regulation of growth differentiation factor 15 expression by intracellular iron.

Journal: Blood 20090212

Title: In vitro chelating, cytotoxicity, and blood compatibility of degradable poly(ethylene glycol)-based macromolecular iron chelators.

Journal: Biomaterials 20090201

Title: Diminished iron concentrations increase adenosine A(2A) receptor levels in mouse striatum and cultured human neuroblastoma cells.

Journal: Experimental neurology 20090201

Title: Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates.

Journal: Toxicology and applied pharmacology 20090201

Title: Activation of c-Jun-N-terminal kinase in a rat model of intracerebral hemorrhage: the role of iron.

Journal: Neuroscience research 20090201

Title: Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20090101

Title: Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes.

Journal: Journal of molecular and cellular cardiology 20090101

Title: Regulation of transferrin receptor 2 in human cancer cell lines.

Journal: Blood cells, molecules & diseases 20090101

Title: Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional haemosiderosis) in patients suffering with chronic anaemia: a systematic review and economic evaluation.

Journal: Health technology assessment (Winchester, England) 20090101

Title: The novel iron chelator, 2-pyridylcarboxaldehyde 2-thiophenecarboxyl hydrazone, reduces catecholamine-mediated myocardial toxicity.

Journal: Chemical research in toxicology 20090101

Title: Effects of the microbial siderophore DFO-B on Pb and Cd speciation in aqueous solution.

Journal: Environmental science & technology 20090101

Title: Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1.

Journal: Journal of neuroinflammation 20090101

Title: Improving survival with deferiprone treatment in patients with thalassemia major: a prospective multicenter randomised clinical trial under the auspices of the Italian Society for Thalassemia and Hemoglobinopathies.

Journal: Blood cells, molecules & diseases 20090101

Title: Hypoxia regulates human lung fibroblast proliferation via p53-dependent and -independent pathways.

Journal: Respiratory research 20090101

Title: Desferrioxamine as immunomodulatory agent during microorganism infection.

Journal: Current pharmaceutical design 20090101

Title: Heme oxygenase-1 and its metabolites affect pancreatic tumor growth in vivo.

Journal: Molecular cancer 20090101

Title: The efficacy of iron chelator regimes in reducing cardiac and hepatic iron in patients with thalassaemia major: a clinical observational study.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101

Title: Iron chelators in medicinal applications - chemical equilibrium considerations in pharmaceutical activity.

Journal: Current medicinal chemistry 20090101

Title: Oral iron chelators.

Journal: Annual review of medicine 20090101

Title: Effects of 50 Hz electromagnetic fields on rat cortical synaptosomes.

Journal: Toxicology and industrial health 20090101

Title: Advances in the prevention and treatment are changing thalassemia from a fatal to a chronic disease. experience from a Cyprus model and its use as a paradigm for future applications.

Journal: Hemoglobin 20090101

Title: Update on thalassemia treatment in Taiwan, including bone marrow transplantation, chelation therapy, and cardiomyopathy treatment effects.

Journal: Hemoglobin 20090101

Title: Uses and limitations of serum ferritin, magnetic resonance imaging T2 and T2* in the diagnosis of iron overload and in the ferrikinetics of normalization of the iron stores in thalassemia using the International Committee on Chelation deferiprone/deferoxamine combination protocol.

Journal: Hemoglobin 20090101

Title: A practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac T2*.

Journal: Hemoglobin 20090101

Title: A new era in iron chelation therapy: the design of optimal, individually adjusted iron chelation therapies for the complete removal of iron overload in thalassemia and other chronically transfused patients.

Journal: Hemoglobin 20090101

Title: Effects of chelators (deferoxamine, deferiprone and deferasirox) on the growth of Klebsiella pneumoniae and Aeromonas hydrophila isolated from transfusion-dependent thalassemia patients.

Journal: Hemoglobin 20090101

Title: Risk/benefit assessment, advantages over other drugs and targeting methods in the use of deferiprone as a pharmaceutical antioxidant in iron loading and non iron loading conditions.

Journal: Hemoglobin 20090101

Title: Regulation of 5-aminolevulinic acid-mediated protoporphyrin IX accumulation in human urothelial carcinomas.

Journal: Pathobiology : journal of immunopathology, molecular and cellular biology 20090101

Title: Overview of iron chelation therapy with desferrioxamine and deferiprone.

Journal: Hemoglobin 20090101

Title: Update on survival in thalassemia major.

Journal: Hemoglobin 20090101

Title: Supportive care and chelation therapy in MDS: are we saving lives or just lowering iron?

Journal: Hematology. American Society of Hematology. Education Program 20090101

Title: Selective deficiency of HIF-1alpha in myeloid cells influences secondary intention wound healing in mouse skin.

Journal: In vivo (Athens, Greece) 20090101

Title: Local administration of DFO-loaded lipid particles improves recovery after end-to-end reconstruction of rat median nerve.

Journal: Restorative neurology and neuroscience 20090101

Title: A time-cost augmented economic evaluation of oral deferasirox versus infusional deferoxamine [corrected] for patients with iron overload in South Korea.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090101

Title: Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha.

Journal: The Biochemical journal 20081215

Title: Iron lung? New ideas about hypoxic pulmonary vasoconstriction.

Journal: The Journal of physiology 20081215

Title: TNF-alpha stimulates Akt by a distinct aPKC-dependent pathway in premalignant keratinocytes.

Journal: Experimental dermatology 20081201

Title: Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201

Title: Trypanosoma cruzi: effect of benznidazole therapy combined with the iron chelator desferrioxamine in infected mice.

Journal: Experimental parasitology 20081201

Title: The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.

Journal: The Journal of physiology 20081201

Title: Iron acquisition: a novel perspective on mucormycosis pathogenesis and treatment.

Journal: Current opinion in infectious diseases 20081201

Title: The hmuUV genes of Sinorhizobium meliloti 2011 encode the permease and ATPase components of an ABC transport system for the utilization of both haem and the hydroxamate siderophores, ferrichrome and ferrioxamine B.

Journal: Molecular microbiology 20081201

Title: Tim-2 is the receptor for H-ferritin on oligodendrocytes.

Journal: Journal of neurochemistry 20081201

Title: Desferrioxamine dehydrogenates bilirubin in two stages, leading to a 1:1 red-coloured adduct. Characterization of the products by high-performance liquid chromatography/electrospray ionization mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20081201

Title: Hypoxia decreases the expression of the two enzymes responsible for producing linear and cyclic tetrapyrroles in the heme biosynthetic pathway.

Journal: The FEBS journal 20081201

Title: Deferroxamine preconditioning promotes long-lasting retinal ischemic tolerance.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20081201

Title: Cytotoxic effects of catechol to neuroblastoma N2a cells.

Journal: General physiology and biophysics 20081201

Title: Reductive inactivation of yeast glutathione reductase by Fe(II) and NADPH.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20081101

Title: Marrow proliferation as a cause of hearing loss in beta-thalassaemia major.

Journal: The Journal of laryngology and otology 20081101

Title: Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.

Journal: Health physics 20081101

Title: Monothiol glutaredoxin-1 is an essential iron-sulfur protein in the mitochondrion of African trypanosomes.

Journal: The Journal of biological chemistry 20081010

Title: Role of lipid-derived free radical in bleomycin-induced lung injury in mice: availability for ESR spin trap method with organic phase extraction.

Journal: Biological & pharmaceutical bulletin 20081001

Title: [Attractiveness of paroxysmal nocturnal hemoglobinuria for study].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001

Title: Signaling and apoptosis differences between severe hypoxia and desferoxamine treatment of human epithelial cells.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20081001

Title: The costs of drugs used to treat myelodysplastic syndromes following National Comprehensive Cancer Network Guidelines.

Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20081001

Title: [The effects of antioxidants on the reflex from an eye-ground and electric activity of retina during intravitreal haemorrhage].

Journal: Georgian medical news 20081001

Title: A neoplastic gene fusion mimics trans-splicing of RNAs in normal human cells.

Journal: Science (New York, N.Y.) 20080905

Title: Iron chelator differentially activates macrophage inflammatory protein-3alpha/CCL20 in immortalized and malignant human oral keratinocytes.

Journal: Archives of oral biology 20080901

Title: Long-term experience with deferasirox (ICL670), a once-daily oral iron chelator, in the treatment of transfusional iron overload.

Journal: Expert opinion on pharmacotherapy 20080901

Title: Sensory neural hearing loss in beta-thalassemia major patients treated with deferoxamine.

Journal: Pediatric hematology and oncology 20080901

Title: Corneal epithelial nuclear ferritin: developmental regulation of ferritin and its nuclear transporter ferritoid.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20080901

Title: Enhanced neurogenesis from neural progenitor cells with G1/S-phase cell cycle arrest is mediated by transforming growth factor beta1.

Journal: The European journal of neuroscience 20080901

Title: Recovery of DNA and fingerprints from touched documents.

Journal: Forensic science international. Genetics 20080901

Title: Bacterial cell wall products increases stabilization of HIF-1 alpha in an oligodendrocyte cell line preconditioned by cobalt chloride or desferrioxamine.

Journal: Journal of neuroimmunology 20080830

Title: Preconditioning with cobalt chloride or desferrioxamine protects oligodendrocyte cell line (MO3.13) from tumor necrosis factor-alpha-mediated cell death.

Journal: Journal of neuroscience research 20080815

Title: PARP-1 modulates deferoxamine-induced HIF-1alpha accumulation through the regulation of nitric oxide and oxidative stress.

Journal: Journal of cellular biochemistry 20080815

Title: Prevalence of impaired glucose metabolism in beta-thalassemic children receiving hypertransfusions with a suboptimal dosage of iron-chelating therapy.

Journal: European journal of pediatrics 20080801

Title: Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia.

Journal: Human molecular genetics 20080801

Title: Structure-based differences between the metal ion selectivity of two siderophores desferrioxamine B (DFB) and desferricoprogen (DFC): why DFC is much better Pb(II) sequestering agent than DFB?

Journal: Journal of inorganic biochemistry 20080801

Title: HIF and reactive oxygen species regulate oxidative phosphorylation in cancer.

Journal: Carcinogenesis 20080801

Title: Acute kidney injury due to deferoxamine in a renal transplant patient.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080801

Title: Adherence to desferrioxamine and deferiprone and the impact of deferiprone co-prescription in thalassaemia major patients. Does the addition of deferiprone improve adherence?

Journal: British journal of haematology 20080801

Title: Oxidative stress, erythrocyte ageing and plasma non-protein-bound iron in diabetic patients.

Journal: Free radical research 20080801

Title: Iron chelation attenuates intracranial pressure and improves survival in a swine model of acute liver failure.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080801

Title: Generation and characterization of novel local and metastatic human neuroblastoma variants.

Journal: Neoplasia (New York, N.Y.) 20080801

Title: Iron chelation therapy: clinical effectiveness, economic burden and quality of life in patients with iron overload.

Journal: Advances in therapy 20080801

Title: The effect of an iron (III) chelator, silybin, on the proliferation and cell cycle of Jurkat cells: a comparison with desferrioxamine.

Journal: European journal of pharmacology 20080728

Title: Reversion of age-related recognition memory impairment by iron chelation in rats.

Journal: Neurobiology of aging 20080701

Title: Iron chelation in thalassemia: combined or monotherapy? The Egyptian experience.

Journal: Annals of hematology 20080701

Title: Desferrioxamine-driven upregulation of angiogenic factor expression by human bone marrow stromal cells.

Journal: Journal of tissue engineering and regenerative medicine 20080701

Title: Influence of iron chelation on R1 and R2 calibration curves in gerbil liver and heart.

Journal: Magnetic resonance in medicine 20080701

Title: Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.

Journal: Molecular cancer therapeutics 20080701

Title: Iron and hepatitis C: what can we learn from thalassemia major?

Journal: Liver international : official journal of the International Association for the Study of the Liver 20080701

Title: Distortion-product otoacoustic emission: early detection in deferoxamine induced ototoxicity.

Journal: Auris, nasus, larynx 20080601

Title: Carbon monoxide reversibly alters iron homeostasis and respiratory epithelial cell function.

Journal: American journal of respiratory cell and molecular biology 20080601

Title: Early markers of renal dysfunction in patients with beta-thalassemia major.

Journal: Pediatric nephrology (Berlin, Germany) 20080601

Title: Long-term functional and protective actions of preconditioning with hypoxia, cobalt chloride, and desferrioxamine against hypoxic-ischemic injury in neonatal rats.

Journal: Pediatric research 20080601

Title: Cost-utility analysis of deferasirox compared to standard therapy with desferrioxamine for patients requiring iron chelation therapy in the United Kingdom.

Journal: Current medical research and opinion 20080601

Title: Completely different effects of desferrioxamine on hemin/nitrite/H2O2-induced bovine serum albumin nitration and oxidation.

Journal: Chemical research in toxicology 20080601

Title: Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial.

Journal: Haematologica 20080601

Title: Deferoxamine-related ocular toxicity: incidence and outcome in a pediatric population.

Journal: Retina (Philadelphia, Pa.) 20080601

Title: Promotion of osteogenesis through beta-catenin signaling by desferrioxamine.

Journal: Biochemical and biophysical research communications 20080530

Title: Effects of anionic surfactants on ligand-promoted dissolution of iron and aluminum hydroxides.

Journal: Journal of colloid and interface science 20080515

Title: Effect of N-acetylcysteine and/or deferoxamine on oxidative stress and hyperactivity in an animal model of mania.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080515

Title: The effect of n-acetylcysteine and deferoxamine on exercise-induced oxidative damage in striatum and hippocampus of mice.

Journal: Neurochemical research 20080501

Title: Autophagy after experimental intracerebral hemorrhage.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080501

Title: Hypoxia-mediated Na-K-ATPase degradation requires von Hippel Lindau protein.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501

Title: Transplantation of human neural stem cells protect against ischemia in a preventive mode via hypoxia-inducible factor-1alpha stabilization in the host brain.

Journal: Brain research 20080501

Title: Italian Society of Hematology practice guidelines for the management of iron overload in thalassemia major and related disorders.

Journal: Haematologica 20080501

Title: Mechanisms of and obstacles to iron cardiomyopathy in thalassemia.

Journal: Frontiers in bioscience : a journal and virtual library 20080501

Title: Chelation of bismuth by combining desferrioxamine and deferiprone in rats.

Journal: Toxicology and industrial health 20080501

Title: Aceruloplasminemia: a novel mutation in a family with marked phenotypic variability.

Journal: Movement disorders : official journal of the Movement Disorder Society 20080415

Title: A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells.

Journal: Toxicology and applied pharmacology 20080415

Title: Synthesis and evaluation of novel polyaminocarboxylate-based antitumor agents.

Journal: Journal of medicinal chemistry 20080410

Title: Effects of deferoxamine on blood-brain barrier disruption and VEGF in focal cerebral ischemia.

Journal: Neurological research 20080401

Title: Cutaneous zygomycosis in an infant with Pearson syndrome.

Journal: Pediatric blood & cancer 20080401

Title: Outcomes, utilization, and costs among thalassemia and sickle cell disease patients receiving deferoxamine therapy in the United States.

Journal: American journal of hematology 20080401

Title: Desferrioxamine (DFX) induces apoptosis through the p38-caspase8-Bid-Bax pathway in PHA-stimulated human lymphocytes.

Journal: Toxicology and applied pharmacology 20080401

Title: Dysregulation of hepatic iron with aging: implications for heat stress-induced oxidative liver injury.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080401

Title: Severe iron intoxication treated with exchange transfusion.

Journal: Archives of disease in childhood 20080401

Title: Desferoxamine preconditioning protects against cerebral ischemia in rats by inducing expressions of hypoxia inducible factor 1 alpha and erythropoietin.

Journal: Neuroscience bulletin 20080401

Title: Oral iron chelators.

Journal: Pediatric clinics of North America 20080401

Title: Hypoxia down-regulates CCAAT/enhancer binding protein-alpha expression in breast cancer cells.

Journal: Cancer research 20080401

Title: Complete hematopoietic recovery after continuous iron chelation therapy in a patient with severe aplastic anemia with secondary hemochromatosis.

Journal: Journal of Korean medical science 20080401

Title: Inhibition of brain creatine kinase activity after renal ischemia is attenuated by N-acetylcysteine and deferoxamine administration.

Journal: Neuroscience letters 20080321

Title: The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2alpha.

Journal: Oncogene 20080306

Title: Human skin keloid fibroblasts display bioenergetics of cancer cells.

Journal: The Journal of investigative dermatology 20080301

Title: Reactive oxygen species mediate detrusor overactivity via sensitization of afferent pathway in the bladder of anaesthetized rats.

Journal: BJU international 20080301

Title: Iron chelation by clinically relevant anthracyclines: alteration in expression of iron-regulated genes and atypical changes in intracellular iron distribution and trafficking.

Journal: Molecular pharmacology 20080301

Title: Acute kidney injury due to deferoxamine in a renal transplant patient.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080301

Title: Statin-induced heme oxygenase-1 increases NF-kappaB activation and oxygen radical production in cultured neuronal cells exposed to lipopolysaccharide.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080301

Title: Iron depletion by deferoxamine up-regulates glucose uptake and insulin signaling in hepatoma cells and in rat liver.

Journal: The American journal of pathology 20080301

Title: DHEA decreases HIF-1alpha accumulation under hypoxia in human pulmonary artery cells: potential role in the treatment of pulmonary arterial hypertension.

Journal: The Journal of steroid biochemistry and molecular biology 20080301

Title: Iron overload disorders: treatment options for patients refractory to or intolerant of phlebotomy.

Journal: Pharmacotherapy 20080301

Title: [Iron overload and iron chelation therapy in transfusion-dependent patients].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20080301

Title: High susceptibility of activated lymphocytes to oxidative stress-induced cell death.

Journal: Anais da Academia Brasileira de Ciencias 20080301

Title: Overexpression of vascular endothelial growth factor in vitro using deferoxamine: a new drug to increase islet vascularization during transplantation.

Journal: Transplantation proceedings 20080301

Title: Stroke in patients with sickle cell disease: clinical and neurological aspects.

Journal: Arquivos de neuro-psiquiatria 20080301

Title: Spermatogenesis in young adult patients with beta-thalassaemia major long-term treated with desferrioxamine.

Journal: Georgian medical news 20080301

Title: Expression pattern of E2F6 in physical and chemical hypoxia-induced apoptosis.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20080225

Title: [Beta-thalassemia major and pregnancy to term].

Journal: Medicina clinica 20080223

Title: Flavonoids induce HIF-1alpha but impair its nuclear accumulation and activity.

Journal: Free radical biology & medicine 20080215

Title: Prevention of artifactual oxidation in determination of cellular 8-oxo-7,8-dihydro-2'-deoxyguanosine by isotope-dilution LC-MS/MS with automated solid-phase extraction.

Journal: Free radical biology & medicine 20080201

Title: Attenuation of acute and chronic liver injury in rats by iron-deficient diet.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080201

Title: Improvement of the cold storage of blood vessels with a vascular preservation solution. Study in porcine aortic segments.

Journal: Journal of vascular surgery 20080201

Title: Transfusion-dependent thalassaemia: a new era.

Journal: The Medical journal of Australia 20080121

Title: Management and clinical outcomes of transfusion-dependent thalassaemia major in an Australian tertiary referral clinic.

Journal: The Medical journal of Australia 20080121

Title: Chelator-facilitated removal of iron from transferrin: relevance to combined chelation therapy.

Journal: The Biochemical journal 20080115

Title: Effect of transfusional iron intake on response to chelation therapy in beta-thalassemia major.

Journal: Blood 20080115

Title: In vitro evaluation of alternative oral contrast agents for MRI of the gastrointestinal tract.

Journal: European journal of radiology 20080101

Title: Attenuation of bleomycin-induced lung injury and oxidative stress by N-acetylcysteine plus deferoxamine.

Journal: Pulmonary pharmacology & therapeutics 20080101

Title: Simvastatin-induced heme oxygenase-1 increases apoptosis of Neuro 2A cells in response to glucose deprivation.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080101

Title: Novel near-infrared fluorescent integrin-targeted DFO analogue.

Journal: Bioconjugate chemistry 20080101

Title: Deferoxamine decreases the excitatory amino acid levels and improves the histological outcome in the hippocampus of neonatal rats after hypoxia-ischemia.

Journal: Pharmacological research 20080101

Title: Feasible identification of Staphylococcus epidermidis using desferrioxamine and fosfomycin disks.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20080101

Title: Ethical issues and risk/benefit assessment of iron chelation therapy: advances with deferiprone/deferoxamine combinations and concerns about the safety, efficacy and costs of deferasirox.

Journal: Hemoglobin 20080101

Title: Myocyte damage and loss of myofibers is the potential mechanism of iron overload toxicity in congestive cardiac failure in thalassemia. Complete reversal of the cardiomyopathy and normalization of iron load by deferiprone.

Journal: Hemoglobin 20080101

Title: Effects of combined deferiprone and deferoxamine chelation therapy on iron load indices in beta-thalassemia.

Journal: Hemoglobin 20080101

Title: Immune and neural status of thalassemic patients receiving deferiprone or combined deferiprone and deferoxamine chelation treatment.

Journal: Hemoglobin 20080101

Title: Long term comparative studies in thalassemia patients treated with deferoxamine or a deferoxamine/deferiprone combination. Identification of effective chelation therapy protocols.

Journal: Hemoglobin 20080101

Title: Effects of chelation therapy on cardiac function improvement in thalassemia patients: literature review and the Taiwanese experience.

Journal: Hemoglobin 20080101

Title: Variable inhibitory effects on the formation of dinitrosyl iron complexes by deferoxamine and salicylaldehyde isonicotinoyl hydrazone in K562 cells.

Journal: Hemoglobin 20080101

Title: Combined chelation therapy in thalassemia major for the treatment of severe myocardial siderosis with left ventricular dysfunction.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20080101

Title: Effects of deferoxamine-activated hypoxia-inducible factor-1 on the brainstem after subarachnoid hemorrhage in rats.

Journal: Neurosurgery 20080101

Title: Patient-reported outcomes of deferasirox (Exjade, ICL670) versus deferoxamine in sickle cell disease patients with transfusional hemosiderosis. Substudy of a randomized open-label phase II trial.

Journal: Acta haematologica 20080101

Title: Hypoxia inducible factor-1 improves the actions of nitric oxide and natriuretic peptides after simulated ischemia-reperfusion.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: Deferoxamine induces endoplasmic reticulum stress in PC12 cells.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

Title: Evaluation of cardiovascular complications with 99mTc tetrofosmin gated myocardial perfusion scintigraphy in patients with thalassemia major.

Journal: Revista espanola de medicina nuclear 20080101

Title: Iron chelation therapy in the myelodysplastic syndromes and aplastic anemia: a review of experience in South Korea.

Journal: International journal of hematology 20080101

Title: Efficacy of deferoxamine, N-acetylcysteine and selenium treatments in rats with Adriamycin-induced nephrotic syndrome.

Journal: Journal of nephrology 20080101

Title: A cross-sectional study of metabolic and endocrine complications in beta-thalassemia major.

Journal: Annals of Saudi medicine 20080101

Title: Anti-proliferative effect of interferon-gamma is enhanced by iron chelation in colon cancer cell lines in vitro.

Journal: Hepato-gastroenterology 20080101

Title: Ventricular arrhythmias and antioxidative medication: experimental study.

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20080101

Title: Safety and efficacy of combined chelation therapy with deferasirox and deferoxamine in a gerbil model of iron overload.

Journal: Acta haematologica 20080101

Title: Ethical issues and risk/benefit assessment of iron chelation therapy: advances with deferiprone/deferoxamine combinations and concerns about the safety, efficacy and costs of deferasirox [Kontoghiorghes GJ, Hemoglobin 2008; 32(1-2):1-15.].

Journal: Hemoglobin 20080101

Title: Transparency and access to full information for the fatal or serious toxicity risks, low efficacy and high price of deferasirox, could increase the prospect of improved iron chelation therapy worldwide.

Journal: Hemoglobin 20080101

Title: Deferoxamine therapy for intracerebral hemorrhage.

Journal: Acta neurochirurgica. Supplement 20080101

Title: Deferoxamine reduces brain swelling in a rat model of hippocampal intracerebral hemorrhage.

Journal: Acta neurochirurgica. Supplement 20080101

Title: Poly(ADP-ribose) polymerase activation and brain edema formation by hemoglobin after intracerebral hemorrhage in rats.

Journal: Acta neurochirurgica. Supplement 20080101

Title: [Hemochromatosis (hereditary, 'primary' hemochromatosis)].

Journal: Praxis 20071219

Title: Transcriptional regulation of IL-8 by iron chelator in human epithelial cells is independent from NF-kappaB but involves ERK1/2- and p38 kinase-dependent activation of AP-1.

Journal: Journal of cellular biochemistry 20071215

Title: Mutation of Streptomyces griseoflavus in order to obtain high yield desferrioxamine producing fused cells.

Journal: Pakistan journal of biological sciences : PJBS 20071215

Title: Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia.

Journal: The Journal of biological chemistry 20071214

Title: Co-expression by keratinocytes of migration stimulating factor (MSF) and a functional inhibitor of its bioactivity (MSFI).

Journal: Experimental cell research 20071210

Title: Pattern of iron chelation therapy in Egyptian beta thalassemic patients: Mansoura University Children's Hospital experience.

Journal: Hematology (Amsterdam, Netherlands) 20071201

Title: Pearson syndrome in an infant heterozygous for C282Y allele of HFE gene.

Journal: Hematology (Amsterdam, Netherlands) 20071201

Title: Oxidative stress in red blood cells, platelets and polymorphonuclear leukocytes from patients with myelodysplastic syndrome.

Journal: European journal of haematology 20071201

Title: Characterization of the ferrioxamine uptake system of Nitrosomonas europaea.

Journal: Microbiology (Reading, England) 20071201

Title: A randomized controlled 1-year study of daily deferiprone plus twice weekly desferrioxamine compared with daily deferiprone monotherapy in patients with thalassemia major.

Journal: Haematologica 20071201

Title: comparison of effects of different long-term iron-chelation regimens on myocardial and hepatic iron concentrations assessed with T2* magnetic resonance imaging in patients with beta-thalassemia major.

Journal: International journal of hematology 20071201

Title: Evaluation and management of pediatric patients with anaphylactoid reactions to deferoxamine mesylate.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20071201

Title: A widespread deferoxamine-mediated iron-uptake system in Vibrio vulnificus.

Journal: The Journal of infectious diseases 20071115

Title: Oxidative stress and metabolism in animal model of colitis induced by dextran sulfate sodium.

Journal: Journal of gastroenterology and hepatology 20071101

Title: Trafficking of siderophore transporters in Saccharomyces cerevisiae and intracellular fate of ferrioxamine B conjugates.

Journal: Traffic (Copenhagen, Denmark) 20071101

Title: Comparison of the kinetics of iron release from a marine (Trichodesmium erythraeum) Dps protein and mammalian ferritin in the presence and absence of ligands.

Journal: Journal of inorganic biochemistry 20071101

Title: Doxorubicin generates a proapoptotic phenotype by phosphorylation of elongation factor 2.

Journal: Free radical biology & medicine 20071101

Title: Inhibitory effect of 6-formylpterin on HIF-1alpha protein accumulation.

Journal: Biological & pharmaceutical bulletin 20071101

Title: Effects of desferoxamine on retinal and visual function.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20071101

Title: A low dose adrenocorticotropin test (1 microg ACTH) for the evaluation of adrenal function in children with beta-thalassemia receiving hypertransfusion with suboptimal iron-chelating therapy.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20071101

Title: Oxidative stress reduces transintestinal transports and (Na+, K+) -ATPase activity in rat jejunum.

Journal: Archives of biochemistry and biophysics 20071015

Title: Zaprinast inhibits hydrogen peroxide-induced lysosomal destabilization and cell death in astrocytes.

Journal: European journal of pharmacology 20071001

Title: Non-transferrin-bound iron reaches mitochondria by a chelator-inaccessible mechanism: biological and clinical implications.

Journal: American journal of physiology. Cell physiology 20071001

Title: Chronic hypoxia up-regulates alpha1H T-type channels and low-threshold catecholamine secretion in rat chromaffin cells.

Journal: The Journal of physiology 20071001

Title: A new family of ATP-dependent oligomerization-macrocyclization biocatalysts.

Journal: Nature chemical biology 20071001

Title: A new hippocampal model for examining intracerebral hemorrhage-related neuronal death: effects of deferoxamine on hemoglobin-induced neuronal death.

Journal: Stroke 20071001

Title: The Fe2+-mediated decomposition, PfATP6 binding, and antimalarial activities of artemisone and other artemisinins: the unlikelihood of C-centered radicals as bioactive intermediates.

Journal: ChemMedChem 20071001

Title: Clinical and economic burden of infused iron chelation therapy in the United States.

Journal: Transfusion 20071001

Title: Consequences and costs of noncompliance with iron chelation therapy in patients with transfusion-dependent thalassemia: a literature review.

Journal: Transfusion 20071001

Title: Deferoxamine synergistically enhances iron-mediated AP-1 activation: a showcase of the interplay between extracellular-signal-regulated kinase and tyrosine phosphatase.

Journal: Free radical research 20071001

Title: Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter.

Journal: Cancer research 20071001

Title: Intensive chelation therapy in beta-thalassemia and possible adverse cardiac effects of desferrioxamine.

Journal: International journal of hematology 20071001

Title: Clinical evaluation of desferrioxamine (DFO) for removal of thallium ions in rat.

Journal: The International journal of artificial organs 20071001

Title: Desferoxamine reverses neonatal iron-induced recognition memory impairment in rats.

Journal: European journal of pharmacology 20070910

Title: Adsorption behaviors of high-valence metal ions on desferrioxamine B immobilization nylon 6,6 chelate fiber under highly acidic conditions.

Journal: Journal of colloid and interface science 20070901

Title: Effect of pH and metal ions on the decomposition rate of S-nitrosocysteine.

Journal: Annals of biomedical engineering 20070901

Title: Trypanosoma cruzi: treatment with the iron chelator desferrioxamine reduces parasitemia and mortality in experimentally infected mice.

Journal: Experimental parasitology 20070901

Title: Effect of chemical stabilizers of hypoxia-inducible factors on early lung development.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070901

Title: [Hemochromatosis in the age of genetics].

Journal: Presse medicale (Paris, France : 1983) 20070901

Title: [Cardiac involvement in hemochromatosis].

Journal: Presse medicale (Paris, France : 1983) 20070901

Title: HIF stabilizing agents: shotgun or scalpel?

Journal: American journal of physiology. Lung cellular and molecular physiology 20070901

Title: Urinary iron excretion in young thalassemic patients receiving combined chelation treatment with deferoxamine and deferiprone.

Journal: Journal of pediatric hematology/oncology 20070901

Title: Antioxidant treatment prevented late memory impairment in an animal model of sepsis.

Journal: Critical care medicine 20070901

Title: Contribution of the photo-Fenton reaction to hydroxyl radical formation rates in river and rain water samples.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070901

Title: Curcumin contributes to in vitro removal of non-transferrin bound iron by deferiprone and desferrioxamine in thalassemic plasma.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20070901

Title: Coordination chemistry and biology of chelators for the treatment of iron overload disorders.

Journal: Dalton transactions (Cambridge, England : 2003) 20070814

Title: Mitochondrial superoxide production is related to the control of cytokine release from peritoneal macrophage after antioxidant treatment in septic rats.

Journal: The Journal of surgical research 20070801

Title: Phase Ib clinical trial of starch-conjugated deferoxamine (40SD02): a novel long-acting iron chelator.

Journal: British journal of haematology 20070801

Title: Diabetes mellitus concurrent with hepatic haemosiderosis in two macaws (Ara severa, Ara militaris).

Journal: Avian pathology : journal of the W.V.P.A 20070801

Title: Iron chelation, quo vadis?

Journal: Current opinion in chemical biology 20070801

Title: Light and shadows in the iron chelation treatment of haematological diseases.

Journal: British journal of haematology 20070801

Title: Current status of iron overload and chelation with deferasirox.

Journal: Indian journal of pediatrics 20070801

Title: Pediatric iron overload.

Journal: Clinical advances in hematology & oncology : H&O 20070801

Title: Oral deferiprone for iron chelation in people with thalassaemia.

Journal: The Cochrane database of systematic reviews 20070718

Title: Iron chelation and regulation of the cell cycle: 2 mechanisms of posttranscriptional regulation of the universal cyclin-dependent kinase inhibitor p21CIP1/WAF1 by iron depletion.

Journal: Blood 20070715

Title: Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool.

Journal: Free radical biology & medicine 20070715

Title: Vitamin B12b increases the cytotoxicity of short-time exposure to ascorbic acid, inducing oxidative burst and iron-dependent DNA damage.

Journal: European journal of pharmacology 20070702

Title: Expression of vascular endothelial growth factor by photodynamic therapy with mono-L-aspartyl chlorin e6 (NPe6) in oral squamous cell carcinoma.

Journal: Oral oncology 20070701

Title: Regulation of gene expression in bovine blastocysts in response to oxygen and the iron chelator desferrioxamine.

Journal: Biology of reproduction 20070701

Title: Expression and purification of catalytically active human PHD3 in Escherichia coli.

Journal: Protein expression and purification 20070701

Title: Hypoxic upregulation of glucose transporters in BeWo choriocarcinoma cells is mediated by hypoxia-inducible factor-1.

Journal: American journal of physiology. Cell physiology 20070701

Title: Free radical-mediated pre-hemolytic injury in human red blood cells subjected to lead acetate as evaluated by chemiluminescence.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070601

Title: Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2.

Journal: Cell death and differentiation 20070601

Title: Correction of anemia in a transfusion-dependent patient with primary myelofibrosis receiving iron chelation therapy with deferasirox (Exjade, ICL670).

Journal: European journal of haematology 20070601

Title: Retrospective nationwide survey of Japanese patients with transfusion-dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortality.

Journal: European journal of haematology 20070601

Title: Medical and surgical treatment of neonatal hemochromatosis: single center experience.

Journal: Pediatric transplantation 20070601

Title: Wear particles generated from studded tires and pavement induces inflammatory reactions in mouse macrophage cells.

Journal: Chemical research in toxicology 20070601

Title: Nocardichelins A and B, siderophores from Nocardia strain acta 3026.

Journal: Journal of natural products 20070601

Title: Diagnostic and therapeutic challenges.

Journal: Retina (Philadelphia, Pa.) 20070601

Title: Protein kinase Cdelta-dependent and -independent signaling in genotoxic response to treatment of desferroxamine, a hypoxia-mimetic agent.

Journal: American journal of physiology. Cell physiology 20070601

Title: Dihydroartemisinin exerts cytotoxic effects and inhibits hypoxia inducible factor-1alpha activation in C6 glioma cells.

Journal: The Journal of pharmacy and pharmacology 20070601

Title: The iron chelator deferoxamine causes activated hepatic stellate cells to become quiescent and to undergo apoptosis.

Journal: Journal of gastroenterology 20070601

Title: Low concentrations of surfactants enhance siderophore-promoted dissolution of goethite.

Journal: Environmental science & technology 20070515

Title: Iron chelation regulates cyclin D1 expression via the proteasome: a link to iron deficiency-mediated growth suppression.

Journal: Blood 20070501

Title: Signaling mechanisms of angiotensin II-induced attenuation of GABAergic input to hypothalamic presympathetic neurons.

Journal: Journal of neurophysiology 20070501

Title: Preclinical evaluation of coronary vascular function after cardioplegia with HTK and different antioxidant additives.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20070501

Title: Regulation of hepcidin in HepG2 and RINm5F cells.

Journal: Peptides 20070501

Title: Cathepsin D-Bax death pathway in oxidative stressed neuroblastoma cells.

Journal: Free radical biology & medicine 20070501

Title: Iron deprivation blocks multilineage haematopoietic differentiation by inhibiting induction of p21(WAF1/CIP1).

Journal: British journal of haematology 20070501

Title: Zinc deficiency aggravates abnormal glucose metabolism in thalassemia major patients.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20070501

Title: Liver iron concentrations and urinary hepcidin in beta-thalassemia.

Journal: Haematologica 20070501

Title: Superoxide mediated reduction of organically complexed iron(III): comparison of non-dissociative and dissociative reduction pathways.

Journal: Environmental science & technology 20070501

Title: Prospective evaluation of patient-reported outcomes during treatment with deferasirox or deferoxamine for iron overload in patients with beta-thalassemia.

Journal: Clinical therapeutics 20070501

Title: A randomized, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance.

Journal: Circulation 20070410

Title: Deferoxamine enhances anti-proliferative effect of interferon-gamma against hepatocellular carcinoma cells.

Journal: Cancer letters 20070408

Title: Cardiac hemochromatosis.

Journal: International journal of cardiology 20070404

Title: Pyridine-2,6-bis(thiocarboxylic acid) produced by Pseudomonas stutzeri KC reduces chromium(VI) and precipitates mercury, cadmium, lead and arsenic.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20070401

Title: Removal of thallium by combining desferrioxamine and deferiprone chelators in rats.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20070401

Title: Evolution of OGTT in patients with beta-thalassaemia major in relation to chelation therapy.

Journal: Diabetes research and clinical practice 20070401

Title: Iron chelation acutely stimulates fetal human intestinal cell production of IL-6 and VEGF while decreasing HGF: the roles of p38, ERK, and JNK MAPK signaling.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070401

Title: Desferrioxamine enhances hypoxic ventilatory response and induces tyrosine hydroxylase gene expression in the rat brainstem in vivo.

Journal: Journal of neuroscience research 20070401

Title: Source-dependent variation in hydroxyl radical production by airborne particulate matter.

Journal: Environmental science & technology 20070401

Title: Deferasirox.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070315

Title: Effects of combined deferiprone and desferrioxamine iron chelating therapy in beta-thalassemia major end-stage heart failure: a case report.

Journal: European journal of heart failure 20070301

Title: Crucial role of lysosomal iron in the formation of dinitrosyl iron complexes in vivo.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070301

Title: Zinc-desferrioxamine reduces damage to lenses exposed to hyperbaric oxygen and has an ameliorative effect on catalase and Na, K-ATPase activities.

Journal: Experimental eye research 20070301

Title: Deferoxamine lowers tissue damage after 80% exchange transfusion with polymerized hemoglobin.

Journal: Antioxidants & redox signaling 20070301

Title: Metal contaminants promote degradation of lipid/DNA complexes during lyophilization.

Journal: Biochimica et biophysica acta 20070301

Title: Desferrioxamine and zinc-desferrioxamine reduce lens oxidative damage.

Journal: Experimental eye research 20070301

Title: Chelation therapy for iron overload.

Journal: Current gastroenterology reports 20070301

Title: Iron studies in infants born to an iron overloaded mother with beta-thalassemia major: possible effects of maternal desferrioxamine therapy.

Journal: Journal of pediatric hematology/oncology 20070301

Title: The role of deferoxamine in the prevention of gentamicin ototoxicity: a histological and audiological study in guinea pigs.

Journal: Acta oto-laryngologica 20070301

Title: Role of the peripheral heme oxygenase-carbon monoxide pathway on the nociceptive response of rats to the formalin test: evidence for a cGMP signaling pathway.

Journal: European journal of pharmacology 20070205

Title: Complexation of Pu(IV) with the natural siderophore desferrioxamine B and the redox properties of Pu(IV)(siderophore) complexes.

Journal: Inorganic chemistry 20070205

Title: Targeting the hypoxia inducible factor pathway with mitochondrial uncouplers.

Journal: Molecular and cellular biochemistry 20070201

Title: Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species.

Journal: Journal of cellular biochemistry 20070201

Title: Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070201

Title: Alveolar macrophage cytokine response to air pollution particles: oxidant mechanisms.

Journal: Toxicology and applied pharmacology 20070201

Title: A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease.

Journal: British journal of haematology 20070201

Title: Photobleaching of retinal pigment epithelium melanosomes reduces their ability to inhibit iron-induced peroxidation of lipids.

Journal: Pigment cell research 20070201

Title: Aberrant expression of leptin in human endometriotic stromal cells is induced by elevated levels of hypoxia inducible factor-1alpha.

Journal: The American journal of pathology 20070201

Title: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene.

Journal: The FEBS journal 20070201

Title: Potential mobilization of platinum-group elements by siderophores in surface environments.

Journal: Environmental science & technology 20070201

Title: Critical role of methionine-722 in the stimulation of human brain G-proteins and neurotoxicity induced by London familial Alzheimer's disease (FAD) mutated V717G-APP(714-723).

Journal: Neuroscience 20070119

Title: Desferrioxamine (DFX) has genotoxic effects on cultured human lymphocytes and induces the p53-mediated damage response.

Journal: Toxicology 20070118

Title: Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway.

Journal: Oncogene 20070111

Title: Reversal of cardiac complications by deferiprone and deferoxamine combination therapy in a patient affected by a severe type of juvenile hemochromatosis (JH).

Journal: Blood 20070101

Title: Four-year evaluation of myocardial and liver iron assessed prospectively with serial MRI scans in young patients with beta-thalassaemia major: comparison between different chelation regimens.

Journal: European journal of haematology 20070101

Title: Peripheral blood haematopoietic progenitor cells in patients with beta thalassaemia major receiving desferrioxamine or deferiprone as chelation therapy.

Journal: European journal of haematology 20070101

Title: Histidine-induced injury to cultured liver cells, effects of histidine derivatives and of iron chelators.

Journal: Cellular and molecular life sciences : CMLS 20070101

Title: The iron- and cAMP-regulated gene SIT1 influences ferrioxamine B utilization, melanization and cell wall structure in Cryptococcus neoformans.

Journal: Microbiology (Reading, England) 20070101

Title: Down-regulation of dopamine transporter by iron chelation in vitro is mediated by altered trafficking, not synthesis.

Journal: Journal of neurochemistry 20070101

Title: Acute iron poisoning: what every pediatric intensive care unit nurse should know.

Journal: Dimensions of critical care nursing : DCCN 20070101

Title: Induction of macrophage glutamine: fructose-6-phosphate amidotransferase expression by hypoxia and by picolinic acid.

Journal: International journal of immunopathology and pharmacology 20070101

Title: Involvement of Hif-1 in desferrioxamine-induced invasion of glioblastoma cells.

Journal: Clinical & experimental metastasis 20070101

Title: Role of iron in the nitric oxide-mediated fungicidal mechanism of IFN-gamma-activated murine macrophages against Paracoccidioides brasiliensis conidia.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20070101

Title: [Prooxidant and cytotoxic action of N-acetylcysteine and glutathione combined with vitamin Bl2b].

Journal: Tsitologiia 20070101

Title: [Iron metabolism in biological systems (biochemical, pathophysiological and clinical aspects)].

Journal: Biomeditsinskaia khimiia 20070101

Title: Recent developments in iron chelation therapy.

Journal: Klinische Padiatrie 20070101

Title: Direct comparison of delta-aminolevulinic acid and methyl-aminolevulinate-derived protoporphyrin IX accumulations potentiated by desferrioxamine or the novel hydroxypyridinone iron chelator CP94 in cultured human cells.

Journal: Photochemistry and photobiology 20070101

Title: [Retinal pigment epithelium--desferal].

Journal: Bulletin de la Societe belge d'ophtalmologie 20070101

Title: 5-aminolevulinic acid-mediated photodynamic therapy on Hep-2 and MCF-7c3 cells.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101

Title: Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101

Title: Differential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-kappaB in immortalized and malignant oral keratinocytes.

Journal: BMC cancer 20070101

Title: Inhibition of spinach chloroplast F0F1 by an Fe2+/ascorbate/H2O2 system.

Journal: Plant physiology and biochemistry : PPB 20070101

Title: Lafora-like ground-glass inclusions in hepatocytes of pediatric patients: a report of two cases.

Journal: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 20070101

Title: Quality of life related to oral versus subcutaneous iron chelation: a time trade-off study.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20070101

Title: Normal lumbar bone mineral density in optimally treated children and young adolescents with beta-thalassaemia major.

Journal: Hormones (Athens, Greece) 20070101

Title: Detrimental effects of N-acetylcysteine plus desferoxamine combination in an experimental nephrotic syndrome model.

Journal: International journal of toxicology 20070101

Title: High-dose deferoxamine treatment (intravenous) for thalassaemia patients with cardiac complications.

Journal: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20070101

Title: Regulation of 5-aminolevulinic acid-dependent protoporphyrin IX accumulations in human histiocytic lymphoma U937 cells.

Journal: Physiological chemistry and physics and medical NMR 20070101

Title: Aluminum inhibits proteolytic degradation of amyloid beta peptide by cathepsin D: a potential link between aluminum accumulation and neuritic plaque deposition.

Journal: FEBS letters 20061211

Title: Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20061201

Title: Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin.

Journal: British journal of pharmacology 20061201

Title: Successful desensitization of a case with desferrioxamine hypersensitivity.

Journal: Minerva pediatrica 20061201

Title: Successful pregnancy outcome following maternal intravenous immunoglobulin treatment in a woman with recurrent perinatal haemochromatosis.

Journal: Prenatal diagnosis 20061201

Title: Huntingtin inclusion bodies are iron-dependent centers of oxidative events.

Journal: The FEBS journal 20061201

Title: Deferoxamine-related fatal nasal-orbital-cerebral mucormycosis.

Journal: Kidney international 20061201

Title: The iron-regulated transcriptome and proteome of Neisseria meningitidis serogroup C.

Journal: Proteomics 20061201

Title: Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061201

Title: Mucormycosis in a patient with low risk myelodysplasia treated with anti-TNF-alpha.

Journal: Haematologica 20061201

Title: Physical growth patterns and dental caries in thalassemia.

Journal: Indian pediatrics 20061201

Title: Deferasirox for the treatment of chronic iron overload in transfusional hemosiderosis.

Journal: Oncology (Williston Park, N.Y.) 20061201

Title: Identification of siderophores of Pseudomonas stutzeri.

Journal: Canadian journal of microbiology 20061201

Title: Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome.

Journal: The EMBO journal 20061115

Title: Iron chelators reduce chromosomal breaks in ataxia-telangiectasia cells.

Journal: DNA repair 20061108

Title: Neuroprotective effects of iron chelator Desferal on dopaminergic neurons in the substantia nigra of rats with iron-overload.

Journal: Neurochemistry international 20061101

Title: Iron overload enhances epithelial cell proliferation in endometriotic lesions induced in a murine model.

Journal: Human reproduction (Oxford, England) 20061101

Title: Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1.

Journal: Journal of cellular physiology 20061101

Title: Neisseria gonorrhoeae requires expression of TonB and the putative transporter TdfF to replicate within cervical epithelial cells.

Journal: Molecular microbiology 20061101

Title: Low levels of clustered oxidative DNA damage induced at low and high LET irradiation in mammalian cells.

Journal: Radiation and environmental biophysics 20061101

Title: Is it time to reexamine KDOQI aluminum guidelines?

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20061101

Title: Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.

Journal: Microbiology (Reading, England) 20061101

Title: Chelation therapy and bone metabolism markers in thalassemia major.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20061101

Title: Near edge X-ray absorption fine structure spectroscopy of bacterial hydroxamate siderophores in aqueous solutions.

Journal: The journal of physical chemistry. A 20061026

Title: The reactions of heme- and verdoheme-heme oxygenase-1 complexes with FMN-depleted NADPH-cytochrome P450 reductase. Electrons required for verdoheme oxidation can be transferred through a pathway not involving FMN.

Journal: The Journal of biological chemistry 20061020

Title: Molecular events contributing to cell death in malignant human hematopoietic cells elicited by an IgG3-avidin fusion protein targeting the transferrin receptor.

Journal: Blood 20061015

Title: Carbon monoxide and bilirubin from heme oxygenase-1 suppresses reactive oxygen species generation and plasminogen activator inhibitor-1 induction.

Journal: Molecular and cellular biochemistry 20061001

Title: Deferoxamine reduces tissue damage during endotoxin-induced mastitis in dairy cows.

Journal: Journal of dairy science 20061001

Title: Iron chelating in thalassaemia with left ventricular dysfunction.

Journal: Heart (British Cardiac Society) 20061001

Title: Oral iron chelators: new opportunities and new dilemmas.

Journal: Haematologica 20061001

Title: Effect of alpha-tocopherol and deferoxamine on methamphetamine-induced neurotoxicity.

Journal: Brain research 20060913

Title: p38 and ERK MAP kinase mediates iron chelator-induced apoptosis and -suppressed differentiation of immortalized and malignant human oral keratinocytes.

Journal: Life sciences 20060905

Title: Release of iron from ferritin requires lysosomal activity.

Journal: American journal of physiology. Cell physiology 20060901

Title: Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation.

Journal: American journal of physiology. Lung cellular and molecular physiology 20060901

Title: Identification of genes involved in siderophore transport in Streptomyces coelicolor A3(2).

Journal: FEMS microbiology letters 20060901

Title: Growth stimulation of Brevibacterium sp. by siderophores.

Journal: Journal of applied microbiology 20060901

Title: Survival of medically treated thalassemia patients in Cyprus. Trends and risk factors over the period 1980-2004.

Journal: Haematologica 20060901

Title: A prospective randomized controlled trial on the safety and efficacy of alternating deferoxamine and deferiprone in the treatment of iron overload in patients with thalassemia.

Journal: Haematologica 20060901

Title: Adjuvant therapy in cerebral malaria.

Journal: The Indian journal of medical research 20060901

Title: Evaluation of the resistance of blood plasma to oxidative stress by oxidizability of proteins and lipids during metal-catalyzed oxidation.

Journal: Bulletin of experimental biology and medicine 20060901

Title: Effect of enhanced iron chelation therapy on glucose metabolism in patients with beta-thalassaemia major.

Journal: British journal of haematology 20060801

Title: Survival in thalassaemia major patients.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20060801

Title: Cardiac disease in beta-thalassaemia major: Is it reversible?

Journal: Singapore medical journal 20060801

Title: Iron contributes to dopamine-induced toxicity in oligodendrocyte progenitors.

Journal: Neuropathology and applied neurobiology 20060801

Title: Cobalt induces hypoxia-inducible factor-1alpha (HIF-1alpha) in HeLa cells by an iron-independent, but ROS-, PI-3K- and MAPK-dependent mechanism.

Journal: Free radical research 20060801

Title: Deferasirox versus deferoxamine.

Journal: Blood 20060715

Title: Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in human lymphocyte death induced by nickel carbonate hydroxide in vitro.

Journal: Archives of toxicology 20060701

Title: Intralysosomal iron chelation protects against oxidative stress-induced cellular damage.

Journal: The FEBS journal 20060701

Title: Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20060701

Title: Yersinia enterocolitica ileocolitis in beta-thalassemic patients.

Journal: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20060701

Title: Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload.

Journal: Haematologica 20060701

Title: Comparative study of the protective effect between deferoxamine and deferiprone on chronic iron overload induced cardiotoxicity in rats.

Journal: Human & experimental toxicology 20060701

Title: Successful treatment of soft tissue calcifications in uremia.

Journal: Prilozi 20060701

Title: Effect of desferrioxamine, a strong iron (III) chelator, on 1-methyl-4-phenylpyridinium ion (MPP+)-induced hydroxyl radical generation in the rat striatum.

Journal: European journal of pharmacology 20060606

Title: In vitro activity of iron-binding compounds against Senegalese isolates of Plasmodium falciparum.

Journal: The Journal of antimicrobial chemotherapy 20060601

Title: Pulmonary hypertension and beta-thalassemia major: report of a case, its treatment, and a review of the literature.

Journal: American journal of hematology 20060601

Title: The effects of desferrioxamine and quercetin on hepatic ischemia-reperfusion induced renal disturbance.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20060601

Title: Severe infections in thalassaemic patients: prevalence and predisposing factors.

Journal: British journal of haematology 20060601

Title: Thoracic Surgery Directors Association Award. Cobalt chloride pretreatment attenuates myocardial apoptosis after hypothermic circulatory arrest.

Journal: The Annals of thoracic surgery 20060601

Title: The effect of metal chelators on the production of hydroxyl radicals in thylakoids.

Journal: Photosynthesis research 20060601

Title: Successful recovery of acute hemosiderotic heart failure in beta-thalassemia major treated with a combined regimen of desferrioxamine and deferiprone.

Journal: Haematologica 20060601

Title: Effective new treatments of iron overload in thalassaemia using the ICOC combination therapy protocol of deferiprone (L1) and deferoxamine and of new chelating drugs.

Journal: Haematologica 20060601

Title: Chemical characterization and quantification of siderophores produced by marine and terrestrial aspergilli.

Journal: Canadian journal of microbiology 20060601

Title: [Detection of the labile iron pool in leukemia cells and its significance].

Journal: Zhongguo shi yan xue ye xue za zhi 20060601

Title: [Deferoxamine induces apoptosis of HL-60 cells by activating caspase-3].

Journal: Zhongguo shi yan xue ye xue za zhi 20060601

Title: Common queries in thalassemia care.

Journal: Indian pediatrics 20060601

Title: Cellular iron concentrations directly affect the expression levels of norepinephrine transporter in PC12 cells and rat brain tissue.

Journal: Brain research 20060530

Title: Treatment with deferoxamine increases neurons from neural stem/progenitor cells.

Journal: Brain research 20060530

Title: c-Jun NH(2)-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells.

Journal: Cancer research 20060515

Title: A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia.

Journal: Blood 20060501

Title: Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis.

Journal: Blood 20060501

Title: Neuromelanin induces oxidative stress in mitochondria through release of iron: mechanism behind the inhibition of 26S proteasome.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20060501

Title: Cardiac morbidity and mortality in deferoxamine- or deferiprone-treated patients with thalassemia major.

Journal: Blood 20060501

Title: Combined therapy with desferrioxamine and deferiprone in beta thalassemia major patients with transfusional iron overload.

Journal: Annals of hematology 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, new questions.

Journal: Blood 20060501

Title: Iron chelator induces THP-1 cell differentiation potentially by modulating intracellular glutathione levels.

Journal: Free radical biology & medicine 20060501

Title: Therapeutic potential of iron chelators in diseases associated with iron mismanagement.

Journal: The Journal of pharmacy and pharmacology 20060501

Title: SUMOylation attenuates sensitivity toward hypoxia- or desferroxamine-induced injury by modulating adaptive responses in salivary epithelial cells.

Journal: The American journal of pathology 20060501

Title: Exchange blood transfusions for the treatment of leg ulcerations in thalassemia intermedia.

Journal: Haematologica 20060501

Title: A case of rhesus hemolytic disease with hemophagocytosis and severe iron overload due to multiple transfusions.

Journal: Journal of pediatric hematology/oncology 20060501

Title: Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway.

Journal: Biochemical and biophysical research communications 20060428

Title: Reversible inhibition of caspase-3 activity by iron(III): potential role in physiological control of apoptosis.

Journal: FEBS letters 20060417

Title: Phosphorylation and activation of STAT proteins by hypoxia in breast cancer cells.

Journal: Breast (Edinburgh, Scotland) 20060401

Title: Oxygen tension modulates the expression of pulmonary vascular BKCa channel alpha- and beta-subunits.

Journal: American journal of physiology. Lung cellular and molecular physiology 20060401

Title: Iron chelator-induced growth arrest and cytochrome c-dependent apoptosis in immortalized and malignant oral keratinocytes.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20060401

Title: Reduction of iron-regulated amyloid precursor protein and beta-amyloid peptide by (-)-epigallocatechin-3-gallate in cell cultures: implications for iron chelation in Alzheimer's disease.

Journal: Journal of neurochemistry 20060401

Title: Iron: not a benign therapeutic drug.

Journal: Current opinion in pediatrics 20060401

Title: Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.

Journal: The European journal of neuroscience 20060401

Title: Ternary complex formation facilitates a redox mechanism for iron release from a siderophore.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20060401

Title: Impact of long-term iron chelation therapy on growth and endocrine functions in thalassaemia.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20060401

Title: Rate of iron transfer through the horse spleen ferritin shell determined by the rate of formation of Prussian Blue and Fe-desferrioxamine within the ferritin cavity.

Journal: Biophysical chemistry 20060320

Title: Aluminum toxicity due to intravenous injection of boiled methadone.

Journal: The New England journal of medicine 20060316

Title: Heme-oxygenase-1 promotes polychlorinated biphenyl mixture aroclor 1254-induced oxidative stress and dopaminergic cell injury.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060301

Title: Acute depletion of reduced glutathione causes extensive carbonylation of rat brain proteins.

Journal: Journal of neuroscience research 20060301

Title: Evaluation of the efficacy of oral deferiprone in beta-thalassemia major by multislice multiecho T2*.

Journal: European journal of haematology 20060301

Title: Intramuscular deferoxamine in hereditary hemochromatosis.

Journal: American journal of hematology 20060301

Title: New chelation therapies and emerging chelating drugs for the treatment of iron overload.

Journal: Expert opinion on emerging drugs 20060301

Title: Oxidative stress and autologous immunoglobulin G binding to band 3 dimers in newborn erythrocytes.

Journal: Free radical biology & medicine 20060301

Title: Candida albicans can utilize siderophore during candidastasis caused by apotransferrin.

Journal: Archives of pharmacal research 20060301

Title: Weekend very high-dose intravenous deferoxamine in children with transfusional iron overload.

Journal: Journal of pediatric hematology/oncology 20060301

Title: Thermospectroscopic study of the adsorption mechanism of the hydroxamic siderophore ferrioxamine B by calcium montmorillonite.

Journal: Journal of agricultural and food chemistry 20060222

Title: Protective effects of resveratrol against oxidative/nitrative modifications of plasma proteins and lipids exposed to peroxynitrite.

Journal: The Journal of nutritional biochemistry 20060201

Title: Differential responses of two degradation domains of HIF-1alpha to hypoxia and iron deficiency.

Journal: Biochimie 20060201

Title: In vivo fragmentation of the large subunit of ribulose-1,5-bisphosphate carboxylase by reactive oxygen species in an intact leaf of cucumber under chilling-light conditions.

Journal: Plant & cell physiology 20060201

Title: Rapid development of severe toxic retinopathy associated with continuous intravenous deferoxamine infusion.

Journal: The British journal of ophthalmology 20060201

Title: Effects of N-acetylcysteine plus deferoxamine in lipopolysaccharide-induced acute lung injury in the rat.

Journal: Critical care medicine 20060201

Title: More antioxidants in sepsis: still paved with uncertainties.

Journal: Critical care medicine 20060201

Title: Long-term effects of experimental intracerebral hemorrhage: the role of iron.

Journal: Journal of neurosurgery 20060201

Title: Iron chelators: correlation between effects on Plasmodium spp. and immune functions.

Journal: The Journal of parasitology 20060201

Title: Effect of neonatal body temperature on postanoxic, potentially neurotoxic iron accumulation in the rat brain.

Journal: Neuroscience letters 20060130

Title: Prooxidative effect of copper--metallothionein in the acute cytotoxicity of hydrogen peroxide in Ehrlich ascites tumour cells.

Journal: Toxicology 20060116

Title: Neurophysiologic and intellectual evaluation of beta-thalassemia patients.

Journal: Brain & development 20060101

Title: fMLP-stimulated release of reactive oxygen species from adherent leukocytes increases microvessel permeability.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma.

Journal: Gynecologic oncology 20060101

Title: Design, synthesis and in vitro antimalarial activity of an acylhydrazone library.

Journal: Bioorganic & medicinal chemistry letters 20060101

Title: Cold-induced injury to porcine corneal endothelial cells and its mediation by chelatable iron: implications for corneal preservation.

Journal: Cornea 20060101

Title: Tandem mass spectrometry of coprogen and deferoxamine hydroxamic siderophores.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Hypoxia-mimetic agents desferrioxamine and cobalt chloride induce leukemic cell apoptosis through different hypoxia-inducible factor-1alpha independent mechanisms.

Journal: Apoptosis : an international journal on programmed cell death 20060101

Title: Iron chelation treatment with combined therapy with deferiprone and deferioxamine: a 12-month trial.

Journal: Blood cells, molecules & diseases 20060101

Title: Subcutaneous bolus injection of deferoxamine is an alternative method to subcutaneous continuous infusion.

Journal: Journal of pediatric hematology/oncology 20060101

Title: Myelodysplastic syndromes: iron overload consequences and current chelating therapies.

Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20060101

Title: Development of thalassaemic iron overload cardiomyopathy despite low liver iron levels and meticulous compliance to desferrioxamine.

Journal: Acta haematologica 20060101

Title: [Magnetic resonance imaging evidence of the effectiveness of combination chelation therapy in iron overload cardiomyopathy].

Journal: Revista espanola de cardiologia 20060101

Title: Solid-phase synthesis of biologically interesting compounds containing hydroxamic acid moiety.

Journal: Mini reviews in medicinal chemistry 20060101

Title: Deferiprone or deferoxamine vs. combination therapy in patients with beta-thalassemia major: a case study in Taiwan.

Journal: Hemoglobin 20060101

Title: Iron burden and liver fibrosis decrease during a long-term phlebotomy program and iron chelating treatment after bone marrow transplantation.

Journal: Hemoglobin 20060101

Title: The effects of desferrioxamine and quercetin on liver injury induced by hepatic ischaemia-reperfusion in rats.

Journal: Acta chirurgica Belgica 20060101

Title: Deferoxamine reduces CSF free iron levels following intracerebral hemorrhage.

Journal: Acta neurochirurgica. Supplement 20060101

Title: Coenzyme Q(10) provides neuroprotection in iron-induced apoptosis in dopaminergic neurons.

Journal: Journal of molecular neuroscience : MN 20060101

Title: Influence of human haptoglobin polymorphism on oxidative stress induced by free hemoglobin on red blood cells.

Journal: Clinical chemistry and laboratory medicine 20060101

Title: Reactive oxygen species generation in gingival fibroblasts of Down syndrome patients detected by electron spin resonance spectroscopy.

Journal: Redox report : communications in free radical research 20060101

Title: Novel trihydroxamate-containing peptides: design, synthesis, and metal coordination.

Journal: Biopolymers 20060101

Title: Aluminum toxicity following IV use of oral methadone solution.

Journal: Clinical toxicology (Philadelphia, Pa.) 20060101

Title: Myocardial iron loading in patients with thalassemia major on deferoxamine chelation.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20060101

Title: Liver fibrosis and iron levels during long-term deferiprone treatment of thalassemia major patients.

Journal: Hemoglobin 20060101

Title: Low serum ferritin levels are misleading for detecting cardiac iron overload and increase the risk of cardiomyopathy in thalassemia patients. The importance of cardiac iron overload monitoring using magnetic resonance imaging T2 and T2*.

Journal: Hemoglobin 20060101

Title: Regression of myocardial dysfunction after switching from desferrioxamine to deferiprone therapy in beta-thalassemia major patients.

Journal: Hemoglobin 20060101

Title: Effective combination therapy of deferiprone and deferoxamine for the rapid clearance of excess cardiac IRON and the prevention of heart disease in thalassemia. The Protocol of the International Committee on Oral Chelators.

Journal: Hemoglobin 20060101

Title: Glutathione S-transferase M1 gene polymorphisms are associated with cardiac iron deposition in patients with beta-thalassemia major.

Journal: Hemoglobin 20060101

Title: Comparison of oral and subcutaneous iron chelation therapies in the prevention of major endocrinopathies in beta-thalassemia major patients.

Journal: Hemoglobin 20060101

Title: A randomized controlled study evaluating the safety and efficacy of deferiprone treatment in thalassemia major patients from Hong Kong.

Journal: Hemoglobin 20060101

Title: Thalassemia treatment and prevention in Uva Province, Sri Lanka: a public opinion survey.

Journal: Hemoglobin 20060101

Title: Pilot study on the 'quality of life' as reflected by psychosocial adjustment of children with thalassemia major undergoing iron-chelating treatment in western Taiwan.

Journal: Hemoglobin 20060101

Title: Pilot study on parental stress and behavioral adjustment to the thalassemia major disease process in children undergoing iron-chelation in western Taiwan.

Journal: Hemoglobin 20060101

Title: Future chelation monotherapy and combination therapy strategies in thalassemia and other conditions. comparison of deferiprone, deferoxamine, ICL670, GT56-252, L1NAll and starch deferoxamine polymers.

Journal: Hemoglobin 20060101

Title: Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis.

Journal: Arthritis research & therapy 20060101

Title: The impact of iron overload and its treatment on quality of life: results from a literature review.

Journal: Health and quality of life outcomes 20060101

Title: Peripheral neuropathy in thalassaemia.

Journal: Annals of Saudi medicine 20060101

Title: Endothelial cell preservation at 10 degrees C minimizes catalytic iron, oxidative stress, and cold-induced injury.

Journal: Cell transplantation 20060101

Title: New advances in iron chelation therapy.

Journal: Hematology. American Society of Hematology. Education Program 20060101

Title: Yeast flavohemoglobin protects against nitrosative stress and controls ferric reductase activity.

Journal: Redox report : communications in free radical research 20060101

Title: Iron chelator deferoxamine induces epithelial transformation of tumor cells.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20060101

Title: Novel neuroprotective neurotrophic NAP analogs targeting metal toxicity and oxidative stress: potential candidates for the control of neurodegenerative diseases.

Journal: Journal of neural transmission. Supplementum 20060101

Title: Metal specificity of an iron-responsive element in Alzheimer's APP mRNA 5'untranslated region, tolerance of SH-SY5Y and H4 neural cells to desferrioxamine, clioquinol, VK-28, and a piperazine chelator.

Journal: Journal of neural transmission. Supplementum 20060101

Title: [Clinical findings and therapy of classical hereditary haemochromatosis (type 1)].

Journal: Deutsche medizinische Wochenschrift (1946) 20051216

Title: Molecular genetics of Erwinia amylovora involved in the development of fire blight.

Journal: FEMS microbiology letters 20051215

Title: Dermatan carriers for neovascular transport targeting, deep tumor penetration and improved therapy.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20051205

Title: Desferrioxamine release from gelatin-based systems.

Journal: Biotechnology and applied biochemistry 20051201

Title: Iron loading inhibits ferroportin1 expression in PC12 cells.

Journal: Neurochemistry international 20051201

Title: Oxygen-dependent modulation of insulin-like growth factor binding protein biosynthesis in primary cultures of rat hepatocytes.

Journal: Endocrinology 20051201

Title: Antioxidants to prevent bovine neutrophil-induced mammary epithelial cell damage.

Journal: Journal of dairy science 20051201

Title: The effect of superoxide anion on autoregulation of cerebral blood flow.

Journal: Stroke 20051201

Title: Hypoxia-simulating agents selectively stimulate arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells.

Journal: Haematologica 20051201

Title: Expression of alternative transcripts of ferroportin-1 during human erythroid differentiation.

Journal: Haematologica 20051201

Title: Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells.

Journal: Haematologica 20051201

Title: Auditory and visual toxicity during deferoxamine therapy in transfusion-dependent patients.

Journal: Journal of pediatric hematology/oncology 20051201

Title: Iron-dependent lysosomal destabilization initiates silica-induced apoptosis in murine macrophages.

Journal: Toxicology letters 20051115

Title: Thorium complexation by hydroxamate siderophores in perturbed multicomponent systems using flow injection electrospray ionization mass spectrometry.

Journal: Analytical chemistry 20051115

Title: Intracellular labile iron pools as direct targets of iron chelators: a fluorescence study of chelator action in living cells.

Journal: Blood 20051101

Title: Iron chelation suppresses ferritin upregulation and attenuates vascular dysfunction in the aorta of angiotensin II-infused rats.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20051101

Title: Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells.

Journal: Endocrinology 20051101

Title: Novel diaroylhydrazine ligands as iron chelators: coordination chemistry and biological activity.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20051101

Title: Lipid accumulation and transforming growth factor-beta upregulation in the kidneys of rats administered angiotensin II.

Journal: Hypertension (Dallas, Tex. : 1979) 20051101

Title: Iron and insulin resistance.

Journal: Alimentary pharmacology & therapeutics 20051101

Title: Atypical L-type channels are down-regulated in hypoxia.

Journal: Biochemical Society transactions 20051101

Title: A review of the quality of randomized clinical trials of adjunctive therapy for the treatment of cerebral malaria.

Journal: Tropical medicine & international health : TM & IH 20051101

Title: N-acetylcysteine and deferoxamine reduce pulmonary oxidative stress and inflammation in rats after coal dust exposure.

Journal: Environmental research 20051101

Title: Desferrioxamine mesylate for managing transfusional iron overload in people with transfusion-dependent thalassaemia.

Journal: The Cochrane database of systematic reviews 20051019

Title: Nickel compound-induced DNA single-strand breaks in chromosomal and nuclear chromatin in human blood lymphocytes in vitro: role of oxidative stress and intracellular calcium.

Journal: Mutation research 20051003

Title: Extent of iron pick-up in deforoxamine-coupled polyurethane materials for therapy of chronic wounds.

Journal: Biomaterials 20051001

Title: Involvement of oxygen free radicals in the serum-mediated increase of benzoquinone genotoxicity.

Journal: Environmental and molecular mutagenesis 20051001

Title: Hypoxia-inducible factor 1alpha and erythropoietin upregulation with deferoxamine salvage after neonatal stroke.

Journal: Experimental neurology 20051001

Title: Recent acquisitions in the management of iron overload.

Journal: Annals of hematology 20051001

Title: Foam cell death induced by 7beta-hydroxycholesterol is mediated by labile iron-driven oxidative injury: mechanisms underlying induction of ferritin in human atheroma.

Journal: Free radical biology & medicine 20051001

Title: Transfusional hemosiderosis and combined chelation therapy in sickle thalassemia.

Journal: European journal of haematology 20051001

Title: Air pollution particles activate NF-kappaB on contact with airway epithelial cell surfaces.

Journal: Toxicology and applied pharmacology 20051001

Title: Variability of biological effects of silicas: different degrees of activation of the fifth component of complement by amorphous silicas.

Journal: Toxicology and applied pharmacology 20051001

Title: Combined therapy with deferiprone and desferrioxamine in thalassemia major.

Journal: Haematologica 20051001

Title: Combined therapy with deferiprone and desferrioxamine in thalassemia major.

Journal: Haematologica 20051001

Title: Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in nickel sulfate-induced human lymphocyte death in vitro.

Journal: Chemico-biological interactions 20050910

Title: Perinatal asphyxia, hyperthermia and hyperferremia as factors inducing behavioural disturbances in adulthood: a rat model.

Journal: Behavioural brain research 20050908

Title: Validated HPLC assay for iron determination in biological matrices based on ferrioxamine formation.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050905

Title: Hypoxia-induced IL-6 production is associated with activation of MAP kinase, HIF-1, and NF-kappaB on HEI-OC1 cells.

Journal: Hearing research 20050901

Title: Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures.

Journal: International journal of oncology 20050901

Title: Desferrioxamine E produced by Streptomyces griseus stimulates growth and development of Streptomyces tanashiensis.

Journal: Microbiology (Reading, England) 20050901

Title: Iron chelator induces MIP-alpha/CCL20 in human intestinal epithelial cells: implication for triggering mucosal adaptive immunity.

Journal: Experimental & molecular medicine 20050831

Title: Hypoxia activates the cyclin D1 promoter via the Jak2/STAT5b pathway in breast cancer cells.

Journal: Experimental & molecular medicine 20050831

Title: [Research progress on iron chelator for malaria therapy].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20050830

Title: Siderophore-manganese(III) interactions. I. Air-oxidation of manganese(ll) promoted by desferrioxamine B.

Journal: Environmental science & technology 20050815

Title: Siderophore-manganese(lll) Interactions. II. Manganite dissolution promoted by desferrioxamine B.

Journal: Environmental science & technology 20050815

Title: Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells.

Journal: Physiological genomics 20050811

Title: Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801

Title: Cytotoxicity and gene induction by some essential oils in the yeast Saccharomyces cerevisiae.

Journal: Mutation research 20050801

Title: Aluminum-triggered structural modifications and aggregation of beta-amyloids.

Journal: Cellular and molecular life sciences : CMLS 20050801

Title: p66(shc) is highly expressed in fibroblasts from centenarians.

Journal: Mechanisms of ageing and development 20050801

Title: Desferal inhibits breast tumor growth and does not interfere with the tumoricidal activity of doxorubicin.

Journal: Free radical biology & medicine 20050801

Title: Hepatocellular damage following therapeutic intravenous iron sucrose infusion in a child.

Journal: Therapeutic drug monitoring 20050801

Title: Iron and iron chelating agents modulate Mycobacterium tuberculosis growth and monocyte-macrophage viability and effector functions.

Journal: FEMS immunology and medical microbiology 20050801

Title: Bacterial siderophores promote dissolution of UO2 under reducing conditions.

Journal: Environmental science & technology 20050801

Title: Intracellular free iron and acidic pathways mediate TNF-induced death of rat hepatoma cells.

Journal: Apoptosis : an international journal on programmed cell death 20050801

Title: The ABC transporter Abcg2/Bcrp: role in hypoxia mediated survival.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20050801

Title: Antioxidative effect of vitamin D3 on zinc-induced oxidative stress in CNS.

Journal: Annals of the New York Academy of Sciences 20050801

Title: Neuroprotection by iron chelator against proteasome inhibitor-induced nigral degeneration.

Journal: Biochemical and biophysical research communications 20050729

Title: Metavanadate suppresses desferrioxamine-induced leukemic cell differentiation with reduced hypoxia-inducible factor-1alpha protein.

Journal: Biochemical and biophysical research communications 20050715

Title: Desferrioxamine induces leukemic cell differentiation potentially by hypoxia-inducible factor-1 alpha that augments transcriptional activity of CCAAT/enhancer-binding protein-alpha.

Journal: Leukemia 20050701

Title: Deferoxamine photosensitizes cancer cells in vitro.

Journal: Biochemical and biophysical research communications 20050701

Title: Deferoxamine as a chelator for 67Ga in the preparation of antibody conjugates.

Journal: Nuclear medicine and biology 20050701

Title: Apoptosis vs. necrosis: glutathione-mediated cell death during rewarming of rat hepatocytes.

Journal: Biochimica et biophysica acta 20050610

Title: Iron-chelating therapy with the new oral agent ICL670 (Exjade).

Journal: Best practice & research. Clinical haematology 20050601

Title: Endothelial cell NADPH oxidase mediates the cerebral microvascular dysfunction in sickle cell transgenic mice.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050601

Title: Non-transferrin-bound iron in platelet concentrates promotes the growth of Staphylococcus epidermidis.

Journal: Transfusion 20050601

Title: Desferrioxamine inhibits production of cytotoxic heme to protein cross-linked myoglobin: a mechanism to protect against oxidative stress without iron chelation.

Journal: Chemical research in toxicology 20050601

Title: Effects of extracellular iron concentration on calcium absorption and relationship between Ca2+ and cell apoptosis in Caco-2 cells.

Journal: World journal of gastroenterology 20050521

Title: Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.

Journal: Experimental cell research 20050515

Title: [Study of deferoxamine in subcutaneous profusion treatment of iron overload in myelodysplastic syndromes].

Journal: Medicina clinica 20050507

Title: A role for hypoxia-inducible factor-1alpha in desferoxamine neuroprotection.

Journal: Neuroscience letters 20050506

Title: Thermo-FTIR spectroscopic study of the siderophore ferrioxamine B: spectral analysis and stereochemical implications of iron chelation, pH, and temperature.

Journal: Journal of agricultural and food chemistry 20050504

Title: Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis.

Journal: The Biochemical journal 20050501

Title: Barriers to adherence of deferoxamine usage in sickle cell disease.

Journal: Pediatric blood & cancer 20050501

Title: Role of iron in inactivation of epidermal growth factor receptor after asbestos treatment of human lung and pleural target cells.

Journal: American journal of respiratory cell and molecular biology 20050501

Title: The iron chelator desferrioxamine inhibits atherosclerotic lesion development and decreases lesion iron concentrations in the cholesterol-fed rabbit.

Journal: Free radical biology & medicine 20050501

Title: Induction of hypoxia inducible factor-1 attenuates metabolic insults induced by 3-nitropropionic acid in rat C6 glioma cells.

Journal: Journal of neurochemistry 20050501

Title: Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells.

Journal: American journal of physiology. Cell physiology 20050501

Title: Treatment of ocular tissues exposed to nitrogen mustard: beneficial effect of zinc desferrioxamine combined with steroids.

Journal: Investigative ophthalmology & visual science 20050501

Title: Impairment of cardiac function in a successful full-term pregnancy in a homozygous beta-thalassemia major: does chelation have a positive role?

Journal: European journal of obstetrics, gynecology, and reproductive biology 20050501

Title: Post-transcriptional regulation of plasminogen activator inhibitor-1 by intracellular iron in cultured human lung fibroblasts--interaction of an 81-kDa nuclear protein with the 3'-UTR.

Journal: Journal of thrombosis and haemostasis : JTH 20050501

Title: Moderation of morphogenetic and oxidative stress responses in flax in vitro cultures by hydroxynonenal and desferrioxamine.

Journal: Journal of plant physiology 20050501

Title: Virus-based reporter systems for monitoring transcriptional activity of hypoxia-inducible factor 1.

Journal: Gene 20050425

Title: Reduction of organically complexed ferric iron by superoxide in a simulated natural water.

Journal: Environmental science & technology 20050415

Title: Iron chelation and a free radical scavenger suppress angiotensin II-induced upregulation of TGF-beta1 in the heart.

Journal: American journal of physiology. Heart and circulatory physiology 20050401

Title: A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases.

Journal: Chembiochem : a European journal of chemical biology 20050401

Title: Monitoring and treatment of iron overload: state of the art and new approaches.

Journal: Seminars in hematology 20050401

Title: Overcoming the challenge of patient compliance with iron chelation therapy.

Journal: Seminars in hematology 20050401

Title: Treating iron overload: the state of the art.

Journal: Seminars in hematology 20050401

Title: Enhanced toxicity to the catecholamine tyramine in polyglutamine transfected SH-SY5Y cells.

Journal: Neurochemical research 20050401

Title: Haptoglobin genotype- and diabetes-dependent differences in iron-mediated oxidative stress in vitro and in vivo.

Journal: Circulation research 20050304

Title: Sed1p interacts with Arn3p physically and mediates ferrioxamine B uptake in Saccharomyces cerevisiae.

Journal: Current genetics 20050301

Title: Tyrosine nitration on p65: a novel mechanism to rapidly inactivate nuclear factor-kappaB.

Journal: Molecular & cellular proteomics : MCP 20050301

Title: Different cytoprotective effect of antioxidants and change in the iron regulatory system in rodent cells exposed to paraquat or formaldehyde.

Journal: Toxicology 20050301

Title: Iron chelation therapy.

Journal: Current hematology reports 20050301

Title: Lack of prognostic value of normalized integrated backscatter analysis of myocardium in patients with thalassemia major: a long-term follow-up study.

Journal: Echocardiography (Mount Kisco, N.Y.) 20050301

Title: Therapy of porphyria cutanea tarda.

Journal: Expert opinion on pharmacotherapy 20050301

Title: Deferasirox Novartis.

Journal: Current opinion in investigational drugs (London, England : 2000) 20050301

Title: Acute respiratory distress syndrome due to overdose desferrioxamine: report of a child.

Journal: The Medical journal of Malaysia 20050301

Title: Changed iron regulation in scrapie-infected neuroblastoma cells.

Journal: Brain research. Molecular brain research 20050218

Title: Synergistic production of lung free radicals by diesel exhaust particles and endotoxin.

Journal: American journal of respiratory and critical care medicine 20050215

Title: Novel function of neuronal PAS domain protein 1 in erythropoietin expression in neuronal cells.

Journal: Journal of neuroscience research 20050215

Title: Ferrioxamine B analogues: targeting the FoxA uptake system in the pathogenic Yersinia enterocolitica.

Journal: Journal of the American Chemical Society 20050202

Title: Stimulation of G-proteins in human control and Alzheimer's disease brain by FAD mutants of APP(714-723): implication of oxidative mechanisms.

Journal: Journal of neuroscience research 20050201

Title: Deferoxamine infusion during coronary artery bypass grafting ameliorates lipid peroxidation and protects the myocardium against reperfusion injury: immediate and long-term significance.

Journal: European heart journal 20050201

Title: Serum ferritin level as a predictor of impaired growth and puberty in thalassemia major patients.

Journal: European journal of haematology 20050201

Title: Psychosocial implications of Thalassemia Major.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20050201

Title: Emla cream-induced allergic contact dermatitis in a child with thalassaemia major.

Journal: Contact dermatitis 20050201

Title: Acute liver failure due to iron overdose in an adult.

Journal: Southern medical journal 20050201

Title: Essential role of singlet oxygen species in cytochrome P450-dependent substrate oxygenation by rat liver microsomes.

Journal: Drug metabolism and pharmacokinetics 20050201

Title: Baroreflex function in conscious rats submitted to iron overload.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20050201

Title: The determination of ferric iron in plants by HPLC using the microbial iron chelator desferrioxamine E.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20050201

Title: Platelet-activating factor enhances the expression of nerve growth factor in normal human astrocytes under hypoxia.

Journal: Brain research. Molecular brain research 20050105

Title: Genome-wide screen for genes with effects on distinct iron uptake activities in Saccharomyces cerevisiae.

Journal: Genetics 20050101

Title: Successful transplantation of CD34+ selected peripheral blood stem cells from an unrelated donor in an adult patient with Diamond-Blackfan anemia and secondary hemochromatosis.

Journal: Bone marrow transplantation 20050101

Title: Deferoxamine induces prolonged cardiac preconditioning via accumulation of oxygen radicals.

Journal: Free radical biology & medicine 20050101

Title: Characterization of clinically isolated Ralstonia mannitolilytica strains using random amplification of polymorphic DNA (RAPD) typing and antimicrobial sensitivity, and comparison of the classification efficacy of phenotypic and genotypic assays.

Journal: Journal of medical microbiology 20050101

Title: Reversal of heart failure in thalassemia major by combined chelation therapy: a case report.

Journal: European journal of haematology 20050101

Title: Combination treatment of vitamin C and desferrioxamine suppresses glomerular superoxide and prostaglandin E production in diabetic rats.

Journal: Diabetes, obesity & metabolism 20050101

Title: Liver iron concentration and fibrosis in a cohort of transfusion-dependent patients on long-term desferrioxamine therapy.

Journal: The hematology journal : the official journal of the European Haematology Association 20050101

Title: Ischaemic preconditioning but not isoflurane prevents post-ischaemic production of hydroxyl radicals in a canine model of ischaemia-reperfusion.

Journal: European journal of anaesthesiology 20050101

Title: Intensification of chelating-therapy in patients with thalassemia major.

Journal: Klinische Padiatrie 20050101

Title: Ocular abnormalities associated with advanced kidney disease and hemodialysis.

Journal: Seminars in dialysis 20050101

Title: Iron-mediated stability of PAI-1 mRNA in adenocarcinoma cells-involvement of a mRNA-binding nuclear protein.

Journal: Thrombosis research 20050101

Title: Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine in HepG2 cells.

Journal: Drug metabolism and drug interactions 20050101

Title: Combined use of oral chelators and desferrioxamine in thalassemia.

Journal: Hematology (Amsterdam, Netherlands) 20050101

Title: Inhibitory effect of deferoxamine on Paracoccidioides brasiliensis survival in human monocytes: reversal by holotransferrin not by apotransferrin.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20050101

Title: Advances in iron overload therapies. prospects for effective use of deferiprone (L1), deferoxamine, the new experimental chelators ICL670, GT56-252, L1NA11 and their combinations.

Journal: Current medicinal chemistry 20050101

Title: Molecular factors and mechanisms affecting iron and other metal excretion or absorption in health and disease: the role of natural and synthetic chelators.

Journal: Current medicinal chemistry 20050101

Title: Role of iron-ATP complex in lymphocyte proliferation and infiltration.

Journal: Biological trace element research 20050101

Title: Objectives and mechanism of iron chelation therapy.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Recent insights into interactions of deferoxamine with cellular and plasma iron pools: Implications for clinical use.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Deferiprone: New insight.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Combined therapy with deferoxamine and deferiprone.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Bone marrow transplantation in adults with thalassemia: Treatment and long-term follow-up.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Quality of life in thalassemia.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Monitoring long-term efficacy of iron chelation treatment with biomagnetic liver susceptometry.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Methods for noninvasive measurement of tissue iron in Cooley's anemia.

Journal: Annals of the New York Academy of Sciences 20050101

Title: T2* magnetic resonance and myocardial iron in thalassemia.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Non-transferrin-bound iron during blood transfusion cycles in beta-thalassemia major.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Low bone mineral density in adolescents with beta-thalassemia.

Journal: Annals of the New York Academy of Sciences 20050101

Title: A simple model to assess and improve adherence to iron chelation therapy with deferoxamine in patients with thalassemia.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Management of the 'difficult' iron-overloaded patient.

Journal: Annals of the New York Academy of Sciences 20050101

Title: Effect of Danchunwhangagam on LPS or DFX-induced cytokine production in peripheral mononuclear cells of cerebral infarction patients.

Journal: Immunopharmacology and immunotoxicology 20050101

Title: Identification of a cluster of genes that directs desferrioxamine biosynthesis in Streptomyces coelicolor M145.

Journal: Journal of the American Chemical Society 20041222

Title: 6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia.

Journal: The Journal of biological chemistry 20041217

Title: [Therapy for ROD and measurement of the bone mass].

Journal: Clinical calcium 20041201

Title: The integrated role of desferrioxamine and phenserine targeted to an iron-responsive element in the APP-mRNA 5'-untranslated region.

Journal: Annals of the New York Academy of Sciences 20041201

Title: Reduced insulin growth factor I concentrations in iron-overloaded beta thalassaemic patients with normal growth hormone secretion and liver function.

Journal: Pediatric endocrinology reviews : PER 20041201

Title: Glucose metabolism disorders improvement in patients with thalassaemia major after 24-36 months of intensive chelation therapy.

Journal: Pediatric endocrinology reviews : PER 20041201

Title: Cardiac status in well-treated patients with thalassemia major.

Journal: European journal of haematology 20041101

Title: Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance.

Journal: British journal of haematology 20041101

Title: Clustering of death receptors in lipid rafts initiates neutrophil spontaneous apoptosis.

Journal: Biochemical Society transactions 20041101

Title: Do the serum oxidative stress biomarkers provide a reasonable index of the general oxidative stress status?

Journal: Biochimica et biophysica acta 20041101

Title: The role of nitric oxide in iron-induced rat renal injury.

Journal: Human & experimental toxicology 20041101

Title: [Putative mechanism of experimental immunological liver injury and influence of iron low-load on the injury in rat].

Journal: Wei sheng yan jiu = Journal of hygiene research 20041101

Title: EOG as a monitor of desferrioxamine retinal toxicity.

Journal: Documenta ophthalmologica. Advances in ophthalmology 20041101

Title: Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation.

Journal: FEBS letters 20041008

Title: Stress-induced behaviour in juvenile rats: effects of neonatal asphyxia, body temperature and chelation of iron.

Journal: Behavioural brain research 20041005

Title: REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20041001

Title: Susceptibility of skin cells to UVA-induced necrotic cell death reflects the intracellular level of labile iron.

Journal: The Journal of investigative dermatology 20041001

Title: Possible involvement of pyruvate kinase in acquisition of tolerance to hypoxic stress in glial cells.

Journal: Journal of neurochemistry 20041001

Title: Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine.

Journal: Haematologica 20041001

Title: Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats.

Journal: Critical care medicine 20041001

Title: Secretion of ferritin by iron-laden macrophages and influence of lipoproteins.

Journal: Free radical research 20041001

Title: Modulation of iron on mitochondrial aconitase expression in human prostatic carcinoma cells.

Journal: Molecular and cellular biochemistry 20041001

Title: [Effect of combination of Ginkgo leaf extract and deferoxamine in preventing and treating ototoxicity of cisplatin].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20041001

Title: The utility of multifocal electroretinography in monitoring drug toxicity: deferoxamine retinopathy.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20041001

Title: Synthesis and biological evaluation of new acinetoferrin homologues for use as iron transport probes in mycobacteria.

Journal: Journal of medicinal chemistry 20040923

Title: Does oxidative stress contribute in tricyclic antidepressants-induced cardiotoxicity?

Journal: Toxicology letters 20040910

Title: Effects of iron deprivation or chelation on DNA damage in experimental colitis.

Journal: International journal of colorectal disease 20040901

Title: Mechanism of in vitro heme-induced LDL oxidation: effects of antioxidants.

Journal: European journal of clinical investigation 20040901

Title: [Comparison of the effects of colloid and crystalloid solution for volume preloading on maternal hemodynamics and neonatal outcome in spinal anesthesia for cesarean section].

Journal: Masui. The Japanese journal of anesthesiology 20040901

Title: The glutathione reductase inhibitor carmustine induces an influx of Ca2+ in PC12 cells.

Journal: European journal of pharmacology 20040816

Title: New approach for bone marrow transplantation in patients with class 3 thalassemia aged younger than 17 years.

Journal: Blood 20040815

Title: Severe hemolytic anemia associated with Hb Volga [beta27(B9)Ala-->Asp]: GCC-->GAC at codon 27 in a Turkish family.

Journal: American journal of hematology 20040801

Title: Desferrioxamine related maculopathy: a case report.

Journal: American journal of hematology 20040801

Title: Comparison of subcutaneous infusion needles for transfusion-dependent thalassemia patients by the intrapersonal cross-over assessment model.

Journal: American journal of hematology 20040801

Title: Adherence to deferoxamine therapy: heeding Hippocrates and Osler.

Journal: American journal of hematology 20040801

Title: Is growth hormone deficiency contributing to heart failure in patients with beta-thalassemia major?

Journal: European journal of endocrinology 20040801

Title: Photooxidation and its effects on the carboxyl content of dissolved organic matter in two coastal rivers in the southeastern United States.

Journal: Environmental science & technology 20040801

Title: Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1.

Journal: Circulation research 20040723

Title: Combined therapy with deferiprone and desferrioxamine successfully regresses severe heart failure in patients with beta-thalassemia major.

Journal: Annals of hematology 20040701

Title: Hydroxyurea in the treatment of major beta-thalassemia and importance of genetic screening.

Journal: Annals of hematology 20040701

Title: Complications of beta-thalassemia major in North America.

Journal: Blood 20040701

Title: Value of sequential monitoring of left ventricular ejection fraction in the management of thalassemia major.

Journal: Blood 20040701

Title: Arterial calcifications and bone histomorphometry in end-stage renal disease.

Journal: Journal of the American Society of Nephrology : JASN 20040701

Title: Combined therapy with desferrioxamine and deferiprone: a new protocol for iron chelation in thalassemia.

Journal: Journal of pediatric hematology/oncology 20040701

Title: Lethal synergistic effect of cigarette smoke and saliva in an in vitro model: does saliva have a role in the development of oral cancer?

Journal: European journal of cancer (Oxford, England : 1990) 20040701

Title: Collision-induced dissociation tandem mass spectrometry of desferrioxamine siderophore complexes from electrospray ionization of UO2(2+), Fe3+ and Ca2+ solutions.

Journal: Journal of mass spectrometry : JMS 20040701

Title: Association of DNA-dependent protein kinase with hypoxia inducible factor-1 and its implication in resistance to anticancer drugs in hypoxic tumor cells.

Journal: Experimental & molecular medicine 20040630

Title: Competing pathways of iron chelation: angiogenesis or anti-tumor activity: targeting different molecules to induce specific effects.

Journal: International journal of cancer 20040620

Title: Hypoxia-dependent regulation of PHD1: cloning and characterization of the human PHD1/EGLN2 gene promoter.

Journal: FEBS letters 20040604

Title: Purging iron from the heart.

Journal: British journal of haematology 20040601

Title: Iron chelator triggers inflammatory signals in human intestinal epithelial cells: involvement of p38 and extracellular signal-regulated kinase signaling pathways.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20040601

Title: Inactivation of endoplasmic reticulum bound Ca2+-independent phospholipase A2 in renal cells during oxidative stress.

Journal: Journal of the American Society of Nephrology : JASN 20040601

Title: In vivo oxygen radical generation in the skin of the protoporphyria model mouse with visible light exposure: an L-band ESR study.

Journal: The Journal of investigative dermatology 20040601

Title: Bilateral vitelliform maculopathy and deferoxamine toxicity.

Journal: Retina (Philadelphia, Pa.) 20040601

Title: Molecular shuttle chelation: the use of ascorbate, desferrioxamine and Feralex-G in combination to remove nuclear bound aluminum.

Journal: Cellular and molecular neurobiology 20040601

Title: Lysosomal redox-active iron is important for oxidative stress-induced DNA damage.

Journal: Annals of the New York Academy of Sciences 20040601

Title: [Deep seated fungal infection in dialysis patients].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040601

Title: [Dialysis encephalopathy].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040601

Title: [Aluminum and iron deposition in dialysis patients].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040601

Title: Iron chelation abrogates excessive formation of hydroxyl radicals and lipid peroxidation products in monocytes of patients with Eales' disease: direct evidence using electron spin resonance spectroscopy.

Journal: Current eye research 20040601

Title: Transfusion haemosiderosis inspite of regular use of desferrioxamine: case report.

Journal: East African medical journal 20040601

Title: Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats.

Journal: Circulation 20040518

Title: Thy1 expression in the brain is affected by iron and is decreased in Restless Legs Syndrome.

Journal: Journal of the neurological sciences 20040515

Title: Conversion of the 2,2,6,6-tetramethylpiperidine moiety to a 2,2-dimethylpyrrolidine by cytochrome P450: evidence for a mechanism involving nitroxide radicals and heme iron.

Journal: Biochemistry 20040511

Title: Redox state of near infrared spectroscopy-measured cytochrome aa(3) correlates with delayed cerebral energy failure following perinatal hypoxia-ischaemia in the newborn pig.

Journal: Experimental brain research 20040501

Title: Type 3 hemochromatosis and beta-thalassemia trait.

Journal: European journal of haematology 20040501

Title: Iron chelation therapy in aceruloplasminaemia: study of a patient with a novel missense mutation.

Journal: Gut 20040501

Title: Unique features of recombinant heme oxygenase of Drosophila melanogaster compared with those of other heme oxygenases studied.

Journal: European journal of biochemistry 20040501

Title: Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production.

Journal: The Journal of clinical investigation 20040501

Title: Energy failure in astrocytes increases the vulnerability of neurons to spreading depression.

Journal: The European journal of neuroscience 20040501

Title: Cross talk between iron metabolism and diabetes.

Journal: Annals of clinical biochemistry 20040501

Title: Desferoxamine (DFO)--mediated iron chelation: rationale for a novel approach to therapy for brain cancer.

Journal: Journal of neuro-oncology 20040501

Title: Characterization and modulation of the transferrin receptor on brain capillary endothelial cells.

Journal: Pharmaceutical research 20040501

Title: [The K/DOQI guidelines on diagnosis and treatment of aluminum bone disease in hemodialysis patients].

Journal: Clinical calcium 20040501

Title: Iron oxide particles for molecular magnetic resonance imaging cause transient oxidative stress in rat macrophages.

Journal: Free radical biology & medicine 20040415

Title: Redox activity associated with the maturation and capacitation of mammalian spermatozoa.

Journal: Free radical biology & medicine 20040415

Title: Effect of nickel and iron co-exposure on human lung cells.

Journal: Toxicology and applied pharmacology 20040415

Title: Modulation of genotoxic effects in asbestos-exposed primary human mesothelial cells by radical scavengers, metal chelators and a glutathione precursor.

Journal: Mutation research 20040411

Title: Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha.

Journal: The Journal of biological chemistry 20040409

Title: Increased GADD153 gene expression during iron chelation-induced apoptosis in Jurkat T-lymphocytes.

Journal: Biochimica et biophysica acta 20040401

Title: Deferoxamine-induced attenuation of brain edema and neurological deficits in a rat model of intracerebral hemorrhage.

Journal: Journal of neurosurgery 20040401

Title: Free radical attenuation prevents thrombosis and enables photochemical inhibition of vein graft intimal hyperplasia.

Journal: Journal of vascular surgery 20040401

Title: Combined chelation therapy with deferiprone and desferrioxamine in iron overloaded beta-thalassemia patients.

Journal: Haematologica 20040401

Title: Mitochondrial dysfunction via disruption of complex II activity during iron chelation-induced senescence-like growth arrest of Chang cells.

Journal: Annals of the New York Academy of Sciences 20040401

Title: Validation of the transferrin receptor for drug targeting to brain capillary endothelial cells in vitro.

Journal: Journal of drug targeting 20040401

Title: Independent clinical trials.

Journal: Lancet (London, England) 20040327

Title: Hypoxic regulation of angiopoietin-2 expression in endothelial cells.

Journal: The Journal of biological chemistry 20040326

Title: Relocalized redox-active lysosomal iron is an important mediator of oxidative-stress-induced DNA damage.

Journal: The Biochemical journal 20040315

Title: Hypoxic up-regulation of triosephosphate isomerase expression in mouse brain capillary endothelial cells.

Journal: Archives of biochemistry and biophysics 20040315

Title: Effect on ribonucleotide reductase of novel lipophilic iron chelators: the desferri-exochelins.

Journal: Biochemical and biophysical research communications 20040312

Title: Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells.

Journal: Blood 20040301

Title: Picolinic acid- or desferrioxamine-inducible autocrine activation of macrophages engineered to produce IFNgamma: an approach for gene therapy.

Journal: Gene therapy 20040301

Title: Carbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia-inducible factor-1.

Journal: British journal of pharmacology 20040301

Title: Iron(III) complexation of Desferrioxamine B encapsulated in apoferritin.

Journal: Journal of inorganic biochemistry 20040301

Title: Iron accumulation, iron-mediated toxicity and altered levels of ferritin and transferrin receptor in cultured astrocytes during incubation with ferric ammonium citrate.

Journal: Journal of neurochemistry 20040301

Title: Extracellular calcium and magnesium, but not iron, are needed for optimal growth of Blastomyces dermatitidis yeast form cells in vitro.

Journal: Clinical and diagnostic laboratory immunology 20040301

Title: Deferoxamine administration in septic animals: improved survival and altered apoptotic gene expression.

Journal: International immunopharmacology 20040301

Title: [Bull's-Eye Maculopathy with Deferoxamine Treatment].

Journal: Klinische Monatsblatter fur Augenheilkunde 20040301

Title: Ironing iron out in Parkinson's disease and other neurodegenerative diseases with iron chelators: a lesson from 6-hydroxydopamine and iron chelators, desferal and VK-28.

Journal: Annals of the New York Academy of Sciences 20040301

Title: Effects of kojic acid on oxidative damage and on iron and trace element level in iron-overloaded mice and rats.

Journal: Central European journal of public health 20040301

Title: Ex-vivo and in vitro protective effects of kolaviron against oxygen-derived radical-induced DNA damage and oxidative stress in human lymphocytes and rat liver cells.

Journal: Cell biology and toxicology 20040301

Title: Role of cytochrome P4502E1 activation in proximal tubular cell injury induced by hydrogen peroxide.

Journal: Renal failure 20040301

Title: Reactions of desferrioxamine with peroxynitrite-derived carbonate and nitrogen dioxide radicals.

Journal: Free radical biology & medicine 20040215

Title: Thalassaemia major: the murky story of deferiprone.

Journal: BMJ (Clinical research ed.) 20040214

Title: Heme positively regulates the expression of beta-globin at the locus control region via the transcriptional factor Bach1 in erythroid cells.

Journal: The Journal of biological chemistry 20040213

Title: FhuF, part of a siderophore-reductase system.

Journal: Biochemistry 20040210

Title: Magnetic resonance screening of iron status in transfusion-dependent beta-thalassaemia patients.

Journal: British journal of haematology 20040201

Title: Hypoxia selectively inhibits monocyte chemoattractant protein-1 production by macrophages.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20040201

Title: Different mechanisms mediate uptake of lead in a rat astroglial cell line.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040201

Title: Desferrioxamine modulates chemically induced T helper 2-mediated autoimmunity in the rat.

Journal: Clinical and experimental immunology 20040201

Title: Treatment with N-acetylcysteine plus deferoxamine protects rats against oxidative stress and improves survival in sepsis.

Journal: Critical care medicine 20040201

Title: Therapeutic benefits of antioxidants during sepsis: is protection against oxidant-mediated tissue damage only half the story?

Journal: Critical care medicine 20040201

Title: Use of desferoxamine and S-adenosylmethionine to treat hemochromatosis in a red ruffed lemur (Varecia variegata ruber).

Journal: Comparative medicine 20040201

Title: [Vitamin B6-sensitive hereditary sideroblastic anemia].

Journal: Deutsche medizinische Wochenschrift (1946) 20040123

Title: Safety and efficacy of subcutaneous bolus injection of deferoxamine in adult patients with iron overload: an update.

Journal: Blood 20040115

Title: Nuclear accumulation of globular actin as a cellular senescence marker.

Journal: Cancer research 20040115

Title: Apolipoprotein E protects against oxidative stress in mixed neuronal-glial cell cultures by reducing glutamate toxicity.

Journal: Neurochemistry international 20040101

Title: Bone mass and metabolism in thalassemic children and adolescents treated with different iron-chelating drugs.

Journal: Journal of bone and mineral metabolism 20040101

Title: Iron: a target for the management of Kaposi's sarcoma?

Journal: BMC cancer 20040101

Title: Deferiprone versus deferoxamine in patients with thalassemia major: a randomized clinical trial.

Journal: Blood cells, molecules & diseases 20040101

Title: Comparative efficacy of desferrioxamine, deferiprone and in combination on iron chelation in thalassemic children.

Journal: Indian pediatrics 20040101

Title: Hydroxamate-based iron chelators: combinatorial syntheses of desferrioxamine B analogues and evaluation of binding affinities.

Journal: Journal of combinatorial chemistry 20040101

Title: [Uremic encephalopathy, dialysis encephalopathy].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040101

Title: The effects of desferrioxamine on cisplatin-induced lipid peroxidation and the activities of antioxidant enzymes in rat kidneys.

Journal: Human & experimental toxicology 20040101

Title: Deferoxamine antioxidant activity on cerebellar granule cells gamma-irradiated in vitro.

Journal: Neurotoxicology and teratology 20040101

Title: The effect of desferrioxamine on peroxynitrite-induced oxidative damage in erythrocytes.

Journal: Cell biochemistry and function 20040101

Title: Central venous line thrombosis in children and young adults with thalassemia major.

Journal: Pediatric hematology and oncology 20040101

Title: Study of intermittent intravenous deferrioxamine high-dose therapy in heavily iron-loaded children with beta-thalassemia major poorly compliant to subcutaneous injections.

Journal: Pediatric hematology and oncology 20040101

Title: Chemical nature, ligand denticity and quantification of fungal siderophores.

Journal: Indian journal of experimental biology 20040101

Title: Iron bezoar retained in colon despite 3 days of whole bowel irrigation.

Journal: Journal of toxicology. Clinical toxicology 20040101

Title: Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine.

Journal: Drug metabolism and drug interactions 20040101

Title: Long term audiological evaluation of beta-thalassemic patients.

Journal: Acta oto-rhino-laryngologica Belgica 20040101

Title: Effectiveness and safety of combined iron-chelation therapy with deferoxamine and deferiprone.

Journal: The hematology journal : the official journal of the European Haematology Association 20040101

Title: Iron chelators in cancer chemotherapy.

Journal: Current topics in medicinal chemistry 20040101

Title: Heme oxygenase-1 attenuates interleukin-1beta-induced nitric oxide synthase expression in vascular smooth muscle cells.

Journal: Journal of biomedical science 20040101

Title: Evidence of reactive oxygen species generation in synovial fluid from patients with temporomandibular disease by electron spin resonance spectroscopy.

Journal: Redox report : communications in free radical research 20040101

Title: Complex II defect via down-regulation of iron-sulfur subunit induces mitochondrial dysfunction and cell cycle delay in iron chelation-induced senescence-associated growth arrest.

Journal: The Journal of biological chemistry 20031219

Title: Congenital dyserythropoietic anemia type II: epidemiology, clinical appearance, and prognosis based on long-term observation.

Journal: Blood 20031215

Title: Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.

Journal: Cancer research 20031215

Title: Crystal and molecular structures of ionophore-siderophore host-guest supramolecular assemblies relevant to molecular recognition.

Journal: Journal of the American Chemical Society 20031203

Title: Deferoxamine reduces cold-ischemic renal injury in a syngeneic kidney transplant model.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20031201

Title: Effective treatment of hereditary haemochromatosis with desferrioxamine in selected cases.

Journal: British journal of haematology 20031201

Title: Combined therapy with desferrioxamine and deferiprone in thalassemic patients: effect on urinary iron excretion.

Journal: Haematologica 20031201

Title: Therapeutic angiogenesis for patients with limb ischemia by utilization of fibrin meshwork. Pilot randomized controlled study.

Journal: International angiology : a journal of the International Union of Angiology 20031201

Title: Activation of SRC tyrosine kinases in response to ICAM-1 ligation in pulmonary microvascular endothelial cells.

Journal: The Journal of biological chemistry 20031128

Title: Identification of hypoxia-response element in the human endothelial nitric-oxide synthase gene promoter.

Journal: The Journal of biological chemistry 20031121

Title: Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo.

Journal: FEBS letters 20031120

Title: Downregulation of p38 kinase pathway by cAMP response element-binding protein protects HL-60 cells from iron chelator-induced apoptosis.

Journal: Free radical biology & medicine 20031115

Title: In vivo identification of aflatoxin-induced free radicals in rat bile.

Journal: Free radical biology & medicine 20031115

Title: The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression.

Journal: Journal of hepatology 20031101

Title: Oxidative damage of DNA by the reaction of amino acid with methylglyoxal in the presence of Fe(III).

Journal: International journal of biological macromolecules 20031101

Title: Suppressive effect of iron on concanavalin A-induced multinucleated giant cell formation by human monocytes.

Journal: Immunological investigations 20031101

Title: A massive intraventricular thrombosis by disseminated mucormycosis in a patient with myelodysplastic syndrome during deferoxamine therapy.

Journal: Haematologica 20031101

Title: Pathophysiology of the optic neuropathy associated with Friedreich ataxia.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20031101

Title: Effects of iron modulation on growth and viability of Rhodococcus equi and expression of virulence-associated protein A.

Journal: American journal of veterinary research 20031101

Title: Oxygen tension regulates the expression of a group of procollagen hydroxylases.

Journal: European journal of biochemistry 20031101

Title: Deferoxamine prevents cardiac hypertrophy and failure in the gerbil model of iron-induced cardiomyopathy.

Journal: The Journal of laboratory and clinical medicine 20031101

Title: Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts.

Journal: The Journal of investigative dermatology 20031101

Title: Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells.

Journal: Experimental & molecular medicine 20031031

Title: Deferoxamine-induced attenuation of brain edema and neurological deficits in a rat model of intracerebral hemorrhage.

Journal: Neurosurgical focus 20031015

Title: Identification and prediction of promiscuous aggregating inhibitors among known drugs.

Journal: Journal of medicinal chemistry 20031009

Title: Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors.

Journal: Circulation research 20031003

Title: Effects of allopurinol and deferoxamine on reperfusion injury of the brain in newborn piglets after neonatal hypoxia-ischemia.

Journal: Pediatric research 20031001

Title: Acute renal failure following deferoxamine overdose.

Journal: Pediatric nephrology (Berlin, Germany) 20031001

Title: Preparation of 66Ga- and 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals.

Journal: Nuclear medicine and biology 20031001

Title: Deferoxamine and meropenem combination therapy in experimental acute pancreatitis.

Journal: Pancreas 20031001

Title: Pharmacotherapy of iron overload in thalassaemic patients.

Journal: Expert opinion on pharmacotherapy 20031001

Title: Endosomal and lysosomal effects of desferrioxamine: protection of HeLa cells from hydrogen peroxide-induced DNA damage and induction of cell-cycle arrest.

Journal: Free radical biology & medicine 20031001

Title: Protection of cells from menadione-induced apoptosis by inhibition of lipid peroxidation.

Journal: Toxicology 20030930

Title: Immobilization of Fe chelators on sepharose gel and its effect on their chemical properties.

Journal: Journal of agricultural and food chemistry 20030924

Title: Desferrioxamine treatment increases the genomic stability of Ataxia-telangiectasia cells.

Journal: DNA repair 20030918

Title: Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain.

Journal: Brain research. Molecular brain research 20030910

Title: Carrier-facilitated bulk liquid membrane transport of iron(III)-siderophore complexes utilizing first coordination sphere recognition.

Journal: Inorganic chemistry 20030908

Title: Air pollution particles produce airway wall remodeling in rat tracheal explants.

Journal: American journal of respiratory cell and molecular biology 20030901

Title: Iron chelation, angiogenesis and tumor therapy.

Journal: International journal of cancer 20030901

Title: Deferoxamine reduces and nitric oxide synthase inhibition increases neutrophil-mediated myotube injury.

Journal: Cell and tissue research 20030901

Title: Chromosomal aberration frequencies in patients with thalassaemia major undergoing therapy with deferiprone and deferoxamine in a comparative crossover study.

Journal: Mutagenesis 20030901

Title: A massive intraventricular thrombosis by disseminated mucormycosis in a patient with myelodysplastic syndrome during deferoxamine therapy.

Journal: Haematologica 20030901

Title: Malaria: to kill a parasite.

Journal: Nature 20030821

Title: Artemisinins target the SERCA of Plasmodium falciparum.

Journal: Nature 20030821

Title: Cold-induced apoptosis of rat liver endothelial cells: contribution of mitochondrial alterations.

Journal: Transplantation 20030815

Title: Do we need more iron-chelating drugs?

Journal: Lancet (London, England) 20030809

Title: Regulation of c-myc gene by nitric oxide via inactivating NF-kappa B complex in P19 mouse embryonal carcinoma cells.

Journal: The Journal of biological chemistry 20030808

Title: Cytotoxicity of RH1 and related aziridinylbenzoquinones: involvement of activation by NAD(P)H:quinone oxidoreductase (NQO1) and oxidative stress.

Journal: Archives of biochemistry and biophysics 20030801

Title: Pathways for the regulation of interferon-gamma-inducible genes by iron in human monocytic cells.

Journal: Journal of leukocyte biology 20030801

Title: Current status of metals as therapeutic targets in Alzheimer's disease.

Journal: Journal of the American Geriatrics Society 20030801

Title: Dopamine release rather than content in the caudate putamen is associated with behavioral changes in the iron rat model of Parkinson's disease.

Journal: Experimental neurology 20030801

Title: Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20030801

Title: The protective and therapeutic effects of zinc chloride and desferrioxamine on skin exposed to nitrogen mustard.

Journal: Military medicine 20030801

Title: Oxalate deposition on asbestos bodies.

Journal: Human pathology 20030801

Title: Transcriptional effects of hypoxia on fusiogenic syncytin and its receptor ASCT2 in human cytotrophoblast BeWo cells and in ex vivo perfused placental cotyledons.

Journal: American journal of obstetrics and gynecology 20030801

Title: Effect of hypoxia on the expression of fractalkine in human endothelial cells.

Journal: The Tohoku journal of experimental medicine 20030801

Title: Expression of proinflammatory cytokines via HIF-1alpha and NF-kappaB activation on desferrioxamine-stimulated HMC-1 cells.

Journal: Biochemical and biophysical research communications 20030711

Title: Pro-apoptotic signaling in neuronal cells following iron and amyloid beta peptide neurotoxicity.

Journal: Journal of neurochemistry 20030701

Title: Performance characteristics of the Dimension RxL iron and total iron-binding capacity methods.

Journal: Clinica chimica acta; international journal of clinical chemistry 20030701

Title: Iron withdrawal strategies fail to prevent the growth of SiHa-induced tumors in mice.

Journal: Gynecologic oncology 20030701

Title: Injury induced by chemical warfare agents: characterization and treatment of ocular tissues exposed to nitrogen mustard.

Journal: Investigative ophthalmology & visual science 20030701

Title: Iron chelators for the treatment of iron overload disease: relationship between structure, redox activity, and toxicity.

Journal: American journal of hematology 20030701

Title: A preliminary evaluation of a new selective agar supplemented with desferrioxamine for detection of methicillin-resistant Staphylococcus aureus.

Journal: The Journal of hospital infection 20030701

Title: The effect of an iron chelating agent on protoporphyrin IX levels and phototoxicity in topical 5-aminolaevulinic acid photodynamic therapy.

Journal: The British journal of dermatology 20030701

Title: Non-invasive analysis of reactive oxygen species generated in NH4OH-induced gastric lesions of rats using a 300 MHz in vivo ESR technique.

Journal: Free radical research 20030701

Title: [Recent progress of doping tests in sports].

Journal: Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20030701

Title: Calcein as a fluorescent iron chemosensor for the determination of low molecular weight iron in biological fluids.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20030601

Title: Evaluation of myocardial iron by magnetic resonance imaging during iron chelation therapy with deferrioxamine: indication of close relation between myocardial iron content and chelatable iron pool.

Journal: Blood 20030601

Title: Iron chelators as anti-neoplastic agents: current developments and promise of the PIH class of chelators.

Journal: Current medicinal chemistry 20030601

Title: Safety monitoring of cardiac and hepatic systems in beta-thalassemia patients with chelating treatment in Taiwan.

Journal: European journal of haematology 20030601

Title: Reversal of cardiac complications in thalassemia major by long-term intermittent daily intensive iron chelation.

Journal: European journal of haematology 20030601

Title: Bull's eye maculopathy with deferoxamine.

Journal: European journal of haematology 20030601

Title: Monitoring long-term efficacy of iron chelation therapy by deferiprone and desferrioxamine in patients with beta-thalassaemia major: application of SQUID biomagnetic liver susceptometry.

Journal: British journal of haematology 20030601

Title: Potent iron chelators increase the mRNA levels of the universal cyclin-dependent kinase inhibitor p21(CIP1/WAF1), but paradoxically inhibit its translation: a potential mechanism of cell cycle dysregulation.

Journal: Carcinogenesis 20030601

Title: Effects of deferoxamine on tissue lactate and malondialdehyde levels in cerebral ischemia.

Journal: Methods and findings in experimental and clinical pharmacology 20030601

Title: Stimulation of Na,K-ATPase by low potassium is dependent on transferrin.

Journal: The Journal of membrane biology 20030601

Title: Malaria in endemic areas.

Journal: Clinical evidence 20030601

Title: Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells.

Journal: Blood 20030515

Title: Intralysosomal iron: a major determinant of oxidant-induced cell death.

Journal: Free radical biology & medicine 20030515

Title: Prevention of oxidant-induced cell death by lysosomotropic iron chelators.

Journal: Free radical biology & medicine 20030515

Title: Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial.

Journal: Lancet (London, England) 20030510

Title: Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha.

Journal: The Journal of biological chemistry 20030502

Title: Relationships and distinctions in iron-regulatory networks responding to interrelated signals.

Journal: Blood 20030501

Title: Characterization of myoglobin toxicity in renal cortical slices from Fischer 344 rats.

Journal: Toxicology 20030501

Title: Surgical resection of multiple right atrial masses in a child with beta thalassaemia and receiving desferioxamine.

Journal: Heart (British Cardiac Society) 20030501

Title: Regulation of heme oxygenase-1 gene expression by anoxia and reoxygenation in primary rat hepatocyte cultures.

Journal: Experimental biology and medicine (Maywood, N.J.) 20030501

Title: Iron chelators inhibit VCAM-1 expression in human dermal microvascular endothelial cells.

Journal: The Journal of investigative dermatology 20030501

Title: Treatment of cardiac iron overload in thalassemia major.

Journal: Haematologica 20030501

Title: Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: a retrospective analysis.

Journal: Haematologica 20030501

Title: Cardiac autonomic dysinnervation and myocardial blood flow in long-term Type 1 diabetic patients.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20030501

Title: Deferoxamine improves early postresuscitation reperfusion after prolonged cardiac arrest in rats.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030501

Title: Potential myocardial iron content evaluation by magnetic resonance imaging in thalassemia major patients treated with Deferoxamine or Deferiprone during a randomized multicenter prospective clinical study.

Journal: Hemoglobin 20030501

Title: Tyrosine kinase is involved in hemin-induced pyresis.

Journal: Archives of pharmacal research 20030501

Title: 1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide.

Journal: The Biochemical journal 20030401

Title: The antimycotic ciclopirox olamine induces HIF-1alpha stability, VEGF expression, and angiogenesis.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401

Title: Urine biochemical markers of early renal dysfunction are associated with iron overload in beta-thalassaemia.

Journal: Clinical and laboratory haematology 20030401

Title: Comparison between desferrioxamine and combined therapy with desferrioxamine and deferiprone in iron overloaded thalassaemia patients.

Journal: British journal of haematology 20030401

Title: Treatment of dyskeratosis congenita with granulocyte-macrophage colony-stimulating factor and erythropoietin.

Journal: Journal of pediatric hematology/oncology 20030401

Title: Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells.

Journal: European journal of biochemistry 20030401

Title: Quantitative evaluation of the retinal venous tortuosity in chronic anaemic patients affected by beta-thalassaemia major.

Journal: Eye (London, England) 20030401

Title: Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells.

Journal: Free radical biology & medicine 20030315

Title: Correlation of iron and zinc levels with lesion depth in newly formed atherosclerotic lesions.

Journal: Free radical biology & medicine 20030315

Title: Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells.

Journal: The Journal of biological chemistry 20030314

Title: Protective effects of flavonoids on the cytotoxicity of linoleic acid hydroperoxide toward rat pheochromocytoma PC12 cells.

Journal: Chemico-biological interactions 20030306

Title: Characterization of myoglobin toxicity in renal cortical slices from Fischer 344 rats.

Journal: Toxicology 20030303

Title: Involvement of the mitochondrial pathway in cold storage and rewarming-associated apoptosis of human renal proximal tubular cells.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030301

Title: Acute renal failure following deferoxamine overdose.

Journal: Pediatric nephrology (Berlin, Germany) 20030301

Title: The dangers of iron overload in pyruvate kinase deficiency.

Journal: British journal of haematology 20030301

Title: Fluoride-induced apoptosis in human epithelial lung cells (A549 cells): role of different G protein-linked signal systems.

Journal: Human & experimental toxicology 20030301

Title: Cell proliferation induced by reactive oxygen species is mediated via mitogen-activated protein kinase in Chinese hamster lung fibroblast (V79) cells.

Journal: Molecules and cells 20030227

Title: Deferoxamine, allopurinol and oxypurinol are not neuroprotective after oxygen/glucose deprivation in an organotypic hippocampal model, lacking functional endothelial cells.

Journal: Brain research 20030214

Title: Inhibitory activity of epigallocatechin gallate (EGCg) in paraquat-induced microsomal lipid peroxidation--a mechanism of protective effects of EGCg against paraquat toxicity.

Journal: Toxicology 20030201

Title: Deferoxamine promotes survival and prevents electrocardiographic abnormalities in the gerbil model of iron-overload cardiomyopathy.

Journal: The Journal of laboratory and clinical medicine 20030201

Title: Preventative effect of deferoxamine on degenerative changes in the optic nerve in experimental retrobulbar haematoma.

Journal: Clinical & experimental ophthalmology 20030201

Title: In vitro activation of dibromoacetonitrile to cyanide: role of xanthine oxidase.

Journal: Archives of toxicology 20030201

Title: Protective effect of desferrioxamine during canine liver transplantation: significance of peritransplant liver biopsy.

Journal: Transplantation proceedings 20030201

Title: Changes in function of iron-loaded alveolar macrophages after in vivo administration of desferrioxamine and/or chloroquine.

Journal: Journal of inorganic biochemistry 20030201

Title: Ageing exacerbates the cardiotoxicity of hydrogen peroxide through the Fenton reaction in rats.

Journal: Mechanisms of ageing and development 20030201

Title: Formation of reactive oxygen species in rat epithelial cells upon stimulation with fly ash.

Journal: Journal of biosciences 20030201

Title: Cytosolic aconitase and ferritin are regulated by iron in Caenorhabditis elegans.

Journal: The Journal of biological chemistry 20030131

Title: A novel trivalent cation chelator Feralex dissociates binding of aluminum and iron associated with hyperphosphorylated tau of Alzheimer's disease.

Journal: Brain research 20030124

Title: Butyrate impairs intestinal tumor cell-induced angiogenesis by inhibiting HIF-1alpha nuclear translocation.

Journal: Biochemical and biophysical research communications 20030124

Title: Genetic regulation of cell function in response to iron overload or chelation.

Journal: Biochimica et biophysica acta 20030120

Title: Deferiprone versus desferrioxamine in thalassaemia, and T2* validation and utility.

Journal: Lancet (London, England) 20030111

Title: Deferiprone versus desferrioxamine in thalassaemia, and T2* validation and utility.

Journal: Lancet (London, England) 20030111

Title: Deferiprone versus desferrioxamine in thalassaemia, and T2* validation and utility.

Journal: Lancet (London, England) 20030111

Title: Deferiprone versus desferrioxamine in thalassaemia, and T2* validation and utility.

Journal: Lancet (London, England) 20030111

Title: Relationship between hepatocellular injury and transfusional iron overload prior to and during iron chelation with desferrioxamine: a study in adult patients with acquired anemias.

Journal: Blood 20030101

Title: Attenuation of glycerol-induced acute renal failure in rats by trimetazidine and deferoxamine.

Journal: Pharmacology 20030101

Title: Antihistone and other autoantibodies in beta-thalassemia major patients receiving iron chelators.

Journal: Acta haematologica 20030101

Title: Deferoxamine enhances neovascularization and recovery of ischemic skeletal muscle in an experimental sheep model.

Journal: The Annals of thoracic surgery 20030101

Title: Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030101

Title: A sensitive test for early myocardial iron loading.

Journal: European heart journal 20030101

Title: Tissue Doppler echocardiography in patients with thalassaemia detects early myocardial dysfunction related to myocardial iron overload.

Journal: European heart journal 20030101

Title: [Successful treatment of haemodialysis-related porphyria cutanea tarda with deferoxamine].

Journal: Annales de dermatologie et de venereologie 20030101

Title: Neutrophil apoptosis in patients with beta-thalassemia major.

Journal: Pediatric hematology and oncology 20030101

Title: Iron release in erythrocytes and plasma non protein-bound iron in hypoxic and non hypoxic newborns.

Journal: Free radical research 20030101

Title: [Effect of desferrioxamine and deferiprone on osteocalcin secretion in osteoblast-type cells].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20030101

Title: Benefits and risks of deferiprone in iron overload in Thalassaemia and other conditions: comparison of epidemiological and therapeutic aspects with deferoxamine.

Journal: Drug safety 20030101

Title: [The in vitro release of hydroxyl radicals from dust containing fluoro-edenite fibers identified in the volcanic rocks of Biancavilla (eastern Sicily)].

Journal: La Medicina del lavoro 20030101

Title: Iron chelation in chemotherapy.

Journal: Advances in applied microbiology 20030101

Title: [Effect of daphnetin on SOD activity and DNA synthesis of Plasmodium falciparum in vitro].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20030101

Title: Immune status of thalassemic patients receiving deferiprone or combined deferiprone and desferrioxamine chelation treatment.

Journal: Acta haematologica 20030101

Title: Comparative study of intravenous ascorbic acid versus low-dose desferroxamine in patients on hemodialysis with hyperferritinemia.

Journal: Journal of nephrology 20030101

Title: Thalassemia: the facts and the controversies.

Journal: Pediatric nursing 20030101

Title: Deferoxamine-fibrin accelerates angiogenesis in a rabbit model of peripheral ischemia.

Journal: Vascular medicine (London, England) 20030101

Title: Prevalence of endocrine complications in beta-thalassaemia major in the Islamic Republic of Iran.

Journal: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20030101

Title: Regulation of xanthine oxidoreductase by intracellular iron.

Journal: American journal of physiology. Cell physiology 20021201

Title: Chemical aspects of siderophore mediated iron transport.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20021201

Title: A mycobacterial iron chelator, desferri-exochelin, induces hypoxia-inducible factors 1 and 2, NIP3, and vascular endothelial growth factor in cancer cell lines.

Journal: Cancer research 20021201

Title: Dihydroisotanshinone I protects against menadione-induced toxicity in a primary culture of rat hepatocytes.

Journal: Planta medica 20021201

Title: Effect of the iron chelator deferoxamine on Trichomonas vaginalis in vitro.

Journal: Journal of the Egyptian Society of Parasitology 20021201

Title: Involvement of p38 MAP kinase during iron chelator-mediated apoptotic cell death.

Journal: Cellular immunology 20021201

Title: An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript.

Journal: The Journal of biological chemistry 20021122

Title: Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo.

Journal: American journal of physiology. Lung cellular and molecular physiology 20021101

Title: Role of bioavailable iron in coal dust-induced activation of activator protein-1 and nuclear factor of activated T cells: difference between Pennsylvania and Utah coal dusts.

Journal: American journal of respiratory cell and molecular biology 20021101

Title: Pharmacological interventions in the newborn piglet in the first 24 h after hypoxia-ischemia. A hemodynamic and electrophysiological perspective.

Journal: Experimental brain research 20021101

Title: Cellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up.

Journal: Carcinogenesis 20021101

Title: Urinary iron excretion induced by intravenous infusion of deferoxamine in beta-thalassemia homozygous patients.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20021101

Title: Congenital erythropoietic porphyria: dilemmas in present day management.

Journal: Clinical and experimental dermatology 20021101

Title: Acute iron ingestion.

Journal: Indian journal of pediatrics 20021101

Title: Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha.

Journal: The Journal of biological chemistry 20021018

Title: Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis.

Journal: Blood 20021015

Title: Enhanced activity of human IL-10 after nitration in reducing human IL-1 production by stimulated peripheral blood mononuclear cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20021015

Title: The labile iron pool: characterization, measurement, and participation in cellular processes(1).

Journal: Free radical biology & medicine 20021015

Title: In vivo detection of aflatoxin-induced lipid free radicals in rat bile.

Journal: Biochimica et biophysica acta 20021010

Title: Reactive oxygen species generated during myocardial ischemia enable energetic recovery during reperfusion.

Journal: American journal of physiology. Heart and circulatory physiology 20021001

Title: The effects of desferrioxamin and vitamin E as supplements to antibiotics in the treatment of peritonitis in rats.

Journal: Journal of the Royal College of Surgeons of Edinburgh 20021001

Title: Increased release of free Fe ions in human erythrocytes during aging in the circulation.

Journal: Free radical research 20021001

Title: Iron chelation-induced senescence-like growth arrest in hepatocyte cell lines: association of transforming growth factor beta1 (TGF-beta1)-mediated p27Kip1 expression.

Journal: The Biochemical journal 20020901

Title: Induction of ferritin and lipid peroxidation by coal samples with different prevalence of coal workers' pneumoconiosis: role of iron in the coals.

Journal: American journal of industrial medicine 20020901

Title: Response of Staphylococcus aureus isolates from bovine mastitis to exogenous iron sources.

Journal: Journal of dairy science 20020901

Title: Proapoptotic and redox state-related signaling of reactive oxygen species generated by transformed fibroblasts.

Journal: Oncogene 20020829

Title: [An older female patient with refractory anemia and hemochromatosis].

Journal: Deutsche medizinische Wochenschrift (1946) 20020823

Title: Deferiprone: greater efficacy at depleting myocardial than hepatic iron?

Journal: Lancet (London, England) 20020817

Title: Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia.

Journal: Lancet (London, England) 20020817

Title: A novel iron chelator that does not induce HIF-1 activity.

Journal: Free radical biology & medicine 20020801

Title: Peroxynitrite and the regulation of Na(+),K(+)-ATPase activity by angiotensin II in the rat proximal tubule.

Journal: Nitric oxide : biology and chemistry 20020801

Title: Ferritin and desferrioxamine attenuate xanthine oxidase-dependent leak in isolated perfused rat lungs.

Journal: Inflammation 20020801

Title: Cold induces catalytic iron release of cytochrome P-450 origin: a critical step in cold storage-induced renal injury.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020801

Title: Platelet-activating factor enhances the expression of vascular endothelial growth factor in normal human astrocytes.

Journal: Brain research 20020719

Title: Desferrioxamine enhances AIDS-associated Kaposi's sarcoma tumor development in a xenograft model.

Journal: International journal of cancer 20020710

Title: Innate defense evicts bacterial squatters.

Journal: Nature immunology 20020701

Title: Low-dose doxorubicin-induced necrosis in Jurkat cells and its acceleration and conversion to apoptosis by antioxidants.

Journal: British journal of haematology 20020701

Title: Patterns of bone diseases in transfusion-dependent homozygous thalassaemia major: predominance of osteoporosis and desferrioxamine-induced bone dysplasia.

Journal: Pediatric radiology 20020701

Title: Deferoxamine improves coronary vascular responses to sympathetic stimulation in patients with type 1 diabetes mellitus.

Journal: European journal of nuclear medicine and molecular imaging 20020701

Title: Solution equilibria of deferoxamine amides.

Journal: Journal of pharmaceutical sciences 20020701

Title: The mechanism of nitrogen monoxide (NO)-mediated iron mobilization from cells. NO intercepts iron before incorporation into ferritin and indirectly mobilizes iron from ferritin in a glutathione-dependent manner.

Journal: European journal of biochemistry 20020701

Title: ERK activation and nuclear translocation in amyloid-beta peptide- and iron-stressed neuronal cell cultures.

Journal: The European journal of neuroscience 20020701

Title: Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia.

Journal: Circulation research 20020628

Title: Induction of an outer membrane protein of 78 kDa in Vibrio vulnificus cultured in the presence of desferrioxamine B under iron-limiting conditions.

Journal: FEMS microbiology letters 20020618

Title: Flavopiridol inhibits vascular endothelial growth factor production induced by hypoxia or picolinic acid in human neuroblastoma.

Journal: International journal of cancer 20020610

Title: Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020601

Title: Gene promoter of apoptosis inhibitory protein IAP2: identification of enhancer elements and activation by severe hypoxia.

Journal: The Biochemical journal 20020601

Title: Retinoic acid receptor-related orphan receptor (ROR) alpha4 is the predominant isoform of the nuclear receptor RORalpha in the liver and is up-regulated by hypoxia in HepG2 human hepatoma cells.

Journal: The Biochemical journal 20020601

Title: Aceruloplasminemia: new clinical, pathophysiological and therapeutic insights.

Journal: Journal of hepatology 20020601

Title: [Ocular toxicity of deferoxamine: description and analysis of three observations].

Journal: Journal francais d'ophtalmologie 20020601

Title: Nitric oxide inhibits the shedding of the glycosylphosphatidylinositol-anchored dipeptidase from porcine renal proximal tubules.

Journal: The Biochemical journal 20020515

Title: Reversibility of cirrhosis in patients cured of thalassemia by bone marrow transplantation.

Journal: Annals of internal medicine 20020507

Title: Summaries for patients. Reversibility of liver scarring in patients who are cured of thalassemia.

Journal: Annals of internal medicine 20020507

Title: A zinc-finger protein, PLAGL2, induces the expression of a proapoptotic protein Nip3, leading to cellular apoptosis.

Journal: The Journal of biological chemistry 20020503

Title: A venom extract from the sea anemone Bartholomea annulata produces haemolysis and lipid peroxidation in mouse erythrocytes.

Journal: Toxicology 20020501

Title: Expression of the two mRNA isoforms of the iron transporter Nramp2/DMTI in mice and function of the iron responsive element.

Journal: The Biochemical journal 20020501

Title: Liver disease in transfusion dependent thalassaemia major.

Journal: Archives of disease in childhood 20020501

Title: Desferrioxamine induces delayed tolerance against cerebral ischemia in vivo and in vitro.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020501

Title: Role of the haem oxygenase-carbon monoxide pathway in insulin-induced hypothermia: evidence for carbon monoxide involvement.

Journal: Pflugers Archiv : European journal of physiology 20020501

Title: Brucella abortus siderophore 2,3-dihydroxybenzoic acid (DHBA) facilitates intracellular survival of the bacteria.

Journal: Microbial pathogenesis 20020501

Title: Utilization and cell-surface binding of hemin by Histoplasma capsulatum.

Journal: Canadian journal of microbiology 20020501

Title: Melatonin improves deferoxamine antioxidant activity in protecting against lipid peroxidation caused by hydrogen peroxide in rat brain homogenates.

Journal: Neuroscience letters 20020419

Title: HBED ligand: preclinical studies of a potential alternative to deferoxamine for treatment of chronic iron overload and acute iron poisoning.

Journal: Blood 20020415

Title: Reduction of iron by extracellular iron reductases: implications for microbial iron acquisition.

Journal: Archives of biochemistry and biophysics 20020415

Title: Growth inhibition of bloodstream forms of Trypanosoma brucei by the iron chelator deferoxamine.

Journal: International journal for parasitology 20020401

Title: Interaction of irinotecan (CPT-11) and its active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38) with human cytochrome P450 enzymes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020401

Title: Iron chelation via deferoxamine exacerbates experimental salmonellosis via inhibition of the nicotinamide adenine dinucleotide phosphate oxidase-dependent respiratory burst.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020401

Title: Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species.

Journal: American journal of respiratory cell and molecular biology 20020401

Title: Antiproliferative and apoptotic effects of iron chelators on human cervical carcinoma cells.

Journal: Gynecologic oncology 20020401

Title: Effect of the iron chelator desferrioxamine on manganese-induced toxicity of rat pheochromocytoma (PC12) cells.

Journal: Journal of neuroscience research 20020401

Title: Evidence that hydroxyl radicals mediate auxin-induced extension growth.

Journal: Planta 20020401

Title: Deferoxamine and hespan complex as a resuscitative adjuvant in hemorrhagic shock rat model.

Journal: Shock (Augusta, Ga.) 20020401

Title: Mechanisms of oxygen sensing in human trophoblast cells.

Journal: Placenta 20020401

Title: Prevention of the areca nut extract-induced unscheduled DNA synthesis of gingival keratinocytes by vitamin C and thiol compounds.

Journal: Oral oncology 20020401

Title: Heme oxygenase activity modulates vascular endothelial growth factor synthesis in vascular smooth muscle cells.

Journal: Antioxidants & redox signaling 20020401

Title: [Acquired idiopathic sideroblastic anemia].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020401

Title: Osteoporosis and beta-thalassemia major: role of the IGF-I/IGFBP-III axis.

Journal: Journal of endocrinological investigation 20020401

Title: An examination of heme action in gene expression: heme and heme deficiency affect the expression of diverse genes in erythroid k562 and neuronal PC12 cells.

Journal: DNA and cell biology 20020401

Title: [Study on silica induced DNA damage and its influence factor].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20020401

Title: Histidines 578 and 587 in the S5-S6 linker of the human Ether-a-gogo Related Gene-1 K+ channels confer sensitivity to reactive oxygen species.

Journal: The Journal of biological chemistry 20020315

Title: Cleavage of the fifth component of human complement and release of a split product with C5a-like activity by crystalline silica through free radical generation and kallikrein activation.

Journal: Toxicology and applied pharmacology 20020315

Title: The influence of deferiprone (L1) and deferoxamine on iron and essential element tissue level and parameters of oxidative status in dietary iron-loaded mice.

Journal: Toxicology letters 20020310

Title: Ca(2+)-activated K+ channel inhibition by reactive oxygen species.

Journal: American journal of physiology. Cell physiology 20020301

Title: Placental ceruloplasmin homolog is regulated by iron and copper and is implicated in iron metabolism.

Journal: American journal of physiology. Cell physiology 20020301

Title: Antioxidants inhibit mercuric chloride-induced early vasculitis.

Journal: International immunology 20020301

Title: Coronary microvascular adaptation to myocardial metabolic demand can be restored by inhibition of iron-catalyzed formation of oxygen free radicals in type 2 diabetic patients.

Journal: Diabetes 20020301

Title: Labile iron in parenteral iron formulations and its potential for generating plasma nontransferrin-bound iron in dialysis patients.

Journal: European journal of clinical investigation 20020301

Title: Iron chelation and hydroxyl radical scavenging reduce the inflammatory response of endothelial cells after infection with Chlamydia pneumoniae or influenza A.

Journal: European journal of clinical investigation 20020301

Title: Desferrithiocin is a more potent antineoplastic agent than desferrioxamine.

Journal: British journal of pharmacology 20020301

Title: Iron enhancement of oxidative DNA damage and neuronal cell death induced by salsolinol.

Journal: Journal of toxicology and environmental health. Part A 20020301

Title: Amelioration of cerulein-induced acute pancreatitis by 2,2'-dipyridyl in rats.

Journal: [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20020301

Title: Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect.

Journal: The Journal of biological chemistry 20020222

Title: Production of carbon monoxide by cytochrome P450 during iron-dependent lipid peroxidation.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20020201

Title: Stored iron and myocardial perfusion deficits.

Journal: American heart journal 20020201

Title: Brain edema after experimental intracerebral hemorrhage: role of hemoglobin degradation products.

Journal: Journal of neurosurgery 20020201

Title: Iron deficiency can upregulate expression of transferrin receptor at both the mRNA and protein level.

Journal: British journal of haematology 20020201

Title: Steady-state dissolution kinetics of aluminum-goethite in the presence of desferrioxamine-B and oxalate ligands.

Journal: Environmental science & technology 20020201

Title: Iron contributes to endothelial dysfunction in acute ischemic syndromes.

Journal: Circulation 20020129

Title: Amyloid-beta-protein (A beta) (25-35)-associated free radical generation is strongly influenced by the aggregational state of the peptides.

Journal: Life sciences 20020104

Title: Ferrous ion autoxidation and its chelation in iron-loaded human liver HepG2 cells.

Journal: Free radical biology & medicine 20020101

Title: The expanded clinical spectrum of deferoxamine retinopathy.

Journal: Ophthalmology 20020101

Title: Acquisition, storage and release of iron by cultured human hepatoma cells.

Journal: Journal of hepatology 20020101

Title: Blood and blisters: porphyria cutanea tarda in myelodysplastic syndrome.

Journal: British journal of haematology 20020101

Title: The iron-loaded gerbil model revisited: effects of deferoxamine and deferiprone treatment.

Journal: The Journal of laboratory and clinical medicine 20020101

Title: Quantitation of intracellular free iron by electron paramagnetic resonance spectroscopy.

Journal: Methods in enzymology 20020101

Title: Impact of thalassemia major on patients and their families.

Journal: Acta haematologica 20020101

Title: An international survey of patients with thalassemia major and their views about sustaining life-long desferrioxamine use.

Journal: BMC clinical pharmacology 20020101

Title: Deferiprone versus deferoxamine in patients with thalassemia major: a randomized clinical trial.

Journal: Blood cells, molecules & diseases 20020101

Title: Enhancement of classic Kaposi's sarcoma growth after intralesional injections of desferrioxamine.

Journal: Dermatology (Basel, Switzerland) 20020101

Title: Experimental study on effects of deferoxamine mesilate in ameliorating cisplatin-induced nephrotoxicity.

Journal: International urology and nephrology 20020101

Title: Pulmonary iron overload in thalassemia major presenting as small airway disease.

Journal: Acta haematologica 20020101

Title: Generation of reactive oxygen species in the enzymatic reduction of PbCrO4 and related DNA damage.

Journal: Molecular and cellular biochemistry 20020101

Title: Soluble metals as well as the insoluble particle fraction are involved in cellular DNA damage induced by particulate matter.

Journal: Molecular and cellular biochemistry 20020101

Title: Evaluation of the incidence of sensorineural hearing loss in beta-thalassemia major patients under regular chelation therapy with desferrioxamine.

Journal: Acta haematologica 20020101

Title: Low-density lipoprotein modification by normal, myeloperoxidase-deficient and NADPH oxidase-deficient granulocytes and the impact of redox active transition metal ions.

Journal: Redox report : communications in free radical research 20020101

Title: Differential effects of iron deficiency on the expression of CD80 and CD86 co-stimulatory receptors in mitogen-treated and untreated murine spleen cells.

Journal: Journal of cellular biochemistry 20020101

Title: Effect of deferoxamine and L-arginine treatment on lipid peroxidation in an intestinal ischaemia-reperfusion model in rats.

Journal: Acta veterinaria Hungarica 20020101

Title: Growth and puberty and its management in thalassaemia.

Journal: Hormone research 20020101

Title: [Generation of hydroxyl radicals and other redox active compounds in the sea water exposed to heat].

Journal: Biofizika 20020101

Title: Desferrioxamine decreases NAD redox potential of intact red blood cells: evidence for desferrioxamine as an inducer of oxidant stress in red blood cells.

Journal: BMC clinical pharmacology 20020101

Title: Numerous proteins in Mammalian cells are prone to iron-dependent oxidation and proteasomal degradation.

Journal: Developmental neuroscience 20020101

Title: Deferoxamine attenuates iron-induced oxidative stress and prevents mitochondrial aggregation and alpha-synuclein translocation in SK-N-SH cells in culture.

Journal: Developmental neuroscience 20020101

Title: Contribution of ferrous iron to maintenance of the gastric colonization of Helicobacter pylori in miniature pigs.

Journal: Microbiological research 20020101

Title: Growth of thorax in genetic anemias: an index of deficit.

Journal: Archives of medical research 20020101

Title: Oxidative stress reproduces placental abnormalities of preeclampsia.

Journal: Hypertension in pregnancy 20020101

Title: Induction of apoptosis by iron depletion in the human breast cancer MCF-7 cell line and the 13762NF rat mammary adenocarcinoma in vivo.

Journal: Anticancer research 20020101

Title: In vitro antimalarial effect of daphnetin relating to its iron-chelating activity.

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20020101

Title: Intracellular and extracellular labile iron pools.

Journal: Advances in experimental medicine and biology 20020101

Title: Results of long term iron chelation treatment with deferoxamine.

Journal: Advances in experimental medicine and biology 20020101

Title: Long term deferiprone chelation therapy.

Journal: Advances in experimental medicine and biology 20020101

Title: Therapeutic potential of iron chelators in cancer therapy.

Journal: Advances in experimental medicine and biology 20020101

Title: Antimalarial effect of iron chelators.

Journal: Advances in experimental medicine and biology 20020101

Title: Effect of proteins and amino acids on oxidation of liposomes by hydroxyl and peroxyl free radicals.

Journal: Redox report : communications in free radical research 20020101

Title: Multiple pathways of neuroprotection against oxidative stress and excitotoxic injury in immature primary hippocampal neurons.

Journal: Brain research. Developmental brain research 20011231

Title: Structure-function investigation of the interaction of 1- and 2-substituted 3-hydroxypyridin-4-ones with 5-lipoxygenase and ribonucleotide reductase.

Journal: The Journal of biological chemistry 20011228

Title: Iron prevents ferritin turnover in hepatic cells.

Journal: The Journal of biological chemistry 20011228

Title: Three cell wall mannoproteins facilitate the uptake of iron in Saccharomyces cerevisiae.

Journal: The Journal of biological chemistry 20011228

Title: Cellular zinc content is a major determinant of iron chelator-induced apoptosis of thymocytes.

Journal: Blood 20011215

Title: Effect of iron chelators on proliferation and iron uptake in hepatoma cells.

Journal: Cancer 20011215

Title: Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells. Reactive oxygen species and mitochondrial inner membrane permeabilization.

Journal: The Journal of biological chemistry 20011214

Title: Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy: role of reactive oxygen species and NADPH oxidase.

Journal: Circulation 20011211

Title: Reversible inhibition of hypoxia-inducible factor 1 activation by exposure of hypoxic cells to the volatile anesthetic halothane.

Journal: FEBS letters 20011207

Title: Action of deferoxamine against Pneumocystis carinii.

Journal: Antimicrobial agents and chemotherapy 20011201

Title: Variations of ferritin levels over a period of 15 years as a compliance chelation index in thalassemic patients.

Journal: American journal of hematology 20011201

Title: Assessment of antimalarial effect of ICL670A on in vitro cultures of Plasmodium falciparum.

Journal: British journal of haematology 20011201

Title: Sinusoidal endothelial cell injury by superoxide anion and iron in the Propionibacterium acnes-pretreated and lipopolysaccharide-stimulated rat liver.

Journal: Liver 20011201

Title: Hypoxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis.

Journal: The Journal of biological chemistry 20011130

Title: Overexpression of heme oxygenase protects renal tubular cells against cold storage injury: studies using hemin induction and HO-1 gene transfer.

Journal: Transplantation 20011115

Title: Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide.

Journal: Cancer research 20011115

Title: Optimization of the lariat ether carboxylic acid host structure for ferrioxamine B: demonstration of a second coordination shell chelate effect.

Journal: Inorganic chemistry 20011105

Title: Entry, half-life, and desferrioxamine-accelerated clearance of brain aluminum after a single (26)Al exposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20011101

Title: Intussusception due to Yersinia enterocolitica enterocolitis in a patient with beta-thalassemia.

Journal: Archives of pathology & laboratory medicine 20011101

Title: Practical management of iron overload.

Journal: British journal of haematology 20011101

Title: Inhibition of malignant cell growth by 311, a novel iron chelator of the pyridoxal isonicotinoyl hydrazone class: effect on the R2 subunit of ribonucleotide reductase.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20011101

Title: Differential expression of adrenomedullin and its receptor component, receptor activity modifying protein (RAMP) 2 during hypoxia in cultured human neuroblastoma cells.

Journal: Peptides 20011101

Title: The effect of an iron supplement on serum aluminum level and desferrioxamine mobilization test in hemodialysis patients.

Journal: Renal failure 20011101

Title: Haem metabolic aspects on nitric oxide formation in endotoxaemia.

Journal: Pharmacology & toxicology 20011101

Title: Regulation of the hypoxia-inducible factor 1alpha by the inflammatory mediators nitric oxide and tumor necrosis factor-alpha in contrast to desferroxamine and phenylarsine oxide.

Journal: The Journal of biological chemistry 20011026

Title: An IRP-like protein from Plasmodium falciparum binds to a mammalian iron-responsive element.

Journal: Blood 20011015

Title: Use of SDS micelles to stabilize a ternary intermediate in the reaction of ferrioxamine B and 1,10-phenanthroline.

Journal: Inorganic chemistry 20011008

Title: Ischemia-reperfusion injury of the cochlea: effects of an iron chelator and nitric oxide synthase inhibitors.

Journal: Hearing research 20011001

Title: Role of free radicals in the toxicity of airborne fine particulate matter.

Journal: Chemical research in toxicology 20011001

Title: Vineberg procedure combined with therapeutic angiogenesis: old wine in a new bottle.

Journal: The Annals of thoracic surgery 20011001

Title: Chelation therapy in beta-thalassemia: an optimistic update.

Journal: Seminars in hematology 20011001

Title: Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrioxamine (desferoxamine) in rat liver homogenates.

Journal: The Journal of pharmacy and pharmacology 20011001

Title: Crystal structure of ferrioxamine B: a comparative analysis and implications for molecular recognition.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20011001

Title: [Iron overload and myelodysplastic syndromes].

Journal: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20011001

Title: [Relationship between dopamine and iron contents in the brain of parkinsonian rats].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20011001

Title: Long-term administration of high-dose deferoxamine 2 days per week in thalassemic patients.

Journal: European journal of haematology 20011001

Title: Modulation of oxidative events by multivalent manganese complexes in brain tissue.

Journal: Free radical biology & medicine 20010915

Title: In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies.

Journal: The American journal of pathology 20010901

Title: Cutaneous hyperpigmentation following venous sclerotherapy treated with deferoxamine mesylate.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20010901

Title: A study on the role of nitric oxide and iron in 3-morpholino-sydnonimine-induced increases in dopamine release in the striatum of freely moving rats.

Journal: British journal of pharmacology 20010901

Title: Stress proteins in oligodendrocytes: differential effects of heat shock and oxidative stress.

Journal: Journal of neurochemistry 20010901

Title: Suppression of Ca2+ influx through L-type voltage-dependent calcium channels by hydroxyl radical in mouse cerebral cortical neurons.

Journal: Brain research. Molecular brain research 20010815

Title: Mechanism of metal-mediated DNA damage induced by metabolites of carcinogenic 2-nitropropane.

Journal: Mutation research 20010808

Title: S-nitrosothiols do not induce oxidative stress, contrary to other nitric oxide donors, in cultures of vascular endothelial or smooth muscle cells.

Journal: European journal of pharmacology 20010803

Title: Involvement of PLAGL2 in activation of iron deficient- and hypoxia-induced gene expression in mouse cell lines.

Journal: Oncogene 20010802

Title: Redox metal chelation ameliorates radiation-induced bone marrow toxicity in a mouse model.

Journal: Radiation research 20010801

Title: Physiological amounts of ascorbate potentiate phorbol ester-induced nuclear-binding of AP-1 transcription factor in cells of macrophagic lineage.

Journal: Free radical biology & medicine 20010801

Title: Iron inhibits the nitric oxide synthesis elicited by asbestos in murine macrophages.

Journal: Free radical biology & medicine 20010801

Title: The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: The mechanisms involved in inhibiting cell-cycle progression.

Journal: Blood 20010801

Title: Exploring the 'iron shuttle' hypothesis in chelation therapy: effects of combined deferoxamine and deferiprone treatment in hypertransfused rats with labeled iron stores and in iron-loaded rat heart cells in culture.

Journal: The Journal of laboratory and clinical medicine 20010801

Title: Association of phlebotomy and subcutaneous bolus injection of deferoxamine for the treatment of anemic patients with iron overload.

Journal: Haematologica 20010801

Title: Electrospray ionisation-mass spectrometry of hydroxamate siderophores.

Journal: The Analyst 20010801

Title: Involvement of nitric oxide in killing of Schistosoma mansoni sporocysts by hemocytes from resistant Biomphalaria glabrata.

Journal: The Journal of parasitology 20010801

Title: [Inhibition of iron-catalyzed oxidative reactions restores mathcing between coronary blood flow and myocardial metabolic demand in type 2 diabetes].

Journal: Archives des maladies du coeur et des vaisseaux 20010801

Title: Protection of outer hair cells from reperfusion injury by an iron chelator and a nitric oxide synthase inhibitor in the guinea pig cochlea.

Journal: Neuroscience letters 20010706

Title: Cisplatin ototoxicity: involvement of iron and enhanced formation of superoxide anion radicals.

Journal: Toxicology and applied pharmacology 20010701

Title: Deferoxamine-induced dysplasia of the knee: sonographic features and diagnostic performance compared with magnetic resonance imaging.

Journal: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 20010701

Title: Effects of deferoxamine on tissue superoxide dismutase and glutathione peroxidase levels in experimental head trauma.

Journal: The Journal of trauma 20010701

Title: Iron metabolism, free radicals, and oxidative injury.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20010701

Title: Deferoxamine toxicity in hepatoma and primary rat cortical brain cultures.

Journal: Human & experimental toxicology 20010701

Title: Comparison between deferoxamine and deferiprone (L1) in iron-loaded thalassemia patients.

Journal: European journal of haematology 20010701

Title: Linear growth in homozygous beta-thalassemia and beta-thalassemia/hemoglobin E patients under different treatment regimens.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20010701

Title: Iron chelation improves endothelial function in patients with coronary artery disease.

Journal: Circulation 20010612

Title: Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms.

Journal: The Journal of biological chemistry 20010601

Title: The push-and-pull mechanism to scavenge redox-active transition metals: a novel concept in myocardial protection.

Journal: The Journal of thoracic and cardiovascular surgery 20010601

Title: Kupffer cells and neutrophils as paracrine regulators of the heme oxygenase-1 gene in hepatocytes after hemorrhagic shock.

Journal: Shock (Augusta, Ga.) 20010601

Title: [Pregnancy in women with thalassaemia].

Journal: Minerva ginecologica 20010601

Title: Selective pick-up of increased iron by deferoxamine-coupled cellulose abrogates the iron-driven induction of matrix-degrading metalloproteinase 1 and lipid peroxidation in human dermal fibroblasts in vitro: a new dressing concept.

Journal: The Journal of investigative dermatology 20010601

Title: 3,4-Dichlorophenylhydroxylamine cytotoxicity in renal cortical slices from Fischer 344 rats.

Journal: Toxicology 20010521

Title: Hypoxia induces lytic replication of Kaposi sarcoma-associated herpesvirus.

Journal: Blood 20010515

Title: Determination of a new oral iron chelator, ICL670, and its iron complex in plasma by high-performance liquid chromatography and ultraviolet detection.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010505

Title: Regulatory interactions between iron and nitric oxide metabolism for immune defense against Plasmodium falciparum infection.

Journal: The Journal of infectious diseases 20010501

Title: Cellular titration of apoptosis with steady state concentrations of H(2)O(2): submicromolar levels of H(2)O(2) induce apoptosis through Fenton chemistry independent of the cellular thiol state.

Journal: Free radical biology & medicine 20010501

Title: Primary breast lymphoma detected with Tc-99m tetrofosmin scintigraphy.

Journal: Clinical nuclear medicine 20010501

Title: A case of malignant lymphoma with testis involvement detected by Ga-67 scan.

Journal: Clinical nuclear medicine 20010501

Title: Tc-99m MDP and Ga-67 citrate scintigraphic findings in sarcoidosis with osseous involvement.

Journal: Clinical nuclear medicine 20010501

Title: The controversial role of deferiprone in the treatment of thalassemia.

Journal: The Journal of laboratory and clinical medicine 20010501

Title: Evaluation of a new selective medium for methicillin-resistant Staphyloccocus aureus.

Journal: Journal of medical microbiology 20010501

Title: Reaction of oxygen with 6-hydroxydopamine catalyzed by Cu, Fe, Mn, and V complexes: identification of a thermodynamic window for effective metal catalysis.

Journal: Archives of biochemistry and biophysics 20010501

Title: Effects of an extracellular metal chelator on neurovascular function in diabetic rats.

Journal: Diabetologia 20010501

Title: [Therapeuetic management of patients with thalassemia major].

Journal: Bulletin de la Societe de pathologie exotique (1990) 20010501

Title: mRNA localization by a 145-nucleotide region of the c-fos 3'--untranslated region. Links to translation but not stability.

Journal: The Journal of biological chemistry 20010427

Title: Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.

Journal: Science (New York, N.Y.) 20010420

Title: HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.

Journal: Science (New York, N.Y.) 20010420

Title: A new molecular role for iron in regulation of cell cycling and differentiation of HL-60 human leukemia cells: iron is required for transcription of p21(WAF1/CIP1) in cells induced by phorbol myristate acetate.

Journal: Journal of cellular physiology 20010401

Title: Yersinia enterocolitica as a cause of intra-abdominal abscess: the role of iron.

Journal: Canadian journal of surgery. Journal canadien de chirurgie 20010401

Title: Persistence of delayed adrenarche in boys with thalassemia.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20010401

Title: Pretreatment of guinea-pigs with iron or desferal influences the course of Yersinia enterocolitica infections.

Journal: Journal of veterinary medicine. B, Infectious diseases and veterinary public health 20010401

Title: The role of the FRE family of plasma membrane reductases in the uptake of siderophore-iron in Saccharomyces cerevisiae.

Journal: The Journal of biological chemistry 20010330

Title: Atherosclerosis: defeat of the defense?

Journal: Circulation research 20010316

Title: Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice.

Journal: Circulation research 20010316

Title: Enterobactin: the characteristic catecholate siderophore of Enterobacteriaceae is produced by Streptomyces species.(1).

Journal: FEMS microbiology letters 20010315

Title: Mitochondrial involvement in cocaine-treated rat hepatocytes: effect of N-acetylcysteine and deferoxamine.

Journal: British journal of pharmacology 20010301

Title: Influence of iron restriction on Chlamydia pneumoniae and C. trachomatis.

Journal: Journal of medical microbiology 20010301

Title: Role of the epithelium in opposing H(2)O(2)-induced modulation of acetylcholine-induced contractions in rabbit intrapulmonary bronchiole.

Journal: British journal of pharmacology 20010301

Title: Hemoproteins affect H(2)O(2) removal from rat tissues.

Journal: The international journal of biochemistry & cell biology 20010301

Title: Rapid recovery with oral zinc sulphate in deferoxamine-induced presumed optic neuropathy and hearing loss.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20010301

Title: Pharmacosurveillance and quality of care of thalassaemic patients. A large scale epidemiological survey.

Journal: European journal of clinical pharmacology 20010301

Title: The preventive role of deferoxamine against acute doxorubicin-induced cardiac, renal and hepatic toxicity in rats.

Journal: Pharmacological research 20010301

Title: Effects of aminoguanidine and desferrioxamine on some vascular and biochemical changes associated with streptozotocin-induced hyperglycaemia in rats.

Journal: Pharmacological research 20010301

Title: Evaluation of cerebral vasospasm with transcranial magnetic stimulation: an experimental study.

Journal: Clinical and experimental medicine 20010301

Title: Cytochrome b(5) plays a key role in human microsomal chromium(VI) reduction.

Journal: Toxicology 20010227

Title: Desferrioxamine, an iron chelator, upregulates cyclooxygenase-2 expression and prostaglandin production in a human macrophage cell line.

Journal: Biochimica et biophysica acta 20010226

Title: Comparative effects of metal chelating agents on the neuronal cytotoxicity induced by copper (Cu+2), iron (Fe+3) and zinc in the hippocampus.

Journal: Brain research 20010216

Title: Accumulation of HIF-1alpha under the influence of nitric oxide.

Journal: Blood 20010215

Title: ICL670A: a new synthetic oral chelator: evaluation in hypertransfused rats with selective radioiron probes of hepatocellular and reticuloendothelial iron stores and in iron-loaded rat heart cells in culture.

Journal: Blood 20010215

Title: Redox-active iron mediates amyloid-beta toxicity.

Journal: Free radical biology & medicine 20010215

Title: Oxygen radicals mediate the final exacerbation of endothelin-1-induced gastric ulcer in rat.

Journal: European journal of pharmacology 20010209

Title: Desferrioxamine-chelatable iron, a component of serum non-transferrin-bound iron, used for assessing chelation therapy.

Journal: Blood 20010201

Title: DNA-protein crosslinks induced by nickel compounds in isolated rat lymphocytes: role of reactive oxygen species and specific amino acids.

Journal: Toxicology and applied pharmacology 20010201

Title: Coexistence of zinc and iron augmented oxidative injuries in the nigrostriatal dopaminergic system of SD rats.

Journal: Free radical biology & medicine 20010201

Title: 6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation.

Journal: Free radical biology & medicine 20010201

Title: Iron status and the outcome of HIV infection: an overview.

Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20010201

Title: Radiation sensitization of mammalian cells by metal chelators.

Journal: Radiation research 20010201

Title: Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation--a potential mechanism.

Journal: European journal of immunology 20010201

Title: Carbon monoxide is the heme oxygenase product with a pyretic action: evidence for a cGMP signaling pathway.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010201

Title: Incomplete cerebral infarctions are not silent.

Journal: Journal of pediatric hematology/oncology 20010201

Title: Inhibition of N-myc expression and induction of apoptosis by iron chelation in human neuroblastoma cells.

Journal: Cancer research 20010201

Title: Lucigenin chemiluminescence in human seminal plasma.

Journal: Free radical research 20010201

Title: Effect of pre-loading oral glucosamine HCl/chondroitin sulfate/manganese ascorbate combination on experimental arthritis in rats.

Journal: Experimental biology and medicine (Maywood, N.J.) 20010201

Title: Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells.

Journal: FEBS letters 20010119

Title: Impairment of endothelial nitric oxide production by acute glucose overload.

Journal: American journal of physiology. Endocrinology and metabolism 20010101

Title: Reactive oxygen and nitrogen metabolites modulate fibronectin-induced fibroblast migration in vitro.

Journal: Free radical biology & medicine 20010101

Title: Detection of dichromate (VI)-induced DNA strand breaks and formation of paramagnetic chromium in multiple mouse organs.

Journal: Toxicology and applied pharmacology 20010101

Title: Progression of iron overload in sickle cell disease.

Journal: Seminars in hematology 20010101

Title: Deferoxamine pharmacokinetics.

Journal: Seminars in hematology 20010101

Title: Improving adherence with deferoxamine regimens for patients receiving chronic transfusion therapy.

Journal: Seminars in hematology 20010101

Title: Lazaroid compounds prevent early but not late stages of oxidant-induced cell injury: potential explanation for the lack of efficacy of lazaroids in clinical trials.

Journal: Pharmacological research 20010101

Title: Inhibition of hepatitis B virus production associated with high levels of intracellular viral DNA intermediates in iron-depleted HepG2.2.15 cells.

Journal: Journal of hepatology 20010101

Title: Electron paramagnetic resonance detection of free radicals in UV-irradiated human and mouse skin.

Journal: Current problems in dermatology 20010101

Title: Oxidative insult in sheep red blood cells induced by T-butyl hydroperoxide: the roles of glutathione and glutathione peroxidase.

Journal: Free radical research 20010101

Title: The role of oxygen-derived free radicals in augmented relaxations to levcromakalim in the aorta from hypertensive rats.

Journal: Japanese journal of pharmacology 20010101

Title: Temporary treatment with sirolimus and low-trough cyclosporine prevents acute islet allograft rejection, and combination with starch-conjugated deferoxamine promotes islet engraftment in the preclinical pig model.

Journal: Transplantation proceedings 20010101

Title: Klebsiella pneumoniae meningitis in thalassemia major patients.

Journal: Pediatric hematology and oncology 20010101

Title: Selenium and glutathione peroxidase with beta-thalassemia major.

Journal: Nursing research 20010101

Title: [Aluminum and uremic bone disease. Diagnostic utility of serum aluminum and the deferoxamine (DFO) test ].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20010101

Title: Inhibition of growth of human breast carcinoma cells by an antisense oligonucleotide targeted to the transferrin receptor gene.

Journal: Anticancer research 20010101

Title: [Effects of aluminum and deferoxamine on concentration of essential elements in animals experimentally intoxicated with aluminum].

Journal: Medycyna doswiadczalna i mikrobiologia 20010101

Title: Alpha-lipoic acid and alpha-lipoamide prevent oxidant-induced lysosomal rupture and apoptosis.

Journal: Redox report : communications in free radical research 20010101

Title: Bone aluminum uptake in uremic rats receiving intraperitoneal iron.

Journal: Biological trace element research 20010101

Title: Increased plasma levels of interleukin-6 and interleukin-8 in beta-thalassaemia major.

Journal: Haematologia 20010101

Title: The desferrithiocin (DFT) class of iron chelators: potential as antineoplastic agents.

Journal: Anti-cancer drug design 20010101

Title: [Hereditary hemochromatosis].

Journal: Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru 20010101

Title: Comparing qualitative and quantitative spectroscopic techniques for the detection of the effect of direct iron loading of mammalian cell cultures.

Journal: Methods in cell science : an official journal of the Society for In Vitro Biology 20010101

Title: Differential cellular regulation of the mitochondrial permeability transition in an in vitro model of 1,3-dinitrobenzene-induced encephalopathy.

Journal: Brain research 20000825

Title: Glutathione oxidation and PTPase inhibition by hydrogen peroxide in Caco-2 cell monolayer.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20000801

Title: Inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-stimulated Cyp1a1 promoter activity by hypoxic agents.

Journal: Biochemical pharmacology 20000615

Title: Repression of heme oxygenase-1 by hypoxia in vascular endothelial cells.

Journal: Biochemical and biophysical research communications 20000519

Title: Nitric oxide inhibits dioxin action for the stimulation of Cyp1a1 promoter activity.

Journal: Biological & pharmaceutical bulletin 20000501

Title: In vitro cleavage by asbestos fibers of the fifth component of human complement through free-radical generation and kallikrein activation.

Journal: Journal of toxicology and environmental health. Part A 20000414

Title: Erythropoietin induction in Hep3B cells is not affected by inhibition of heme biosynthesis.

Journal: Biochimica et biophysica acta 20000227

Title: Inhibition of human immunodeficiency virus type 1 replication in human mononuclear blood cells by the iron chelators deferoxamine, deferiprone, and bleomycin.

Journal: The Journal of infectious diseases 20000201

Title: Mechanisms of GM-CSF increase by diesel exhaust particles in human airway epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20000101

Title: Role of molecular oxygen in the generation of hydroxyl and superoxide anion radicals during enzymatic Cr(VI) reduction and its implication to Cr(VI)-induced carcinogenesis.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20000101

Title: Comparison of IY81149 with omeprazole in rat reflux oesophagitis.

Journal: Journal of autonomic pharmacology 20000101

Title: Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19991115

Title: Effects of pro- and antioxidative compounds on renal production of erythropoietin.

Journal: Endocrinology 19990201

Title: Effect of microbial siderophores on matrix metalloproteinase-2 activity.

Journal: Journal of periodontal research 19990101

Title: Differential regulation of human alveolar macrophage-derived interleukin-1beta and tumor necrosis factor-alpha by iron.

Journal: The Journal of laboratory and clinical medicine 19981201

Title: Involvement of a local fenton reaction in the reciprocal modulation by O2 of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene and the insulin-dependent activation of the glucokinase gene in rat hepatocytes.

Journal: The Biochemical journal 19981015

Title: A trial to investigate the relationship between DFO pharmacokinetics and metabolism and DFO-related toxicity.

Journal: Annals of the New York Academy of Sciences 19980630

Title: Increase of reactive oxygen species (ROS) in endothelial cells by shear flow and involvement of ROS in shear-induced c-fos expression.

Journal: Journal of cellular physiology 19980501

Title: Apparent role of hydroxyl radicals in oxidative brain injury induced by sodium nitroprusside.

Journal: Free radical biology & medicine 19980501

Title: Hypoxic regulation of endothelial glyceraldehyde-3-phosphate dehydrogenase.

Journal: The American journal of physiology 19980201

Title: Role of H2O2 and heme-containing O2 sensors in hypoxic regulation of tyrosine hydroxylase gene expression.

Journal: The American journal of physiology 19980101

Title: Cytokine production by human airway epithelial cells after exposure to an air pollution particle is metal-dependent.

Journal: Toxicology and applied pharmacology 19971001

Title: Oxidant stress regulates basal endothelin-1 production by cultured rat pulmonary endothelial cells.

Journal: The American journal of physiology 19971001

Title: Effects of new anticonvulsant medications on porphyrin synthesis in cultured liver cells: potential implications for patients with acute porphyria.

Journal: Neurology 19970701

Title: Desferrioxamine ototoxicity in an adult transfusion-dependent population.

Journal: The Journal of otolaryngology 19970401

Title: Alterations in intracellular reactive oxygen species generation and redox potential modulate mast cell function.

Journal: European journal of immunology 19970101

Title: Sensorimotor neurotoxicity associated with high-dose deferoxamine treatment.

Journal: Journal of pediatric hematology/oncology 19970101

Title: [A role for reactive oxygen species in the pathogenesis of focal glomerulosclerosis].

Journal: Nihon Jinzo Gakkai shi 19961101

Title: The mitogenic effect of H2O2 for vascular smooth muscle cells is mediated by an increase of the affinity of basic fibroblast growth factor for its receptor.

Journal: FEBS letters 19961014

Title: In vitro inhibition of human cytomegalovirus replication by calcium trinatrium diethylenetriaminepentaacetic acid.

Journal: Antiviral research 19960601

Title: Sensorineural hearing loss in children with thalassemia major in Northern Greece.

Journal: International journal of pediatric otorhinolaryngology 19960501

Title: Role of 'catalytic' iron in an animal model of minimal change nephrotic syndrome.

Journal: Kidney international 19960201

Title: Risks of parenteral deferoxamine for acute iron poisoning.

Journal: Journal of toxicology. Clinical toxicology 19960101

Title: Clinically achievable plasma deferoxamine concentrations eliminate Pneumocystis carinii trophozoites in a rat model.

Journal: The Journal of eukaryotic microbiology 19960101

Title: Myasthenia gravis following iron chelation therapy with intravenous desferrioxamine.

Journal: European journal of haematology 19950801

Title: High susceptibility to paraquat-driven lipid peroxidation of cultured hepatocytes loaded with linolenic acid.

Journal: The Journal of pharmacology and experimental therapeutics 19950701

Title: [Ocular findings in Desferal therapy].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 19950201

Title: In vitro inhibition of human cytomegalovirus replication by desferrioxamine.

Journal: Antiviral research 19940901

Title: Deferoxamine-associated retinopathy after subcutaneous injection.

Journal: American journal of ophthalmology 19940815

Title: Early detection of nephrotoxic effects in thalassemic patients receiving desferrioxamine therapy.

Journal: Kidney international 19940801

Title: Reactive oxygen metabolite-induced toxicity to cultured bovine endothelial cells: status of cellular iron in mediating injury.

Journal: Journal of cellular physiology 19940701

Title: Iron chelators as therapeutic agents against Pneumocystis carinii.

Journal: Antimicrobial agents and chemotherapy 19940501

Title: Effect of acute hypertension in the coronary circulation: role of mechanical factors and oxygen radicals.

Journal: Journal of hypertension 19940201

Title: Comparison of the protective effects of desferrioxamine and ICRF-187 against doxorubicin-induced toxicity in spontaneously hypertensive rats.

Journal: Cancer chemotherapy and pharmacology 19940101

Title: Effect of deferoxamine on retinal lipid peroxidation in experimental uveitis.

Journal: Investigative ophthalmology & visual science 19931001

Title: Molecular mechanisms of nitrofurantoin-induced hepatocyte toxicity in aerobic versus hypoxic conditions.

Journal: Archives of biochemistry and biophysics 19930901

Title: Deferoxamine prevents lipid peroxidation and attenuates reoxygenation injury in postischemic skeletal muscle.

Journal: The American journal of physiology 19930601

Title: [Acute hepatitis induced by deferoxamine in a patient under chronic hemodialysis].

Journal: Therapie 19921101

Title: Dehydrogenase conversion to oxidase and lipid peroxidation in brain after carbon monoxide poisoning.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 19921001

Title: Role of iron in oxidative stress in skeletal muscle atrophied by immobilization.

Journal: Pflugers Archiv : European journal of physiology 19920601

Title: Hematoma-induced flap necrosis and free radical scavengers.

Journal: Archives of otolaryngology--head & neck surgery 19920501

Title: Iron chelation in myocardial preservation after ischemia-reperfusion injury: the importance of pretreatment and toxicity.

Journal: The Annals of thoracic surgery 19920301

Title: Acute renal failure occurring during intravenous desferrioxamine therapy: recovery after haemodialysis.

Journal: Haematologica 19920101

Title: Roles of active oxygen species in glomerular epithelial cell injury in vitro caused by puromycin aminonucleoside.

Journal: Toxicology 19920101

Title: [Ototoxicity of deferoxamine].

Journal: Anales otorrinolaringologicos ibero-americanos 19920101

Title: Role of oxygen-derived free radicals in indomethacin-induced gastric injury.

Journal: The American journal of physiology 19910901

Title: Desferrioxamine and HIV.

Journal: Lancet (London, England) 19910601

Title: Neurophysiological and neuro-otological study of homozygous beta-thalassemia under long-term desferrioxamine (DFO) treatment.

Journal: Acta neurologica Scandinavica 19910501

Title: Hearing impairment during deferoxamine therapy for thalassemia major.

Journal: The Journal of pediatrics 19910501

Title: Inhibition by desferrioxamine of in-vitro replication of HIV-1.

Journal: Lancet (London, England) 19910330

Title: Suppressive effect of deferoxamine on the growth of Pneumocystis carinii in vitro.

Journal: The Journal of protozoology 19910101

Title: Iron chelation by deferoxamine inhibits lipid peroxidation during cardiopulmonary bypass in humans.

Journal: Circulation 19901101

Title: Iron release and erythrocyte damage in allyl alcohol intoxication in mice.

Journal: Biochemical pharmacology 19901001

Title: Deferoxamine and eflornithine (DL-alpha-difluoromethylornithine) in a rat model of Pneumocystis carinii pneumonia.

Journal: Antimicrobial agents and chemotherapy 19900901

Title: Toxic effects associated with the administration of deferoxamine in the premature baboon with hyaline membrane disease.

Journal: American journal of diseases of children (1960) 19900801

Title: Vision and hearing during deferoxamine therapy.

Journal: The Journal of pediatrics 19900801

Title: Cerebrospinal fluid aluminum levels following deferoxamine.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 19900801

Title: Comparison of deferoxamine pharmacokinetics between asymptomatic thalassemic children and those exhibiting severe neurotoxicity.

Journal: Clinical pharmacology and therapeutics 19900401

Title: Herpes simplex virus type 1 ribonucleotide reductase: selective and synergistic inactivation by A1110U and its iron complex.

Journal: Biochemical pharmacology 19900215

Title: Acute visual disorders in patients on regular dialysis given desferrioxamine as a test.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19900101

Title: Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine.

Journal: Nephron 19900101

Title: Acute bone marrow aplasia associated with intravenous administration of deferoxamine (desferrioxamine).

Journal: Drug safety 19900101

Title: Deferoxamine decreases necrosis in dorsally based pig skin flaps.

Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 19891101

Title: Desferrioxamine ototoxicity: evaluation of risk factors in thalassaemic patients and guidelines for safe dosage.

Journal: British journal of haematology 19891101

Title: [Auditory, visual and neurologic toxicity of deferoxamine].

Journal: Revista medica de Chile 19890501

Title: Exacerbation of aluminium encephalopathy after treatment with desferrioxamine.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19890101

Title: Exacerbation of aluminium encephalopathy after treatment with desferrioxamine.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19890101

Title: [Ototoxicity of desferrioxamine in hemodialyzed patients].

Journal: Acta otorrinolaringologica espanola 19890101

Title: Irreversible ocular toxicity from single 'challenge' dose of deferoxamine.

Journal: Clinical nephrology 19890101

Title: Ocular toxicity of desferrioxamine--an example of copper promoted auto-oxidative damage?

Journal: The British journal of ophthalmology 19890101

Title: Reversal of desferrioxamine induced auditory neurotoxicity during treatment with Ca-DTPA.

Journal: Archives of disease in childhood 19890101

Title: Evidence suggesting a role for hydroxyl radical in puromycin aminonucleoside-induced proteinuria.

Journal: Kidney international 19881001

Title: Oxidative cell injury in the killing of cultured hepatocytes by allyl alcohol.

Journal: Archives of biochemistry and biophysics 19880901

Title: Precipitation of dialysis dementia by deferoxamine treatment of aluminum-related bone disease.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 19880801

Title: Hearing loss attributed to desferrioxamine in patients with beta-thalassaemia major.

Journal: The Medical journal of Australia 19880620

Title: Acute visual and auditory neurotoxicity in patients with end-stage renal disease receiving desferrioxamine.

Journal: Clinical nephrology 19880401

Title: Evidence suggesting a role for hydroxyl radical in gentamicin-induced acute renal failure in rats.

Journal: The Journal of clinical investigation 19880201

Title: Grand mal fitting in a patient on regular haemodialysis treatment and receiving desferrioxamine therapy.

Journal: Scandinavian journal of urology and nephrology 19880101

Title: Deferoxamine (Desferal)-induced ocular toxicity.

Journal: Pediatric hematology and oncology 19880101

Title: Hearing loss and desferrioxamine in homozygous beta-thalassemia.

Journal: Audiology : official organ of the International Society of Audiology 19880101

Title: [Audiologic evaluation of patients with thalassemic syndromes treated with desferrioxamine B].

Journal: La Pediatria medica e chirurgica : Medical and surgical pediatrics 19880101

Title: Desferrioxamine-induced acute neurosensorial deafness.

Journal: Nephron 19880101

Title: Serial studies of auditory neurotoxicity in patients receiving deferoxamine therapy.

Journal: The American journal of medicine 19871201

Title: Hearing loss attributed to desferrioxamine in patients with beta-thalassaemia major.

Journal: The Medical journal of Australia 19870817

Title: Deferoxamine (DFO): the effectiveness for noninvasive diagnosis of aluminum-related bone disease, and for treatment of the disease.

Journal: Journal of UOEH 19870320

Title: Microcytic anemia in dialysis patients: reversible marker of aluminum toxicity.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 19870301

Title: [Severe ocular toxicity of desferrioxamine in the hemodialyzed patient].

Journal: Nephrologie 19870101

Title: Ocular toxicity after a single intravenous dose of desferrioxamine in 2 hemodialyzed patients.

Journal: Nephron 19870101

Title: Deferoxamine improves left ventricular function in beta-thalassemia.

Journal: Archives of internal medicine 19861201

Title: Visual and auditory neurotoxicity in patients receiving subcutaneous deferoxamine infusions.

Journal: The New England journal of medicine 19860403

Title: [Evaluation of auditory function in homozygous beta-thalassemia].

Journal: La Pediatria medica e chirurgica : Medical and surgical pediatrics 19860101

Title: Thrombocytopenia associated with intravenous desferrioxamine.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 19851001

Title: Acute deafness and desferrioxamine.

Journal: Lancet (London, England) 19850706

Title: Cerebral and ocular toxicity induced by desferrioxamine.

Journal: The Quarterly journal of medicine 19850701

Title: Ocular and auditory toxicity of long-term, high-dose subcutaneous deferoxamine therapy.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 19850601

Title: Ocular toxicity of desferrioxamine.

Journal: Lancet (London, England) 19850406

Title: Deferoxamine (Desferal)-induced toxic retinal pigmentary degeneration and presumed optic neuropathy.

Journal: Ophthalmology 19840501

Title: Visual loss in patient on high-dose subcutaneous desferrioxamine.

Journal: Lancet (London, England) 19840324

Title: Desferrioxamine, ocular toxicity, and trace metals.

Journal: Lancet (London, England) 19830827

Title: Ocular toxicity of high-dose intravenous desferrioxamine.

Journal: Lancet (London, England) 19830723

Title: Effect of a specific iron chelating agent on animal models of inflammation.

Journal: Annals of the rheumatic diseases 19830201

Title: Reduction in severity of physical dependence on ethanol in mice caused by desferrioxamine administration.

Journal: Pharmacology, biochemistry, and behavior 19830101

Title: Tinnitus in a patient with beta-thalassaemia intermedia on long-term treatment with desferrioxamine.

Journal: Postgraduate medical journal 19810901

Title: [The echocardiography in thalassemia major (author's transl)].

Journal: La Pediatria medica e chirurgica : Medical and surgical pediatrics 19810101

Title: Acute renal insufficiency occurring during intravenous desferrioxamine therapy.

Journal: Scandinavian journal of haematology 19790301

Title: Iron poisoning in children.

Journal: Clinical toxicology 19750101

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Tags:138-14-7 Molecular Formula|138-14-7 MDL|138-14-7 SMILES|138-14-7 Deferoxamine mesylate