Home Other Building Blocks 1380672-07-0
1380672-07-0,MFCD28167833
Catalog No.:AA0017UW

1380672-07-0 | G007-LK

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$18.00   $13.00
- +
2mg
98+%
in stock  
$26.00   $18.00
- +
5mg
98+%
in stock  
$44.00   $31.00
- +
10mg
98+%
in stock  
$65.00   $46.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0017UW
Chemical Name:
G007-LK
CAS Number:
1380672-07-0
Molecular Formula:
C25H16ClN7O3S
Molecular Weight:
529.9576
MDL Number:
MFCD28167833
SMILES:
N#Cc1ccc(cc1)c1nnc(o1)/C=C/c1nnc(n1c1ccccc1Cl)c1ccc(cn1)S(=O)(=O)C
Properties
Computed Properties
 
Complexity:
961  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
9  
Rotatable Bond Count:
6  
XLogP3:
3.1  

Literature

Title: Use of cardioactive drugs in acute myocardial infarction.

Journal: Heart & lung : the journal of critical care 19760101

Title: Voronkov A, et al. Structural basis and SAR for G007-LK, a lead stage 1,2,4-triazole based specific tankyrase 1/2 inhibitor. J Med Chem. 2013 Apr 11;56(7):3012-23.

Title: Norum JH, et al. The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology. Biol Res. 2018 Jan 9;51(1):3.

Title: Xin Chen, et al. Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade. PLoS One. 2017 Sep 6;12(9):e0184068.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1380672-07-0
Tags:1380672-07-0 Molecular Formula|1380672-07-0 MDL|1380672-07-0 SMILES|1380672-07-0 G007-LK