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138977-28-3,MFCD00153778
Catalog No.:AA0019W4

138977-28-3 | Capsazepine

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Purity
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1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
98%
in stock  
$52.00   $36.00
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10mg
98%
in stock  
$80.00   $56.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0019W4
Chemical Name:
Capsazepine
CAS Number:
138977-28-3
Molecular Formula:
C19H21ClN2O2S
Molecular Weight:
376.9002
MDL Number:
MFCD00153778
SMILES:
Clc1ccc(cc1)CCNC(=S)N1CCCc2c(C1)cc(O)c(c2)O
Properties
Computed Properties
 
Complexity:
445  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
3.9  

Downstream Synthesis Route

[1]Walpole,ChristopherS.J.;Bevan,Stuart;Bovermann,Guenter;Boelsterli,JohannJ.;Breckenridge,Robin;etal.[JournalofMedicinalChemistry,1994,vol.37,#13,p.1942-1954]

[2]Dalence-Guzman,MariaF.;Berglund,Magnus;Skogvall,Staffan;Sterner,Olov[BioorganicandMedicinalChemistry,2008,vol.16,#5,p.2499-2512]

[3]CurrentPatentAssignee:RESPIRATORIUS-US2005/165004,2005,A1Locationinpatent:Page/Pagecolumn16

[1]Walpole,ChristopherS.J.;Bevan,Stuart;Bovermann,Guenter;Boelsterli,JohannJ.;Breckenridge,Robin;etal.[JournalofMedicinalChemistry,1994,vol.37,#13,p.1942-1954]

[1]Walpole,ChristopherS.J.;Bevan,Stuart;Bovermann,Guenter;Boelsterli,JohannJ.;Breckenridge,Robin;etal.[JournalofMedicinalChemistry,1994,vol.37,#13,p.1942-1954]

Literature

Title: Role of TRPA1 in acute cardiopulmonary toxicity of inhaled acrolein.

Journal: Toxicology and applied pharmacology 20170601

Title: Gastroprotective and ulcer healing effects of hydroethanolic extract of leaves of Caryocar coriaceum: Mechanisms involved in the gastroprotective activity.

Journal: Chemico-biological interactions 20170105

Title: Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2.

Journal: Oncotarget 20160920

Title: α,β-Unsaturated aldehyde pollutant acrolein suppresses cardiomyocyte contractile function: Role of TRPV1 and oxidative stress.

Journal: Environmental toxicology 20150101

Title: Synthesis and pharmacological evaluation of novel N-aryl-3,4-dihydro-1'H-spiro[chromene-2,4'-piperidine]-1'-carboxamides as TRPM8 antagonists.

Journal: Bioorganic & medicinal chemistry 20131101

Title: Peripheral antinociceptive action of mangiferin in mouse models of experimental pain: role of endogenous opioids, K(ATP)-channels and adenosine.

Journal: Pharmacology, biochemistry, and behavior 20130901

Title: Study on TRPV1-mediated mechanism for the hypersecretion of mucus in respiratory inflammation.

Journal: Molecular immunology 20130101

Title: Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice.

Journal: PloS one 20130101

Title: Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats.

Journal: Neuropharmacology 20121201

Title: Transient receptor potential vanilloid subtype 1 contributes to mesencephalic dopaminergic neuronal survival by inhibiting microglia-originated oxidative stress.

Journal: Brain research bulletin 20121101

Title: Role of KATP channels and TRPV1 receptors in hydrogen sulfide-enhanced gastric emptying of liquid in awake mice.

Journal: European journal of pharmacology 20121015

Title: Protection of ghrelin postconditioning on hypoxia/reoxygenation in gastric epithelial cells.

Journal: World journal of gastroenterology 20121014

Title: Using novel in vitro NociOcular assay based on TRPV1 channel activation for prediction of eye sting potential of baby shampoos.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20121001

Title: Acute myocardial infarction inhibits the neurogenic tachycardic and vasopressor response in rats via presynaptic cannabinoid type 1 receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20121001

Title: Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery.

Journal: Pharmacological research 20120901

Title: Proton-gated ion channels in mouse bone marrow stromal cells.

Journal: Stem cell research 20120901

Title: Involvement of TRPV1 and TRPV4 channels in migration of rat pulmonary arterial smooth muscle cells.

Journal: Pflugers Archiv : European journal of physiology 20120901

Title: N-arachidonoyl-serotonin in the basolateral amygdala increases anxiolytic behavior in the elevated plus maze.

Journal: Behavioural brain research 20120801

Title: TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts.

Journal: Cell calcium 20120801

Title: Disruption of TRPV1-mediated coupling of coronary blood flow to cardiac metabolism in diabetic mice: role of nitric oxide and BK channels.

Journal: American journal of physiology. Heart and circulatory physiology 20120715

Title: Substance P release in response to cardiac ischemia from rat thoracic spinal dorsal horn is mediated by TRPV1.

Journal: Neuroscience 20120712

Title: Capsaicin induces cycle arrest by inhibiting cyclin-dependent-kinase in bladder carcinoma cells.

Journal: International journal of urology : official journal of the Japanese Urological Association 20120701

Title: Capacity of capsazepinoids to relax human small airways and inhibit TLR3-induced TSLP and IFNβ production in diseased bronchial epithelial cells.

Journal: International immunopharmacology 20120701

Title: Extracellular matrix proteoglycan plays a pivotal role in sensitization by low pH of mechanosensitive currents in nociceptive sensory neurones.

Journal: The Journal of physiology 20120701

Title: The transient receptor potential vanilloid receptor 1, TRPV1 (VR1) inhibits peristalsis in the mouse jejunum.

Journal: Archives of Iranian medicine 20120701

Title: Characterization of a novel splice variant of δ ENaC subunit in human lungs.

Journal: American journal of physiology. Lung cellular and molecular physiology 20120615

Title: A possible participation of transient receptor potential vanilloid type 1 channels in the antidepressant effect of fluoxetine.

Journal: European journal of pharmacology 20120615

Title: Enhanced vasorelaxant effects of the endocannabinoid-like mediator, oleamide, in hypertension.

Journal: European journal of pharmacology 20120605

Title: The investigation into indomethacin-induced potentiation of the contractile response to antigen in ovalbumin-sensitized guinea-pig tracheas.

Journal: Fundamental & clinical pharmacology 20120601

Title: Calcium regulation by thermo- and osmosensing transient receptor potential vanilloid channels (TRPVs) in human conjunctival epithelial cells.

Journal: Histochemistry and cell biology 20120601

Title: Involvement of transient receptor potential vanilloid type 1 channels in the pro-convulsant effect of anandamide in pentylenetetrazole-induced seizures.

Journal: Epilepsy research 20120601

Title: Differential role of CB1 and TRPV1 receptors on anandamide modulation of defensive responses induced by nitric oxide in the dorsolateral periaqueductal gray.

Journal: Neuropharmacology 20120601

Title: Ischemic neuroprotection by TRPV1 receptor-induced hypothermia.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120601

Title: Transient receptor potential vanilloid type 1 channels contribute to reflex cutaneous vasodilation in humans.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20120601

Title: Presynaptic enhancement by eugenol of spontaneous excitatory transmission in rat spinal substantia gelatinosa neurons is mediated by transient receptor potential A1 channels.

Journal: Neuroscience 20120517

Title: Acid and stretch, but not capsaicin, are effective stimuli for ATP release in the porcine bladder mucosa: Are ASIC and TRPV1 receptors involved?

Journal: European journal of pharmacology 20120515

Title: Effects of hecogenin and its possible mechanism of action on experimental models of gastric ulcer in mice.

Journal: European journal of pharmacology 20120515

Title: Confocal microscopy with double immunofluorescence staining reveals the functional transient receptor potential vanilloid subtype 1 expressed in myoepithelial cells of human submandibular glands.

Journal: Microscopy research and technique 20120501

Title: Role of TRPV1 in consolidation of fear memories depends on the averseness of the conditioning procedure.

Journal: Neurobiology of learning and memory 20120501

Title: Activation of transient receptor potential vanilloid subtype 1 increases expression and permeability of tight junction in normal and hyposecretory submandibular gland.

Journal: Laboratory investigation; a journal of technical methods and pathology 20120501

Title: Transient receptor potential vanilloid 1 receptors mediate acid-induced mucin secretion via Ca2+ influx in human airway epithelial cells.

Journal: Journal of biochemical and molecular toxicology 20120501

Title: 20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel.

Journal: The Journal of biological chemistry 20120420

Title: Vasorelaxation to capsaicin and its effects on calcium influx in arteries.

Journal: European journal of pharmacology 20120415

Title: Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120401

Title: Endocannabinoid analogues exacerbate marble-burying behavior in mice via TRPV1 receptor.

Journal: Neuropharmacology 20120401

Title: Gastroprotective potential of frutalin, a D-galactose binding lectin, against ethanol-induced gastric lesions.

Journal: Fitoterapia 20120401

Title: Cardiac-specific knockout of ET(A) receptor mitigates low ambient temperature-induced cardiac hypertrophy and contractile dysfunction.

Journal: Journal of molecular cell biology 20120401

Title: Heteromeric heat-sensitive transient receptor potential channels exhibit distinct temperature and chemical response.

Journal: The Journal of biological chemistry 20120302

Title: TRPV1 agonist capsaicin attenuates lung ischemia-reperfusion injury in rabbits.

Journal: The Journal of surgical research 20120301

Title: Gastroprotective effect of Byrsonima sericea DC leaf extract against ethanol-induced gastric injury and its possible mechanisms of action.

Journal: Anais da Academia Brasileira de Ciencias 20120301

Title: [Effects of anandamide on IL-11 production through the TRPV1 of human periodontal ligament cells].

Journal: Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan 20120301

Title: Influence of influenza A infection on capsaicin-induced responses in murine airways.

Journal: The Journal of pharmacology and experimental therapeutics 20120201

Title: Transient receptor potential vanilloid-1 participates in the inhibitory effect of ginsenoside Rg1 on capsaicin-induced interleukin-8 and prostaglandin E2 production in HaCaT cells.

Journal: The Journal of pharmacy and pharmacology 20120201

Title: Use and limitations of three TRPV-1 receptor antagonists on smooth muscles of animals and man: a vote for BCTC.

Journal: European journal of pharmacology 20120105

Title: Beneficial effects of capsiate on ethanol-induced mucosal injury in rats are related to stimulation of calcitonin gene-related Peptide release.

Journal: Planta medica 20120101

Title: Opposing roles for cannabinoid receptor type-1 (CB₁) and transient receptor potential vanilloid type-1 channel (TRPV1) on the modulation of panic-like responses in rats.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120101

Title: Thermo-sensitive transient receptor potential vanilloid channel-1 regulates intracellular calcium and triggers chromogranin A secretion in pancreatic neuroendocrine BON-1 tumor cells.

Journal: Cellular signalling 20120101

Title: Small molecule positive allosteric modulation of TRPV1 activation by vanilloids and acidic pH.

Journal: The Journal of pharmacology and experimental therapeutics 20120101

Title: Peripheral glutamate receptors are required for hyperalgesia induced by capsaicin.

Journal: Pain research and treatment 20120101

Title: ASICs Do Not Play a Role in Maintaining Hyperalgesia Induced by Repeated Intramuscular Acid Injections.

Journal: Pain research and treatment 20120101

Title: Dragon's blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance P in rats.

Journal: Journal of pharmacological sciences 20120101

Title: Activation of TRPV1 by capsaicin induces functional kinin B(1) receptor in rat spinal cord microglia.

Journal: Journal of neuroinflammation 20120101

Title: L type Ca²+ channel blockers prevent oxaliplatin-induced cold hyperalgesia and TRPM8 overexpression in rats.

Journal: Molecular pain 20120101

Title: Anandamide induces sperm release from oviductal epithelia through nitric oxide pathway in bovines.

Journal: PloS one 20120101

Title: The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action.

Journal: BMC cancer 20120101

Title: Anandamide induces endothelium-dependent vasoconstriction and CGRPergic nerve-mediated vasodilatation in the rat mesenteric vascular bed.

Journal: Journal of pharmacological sciences 20120101

Title: Antioncogenic effects of transient receptor potential vanilloid 1 in the progression of transitional urothelial cancer of human bladder.

Journal: ISRN urology 20120101

Title: Capsaicin, a TRPV1 Ligand, Suppresses Bone Resorption by Inhibiting the Prostaglandin E Production of Osteoblasts, and Attenuates the Inflammatory Bone Loss Induced by Lipopolysaccharide.

Journal: ISRN pharmacology 20120101

Title: The Effectiveness of GECB Pastille in Reducing Complications of Dry Socket Syndrome.

Journal: International journal of dentistry 20120101

Title: The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain.

Journal: Molecular pain 20120101

Title: Aberrant TRPV1 expression in heat hyperalgesia associated with trigeminal neuropathic pain.

Journal: International journal of medical sciences 20120101

Title: Antagonism of the TRPv1 receptor partially corrects muscle metaboreflex overactivity in spontaneously hypertensive rats.

Journal: The Journal of physiology 20111215

Title: Cardiovascular effects of 1-nitro-2-phenylethane, the main constituent of the essential oil of Aniba canelilla, in spontaneously hypertensive rats.

Journal: Fundamental & clinical pharmacology 20111201

Title: An investigation of the safety and pharmacokinetics of the novel TRPV1 antagonist XEN-D0501 in healthy subjects.

Journal: British journal of clinical pharmacology 20111201

Title: TRPV1, TRPA1, and CB1 in the isolated vagus nerve--axonal chemosensitivity and control of neuropeptide release.

Journal: Neuropeptides 20111201

Title: Activation of TRPV1 reduces vascular lipid accumulation and attenuates atherosclerosis.

Journal: Cardiovascular research 20111201

Title: Neurotrophins in the lower urinary tract: becoming of age.

Journal: Current neuropharmacology 20111201

Title: Transient receptor potential vanilloid 1 channels modulate the anxiolytic effect of diazepam.

Journal: Brain research 20111124

Title: The anti-botulism triterpenoid toosendanin elicits calcium increase and exocytosis in rat sensory neurons.

Journal: Cellular and molecular neurobiology 20111101

Title: Suppression of tumor necrosis factor-α-induced nuclear factor κB activation and aromatase activity by capsaicin and its analog capsazepine.

Journal: Journal of medicinal food 20111101

Title: Hydrogen sulfide upregulates cyclooxygenase-2 and prostaglandin E metabolite in sepsis-evoked acute lung injury via transient receptor potential vanilloid type 1 channel activation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20111101

Title: Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain.

Journal: Neuroscience 20111013

Title: Capsaicinoids regulate airway anion transporters through Rho kinase- and cyclic AMP-dependent mechanisms.

Journal: American journal of respiratory cell and molecular biology 20111001

Title: Opposite effect of capsaicin and capsazepine on behavioral thermoregulation in insects.

Journal: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20111001

Title: Contribution of peripheral vanilloid receptor to the nociception induced by injection of spermine in mice.

Journal: Pharmacology, biochemistry, and behavior 20111001

Title: Characterization of capsaicin induced responses in mice vas deferens: evidence of CGRP uptake.

Journal: European journal of pharmacology 20110930

Title: The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis.

Journal: Annals of the rheumatic diseases 20110901

Title: Vanillyl nonanoate protects rat gastric mucosa from ethanol-induced injury through a mechanism involving calcitonin gene-related peptide.

Journal: European journal of pharmacology 20110901

Title: Sensitivity of bronchopulmonary receptors to cold and heat mediated by transient receptor potential cation channel subtypes in an ex vivo rat lung preparation.

Journal: Respiratory physiology & neurobiology 20110815

Title: Cardioprotection by ischemic postconditioning is lost in isolated perfused heart from diabetic rats: Involvement of transient receptor potential vanilloid 1, calcitonin gene-related peptide and substance P.

Journal: Regulatory peptides 20110808

Title: Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1.

Journal: Cardiovascular research 20110801

Title: Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism.

Journal: The Journal of physiology 20110801

Title: TRPV1 agonist piperine but not olvanil enhances glutamatergic spontaneous excitatory transmission in rat spinal substantia gelatinosa neurons.

Journal: Biochemical and biophysical research communications 20110715

Title: Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system.

Journal: Pharmacology & therapeutics 20110701

Title: Desensitization of transient receptor potential ankyrin 1 (TRPA1) by the TRP vanilloid 1-selective cannabinoid arachidonoyl-2 chloroethanolamine.

Journal: Molecular pharmacology 20110701

Title: Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation.

Journal: Pain 20110701

Title: Thermosensitive transient receptor potential channels in human corneal epithelial cells.

Journal: Journal of cellular physiology 20110701

Title: Leukotriene B4 mediates inflammation via TRPV1 in duct obstruction-induced pancreatitis in rats.

Journal: Pancreas 20110701

Title: Characterization of skin inflammation induced by repeated exposure of toluene, xylene, and formaldehyde in mice.

Journal: Environmental toxicology 20110601

Title: TRPM8 in mouse sperm detects temperature changes and may influence the acrosome reaction.

Journal: Journal of cellular physiology 20110601

Title: TRPV1 receptors modulate retinal development.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20110601

Title: The vanilloid capsaicin induces IL-6 secretion in prostate PC-3 cancer cells.

Journal: Cytokine 20110601

Title: The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro.

Journal: Anesthesiology 20110601

Title: Lafutidine, a unique histamine H2-receptor antagonist, inhibits distention-induced gastric acid secretion through an H2 receptor-independent mechanism.

Journal: European journal of pharmacology 20110511

Title: The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110511

Title: Post-ictal analgesia in genetically epilepsy-prone rats is induced by audiogenic seizures and involves cannabinoid receptors in the periaqueductal gray.

Journal: Brain research 20110510

Title: Acteoside inhibits PMA-induced matrix metalloproteinase-9 expression via CaMK/ERK- and JNK/NF-κB-dependent signaling.

Journal: Molecular nutrition & food research 20110501

Title: Disruption of the transient receptor potential vanilloid 1 can affect survival, bacterial clearance, and cytokine gene expression during murine sepsis.

Journal: Anesthesiology 20110501

Title: Characterization of TRPM8-like channels activated by the cooling agent icilin in the macrophage cell line RAW 264.7.

Journal: The Journal of membrane biology 20110501

Title: Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia.

Journal: Nature chemical biology 20110501

Title: TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.

Journal: Nature neuroscience 20110501

Title: The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors.

Journal: The Journal of physiology 20110501

Title: Mechanisms underlying the protective effect of eugenol in rats with acute doxorubicin cardiotoxicity.

Journal: Archives of pharmacal research 20110501

Title: Melittin activates TRPV1 receptors in primary nociceptive sensory neurons via the phospholipase A2 cascade pathways.

Journal: Biochemical and biophysical research communications 20110429

Title: Role of transient receptor potential ankyrin subfamily member 1 in pruritus induced by endothelin-1.

Journal: Neuroscience letters 20110404

Title: Characterization of in vitro metabolism of capsazepine, a vanilloid transient receptor potential channel antagonist, by liquid chromatography quadrupole ion trap mass spectrometry.

Journal: Biomedical chromatography : BMC 20110401

Title: Inhibitory effect of standardized cannabis sativa extract and its ingredient cannabidiol on rat and human bladder contractility.

Journal: Urology 20110401

Title: Increased transient receptor potential vanilloid type 1 (TRPV1) signaling in idiopathic overactive bladder urothelial cells.

Journal: Neurourology and urodynamics 20110401

Title: Human dental pulp fibroblasts express the 'cold-sensing' transient receptor potential channels TRPA1 and TRPM8.

Journal: Journal of endodontics 20110401

Title: Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults.

Journal: Neuroscience 20110331

Title: NOX3 NADPH oxidase couples transient receptor potential vanilloid 1 to signal transducer and activator of transcription 1-mediated inflammation and hearing loss.

Journal: Antioxidants & redox signaling 20110315

Title: Atomic force microscopy of microvillous cell surface dynamics at fixed and living alveolar type II cells.

Journal: Analytical and bioanalytical chemistry 20110301

Title: [Apoptosis inhibition of capsaicin on myocardial ischemia-reperfusion injury in rats].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20110301

Title: Effects of acetazolamide on transient K+ currents and action potentials in nodose ganglion neurons of adult rats.

Journal: CNS neuroscience & therapeutics 20110201

Title: dsRNA-induced expression of thymic stromal lymphopoietin (TSLP) in asthmatic epithelial cells is inhibited by a small airway relaxant.

Journal: Pulmonary pharmacology & therapeutics 20110201

Title: Hesperidin produces antinociceptive response and synergistic interaction with ketorolac in an arthritic gout-type pain in rats.

Journal: Pharmacology, biochemistry, and behavior 20110201

Title: Diabetic rats show reduced cardiac-somatic reflex evoked by intrapericardial capsaicin.

Journal: European journal of pharmacology 20110125

Title: TRPV1 activation is required for hypertonicity-stimulated inflammatory cytokine release in human corneal epithelial cells.

Journal: Investigative ophthalmology & visual science 20110101

Title: Inhibitory effects of zingerone, a pungent component of Zingiber officinale Roscoe, on colonic motility in rats.

Journal: Journal of natural medicines 20110101

Title: TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation.

Journal: Pain 20110101

Title: TRPV channel expression in human skin and possible role in thermally induced cell death.

Journal: Journal of burn care & research : official publication of the American Burn Association 20110101

Title: Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1.

Journal: PloS one 20110101

Title: Antinociception produced by Thalassia testudinum extract BM-21 is mediated by the inhibition of acid sensing ionic channels by the phenolic compound thalassiolin B.

Journal: Molecular pain 20110101

Title: Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components.

Journal: Chinese medicine 20110101

Title: Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation.

Journal: PloS one 20110101

Title: Intestinal epithelial stem/progenitor cells are controlled by mucosal afferent nerves.

Journal: PloS one 20110101

Title: Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice.

Journal: Molecular pain 20110101

Title: Nateglinide stimulates glucagon-like peptide-1 release by human intestinal L cells via a K(ATP) channel-independent mechanism.

Journal: Biological & pharmaceutical bulletin 20110101

Title: The role of cannabinoids in modulating emotional and non-emotional memory processes in the hippocampus.

Journal: Frontiers in behavioral neuroscience 20110101

Title: Differential effects of TRPV1 receptor ligands against nicotine-induced depression-like behaviors.

Journal: BMC pharmacology 20110101

Title: Osmosensitivity of transient receptor potential vanilloid 1 is synergistically enhanced by distinct activating stimuli such as temperature and protons.

Journal: PloS one 20110101

Title: Capsaicin induces reflex scratching in inflamed skin.

Journal: Pharmacology 20110101

Title: Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB(1) receptors.

Journal: Journal of neuroinflammation 20110101

Title: Hydrogen sulfide and neurogenic inflammation in polymicrobial sepsis: involvement of substance P and ERK-NF-κB signaling.

Journal: PloS one 20110101

Title: Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice.

Journal: PloS one 20110101

Title: Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects.

Journal: Frontiers in behavioral neuroscience 20110101

Title: Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism.

Journal: PloS one 20110101

Title: Role of the transient receptor potential vanilloid 1 in inflammation and sepsis.

Journal: Journal of inflammation research 20110101

Title: NF-κB feedback control of JNK1 activation modulates TRPV1-induced increases in IL-6 and IL-8 release by human corneal epithelial cells.

Journal: Molecular vision 20110101

Title: Acute myocardial ischemia enhances the vanilloid TRPV1 and serotonin 5-HT3 receptor-mediated Bezold-Jarisch reflex in rats.

Journal: Pharmacological reports : PR 20110101

Title: Evidence for CGRP re-uptake in rat dura mater encephali.

Journal: British journal of pharmacology 20101201

Title: The proteinase/proteinase-activated receptor-2/transient receptor potential vanilloid-1 cascade impacts pancreatic pain in mice.

Journal: Life sciences 20101120

Title: The protective effect of capsaicin receptor-mediated genistein postconditioning on gastric ischemia-reperfusion injury in rats.

Journal: Digestive diseases and sciences 20101101

Title: Mechanosensitive transient receptor potential vanilloid type 1 channels contribute to vascular remodeling of rat fistula veins.

Journal: Journal of vascular surgery 20101101

Title: Signaling mechanisms involved in the intestinal pro-secretory actions of hydrogen sulfide.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20101101

Title: Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice.

Journal: British journal of anaesthesia 20101101

Title: Phosphorylation of ERK in the spinal dorsal horn following pancreatic pronociceptive stimuli with proteinase-activated receptor-2 agonists and hydrogen sulfide in rats: evidence for involvement of distinct mechanisms.

Journal: Journal of neuroscience research 20101101

Title: Transient receptor potential vanilloid type-1 (TRPV-1) channels contribute to cutaneous thermal hyperaemia in humans.

Journal: The Journal of physiology 20101101

Title: TRPV1 receptors are involved in protein nitration and Müller cell reaction in the acutely axotomized rat retina.

Journal: Experimental eye research 20101101

Title: Calcitonin gene-related peptide inhibits angiotensin II-induced endothelial progenitor cells senescence through up-regulation of klotho expression.

Journal: Atherosclerosis 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Endocannabinoid-dependent LTD in a nociceptive synapse requires activation of a presynaptic TRPV-like receptor.

Journal: Journal of neurophysiology 20101101

Title: Bring on the heat: transient receptor potential vanilloid type-1 (TRPV-1) channels as a sensory link for local thermal hyperaemia.

Journal: The Journal of physiology 20101101

Title: Mechanisms involved in the gastroprotective activity of esculin on acute gastric lesions in mice.

Journal: Chemico-biological interactions 20101006

Title: Ginsenoside Rb1 and paeoniflorin inhibit transient receptor potential vanilloid-1-activated IL-8 and PGE₂ production in a human keratinocyte cell line HaCaT.

Journal: International immunopharmacology 20101001

Title: Modulation of single-channel properties of TRPV1 by phosphorylation.

Journal: The Journal of physiology 20101001

Title: Cardio-respiratory reflexes evoked by phenylbiguanide in rats involve vagal afferents which are not sensitive to capsaicin.

Journal: Acta physiologica (Oxford, England) 20100901

Title: Existence and distinction of acid-evoked currents in rat astrocytes.

Journal: Glia 20100901

Title: Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells.

Journal: Experimental eye research 20100901

Title: Potentiation of the glutamatergic synaptic input to rat locus coeruleus neurons by P2X7 receptors.

Journal: Purinergic signalling 20100901

Title: Cannabinoid receptors as target for treatment of osteoporosis: a tale of two therapies.

Journal: Current neuropharmacology 20100901

Title: Axon reflexes evoked by transient receptor potential vanilloid 1 activation are mediated by tetrodotoxin-resistant voltage-gated Na+ channels in intestinal afferent nerves.

Journal: The Journal of pharmacology and experimental therapeutics 20100801

Title: Role of TRPV1 channels in boar spermatozoa acquisition of fertilizing ability.

Journal: Molecular and cellular endocrinology 20100729

Title: 1-Nitro-2-phenylethane, the main constituent of the essential oil of Aniba canelilla, elicits a vago-vagal bradycardiac and depressor reflex in normotensive rats.

Journal: European journal of pharmacology 20100725

Title: Screening of OATP1B1/3 and OCT1 inhibitors in cryopreserved hepatocytes in suspension.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100711

Title: Activation of phosphatidylinositol-linked D1-like receptors increases spontaneous glutamate release in rat somatosensory cortical neurons in vitro.

Journal: Brain research 20100709

Title: Functional vanilloid receptor-1 in human submandibular glands.

Journal: Journal of dental research 20100701

Title: Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase.

Journal: The Journal of pharmacology and experimental therapeutics 20100701

Title: The role of capsaicin in spontaneous pacemaking activity in gastrointestinal tract.

Journal: Journal of neurogastroenterology and motility 20100701

Title: Capsaicin inhibits the spontaneous pacemaker activity in interstitial cells of cajal from the small intestine of mouse.

Journal: Journal of neurogastroenterology and motility 20100701

Title: 17-Beta-estradiol enhanced allodynia of inflammatory temporomandibular joint through upregulation of hippocampal TRPV1 in ovariectomized rats.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100630

Title: Role of sensory C fibers in hypoxia/reoxygenation-impaired myogenic constriction of cerebral arteries.

Journal: Neurological research 20100601

Title: The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice.

Journal: Pharmacological research 20100601

Title: Effects of TRPV1 activation on synaptic excitation in the dentate gyrus of a mouse model of temporal lobe epilepsy.

Journal: Experimental neurology 20100601

Title: Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.

Journal: The Journal of pharmacology and experimental therapeutics 20100601

Title: Functional roles of TRPV1 channels in lower urinary tract irritated by acetic acid: in vivo evaluations of the sex difference in decerebrate unanesthetized mice.

Journal: American journal of physiology. Renal physiology 20100601

Title: Nitro-oleic acid inhibits firing and activates TRPV1- and TRPA1-mediated inward currents in dorsal root ganglion neurons from adult male rats.

Journal: The Journal of pharmacology and experimental therapeutics 20100601

Title: TRPV channels mediate temperature-sensing in human corneal endothelial cells.

Journal: Experimental eye research 20100601

Title: The nociception induced by glutamate in mice is potentiated by protons released into the solution.

Journal: The journal of pain : official journal of the American Pain Society 20100601

Title: TRPA1 receptor induced relaxation of the human urethra involves TRPV1 and cannabinoid receptor mediated signals, and cyclooxygenase activation.

Journal: The Journal of urology 20100501

Title: Accelerated senescence of endothelial progenitor cells in hypertension is related to the reduction of calcitonin gene-related peptide.

Journal: Journal of hypertension 20100501

Title: In vitro TRPV1 activity of piperine derived amides.

Journal: Bioorganic & medicinal chemistry 20100501

Title: Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions.

Journal: Nature medicine 20100501

Title: Opposing effects of cannabinoids and vanilloids on evoked quantal release at the frog neuromuscular junction.

Journal: Neuroscience letters 20100405

Title: Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Journal: Obesity (Silver Spring, Md.) 20100401

Title: Neuroprotection induced by vitamin E against oxidative stress in hippocampal neurons: involvement of TRPV1 channels.

Journal: Molecular nutrition & food research 20100401

Title: The TRPV1 ion channel antagonist capsazepine inhibits osteoclast and osteoblast differentiation in vitro and ovariectomy induced bone loss in vivo.

Journal: Bone 20100401

Title: Direct activation of transient receptor potential V1 by nickel ions.

Journal: Pflugers Archiv : European journal of physiology 20100401

Title: The TRPv1 receptor is a mediator of the exercise pressor reflex in rats.

Journal: The Journal of physiology 20100401

Title: Pharmacological characterization of cannabinoid receptor activity in the rat-isolated ileum myenteric plexus-longitudinal muscle preparation.

Journal: British journal of pharmacology 20100401

Title: Capsaicin mediates cell death in bladder cancer T24 cells through reactive oxygen species production and mitochondrial depolarization.

Journal: Urology 20100301

Title: Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway.

Journal: Neurochemistry international 20100301

Title: Mechanisms of action of hydrogen sulfide in relaxation of mouse distal colonic smooth muscle.

Journal: European journal of pharmacology 20100225

Title: [The protective mechanism of N-acetylcysteine against ischemia/reperfusion induced gastric injury in rats].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20100225

Title: Behavioral assessment and identification of a molecular marker in a salicylate-induced tinnitus in rats.

Journal: Neuroscience 20100217

Title: Gastroprotective effect of barbatusin and 3-beta-hydroxy-3-deoxibarbatusin, quinonoid diterpenes isolated from Plectranthus grandis, in ethanol-induced gastric lesions in mice.

Journal: Journal of ethnopharmacology 20100217

Title: Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis.

Journal: Critical care medicine 20100201

Title: Pharmacologic antagonism of the oral aversive taste-directed response to capsaicin in a mouse brief access taste aversion assay.

Journal: The Journal of pharmacology and experimental therapeutics 20100201

Title: Glycolic acid induces keratinocyte proliferation in a skin equivalent model via TRPV1 activation.

Journal: Journal of dermatological science 20100201

Title: Influence of capsicum extract and capsaicin on endothelial health.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100201

Title: TRPV1 gene deficiency attenuates miniature EPSC potentiation induced by mannitol and angiotensin II in supraoptic magnocellular neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120

Title: Protective effect of anacardic acids from cashew (Anacardium occidentale) on ethanol-induced gastric damage in mice.

Journal: Chemico-biological interactions 20100105

Title: Amiloride-sensitive channels are a major contributor to mechanotransduction in mammalian muscle spindles.

Journal: The Journal of physiology 20100101

Title: 2-APB and capsazepine-induced Ca2+ influx stimulates clathrin-dependent endocytosis in alveolar epithelial cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Title: Antinociceptive effect of geranylgeraniol and 6alpha,7beta-dihydroxyvouacapan-17beta-oate methyl ester isolated from Pterodon pubescens Benth.

Journal: BMC pharmacology 20100101

Title: Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors.

Journal: PloS one 20100101

Title: Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice.

Journal: Molecular pain 20100101

Title: Effects of topical application of alpha-D-glucosylglycerol on dermal levels of insulin-like growth factor-i in mice and on facial skin elasticity in humans.

Journal: Bioscience, biotechnology, and biochemistry 20100101

Title: 'TRPing' synaptic ribbon function in the rat pineal gland: neuroendocrine regulation involves the capsaicin receptor TRPV1.

Journal: Neuroendocrinology 20100101

Title: Tumor tissue-derived formaldehyde and acidic microenvironment synergistically induce bone cancer pain.

Journal: PloS one 20100101

Title: Emodin down-regulates expression of TRPV1 mRNA and its function in DRG neurons in vitro.

Journal: The American journal of Chinese medicine 20100101

Title: Impact of central and peripheral TRPV1 and ROS levels on proinflammatory mediators and nociceptive behavior.

Journal: Molecular pain 20100101

Title: TRPV1 in brain is involved in acetaminophen-induced antinociception.

Journal: PloS one 20100101

Title: Moving towards supraspinal TRPV1 receptors for chronic pain relief.

Journal: Molecular pain 20100101

Title: The M-channel blocker linopirdine is an agonist of the capsaicin receptor TRPV1.

Journal: Journal of pharmacological sciences 20100101

Title: Involvement of lysophosphatidic acid in bone cancer pain by potentiation of TRPV1 via PKCε pathway in dorsal root ganglion neurons.

Journal: Molecular pain 20100101

Title: Blocking spinal CCR2 with AZ889 reversed hyperalgesia in a model of neuropathic pain.

Journal: Molecular pain 20100101

Title: A non-anesthetized mouse model for recording sensory urinary bladder activity.

Journal: Frontiers in neurology 20100101

Title: Effect of resiniferatoxin on glutamatergic spontaneous excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord.

Journal: Neuroscience 20091229

Title: Characterization of an AM404 analogue, N-(3-hydroxyphenyl)arachidonoylamide, as a substrate and inactivator of prostaglandin endoperoxide synthase.

Journal: Biochemistry 20091229

Title: Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium.

Journal: Toxicology 20091221

Title: Sex differences in the expression profile of acid-sensing ion channels in the mouse urinary bladder: a possible involvement in irritative bladder symptoms.

Journal: BJU international 20091201

Title: Anionic linear aliphatic surfactants activate TRPV1: a possible endpoint for estimation of detergent induced eye nociception?

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20091201

Title: Release of ATP from rat urinary bladder mucosa: role of acid, vanilloids and stretch.

Journal: British journal of pharmacology 20091201

Title: The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells.

Journal: Journal of immunotoxicology 20091201

Title: Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle.

Journal: Journal of the peripheral nervous system : JPNS 20091201

Title: Characterization of a calcitonin gene-related peptide release assay in rat isolated distal colon.

Journal: Archives of pharmacal research 20091201

Title: Importance of the non-selective cation channel TRPV1 for microglial reactive oxygen species generation.

Journal: Journal of neuroimmunology 20091130

Title: Evodiamine inhibits adipogenesis via the EGFR-PKCalpha-ERK signaling pathway.

Journal: FEBS letters 20091119

Title: Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20091113

Title: Non-selective cation channel activity is required for lysophosphatidylcholine-induced monocyte migration.

Journal: Journal of cellular physiology 20091101

Title: Capsaicin protects mouse neuromuscular junctions from the neuroparalytic effects of botulinum neurotoxin a.

Journal: The Journal of pharmacology and experimental therapeutics 20091101

Title: Endogenous expression of TRPV1 channel in cultured human melanocytes.

Journal: Journal of dermatological science 20091101

Title: Do distinct populations of dorsal root ganglion neurons account for the sensory peptidergic innervation of the kidney?

Journal: American journal of physiology. Renal physiology 20091101

Title: Electrophysiological and morphological properties of neurons in the substantia gelatinosa of the mouse trigeminal subnucleus caudalis.

Journal: Pain 20091101

Title: Acid-evoked Ca2+ signalling in rat sensory neurones: effects of anoxia and aglycaemia.

Journal: Pflugers Archiv : European journal of physiology 20091101

Title: Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents.

Journal: British journal of pharmacology 20091101

Title: Evidence of TRPV1 receptor and PKC signaling pathway in the antinociceptive effect of amyrin octanoate.

Journal: Brain research 20091027

Title: Mediating roles of the vanilloid receptor TRPV1 in activation of rat primary afferent nociceptive neurons by formaldehyde.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20091025

Title: Essential role for TRPV1 in stress-induced (mast cell-dependent) colonic hypersensitivity in maternally separated rats.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20091001

Title: Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability.

Journal: Endocrinology 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Capsaicin affects brain function in a model of hepatic encephalopathy associated with fulminant hepatic failure in mice.

Journal: British journal of pharmacology 20091001

Title: Proton acts as a neurotransmitter for nicotine-induced adrenergic and calcitonin gene-related peptide-containing nerve-mediated vasodilation in the rat mesenteric artery.

Journal: The Journal of pharmacology and experimental therapeutics 20090901

Title: Hydrogen sulfide prevents ethanol-induced gastric damage in mice: role of ATP-sensitive potassium channels and capsaicin-sensitive primary afferent neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20090901

Title: Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain.

Journal: The Journal of pharmacology and experimental therapeutics 20090901

Title: AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats.

Journal: Translational research : the journal of laboratory and clinical medicine 20090901

Title: Possible role for TRPV1 in neomycin-induced inhibition of visceral hypersensitivity in rat.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090801

Title: Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats.

Journal: Psychopharmacology 20090801

Title: Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia.

Journal: Pain 20090801

Title: Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner.

Journal: Carcinogenesis 20090801

Title: N-arachidonyl dopamine sensitizes rat capsaicin-sensitive lung vagal afferents via activation of TRPV1 receptors.

Journal: Respiratory physiology & neurobiology 20090731

Title: Involvement of increased expression of transient receptor potential melastatin 8 in oxaliplatin-induced cold allodynia in mice.

Journal: Neuroscience letters 20090717

Title: Mechanotransduction and chemosensitivity of two major classes of bladder afferents with endings in the vicinity to the urothelium.

Journal: The Journal of physiology 20090715

Title: Role of ET(A) and ET(B) endothelin receptors on endothelin-1-induced potentiation of nociceptive and thermal hyperalgesic responses evoked by capsaicin in rats.

Journal: Neuroscience letters 20090703

Title: (Endo)cannabinoids mediate different Ca2+ entry mechanisms in human bronchial epithelial cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20090701

Title: QX-314 produces long-lasting local anesthesia modulated by transient receptor potential vanilloid receptors in mice.

Journal: Anesthesiology 20090701

Title: Exposure to concentrated coarse air pollution particles causes mild cardiopulmonary effects in healthy young adults.

Journal: Environmental health perspectives 20090701

Title: Ethanol aggravates itch-related scratching in hairless mice developing atopic dermatitis.

Journal: European journal of pharmacology 20090602

Title: A novel role for the TRPV1 channel in UV-induced matrix metalloproteinase (MMP)-1 expression in HaCaT cells.

Journal: Journal of cellular physiology 20090601

Title: Bronchoconstriction induced by hyperventilation with humidified hot air: role of TRPV1-expressing airway afferents.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20090601

Title: Depolarization-induced release of endocannabinoids by murine dorsal motor nucleus of the vagus nerve neurons differentially regulates inhibitory and excitatory neurotransmission.

Journal: Neuropharmacology 20090601

Title: Transient receptor potential melastatin 8 channel involvement in the regulation of vascular tone.

Journal: American journal of physiology. Heart and circulatory physiology 20090601

Title: Enhancement of the hypotensive effects of intrathecally injected endocannabinoids by the entourage compound palmitoylethanolamide.

Journal: European journal of pharmacology 20090521

Title: A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090513

Title: Transient receptor potential vanilloid type 1 receptor regulates glutamatergic synaptic inputs to the spinothalamic tract neurons of the spinal cord deep dorsal horn.

Journal: Neuroscience 20090505

Title: Excitation of cutaneous C nociceptors by intraplantar administration of anandamide.

Journal: Brain research 20090501

Title: Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats.

Journal: Psychopharmacology 20090401

Title: Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20090401

Title: Functional TRP and ASIC-like channels in cultured urothelial cells from the rat.

Journal: American journal of physiology. Renal physiology 20090401

Title: Mechanisms involved in oleamide-induced vasorelaxation in rat mesenteric resistance arteries.

Journal: European journal of pharmacology 20090401

Title: Functional type I vanilloid receptor expression by substantia gelatinosa neurons of trigeminal subnucleus caudalis in mice.

Journal: Neuroscience letters 20090320

Title: Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus.

Journal: European journal of pharmacology 20090315

Title: Modulation of anxiety-like behaviour by Transient Receptor Potential Vanilloid Type 1 (TRPV1) channels located in the dorsolateral periaqueductal gray.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090301

Title: N-acyldopamines control striatal input terminals via novel ligand-gated cation channels.

Journal: Neuropharmacology 20090301

Title: Functional characterization of nonadrenergic noncholinergic neurotransmitter release via endocannabinoids: an in vitro study in rabbit corpus cavernosum.

Journal: The journal of sexual medicine 20090301

Title: Deletion of vanilloid receptor (TRPV1) in mice alters behavioral effects of ethanol.

Journal: Neuropharmacology 20090301

Title: Nociceptive vascular reflexes evoked by scorpion venom modulate cardiorespiratory parameters involving vanilloid receptor 1 in anaesthetised rats.

Journal: Neuroscience letters 20090227

Title: TRPA1 activation by lidocaine in nerve terminals results in glutamate release increase.

Journal: Biochemical and biophysical research communications 20090220

Title: Excitatory and inhibitory urinary bladder reflexes induced by stimulation of cervicovaginal capsaicin-sensitive sensory fibers in rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20090201

Title: Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat.

Journal: Gut 20090201

Title: Salt intake augments hypotensive effects of transient receptor potential vanilloid 4: functional significance and implication.

Journal: Hypertension (Dallas, Tex. : 1979) 20090201

Title: Activation of sensory neurons reduces ischemia/reperfusion-induced acute renal injury in rats.

Journal: Anesthesiology 20090201

Title: Capsaicin-induced glutamate release is implicated in nociceptive processing through activation of ionotropic glutamate receptors and group I metabotropic glutamate receptor in primary afferent fibers.

Journal: Journal of pharmacological sciences 20090201

Title: Interaction with phosphoinositides confers adaptation onto the TRPV1 pain receptor.

Journal: PLoS biology 20090201

Title: Differential effects of topically applied formalin and aromatic compounds on neurogenic-mediated microvascular leakage in rat skin.

Journal: Toxicology 20090108

Title: Capsaicin, a component of red peppers, induces expression of androgen receptor via PI3K and MAPK pathways in prostate LNCaP cells.

Journal: FEBS letters 20090105

Title: TRPV1 channels facilitate glutamate transmission in the striatum.

Journal: Molecular and cellular neurosciences 20090101

Title: Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats.

Journal: The Journal of pharmacology and experimental therapeutics 20090101

Title: Contribution of transient receptor potential vanilloid subtype 1 to the analgesic and antihyperalgesic activity of nefopam in rodents.

Journal: Pharmacology 20090101

Title: Antiaversive effects of cannabinoids: is the periaqueductal gray involved?

Journal: Neural plasticity 20090101

Title: Vanilloid receptor antagonists: emerging class of novel anti-inflammatory agents for pain management.

Journal: Current pharmaceutical design 20090101

Title: Reactive oxygen species mediate TNFR1 increase after TRPV1 activation in mouse DRG neurons.

Journal: Molecular pain 20090101

Title: TRPM8, a versatile channel in human sperm.

Journal: PloS one 20090101

Title: Tumor necrosis factor-alpha (TNF-alpha) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes.

Journal: Molecular pain 20090101

Title: Selective targeting of TRPV1 expressing sensory nerve terminals in the spinal cord for long lasting analgesia.

Journal: PloS one 20090101

Title: NMDA receptor subunit expression and PAR2 receptor activation in colospinal afferent neurons (CANs) during inflammation induced visceral hypersensitivity.

Journal: Molecular pain 20090101

Title: Dynamic regulation of the endocannabinoid system: implications for analgesia.

Journal: Molecular pain 20090101

Title: Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels.

Journal: Molecular pain 20090101

Title: Polymorphisms in gene encoding TRPV1-receptor involved in pain perception are unrelated to chronic pancreatitis.

Journal: BMC gastroenterology 20090101

Title: [Modulation of the smooth muscle contractions of the rat vas deferens by TRPM8 channel agonist menthol].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101

Title: TRPV1 stimulation triggers apoptotic cell death of rat cortical neurons.

Journal: Biochemical and biophysical research communications 20081226

Title: Short interfering RNA against transient receptor potential vanilloid 1 attenuates cisplatin-induced hearing loss in the rat.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081203

Title: CO2 chemosensing in rat oesophagus.

Journal: Gut 20081201

Title: Facilitation of contextual fear memory extinction and anti-anxiogenic effects of AM404 and cannabidiol in conditioned rats.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20081201

Title: Virodhamine relaxes the human pulmonary artery through the endothelial cannabinoid receptor and indirectly through a COX product.

Journal: British journal of pharmacology 20081201

Title: Phosphorylation of TRPV1 by neurokinin-1 receptor agonist exaggerates the capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons.

Journal: Neuropharmacology 20081201

Title: Rutaecarpine inhibits hypoxia/reoxygenation-induced apoptosis in rat hippocampal neurons.

Journal: Neuropharmacology 20081201

Title: Cannabinoids and capsaicin improve liver function following thioacetamide-induced acute injury in mice.

Journal: The American journal of gastroenterology 20081201

Title: Extracellular signal-regulated kinases mediate melittin-induced hypersensitivity of spinal neurons to chemical and thermal but not mechanical stimuli.

Journal: Brain research bulletin 20081125

Title: TRPV1 mediates the uterine capsaicin-induced NMDA NR2B-dependent cross-organ reflex sensitization in anesthetized rats.

Journal: American journal of physiology. Renal physiology 20081101

Title: Characterization of A-425619 at native TRPV1 receptors: a comparison between dorsal root ganglia and trigeminal ganglia.

Journal: European journal of pharmacology 20081031

Title: Transient receptor potential vanilloid 1-mediated expression and secretion of endothelial cell-derived calcitonin gene-related peptide.

Journal: Regulatory peptides 20081009

Title: Dependence of regulatory volume decrease on transient receptor potential vanilloid 4 (TRPV4) expression in human corneal epithelial cells.

Journal: Cell calcium 20081001

Title: Heat-induced MMP-1 expression is mediated by TRPV1 through PKCalpha signaling in HaCaT cells.

Journal: Experimental dermatology 20081001

Title: Behavioral and electrophysiological evidence for the differential functions of TRPV1 at early and late stages of chronic inflammatory nociception in rats.

Journal: Neurochemical research 20081001

Title: Calcitonin gene-related peptide-mediated antihypertensive and anti-platelet effects by rutaecarpine in spontaneously hypertensive rats.

Journal: Peptides 20081001

Title: Transient receptor potential vanilloid subtype 1 channel mediated neuropeptide secretion and depressor effects: role of endoplasmic reticulum associated Ca2+ release receptors in rat dorsal root ganglion neurons.

Journal: Journal of hypertension 20081001

Title: A TRPV channel modulates C. elegans neurosecretion, larval starvation survival, and adult lifespan.

Journal: PLoS genetics 20081001

Title: Capsaicin inhibits the in vitro binding of peptides selective for mu- and kappa-opioid, and nociceptin-receptors.

Journal: Brain research bulletin 20080930

Title: Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1.

Journal: Journal of neurophysiology 20080901

Title: Estrous cycle variation of TRPV1-mediated cross-organ sensitization between uterus and NMDA-dependent pelvic-urethra reflex activity.

Journal: American journal of physiology. Endocrinology and metabolism 20080901

Title: Elevated temperatures alter TRPV1 agonist-evoked excitability of dorsal root ganglion neurons.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080901

Title: Antistress effect of TRPV1 channel on synaptic plasticity and spatial memory.

Journal: Biological psychiatry 20080815

Title: A subpopulation of capsaicin-sensitive porcine dorsal root ganglion neurons is lacking hyperpolarization-activated cyclic nucleotide-gated channels.

Journal: European journal of pain (London, England) 20080801

Title: Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans.

Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20080801

Title: Role of TRPV1 channels in renal haemodynamics and function in Dahl salt-sensitive hypertensive rats.

Journal: Experimental physiology 20080801

Title: Involvement of TRPV1 in nociceptive behavior in a rat model of cancer pain.

Journal: The journal of pain : official journal of the American Pain Society 20080801

Title: Dual effect of anandamide on rat placenta nitric oxide synthesis.

Journal: Placenta 20080801

Title: SA13353 (1-[2-(1-Adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea) inhibits TNF-alpha production through the activation of capsaicin-sensitive afferent neurons mediated via transient receptor potential vanilloid 1 in vivo.

Journal: European journal of pharmacology 20080707

Title: Sustained increase of Ca+2 oscillations after chronic TRPV1 receptor activation with capsaicin in cultured spinal neurons.

Journal: Brain research 20080707

Title: Therapeutic potential of 1-methylnicotinamide against acute gastric lesions induced by stress: role of endogenous prostacyclin and sensory nerves.

Journal: The Journal of pharmacology and experimental therapeutics 20080701

Title: In vivo pharmacological evaluation of compound 48/80-induced airways oedema by MRI.

Journal: British journal of pharmacology 20080701

Title: Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.

Journal: The Journal of clinical investigation 20080701

Title: Gastroprotective mechanisms of centipedic acid, a natural diterpene from Egletes viscosa LESS.

Journal: Biological & pharmaceutical bulletin 20080701

Title: Attenuation of anxiety-related behaviour after the antagonism of transient receptor potential vanilloid type 1 channels in the rat ventral hippocampus.

Journal: Behavioural pharmacology 20080701

Title: [Protective effect of capsaicin on against myocardial ischemia-reperfusion injury of rat in vivo].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20080701

Title: Gastroprotective action of orexin-A against stress-induced gastric damage is mediated by endogenous prostaglandins, sensory afferent neuropeptides and nitric oxide.

Journal: Regulatory peptides 20080605

Title: The activation of transient receptor potential vanilloid receptor subtype 1 by capsaicin without extracellular Ca2+ is involved in the mechanism of distinct substance P release in cultured rat dorsal root ganglion neurons.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080601

Title: Interdependent regulation of afferent renal nerve activity and renal function: role of transient receptor potential vanilloid type 1, neurokinin 1, and calcitonin gene-related peptide receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20080601

Title: Impaired capsaicin-induced relaxation of coronary arteries in a porcine model of the metabolic syndrome.

Journal: American journal of physiology. Heart and circulatory physiology 20080601

Title: Monoacylglycerols activate capsaicin receptor, TRPV1.

Journal: Lipids 20080601

Title: The analgesic drug, tramadol, acts as an agonist of the transient receptor potential vanilloid-1.

Journal: Anesthesia and analgesia 20080601

Title: Inflammation reduces mechanical thresholds in a population of transient receptor potential channel A1-expressing nociceptors in the rat.

Journal: The European journal of neuroscience 20080601

Title: Functional expression of transient receptor potential vanilloid-related channels in chronically hypoxic human pulmonary arterial smooth muscle cells.

Journal: The Journal of membrane biology 20080601

Title: TRPV1: a target for next generation analgesics.

Journal: Current neuropharmacology 20080601

Title: TRPV1 mediates cell death in rat synovial fibroblasts through calcium entry-dependent ROS production and mitochondrial depolarization.

Journal: Biochemical and biophysical research communications 20080516

Title: Quebrachitol-induced gastroprotection against acute gastric lesions: role of prostaglandins, nitric oxide and K+ ATP channels.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080501

Title: The TRPV1 receptor is associated with preferential stress in large dorsal root ganglion neurons in early diabetic sensory neuropathy.

Journal: Journal of neurochemistry 20080501

Title: Functional study on TRPV1-mediated signalling in the mouse small intestine: involvement of tachykinin receptors.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080501

Title: TRPV1-mediated protection against endotoxin-induced hypotension and mortality in rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080501

Title: Segmental regulation of sodium and water excretion by TRPV1 activation in the kidney.

Journal: Journal of cardiovascular pharmacology 20080501

Title: A saturated N-acylethanolamine other than N-palmitoyl ethanolamine with anti-inflammatory properties: a neglected story..

Journal: Journal of neuroendocrinology 20080501

Title: Novel gating and sensitizing mechanism of capsaicin receptor (TRPV1): tonic inhibitory regulation of extracellular sodium through the external protonation sites on TRPV1.

Journal: The Journal of biological chemistry 20080404

Title: Cardiac oxidative stress and electrophysiological changes in rats exposed to concentrated ambient particles are mediated by TRP-dependent pulmonary reflexes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080401

Title: Pronociceptive response elicited by TRPA1 receptor activation in mice.

Journal: Neuroscience 20080318

Title: SAR studies of capsazepinoid bronchodilators. Part 2: Chlorination and catechol replacement in the A-ring.

Journal: Bioorganic & medicinal chemistry 20080301

Title: SAR studies of capsazepinoid bronchodilators. Part 1: The importance of the catechol moiety and aspects of the B-ring structure.

Journal: Bioorganic & medicinal chemistry 20080301

Title: Effect of increasing temperature on TRPV1-mediated responses in isolated rat pulmonary sensory neurons.

Journal: American journal of physiology. Lung cellular and molecular physiology 20080301

Title: SAR studies of capsazepinoid bronchodilators 3: The thiourea part (coupling region) and the 2-(4-chlorophenyl)ethyl moiety (C-region).

Journal: Bioorganic & medicinal chemistry 20080301

Title: Gastroprotective effect of a flavone from Lonchocarpus araripensis Benth. (Leguminosae) and the possible mechanism.

Journal: The Journal of pharmacy and pharmacology 20080301

Title: Increased GFR and renal excretory function by activation of TRPV1 in the isolated perfused kidney.

Journal: Pharmacological research 20080301

Title: Lafutidine facilitates calcitonin gene-related peptide (CGRP) nerve-mediated vasodilation via vanilloid-1 receptors in rat mesenteric resistance arteries.

Journal: Journal of pharmacological sciences 20080301

Title: ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1.

Journal: Current neuropharmacology 20080301

Title: Herbal compounds and toxins modulating TRP channels.

Journal: Current neuropharmacology 20080301

Title: The role of TRPV1 receptors in the antinociceptive effect of anandamide at spinal level.

Journal: Pain 20080201

Title: Effect of capsaicin on plasma and tissue levels of insulin-like growth factor-I in spontaneously hypertensive rats.

Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20080201

Title: Transient receptor potential vanilloid type 1 channels act as mechanoreceptors and cause substance P release and sensory activation in rat kidneys.

Journal: American journal of physiology. Renal physiology 20080201

Title: The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons.

Journal: The Journal of clinical investigation 20080201

Title: Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis.

Journal: PLoS biology 20080201

Title: Involvement of serotonin receptors 5-HT1 and 5-HT2 in 12(S)-HPETE-induced scratching in mice.

Journal: European journal of pharmacology 20080128

Title: Transient receptor potential vanilloid 1 (TRPV1) channels in cultured rat Sertoli cells regulate an acid sensing chloride channel.

Journal: Biochemical pharmacology 20080115

Title: Stereospecific high-affinity TRPV1 antagonists: chiral N-(2-benzyl-3-pivaloyloxypropyl) 2-[4-(methylsulfonylamino)phenyl]propionamide analogues.

Journal: Journal of medicinal chemistry 20080110

Title: Inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1.

Journal: Journal of the National Cancer Institute 20080102

Title: Discovery of a potent and long-acting bronchorelaxing capsazepinoid, RESPIR 4-95.

Journal: Pulmonary pharmacology & therapeutics 20080101

Title: Control of excitatory synaptic transmission by capsaicin is unaltered in TRPV1 vanilloid receptor knockout mice.

Journal: Neurochemistry international 20080101

Title: Ethanol causes neurogenic vasodilation by TRPV1 activation and CGRP release in the trigeminovascular system of the guinea pig.

Journal: Cephalalgia : an international journal of headache 20080101

Title: TRPV1 receptor signaling mediates afferent nerve sensitization during colitis-induced motility disorders in rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080101

Title: Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia.

Journal: Molecular pain 20080101

Title: Molecular and cellular limits to somatosensory specificity.

Journal: Molecular pain 20080101

Title: PPARgamma and Apoptosis in Cancer.

Journal: PPAR research 20080101

Title: Histamine-induced itch and its relationship with pain.

Journal: Molecular pain 20080101

Title: Direct activation of transient receptor potential vanilloid 1(TRPV1) by diacylglycerol (DAG).

Journal: Molecular pain 20080101

Title: Differential stimulatory effects of cannabinoids on VIP release and NO synthase activity in synaptosomal fractions from rat ileum.

Journal: Neuropeptides 20080101

Title: Human keratinocytes are vanilloid resistant.

Journal: PloS one 20080101

Title: Mechanisms involved in an increment of multimodal excitability of medullary and upper cervical dorsal horn neurons following cutaneous capsaicin treatment.

Journal: Molecular pain 20080101

Title: TRPM8 mechanism of cold allodynia after chronic nerve injury.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20071212

Title: Transient receptor potential vanilloid 1 activation induces inflammatory cytokine release in corneal epithelium through MAPK signaling.

Journal: Journal of cellular physiology 20071201

Title: Anandamide improves the impaired nitric oxide-mediated neurogenic relaxation of the corpus cavernosum in diabetic rats: involvement of cannabinoid CB1 and vanilloid VR1 receptors.

Journal: BJU international 20071201

Title: Neuroprotective effects of glyceryl nonivamide against microglia-like cells and 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y human dopaminergic neuroblastoma cells.

Journal: The Journal of pharmacology and experimental therapeutics 20071201

Title: Voltage is a partial activator of rat thermosensitive TRP channels.

Journal: The Journal of physiology 20071201

Title: Delta9-tetrahydrocannabinol (THC) and AM 404 protect against cerebral ischaemia in gerbils through a mechanism involving cannabinoid and opioid receptors.

Journal: British journal of pharmacology 20071201

Title: Increased depressor response to N-arachidonoyl-dopamine during high salt intake: role of the TRPV1 receptor.

Journal: Journal of hypertension 20071201

Title: Cannabinoids in health and disease.

Journal: Dialogues in clinical neuroscience 20071201

Title: Involvement of peripheral TRPV1 in TMJ hyperalgesia induced by ethanol withdrawal.

Journal: Life sciences 20071130

Title: Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.

Journal: British journal of pharmacology 20071101

Title: Involvement of a capsaicin-sensitive TRPV1-independent mechanism in lipopolysaccharide-induced fever in chickens.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20071101

Title: Delta 9-tetrahydrocannabinol inhibits electrically-evoked CGRP release and capsaicin-sensitive sensory neurogenic vasodilatation in the rat mesenteric arterial bed.

Journal: British journal of pharmacology 20071101

Title: Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors.

Journal: Experimental neurology 20071101

Title: Transient receptor potential vanilloid-1 mediates heat-shock-induced matrix metalloproteinase-1 expression in human epidermal keratinocytes.

Journal: The Journal of investigative dermatology 20071001

Title: Capsaicin-induced avoidance behavior in the terrestrial Gastropoda Megalobulimus abbreviatus: evidence for TRPV-1 signaling and opioid modulation in response to chemical noxious stimuli.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20071001

Title: Fatty acyl amides of endogenous tetrahydroisoquinolines are active at the recombinant human TRPV1 receptor.

Journal: Bioorganic & medicinal chemistry 20070915

Title: Acid-induced modulation of airway basal tone and contractility: role of acid-sensing ion channels (ASICs) and TRPV1 receptor.

Journal: Life sciences 20070908

Title: 12-Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070901

Title: Surfactant-induced TRPV1 activity--a novel mechanism for eye irritation?

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070901

Title: TRPV1 gene knockout impairs preconditioning protection against myocardial injury in isolated perfused hearts in mice.

Journal: American journal of physiology. Heart and circulatory physiology 20070901

Title: Bladder afferent sensitivity in wild-type and TRPV1 knockout mice.

Journal: The Journal of physiology 20070901

Title: Eugenol inhibits K+ currents in trigeminal ganglion neurons.

Journal: Journal of dental research 20070901

Title: Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons.

Journal: The European journal of neuroscience 20070901

Title: A pharmacological study of slowly adapting mechanoreceptors responsive to cold thermal stimulation.

Journal: Neuroscience 20070824

Title: 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20070814

Title: Role of capsaicin-sensitive sensory nerves in protease-activated receptor-2-mediated contraction of rat urinary bladder.

Journal: European journal of pharmacology 20070813

Title: Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with osteoarthritis and rheumatoid arthritis.

Journal: Biochemical and biophysical research communications 20070810

Title: Capsaicin-induced apoptosis of glioma cells is mediated by TRPV1 vanilloid receptor and requires p38 MAPK activation.

Journal: Journal of neurochemistry 20070801

Title: Activation of recombinant human TRPV1 receptors expressed in SH-SY5Y human neuroblastoma cells increases [Ca(2+)](i), initiates neurotransmitter release and promotes delayed cell death.

Journal: Journal of neurochemistry 20070801

Title: Bradykinin-induced nuclear factor of activated T-cells-dependent transcription in rat dorsal root ganglion neurons.

Journal: Molecular pharmacology 20070801

Title: Atrial natriuretic peptide reduces ischemia/reperfusion-induced spinal cord injury in rats by enhancing sensory neuron activation.

Journal: The Journal of pharmacology and experimental therapeutics 20070801

Title: Effects of anandamide and noxious heat on intracellular calcium concentration in nociceptive drg neurons of rats.

Journal: Journal of neurophysiology 20070801

Title: A potential role for the vanilloid receptor TRPV1 in the therapeutic effect of curcumin in dinitrobenzene sulphonic acid-induced colitis in mice.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070801

Title: Cannabidiol reduced the striatal atrophy caused 3-nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1 and adenosine A2A receptors.

Journal: The European journal of neuroscience 20070801

Title: A novel function of capsaicin-sensitive TRPV1 channels: involvement in cell migration.

Journal: Cell calcium 20070701

Title: The synthetic cannabinoids attenuate allodynia and hyperalgesia in a rat model of trigeminal neuropathic pain.

Journal: Neuropharmacology 20070701

Title: Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats.

Journal: Investigative ophthalmology & visual science 20070701

Title: Preserving cardiac output with beta-adrenergic receptor blockade and inhibiting the Bezold-Jarisch reflex during resuscitation from hemorrhage.

Journal: The Journal of trauma 20070701

Title: The anandamide transport inhibitor AM404 reduces ethanol self-administration.

Journal: The European journal of neuroscience 20070701

Title: AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain.

Journal: Brain research 20070604

Title: Transient receptor potential vanilloid 1 antagonist, capsazepine, improves survival in a rat hemorrhagic shock model.

Journal: Annals of surgery 20070601

Title: The potential of transient receptor potential vanilloid type 1 channel modulators for the treatment of pain.

Journal: Journal of medicinal chemistry 20070531

Title: Novel agonistic action of mustard oil on recombinant and endogenous porcine transient receptor potential V1 (pTRPV1) channels.

Journal: Biochemical pharmacology 20070515

Title: Mouse colon sensory neurons detect extracellular acidosis via TRPV1.

Journal: American journal of physiology. Cell physiology 20070501

Title: Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet.

Journal: The Journal of pharmacology and experimental therapeutics 20070501

Title: Antinociceptive pharmacology of N-(4-chlorobenzyl)-N'-(4-hydroxy-3-iodo-5-methoxybenzyl) thiourea, a high-affinity competitive antagonist of the transient receptor potential vanilloid 1 receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20070501

Title: Cannabinoid and vanilloid effects of R(+)-methanandamide in the hemisected meningeal preparation.

Journal: Cephalalgia : an international journal of headache 20070501

Title: Activation of TRPA1 channel facilitates excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070418

Title: Capsicum ethanol extracts and capsaicin enhance interleukin-2 and interferon-gamma production in cultured murine Peyer's patch cells ex vivo.

Journal: Life sciences 20070403

Title: Capsaicin induces the production of IL-6 in human upper respiratory epithelial cells.

Journal: Life sciences 20070403

Title: Involvement of endothelial cell-derived CGRP in heat stress-induced protection of endothelial function.

Journal: Vascular pharmacology 20070401

Title: The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport.

Journal: The Journal of pharmacology and experimental therapeutics 20070401

Title: Heat sensitization in skin and muscle nociceptors expressing distinct combinations of TRPV1 and TRPV2 protein.

Journal: Journal of neurophysiology 20070401

Title: Capsaicin-induced mucus secretion in rat airways assessed in vivo and non-invasively by magnetic resonance imaging.

Journal: British journal of pharmacology 20070401

Title: The preventive effect of Daikenchuto on postoperative adhesion-induced intestinal obstruction in rats.

Journal: Inflammopharmacology 20070401

Title: Pharmacological characterization of receptor types mediating the dilator action of anandamide on blood vessels of the rat knee joint.

Journal: Life sciences 20070327

Title: Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death.

Journal: Biochemical and biophysical research communications 20070302

Title: Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors.

Journal: British journal of pharmacology 20070301

Title: Pharmacological characterisation of capsaicin-induced relaxations in human and porcine isolated arteries.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20070301

Title: TRPV1 mediates histamine-induced itching via the activation of phospholipase A2 and 12-lipoxygenase.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070227

Title: The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain.

Journal: European journal of pharmacology 20070205

Title: Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats.

Journal: Digestive diseases and sciences 20070201

Title: Vanilloid (subtype 1) receptor-modulatory drugs inhibit [3H]batrachotoxinin-A 20-alpha-benzoate binding to Na+ channels.

Journal: Basic & clinical pharmacology & toxicology 20070201

Title: TRPV1 is a novel target for omega-3 polyunsaturated fatty acids.

Journal: The Journal of physiology 20070115

Title: Effects of capsazepine on human small airway responsiveness unravel a novel class of bronchorelaxants.

Journal: Pulmonary pharmacology & therapeutics 20070101

Title: Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: Halogenation of 4-hydroxy-3-methoxybenzyl thiourea TRPV1 agonists showed enhanced antagonism to capsaicin.

Journal: Bioorganic & medicinal chemistry letters 20070101

Title: Danaparoid sodium reduces ischemia/reperfusion-induced liver injury in rats by attenuating inflammatory responses.

Journal: Thrombosis and haemostasis 20070101

Title: Animal models of cough: literature review and presentation of a novel cigarette smoke-enhanced cough model in the guinea-pig.

Journal: Pulmonary pharmacology & therapeutics 20070101

Title: TRPV1 is involved in stretch-evoked contractile changes in the rat autonomous bladder model: a study with piperine, a new TRPV1 agonist.

Journal: Neurourology and urodynamics 20070101

Title: Transient receptor potential ion channels control thermoregulatory behaviour in reptiles.

Journal: PloS one 20070101

Title: Anti-calmodulins and tricyclic adjuvants in pain therapy block the TRPV1 channel.

Journal: PloS one 20070101

Title: TRPV1-mediated diuresis and natriuresis induced by hypertonic saline perfusion of the renal pelvis.

Journal: American journal of nephrology 20070101

Title: Novel technique for estimating cerebrovascular permeability demonstrates capsazepine protection following ischemia-reperfusion.

Journal: Microcirculation (New York, N.Y. : 1994) 20070101

Title: Roles of TRPV1 and neuropeptidergic receptors in dorsal root reflex-mediated neurogenic inflammation induced by intradermal injection of capsaicin.

Journal: Molecular pain 20070101

Title: Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists.

Journal: Molecular pain 20070101

Title: Inhibition of citric acid- and capsaicin-induced cough by novel TRPV-1 antagonist, V112220, in guinea-pig.

Journal: Cough (London, England) 20070101

Title: Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB(1) and VR(1) receptors.

Journal: British journal of pharmacology 20061201

Title: Impaired vasodilation in response to perivascular nerve stimulation in mesenteric arteries of TRPV1-null mutant mice.

Journal: Journal of hypertension 20061201

Title: Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides?

Journal: European journal of pharmacology 20061121

Title: Role of substance P in hydrogen sulfide-induced pulmonary inflammation in mice.

Journal: American journal of physiology. Lung cellular and molecular physiology 20061101

Title: TRPV1 receptors and nasal trigeminal chemesthesis.

Journal: Chemical senses 20061101

Title: Capsaicin inhibits catecholamine secretion and synthesis by blocking Na+ and Ca2+ influx through a vanilloid receptor-independent pathway in bovine adrenal medullary cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20061101

Title: Differential mechanisms mediating depressor and diuretic effects of anandamide.

Journal: Journal of hypertension 20061101

Title: Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon.

Journal: Gastroenterology 20061101

Title: Characterization of the vasorelaxation to methanandamide in rat gastric arteries.

Journal: Canadian journal of physiology and pharmacology 20061101

Title: Transient receptor potential vanilloid subtype 1 mediates microglial cell death in vivo and in vitro via Ca2+-mediated mitochondrial damage and cytochrome c release.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20061001

Title: Eugenol inhibits sodium currents in dental afferent neurons.

Journal: Journal of dental research 20061001

Title: Thermal sensitivity of isolated vagal pulmonary sensory neurons: role of transient receptor potential vanilloid receptors.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060901

Title: A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats.

Journal: Neuropharmacology 20060901

Title: Effect of anandamide on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum.

Journal: European journal of pharmacology 20060821

Title: Effect of capsazepine on cytosolic Ca(2+) levels and proliferation of human prostate cancer cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060801

Title: Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20060801

Title: Mediator mechanisms involved in TRPV1 and P2X receptor-mediated, ROS-evoked bradypneic reflex in anesthetized rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20060801

Title: Effect of intracochlear perfusion of vanilloids on cochlear neural activity in the guinea pig.

Journal: Hearing research 20060801

Title: Characterization of acid signaling in rat vagal pulmonary sensory neurons.

Journal: American journal of physiology. Lung cellular and molecular physiology 20060701

Title: Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in rats.

Journal: Journal of neurochemistry 20060701

Title: Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum.

Journal: Gastroenterology 20060701

Title: Expression and characteristics of vanilloid receptor 1 in the rabbit submandibular gland.

Journal: Biochemical and biophysical research communications 20060623

Title: Modulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor AM404 [N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide].

Journal: The Journal of pharmacology and experimental therapeutics 20060601

Title: Ethanol dilates coronary arteries and increases coronary flow via transient receptor potential vanilloid 1 and calcitonin gene-related peptide.

Journal: Cardiovascular research 20060601

Title: Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats.

Journal: Thrombosis and haemostasis 20060601

Title: Tactile allodynia initiated by local subcutaneous endothelin-1 is prolonged by activation of TRPV-1 receptors.

Journal: Experimental biology and medicine (Maywood, N.J.) 20060601

Title: Gastro-protective action of lafutidine mediated by capsaicin-sensitive afferent neurons without interaction with TRPV1 and involvement of endogenous prostaglandins.

Journal: World journal of gastroenterology 20060521

Title: Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Caged vanilloid ligands for activation of TRPV1 receptors by 1- and 2-photon excitation.

Journal: Biochemistry 20060418

Title: Pharmacological characterisation of the plant sesquiterpenes polygodial and drimanial as vanilloid receptor agonists.

Journal: Biochemical pharmacology 20060414

Title: Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060401

Title: Cannabidiol-induced intracellular Ca2+ elevations in hippocampal cells.

Journal: Neuropharmacology 20060401

Title: Inhibition of Ih reduces epileptiform activity in rodent hippocampal slices.

Journal: Synapse (New York, N.Y.) 20060401

Title: Participation of the spinal TRPV1 receptors in formalin-evoked pain transduction: a study using a selective TRPV1 antagonist, iodo-resiniferatoxin.

Journal: The Journal of pharmacy and pharmacology 20060401

Title: Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats.

Journal: Pharmacology, biochemistry, and behavior 20060401

Title: Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications.

Journal: Biological psychiatry 20060315

Title: A novel mechanism contributing to development of Dahl salt-sensitive hypertension: role of the transient receptor potential vanilloid type 1.

Journal: Hypertension (Dallas, Tex. : 1979) 20060301

Title: Vanilloid VR1 receptor is involved in rimonabant-induced neuroprotection.

Journal: British journal of pharmacology 20060301

Title: Role of capsaicin-sensitive sensory nerves in mediation of the cardiovascular effects of the essential oil of croton zehntneri leaves in anaesthetized rats.

Journal: Clinical and experimental pharmacology & physiology 20060301

Title: Role of cannabinoid receptors in Delta-9-tetrahydrocannabinol suppression of IL-12p40 in mouse bone marrow-derived dendritic cells infected with Legionella pneumophila.

Journal: European journal of pharmacology 20060217

Title: Vanilloid type 1 receptor and the acid-sensing ion channel mediate acid phosphate activation of muscle afferent nerves in rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20060201

Title: Pain behaviors produced by capsaicin: influence of inflammatory mediators and nerve injury.

Journal: The journal of pain : official journal of the American Pain Society 20060201

Title: Methanandamide hyperpolarizes gastric arteries by stimulation of TRPV1 receptors on perivascular CGRP containing nerves.

Journal: Journal of cardiovascular pharmacology 20060201

Title: Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain.

Journal: Journal of medicinal chemistry 20060126

Title: Analgesic effects of capsazepine and resiniferatoxin on bone cancer pain in mice.

Journal: Neuroscience letters 20060123

Title: Capsaicin-induced, capsazepine-insensitive relaxation of the guinea-pig ileum.

Journal: European journal of pharmacology 20060113

Title: Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum.

Journal: European journal of pharmacology 20060113

Title: Attenuation of acid induced oesophagitis in VR-1 deficient mice.

Journal: Gut 20060101

Title: TRPV1 antagonists elevate cell surface populations of receptor protein and exacerbate TRPV1-mediated toxicities in human lung epithelial cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060101

Title: Activity and expression of the vanilloid receptor 1 (TRPV1) is altered by long-term diabetes in epineurial arterioles of the rat sciatic nerve.

Journal: Diabetes/metabolism research and reviews 20060101

Title: Facilitation and inhibition by capsaicin of cholinergic neurotransmission in the guinea-pig small intestine.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060101

Title: Stimulation by bradykinin of HCO3- secretion in rat gastroduodenal mucosa.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20060101

Title: Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin.

Journal: Apoptosis : an international journal on programmed cell death 20060101

Title: Effects of bee venom peptidergic components on rat pain-related behaviors and inflammation.

Journal: Neuroscience 20060101

Title: Depression of presynaptic excitation by the activation of vanilloid receptor 1 in the rat spinal dorsal horn revealed by optical imaging.

Journal: Molecular pain 20060101

Title: Effect of N-arachidonoyl-(2-methyl-4-hydroxyphenyl) amine (VDM11), an anandamide transporter inhibitor, on capsaicin-induced cough in mice.

Journal: Cough (London, England) 20060101

Title: Capsaicin-resistant arterial baroreceptors.

Journal: Journal of negative results in biomedicine 20060101

Title: Spinal afferent neurons projecting to the rat lung and pleura express acid sensitive channels.

Journal: Respiratory research 20060101

Title: The mu opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway.

Journal: Molecular pain 20060101

Title: TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitized guinea pigs.

Journal: Cough (London, England) 20060101

Title: A nonpungent component of steamed ginger--[10]-shogaol--increases adrenaline secretion via the activation of TRPV1.

Journal: Nutritional neuroscience 20060101

Title: Recent advances in basic neurosciences and brain disease: from synapses to behavior.

Journal: Molecular pain 20060101

Title: Molecular cloning, functional characterization of the porcine transient receptor potential V1 (pTRPV1) and pharmacological comparison with endogenous pTRPV1.

Journal: Biochemical pharmacology 20051219

Title: Capsaicin evokes hypothermia independent of cannabinoid CB1 and CB2 receptors.

Journal: Brain research 20051214

Title: TRPV1 gene knockout impairs postischemic recovery in isolated perfused heart in mice.

Journal: Circulation 20051206

Title: Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs.

Journal: The Journal of physiology 20051201

Title: The endocannabinoid arachidonyl ethanolamide (anandamide) increases pulmonary arterial pressure via cyclooxygenase-2 products in isolated rabbit lungs.

Journal: American journal of physiology. Heart and circulatory physiology 20051201

Title: Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla.

Journal: Neuropharmacology 20051201

Title: Proton activation does not alter antagonist interaction with the capsaicin-binding pocket of TRPV1.

Journal: Molecular pharmacology 20051201

Title: The odontoblast as a sensory receptor cell? The expression of TRPV1 (VR-1) channels.

Journal: Archives of histology and cytology 20051201

Title: TRPV1 desensitisation and endogenous vanilloid involvement in the enhanced analgesia induced by capsaicin in inflamed tissues.

Journal: Brain research bulletin 20051130

Title: The mechanosensitivity of mouse colon afferent fibers and their sensitization by inflammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051123

Title: Anandamide suppression of Na+ currents in rat dorsal root ganglion neurons.

Journal: Brain research 20051116

Title: Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis.

Journal: Neurobiology of disease 20051101

Title: Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed.

Journal: The Journal of physiology 20051015

Title: Mechanisms underlying capsaicin-stimulated secretion in the stomach: comparison with mucosal acidification.

Journal: The Journal of pharmacology and experimental therapeutics 20051001

Title: Icilin activates the delta-subunit of the human epithelial Na+ channel.

Journal: Molecular pharmacology 20051001

Title: TRPV1 activation results in disruption of the blood-brain barrier in the rat.

Journal: British journal of pharmacology 20051001

Title: Diuresis and natriuresis caused by activation of VR1-positive sensory nerves in renal pelvis of rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20051001

Title: Inhibitors of fatty acid amide hydrolase reduce carrageenan-induced hind paw inflammation in pentobarbital-treated mice: comparison with indomethacin and possible involvement of cannabinoid receptors.

Journal: British journal of pharmacology 20051001

Title: Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction.

Journal: Journal of cell science 20051001

Title: VR1-mediated depressor effects during high-salt intake: role of anandamide.

Journal: Hypertension (Dallas, Tex. : 1979) 20051001

Title: Cooling-induced contraction of the rat gastric fundus: mediation via transient receptor potential (TRP) cation channel TRPM8 receptor and Rho-kinase activation.

Journal: Clinical and experimental pharmacology & physiology 20051001

Title: Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050928

Title: Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists.

Journal: Bioorganic & medicinal chemistry letters 20050915

Title: Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists.

Journal: Bioorganic & medicinal chemistry letters 20050915

Title: Activation of transient receptor potential vanilloid 1 (TRPV1) by resiniferatoxin.

Journal: The Journal of physiology 20050915

Title: Effects of the novel TRPV1 receptor antagonist SB366791 in vitro and in vivo in the rat.

Journal: Neuroscience letters 20050909

Title: Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity.

Journal: Molecular pharmacology 20050901

Title: Type II vanilloid receptor signaling system: one of the possible mechanisms for the rise in asthma cases.

Journal: Frontiers in bioscience : a journal and virtual library 20050901

Title: Characteristics of propofol-evoked vascular pain in anaesthetized rats.

Journal: British journal of anaesthesia 20050901

Title: Vascular effects of anandamide and N-acylvanillylamines in the human forearm and skin microcirculation.

Journal: British journal of pharmacology 20050901

Title: Heat and mechanical hyperalgesia in mice model of cancer pain.

Journal: Pain 20050901

Title: Multiple types of sensory neurons respond to irritating volatile organic compounds (VOCs): calcium fluorimetry of trigeminal ganglion neurons.

Journal: Pain 20050901

Title: Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice.

Journal: Pain 20050901

Title: Eugenol inhibits calcium currents in dental afferent neurons.

Journal: Journal of dental research 20050901

Title: Conservation of functional and pharmacological properties in the distantly related temperature sensors TRVP1 and TRPM8.

Journal: Molecular pharmacology 20050801

Title: Hydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airways.

Journal: British journal of pharmacology 20050801

Title: Capsazepine, a vanilloid receptor antagonist, inhibits allergen-induced tracheal contraction.

Journal: European journal of pharmacology 20050725

Title: The taming of capsaicin. Reversal of the vanilloid activity of N-acylvanillamines by aromatic iodination.

Journal: Journal of medicinal chemistry 20050714

Title: Vanilloid receptor expressed in the sarcoplasmic reticulum of rat skeletal muscle.

Journal: Biochemical and biophysical research communications 20050708

Title: Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat.

Journal: European journal of pharmacology 20050704

Title: A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel and selective transient receptor potential type V1 receptor antagonist, blocks channel activation by vanilloids, heat, and acid.

Journal: The Journal of pharmacology and experimental therapeutics 20050701

Title: Characterization of rat transient receptor potential vanilloid 1 receptors lacking the N-glycosylation site N604.

Journal: Neuroreport 20050621

Title: Sensory transduction of pulmonary reactive oxygen species by capsaicin-sensitive vagal lung afferent fibres in rats.

Journal: The Journal of physiology 20050601

Title: The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.

Journal: British journal of pharmacology 20050601

Title: Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors.

Journal: Neuropharmacology 20050601

Title: Evidence that (-)-7-hydroxy-4'-dimethylheptyl-cannabidiol activates a non-CB(1), non-CB(2), non-TRPV1 target in the mouse vas deferens.

Journal: Neuropharmacology 20050601

Title: Expression of the transient receptor potential vanilloid 1 (TRPV1) in LNCaP and PC-3 prostate cancer cells and in human prostate tissue.

Journal: European journal of pharmacology 20050516

Title: Hyperthermia increases sensitivity of pulmonary C-fibre afferents in rats.

Journal: The Journal of physiology 20050515

Title: 2-aminoethoxydiphenyl borate stimulates pulmonary C neurons via the activation of TRPV channels.

Journal: American journal of physiology. Lung cellular and molecular physiology 20050501

Title: Characterization and comparison of recombinant human and rat TRPV1 receptors: effects of exo- and endocannabinoids.

Journal: British journal of anaesthesia 20050501

Title: Cannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptamine1A receptor-dependent mechanism.

Journal: Stroke 20050501

Title: The protective effects of rutaecarpine on gastric mucosa injury in rats.

Journal: Planta medica 20050501

Title: Cloning and functional characterization of dog transient receptor potential vanilloid receptor-1 (TRPV1).

Journal: European journal of pharmacology 20050418

Title: Oleoylethanolamide excites vagal sensory neurones, induces visceral pain and reduces short-term food intake in mice via capsaicin receptor TRPV1.

Journal: The Journal of physiology 20050415

Title: Differential responses of bladder lumbosacral and thoracolumbar dorsal root ganglion neurons to purinergic agonists, protons, and capsaicin.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413

Title: Protective effects of Delta(9)-tetrahydrocannabinol against N-methyl-d-aspartate-induced AF5 cell death.

Journal: Brain research. Molecular brain research 20050404

Title: AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties.

Journal: The Journal of pharmacology and experimental therapeutics 20050401

Title: TRPV1b, a functional human vanilloid receptor splice variant.

Journal: Molecular pharmacology 20050401

Title: Transient receptor potential vanilloid (TRPV-1) promotes neurogenic inflammation in the pancreas via activation of the neurokinin-1 receptor (NK-1R).

Journal: Pancreas 20050401

Title: Role of sensory neuron in reduction of endotoxin-induced hypotension in rats.

Journal: Critical care medicine 20050401

Title: Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist.

Journal: Journal of medicinal chemistry 20050324

Title: Acid-sensing properties in rat gastric sensory neurons from normal and ulcerated stomach.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050309

Title: Capsazepine, a vanilloid antagonist, abolishes tonic responses induced by 20-HETE on guinea pig airway smooth muscle.

Journal: American journal of physiology. Lung cellular and molecular physiology 20050301

Title: Capsaicin exhibits neuroprotective effects in a model of transient global cerebral ischemia in Mongolian gerbils.

Journal: British journal of pharmacology 20050301

Title: Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1).

Journal: British journal of pharmacology 20050301

Title: CB(1) cannabinoid receptor stimulation modulates transient receptor potential vanilloid receptor 1 activities in calcium influx and substance P Release in cultured rat dorsal root ganglion cells.

Journal: Journal of pharmacological sciences 20050301

Title: Pharmacological investigation of hydrogen sulfide (H2S) contractile activity in rat detrusor muscle.

Journal: European journal of pharmacology 20050221

Title: Involvement of CGRP in the inhibitory effect of rutaecarpine on vasoconstriction induced by anaphylaxis in guinea pig.

Journal: Regulatory peptides 20050215

Title: A biochemical and pharmacological examination of Rhamphiophis oxyrhynchus (Rufous beaked snake) venom.

Journal: Toxicon : official journal of the International Society on Toxinology 20050201

Title: Vagal selective effects of ruthenium red on the jejunal afferent fibre response to ischaemia in the rat.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20050201

Title: Involvement of peroxynitrite in capsaicin-induced apoptosis of C6 glioma cells.

Journal: Neuroscience research 20050201

Title: AM404, an inhibitor of anandamide reuptake decreases Fos-immunoreactivity in the spinal cord of neuropathic rats after non-noxious stimulation.

Journal: European journal of pharmacology 20050131

Title: Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew).

Journal: European journal of pharmacology 20050131

Title: Transient receptor potential vanilloid subtype 1 mediates cell death of mesencephalic dopaminergic neurons in vivo and in vitro.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050119

Title: Discovery of potent, orally available vanilloid receptor-1 antagonists. Structure-activity relationship of N-aryl cinnamides.

Journal: Journal of medicinal chemistry 20050113

Title: Early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1.

Journal: The Journal of biological chemistry 20050107

Title: Role of capsaicin-sensitive primary afferent inputs from the masseter muscle in the C1 spinal neurons responding to tooth-pulp stimulation in rats.

Journal: Experimental brain research 20050101

Title: Contribution of capsaicin-sensitive sensory neurons to antithrombin-induced reduction of ischemia/reperfusion-induced liver injury in rats.

Journal: Thrombosis and haemostasis 20050101

Title: Lafutidine-induced increase in intracellular ca(2+) concentrations in PC12 and endothelial cells.

Journal: Journal of pharmacological sciences 20050101

Title: A phospholipase C-dependent intracellular Ca2+ release pathway mediates the capsaicin-induced apoptosis in HepG2 human hepatoma cells.

Journal: Archives of pharmacal research 20050101

Title: How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation.

Journal: Molecular pain 20050101

Title: Multiple-signaling pathways are involved in the inhibitory effects of galangin on urinary bladder contractility.

Journal: Neurourology and urodynamics 20050101

Title: Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells.

Journal: Journal of biochemical and molecular toxicology 20050101

Title: Inflammatory mediators convert anandamide into a potent activator of the vanilloid type 1 transient receptor potential receptor in nociceptive primary sensory neurons.

Journal: Neuroscience 20050101

Title: Contrasting phenotypes of putative proprioceptive and nociceptive trigeminal neurons innervating jaw muscle in rat.

Journal: Molecular pain 20050101

Title: Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041215

Title: Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors.

Journal: Brain research. Molecular brain research 20041206

Title: Expression of vanilloid VR1 receptor in PC12 cells.

Journal: Neurochemistry international 20041201

Title: Distinct thymocyte subsets express the vanilloid receptor VR1 that mediates capsaicin-induced apoptotic cell death.

Journal: Cell death and differentiation 20041201

Title: Lipopolysaccharide fever is initiated via a capsaicin-sensitive mechanism independent of the subtype-1 vanilloid receptor.

Journal: British journal of pharmacology 20041201

Title: Current perspectives on the therapeutic utility of VR1 antagonists.

Journal: Current medicinal chemistry 20041201

Title: Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20041201

Title: Protective effects of evodiamine on myocardial ischemia-reperfusion injury in rats.

Journal: Planta medica 20041201

Title: Combined determination with functional and morphological studies of origin of nerve fibers expressing transient receptor potential vanilloid 1 in the myenteric plexus of the rat jejunum.

Journal: Autonomic neuroscience : basic & clinical 20041130

Title: Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells.

Journal: Cancer research 20041115

Title: Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction.

Journal: Circulation research 20041112

Title: Cloning and pharmacological characterization of mouse TRPV1.

Journal: Neuroscience letters 20041103

Title: Muscle pressor reflex: potential role of vanilloid type 1 receptor and acid-sensing ion channel.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20041101

Title: Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice.

Journal: The Journal of physiology 20041101

Title: Perivascular nerves induce cardiorespiratory reflexes in response to algogens in anaesthetised rats.

Journal: Neuroscience research 20041101

Title: Inhibition of the vanilloid receptor subtype-1 attenuates TNBS-colitis.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20041101

Title: Capsazepine is a novel activator of the delta subunit of the human epithelial Na+ channel.

Journal: The Journal of biological chemistry 20041022

Title: Capsazepine elevates intracellular Ca2+ in human osteosarcoma cells, questioning its selectivity as a vanilloid receptor antagonist.

Journal: Life sciences 20041008

Title: Characterization of the human HCN1 channel and its inhibition by capsazepine.

Journal: British journal of pharmacology 20041001

Title: Ischemic preconditioning of remote organs attenuates gastric ischemia-reperfusion injury through involvement of prostaglandins and sensory nerves.

Journal: European journal of pharmacology 20040919

Title: Stimulation of calcitonin gene-related peptide synthesis and release: mechanisms for a novel antihypertensive drug, rutaecarpine.

Journal: Journal of hypertension 20040901

Title: Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation.

Journal: British journal of pharmacology 20040901

Title: Antitussive activity of iodo-resiniferatoxin in guinea pigs.

Journal: Thorax 20040901

Title: Nociceptin inhibits vanilloid TRPV-1-mediated neurosensitization induced by fenoterol in human isolated bronchi.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040901

Title: AM404 enhances the spontaneous release of L-glutamate in a manner sensitive to capsazepine in adult rat substantia gelatinosa neurones.

Journal: Brain research 20040827

Title: Evodiamine functions as an agonist for the vanilloid receptor TRPV1.

Journal: Organic & biomolecular chemistry 20040821

Title: Regulation of calcitonin gene-related peptide release from rat trigeminal nucleus caudalis slices in vitro.

Journal: Neuroscience letters 20040819

Title: Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats.

Journal: Biochemical and biophysical research communications 20040813

Title: Anandamide transport inhibitor AM404 and structurally related compounds inhibit synaptic transmission between rat hippocampal neurons in culture independent of cannabinoid CB1 receptors.

Journal: European journal of pharmacology 20040802

Title: Functional TRPV4 channels are expressed in human airway smooth muscle cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20040801

Title: Vanilloid receptors mediate adrenergic nerve- and CGRP-containing nerve-dependent vasodilation induced by nicotine in rat mesenteric resistance arteries.

Journal: British journal of pharmacology 20040801

Title: Inhibition by anandamide and synthetic cannabimimetics of the release of [3H]D-aspartate and [3H]GABA from synaptosomes isolated from the rat hippocampus.

Journal: Neurochemical research 20040801

Title: Anandamide acts as a vasodilator of dural blood vessels in vivo by activating TRPV1 receptors.

Journal: British journal of pharmacology 20040801

Title: The cannabinomimetic arachidonyl-2-chloroethylamide (ACEA) acts on capsaicin-sensitive TRPV1 receptors but not cannabinoid receptors in rat joints.

Journal: British journal of pharmacology 20040801

Title: [Functional analysis of acid sensing ion channels].

Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20040801

Title: Discovery of small molecule antagonists of TRPV1.

Journal: Bioorganic & medicinal chemistry letters 20040716

Title: TRPV channels and modulation by hepatocyte growth factor/scatter factor in human hepatoblastoma (HepG2) cells.

Journal: Cell calcium 20040701

Title: The mammalian amiloride-insensitive non-specific salt taste receptor is a vanilloid receptor-1 variant.

Journal: The Journal of physiology 20040701

Title: TRPV1 and CB(1) receptor-mediated effects of the endovanilloid/endocannabinoid N-arachidonoyl-dopamine on primary afferent fibre and spinal cord neuronal responses in the rat.

Journal: The European journal of neuroscience 20040701

Title: Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.

Journal: Urology 20040701

Title: N-isoquinolin-5-yl-N'-aralkyl-urea and -amide antagonists of human vanilloid receptor 1.

Journal: Bioorganic & medicinal chemistry letters 20040621

Title: Sex-linked differences in the vasorelaxant effects of anandamide in vascular mesenteric beds: role of oestrogens.

Journal: European journal of pharmacology 20040616

Title: Ethanol causes inflammation in the airways by a neurogenic and TRPV1-dependent mechanism.

Journal: The Journal of pharmacology and experimental therapeutics 20040601

Title: Effects of TRPV1 receptor antagonists on stimulated iCGRP release from isolated skin of rats and TRPV1 mutant mice.

Journal: Pain 20040601

Title: Presynaptic cannabinoid CB(1) receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats.

Journal: British journal of pharmacology 20040601

Title: Vanilloid receptor TRPV1 antagonists as the next generation of painkillers. Are we putting the cart before the horse?

Journal: Journal of medicinal chemistry 20040520

Title: Purinergic and vanilloid receptor activation releases glutamate from separate cranial afferent terminals in nucleus tractus solitarius.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040519

Title: The analgesic effect induced by capsaicin is enhanced in inflammatory states.

Journal: Life sciences 20040514

Title: Involvement of vanilloid-like receptors in the effects of anandamide on motor behavior and nigrostriatal dopaminergic activity: in vivo and in vitro evidence.

Journal: Brain research 20040508

Title: Molecular determinants of vanilloid sensitivity in TRPV1.

Journal: The Journal of biological chemistry 20040507

Title: Histamine-induced Ca(2+) influx via the PLA(2)/lipoxygenase/TRPV1 pathway in rat sensory neurons.

Journal: Neuroscience letters 20040506

Title: Activation of capsaicin-sensitive sensory neurons by carvedilol, a nonselective beta-blocker, in spontaneous hypertensive rats.

Journal: The Journal of pharmacology and experimental therapeutics 20040501

Title: Activation of protein kinase C reverses capsaicin-induced calcium-dependent desensitization of TRPV1 ion channels.

Journal: Cell calcium 20040501

Title: Cannabinoid receptor-independent actions of the aminoalkylindole WIN 55,212-2 on trigeminal sensory neurons.

Journal: British journal of pharmacology 20040501

Title: Identification of species-specific determinants of the action of the antagonist capsazepine and the agonist PPAHV on TRPV1.

Journal: The Journal of biological chemistry 20040423

Title: Inhibitory effect of ginger (Zingiber officinale) on rat ileal motility in vitro.

Journal: Life sciences 20040423

Title: N-4-methansulfonamidobenzyl-N'-2-substituted-4-tert-butyl-benzyl thioureas as potent vanilloid receptor antagonistic ligands.

Journal: Bioorganic & medicinal chemistry letters 20040405

Title: Chain-branched 1,3-dibenzylthioureas as vanilloid receptor 1 antagonists.

Journal: Bioorganic & medicinal chemistry letters 20040405

Title: Modulation of trigeminal sensory neuron activity by the dual cannabinoid-vanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide.

Journal: British journal of pharmacology 20040401

Title: Multiple actions of anandamide on neonatal rat cultured sensory neurones.

Journal: British journal of pharmacology 20040401

Title: Protective role of vanilloid receptor type 1 in HCl-induced gastric mucosal lesions in rats.

Journal: Scandinavian journal of gastroenterology 20040401

Title: Characterization of capsaicin-induced, capsazepine-insensitive relaxation of ileal smooth muscle of rats.

Journal: European journal of pharmacology 20040308

Title: Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines.

Journal: The Journal of pharmacology and experimental therapeutics 20040301

Title: TRPV1 receptors mediate particulate matter-induced apoptosis.

Journal: American journal of physiology. Lung cellular and molecular physiology 20040301

Title: Effects of the vanilloid agonist olvanil and antagonist capsazepine on rat behaviors.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20040301

Title: Characterisation of the vasorelaxant properties of the novel endocannabinoid N-arachidonoyl-dopamine (NADA).

Journal: British journal of pharmacology 20040301

Title: Contribution of vanilloid receptors to the overt nociception induced by B2 kinin receptor activation in mice.

Journal: British journal of pharmacology 20040301

Title: Background potassium channel block and TRPV1 activation contribute to proton depolarization of sensory neurons from humans with neuropathic pain.

Journal: The European journal of neuroscience 20040301

Title: An efficient parallel synthesis of capsazepine and capsazepine analogs.

Journal: Combinatorial chemistry & high throughput screening 20040301

Title: An assessment of vascular pain using the flexor reflex in anesthetized rats.

Journal: Methods and findings in experimental and clinical pharmacology 20040301

Title: N-4-Substituted-benzyl-N'-tert-butylbenzyl thioureas as vanilloid receptor ligands: investigation on the role of methanesulfonamido group in antagonistic activity.

Journal: Bioorganic & medicinal chemistry letters 20040209

Title: Design of a high-affinity competitive antagonist of the vanilloid receptor selective for the calcium entry-linked receptor population.

Journal: Molecular pharmacology 20040201

Title: Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay.

Journal: British journal of pharmacology 20040201

Title: 7-Hydroxynaphthalen-1-yl-urea and -amide antagonists of human vanilloid receptor 1.

Journal: Bioorganic & medicinal chemistry letters 20040119

Title: N-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: analysis of structure-activity relationships for the 'C-Region'.

Journal: Bioorganic & medicinal chemistry 20040115

Title: Cannabinoids modulate neuronal firing in the rat basolateral amygdala: evidence for CB1- and non-CB1-mediated actions.

Journal: Neuropharmacology 20040101

Title: Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist.

Journal: Neuropharmacology 20040101

Title: An investigation of the effects of ruthenium red, nitric oxide and endothelin-1 on infrared receptor activity in a crotaline snake.

Journal: Neuroscience 20040101

Title: Proton conductance of human transient receptor potential-vanilloid type-1 expressed in oocytes of Xenopus laevis and in Chinese hamster ovary cells.

Journal: Neuroscience 20040101

Title: Differential pH and capsaicin responses of Griffonia simplicifolia IB4 (IB4)-positive and IB4-negative small sensory neurons.

Journal: Neuroscience 20040101

Title: Capsaicin, a spicy component of hot pepper, induces apoptosis by activation of the peroxisome proliferator-activated receptor gamma in HT-29 human colon cancer cells.

Journal: Journal of medicinal food 20040101

Title: Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects.

Journal: Bioorganic & medicinal chemistry letters 20031215

Title: Contribution of capsaicin-sensitive sensory neurons to stress-induced increases in gastric tissue levels of prostaglandins in rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20031201

Title: A novel neuroimmune mechanism in cannabinoid-mediated attenuation of nerve growth factor-induced hyperalgesia.

Journal: Anesthesiology 20031201

Title: The endogenous cannabinoid, anandamide, activates the hypothalamo-pituitary-adrenal axis in CB1 cannabinoid receptor knockout mice.

Journal: Neuroendocrinology 20031201

Title: Capsazepine protects against neuronal injury caused by oxygen glucose deprivation by inhibiting I(h).

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031105

Title: Capsaicin-sensitive neurogenic sensory vasodilatation in the dura mater of the rat.

Journal: The Journal of physiology 20031101

Title: Signal transduction for inhibition of inducible nitric oxide synthase and cyclooxygenase-2 induction by capsaicin and related analogs in macrophages.

Journal: British journal of pharmacology 20031101

Title: Insulin induces cobalt uptake in a subpopulation of rat cultured primary sensory neurons.

Journal: The European journal of neuroscience 20031101

Title: Thermal properties of acid-induced depolarization in cultured rat small primary afferent neurons.

Journal: Neuroscience letters 20031023

Title: 4-(2-pyridyl)piperazine-1-carboxamides: potent vanilloid receptor 1 antagonists.

Journal: Bioorganic & medicinal chemistry letters 20031020

Title: Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM.

Journal: Journal of neurophysiology 20031001

Title: Hypotensive effect of anandamide through the activation of CB1 and VR1 spinal receptors in urethane-anesthetized rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20031001

Title: A novel capsaicin derivative VOA induced relaxation in rat mesenteric and aortic arteries: involvement of CGRP, NO, cGMP, and endothelium-dependent activities.

Journal: Journal of cardiovascular pharmacology 20031001

Title: Activation of vanilloid receptor 1 (VR1) by eugenol.

Journal: Journal of dental research 20031001

Title: Vanilloid type 1 receptors (VR1) on trigeminal sensory nerve fibres play a minor role in neurogenic dural vasodilatation, and are involved in capsaicin-induced dural dilation.

Journal: British journal of pharmacology 20031001

Title: Vanilloid receptor activation by 2- and 10-microm particles induces responses leading to apoptosis in human airway epithelial cells.

Journal: Toxicology and applied pharmacology 20031001

Title: Cannabinoids inhibit the release of [3H]glutamate from rodent hippocampal synaptosomes via a novel CB1 receptor-independent action.

Journal: The European journal of neuroscience 20031001

Title: Expression of vanilloid receptors in rat gastric epithelial cells: role in cellular protection.

Journal: Biochemical pharmacology 20030915

Title: Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid.

Journal: Biochemical pharmacology 20030901

Title: An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice.

Journal: Gastroenterology 20030901

Title: Stimulation by capsaicin of duodenal HCO3(-) secretion via afferent neurons and vanilloid receptors in rats: comparison with acid-induced HCO3(-) response.

Journal: Digestive diseases and sciences 20030901

Title: Capsaicin-like effects of N-arachidonoyl-dopamine in the isolated guinea pig bronchi and urinary bladder.

Journal: European journal of pharmacology 20030815

Title: Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists.

Journal: British journal of pharmacology 20030802

Title: Increased expression of vanilloid receptor 1 on myelinated primary afferent neurons contributes to the antihyperalgesic effect of capsaicin cream in diabetic neuropathic pain in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20030801

Title: Function and regulation of the vanilloid receptor in rats fed a high salt diet.

Journal: Journal of hypertension 20030801

Title: Involvement of vanilloid receptors in heat stress-induced delayed protection against myocardial ischemia-reperfusion injury.

Journal: Neuropeptides 20030801

Title: Mechanisms of sensitization of the response of single dorsal root ganglion cells from adult rat to noxious heat.

Journal: The European journal of neuroscience 20030801

Title: Proton-induced calcitonin gene-related peptide release from rat sciatic nerve axons, in vitro, involving TRPV1.

Journal: The European journal of neuroscience 20030801

Title: Modifications of capsaicin-sensitive neurons in isolated guinea pig ileum by [6]-gingerol and lafutidine.

Journal: Journal of pharmacological sciences 20030801

Title: Albaconol from the mushroom Albatrellus confluens induces contraction and desensitization in guinea pig trachea.

Journal: Planta medica 20030801

Title: N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.

Journal: Journal of medicinal chemistry 20030703

Title: Vanilloid receptors in hearing: altered cochlear sensitivity by vanilloids and expression of TRPV1 in the organ of corti.

Journal: Journal of neurophysiology 20030701

Title: N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. in vivo characterization in rat models of inflammatory and neuropathic pain.

Journal: The Journal of pharmacology and experimental therapeutics 20030701

Title: N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic properties.

Journal: The Journal of pharmacology and experimental therapeutics 20030701

Title: New evidence on the mechanisms underlying bradykinin-mediated contraction of the pig iris sphincter in vitro.

Journal: Peptides 20030701

Title: Involvement of capsaicin-sensitive sensory nerves in cardioprotection of rutaecarpine in rats.

Journal: Regulatory peptides 20030615

Title: Calcium signaling in single peripheral sensory nerve terminals.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615

Title: The effects of local and intravenous anesthetics on recombinant rat VR1 vanilloid receptors.

Journal: Anesthesia and analgesia 20030601

Title: Electrostatic charge activates inflammatory vanilloid (VR1) receptors.

Journal: Neurotoxicology 20030601

Title: Adrenergic regulation of capsaicin-sensitive neurons in dental pulp.

Journal: Journal of endodontics 20030601

Title: Anandamide induces cell death independently of cannabinoid receptors or vanilloid receptor 1: possible involvement of lipid rafts.

Journal: Cellular and molecular life sciences : CMLS 20030601

Title: Inhibitory effect of the plant flavonoid galangin on rat vas deferens in vitro.

Journal: Life sciences 20030516

Title: Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030515

Title: Chain-branched acyclic phenethylthiocarbamates as vanilloid receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20030505

Title: Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats.

Journal: Gut 20030501

Title: Capsaicin-induced reactivation of latent herpes simplex virus type 1 in sensory neurons in culture.

Journal: The Journal of general virology 20030501

Title: State-dependent phosphorylation of epsilon-isozyme of protein kinase C in adult rat dorsal root ganglia after inflammation and nerve injury.

Journal: Journal of neurochemistry 20030501

Title: Anandamide induces apoptosis in human endothelial cells: its regulation system and clinical implications.

Journal: Thrombosis and haemostasis 20030501

Title: Capsaicinoids cause inflammation and epithelial cell death through activation of vanilloid receptors.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030501

Title: The nociceptive and anti-nociceptive effects of evodiamine from fruits of Evodia rutaecarpa in mice.

Journal: Planta medica 20030501

Title: Peripheral tackykinin and excitatory amino acid receptors mediate hyperalgesia induced by Phoneutria nigriventer venom.

Journal: European journal of pharmacology 20030425

Title: Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug.

Journal: European journal of pharmacology 20030425

Title: Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415

Title: The actions of anandamide on rat superficial medullary dorsal horn neurons in vitro.

Journal: The Journal of physiology 20030401

Title: Differential effects of intraplantar capsazepine and ruthenium red on capsaicin-induced desensitization in mice.

Journal: Pharmacology, biochemistry, and behavior 20030401

Title: Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophages.

Journal: Cellular signalling 20030301

Title: Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease.

Journal: Journal of neurochemistry 20030301

Title: A role for TRPV1 in bradykinin-induced excitation of vagal airway afferent nerve terminals.

Journal: The Journal of pharmacology and experimental therapeutics 20030301

Title: Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor.

Journal: Molecular pharmacology 20030301

Title: Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor.

Journal: Hypertension (Dallas, Tex. : 1979) 20030301

Title: Neurogenic responses mediated by vanilloid receptor-1 (TRPV1) are blocked by the high affinity antagonist, iodo-resiniferatoxin.

Journal: British journal of pharmacology 20030301

Title: Synthesis of N,N',N'-trisubstituted thiourea derivatives and their antagonist effect on the vanilloid receptor.

Journal: Bioorganic & medicinal chemistry letters 20030224

Title: Effect of arvanil (N-arachidonoyl-vanillyl-amine), a nonpungent anandamide-capsaicin hybrid, on ion currents in NG108-15 neuronal cells.

Journal: Biochemical pharmacology 20030215

Title: Versatile regulation of cytosolic Ca2+ by vanilloid receptor I in rat dorsal root ganglion neurons.

Journal: The Journal of biological chemistry 20030214

Title: Endocannabinoids induce ileitis in rats via the capsaicin receptor (VR1).

Journal: The Journal of pharmacology and experimental therapeutics 20030201

Title: The depressor and vasodilator effects of rutaecarpine are mediated by calcitonin gene-related peptide.

Journal: Planta medica 20030201

Title: Synthesis of 2-substituted-pyrrolidinethiourea derivatives and their antagonist effect on vanilloid receptor.

Journal: Bioorganic & medicinal chemistry letters 20030120

Title: Concentration-dependent dual effect of anandamide on sensory neuropeptide release from isolated rat tracheae.

Journal: Neuroscience letters 20030116

Title: Negatively charged 2- and 10-microm particles activate vanilloid receptors, increase cAMP, and induce cytokine release.

Journal: Toxicology and applied pharmacology 20030115

Title: R+-methanandamide inhibits tracheal response to endogenously released acetylcholine via capsazepine-sensitive receptors.

Journal: European journal of pharmacology 20030110

Title: The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain.

Journal: The Journal of pharmacology and experimental therapeutics 20030101

Title: Potentiation of anandamide effects in mesenteric beds isolated from endotoxemic rats.

Journal: The Journal of pharmacology and experimental therapeutics 20030101

Title: Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20030101

Title: Neurokinin release produced by capsaicin acting on the central terminals and axons of primary afferents: relationship with N-methyl-D-aspartate and GABA(B) receptors.

Journal: Neuroscience 20030101

Title: Functional properties of the high-affinity TRPV1 (VR1) vanilloid receptor antagonist (4-hydroxy-5-iodo-3-methoxyphenylacetate ester) iodo-resiniferatoxin.

Journal: The Journal of pharmacology and experimental therapeutics 20021201

Title: Comparison of effects of anandamide at recombinant and endogenous rat vanilloid receptors.

Journal: British journal of anaesthesia 20021201

Title: Effect of olvanil (N-vanillyl-cis-9-octadecenoamide) on cytosolic Ca2+ increase in renal tubular cells.

Journal: Life sciences 20021115

Title: Upregulation of proinflammatory cytokines and nerve growth factor by intraplantar injection of capsaicin in rats.

Journal: The Journal of physiology 20021115

Title: Characterization of the vanilloid receptor 1 antagonist iodo-resiniferatoxin on the afferent and efferent function of vagal sensory C-fibers.

Journal: The Journal of pharmacology and experimental therapeutics 20021101

Title: Gingerols: a novel class of vanilloid receptor (VR1) agonists.

Journal: British journal of pharmacology 20021101

Title: Anandamide induces cough in conscious guinea-pigs through VR1 receptors.

Journal: British journal of pharmacology 20021101

Title: Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors.

Journal: The Journal of clinical investigation 20021015

Title: High affinity antagonists of the vanilloid receptor.

Journal: Molecular pharmacology 20021001

Title: Anandamide is a partial agonist at native vanilloid receptors in acutely isolated mouse trigeminal sensory neurons.

Journal: British journal of pharmacology 20021001

Title: Cellular mechanisms of nociception in the frog.

Journal: Journal of neurophysiology 20021001

Title: The putative role of vanilloid receptor-like protein-1 in mediating high threshold noxious heat-sensitivity in rat cultured primary sensory neurons.

Journal: The European journal of neuroscience 20021001

Title: Use of a fluorescent imaging plate reader--based calcium assay to assess pharmacological differences between the human and rat vanilloid receptor.

Journal: Journal of biomolecular screening 20021001

Title: Effect of piperine, the active ingredient of black pepper, on intestinal secretion in mice.

Journal: Life sciences 20020927

Title: Protein kinase C(alpha) is required for vanilloid receptor 1 activation. Evidence for multiple signaling pathways.

Journal: The Journal of biological chemistry 20020920

Title: Vanilloid receptors presynaptically modulate cranial visceral afferent synaptic transmission in nucleus tractus solitarius.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020915

Title: Mechanisms underlying tissue selectivity of anandamide and other vanilloid receptor agonists.

Journal: Molecular pharmacology 20020901

Title: Characterization of the anandamide induced depolarization of guinea-pig isolated vagus nerve.

Journal: British journal of pharmacology 20020901

Title: Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901

Title: Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901

Title: Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus in vitro.

Journal: The Journal of physiology 20020901

Title: Mechanisms of acid-induced activation of airway afferent nerve fibres in guinea-pig.

Journal: The Journal of physiology 20020901

Title: Cloning and functional characterization of the guinea pig vanilloid receptor 1.

Journal: Neuropharmacology 20020901

Title: Pharmacological separation of cannabinoid sensitive receptors on hippocampal excitatory and inhibitory fibers.

Journal: Neuropharmacology 20020901

Title: Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells.

Journal: The Biochemical journal 20020815

Title: The cardioprotection of rutaecarpine is mediated by endogenous calcitonin related-gene peptide through activation of vanilloid receptors in guinea-pig hearts.

Journal: Planta medica 20020801

Title: Effects of peripheral nerve injury on functional spinal VR1 receptors.

Journal: Neuroreport 20020702

Title: Activation of protein kinase C sensitizes human VR1 to capsaicin and to moderate decreases in pH at physiological temperatures in Xenopus oocytes.

Journal: Pain 20020701

Title: A heat-sensitive TRP channel expressed in keratinocytes.

Journal: Science (New York, N.Y.) 20020614

Title: Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1.

Journal: Nature neuroscience 20020601

Title: Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent.

Journal: American journal of physiology. Heart and circulatory physiology 20020601

Title: The arginine-rich hexapeptide R4W2 is a stereoselective antagonist at the vanilloid receptor 1: a Ca2+ imaging study in adult rat dorsal root ganglion neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20020601

Title: DRASIC contributes to pH-gated currents in large dorsal root ganglion sensory neurons by forming heteromultimeric channels.

Journal: Journal of neurophysiology 20020601

Title: Capsazepine inhibits thermal hyperalgesia but not nociception triggered by protease-activated receptor-2 in rats.

Journal: Japanese journal of pharmacology 20020601

Title: Contractile response to a cannabimimetic eicosanoid, 2-arachidonoylglycerol, of longitudinal smooth muscle from the guinea-pig distal colon in vitro.

Journal: European journal of pharmacology 20020531

Title: Comparison of capsaicin-evoked calcium transients between rat nodose and jugular ganglion neurons.

Journal: Autonomic neuroscience : basic & clinical 20020531

Title: Spinal administration of capsazepine inhibits noxious evoked responses of dorsal horn neurons in non-inflamed and carrageenan inflamed rats.

Journal: Brain research 20020510

Title: 3-D-QSAR analysis of N-(3-acyloxy-2-benzylpropyl)-N'-dihydroxytetrahydrobenzazepine and tetrahydroisoquinoline and N-(3-acyloxy-2-benzylpropyl)-N'-(4-hydroxy-3-methoxybenzyl) thioureas analogues as potent vanilloid receptor ligands.

Journal: Bioorganic & medicinal chemistry 20020501

Title: Gastric hyperemic response induced by acid back-diffusion in rat stomachs following barrier disruption -- relation to vanilloid type-1 receptors.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Capsazepine partially inhibits neurally mediated gastric mucus secretion following activation of protease-activated receptor 2.

Journal: Clinical and experimental pharmacology & physiology 20020401

Title: Ischemia/reperfusion-induced increase in the hepatic level of prostacyclin is mainly mediated by activation of capsaicin-sensitive sensory neurons in rats.

Journal: The Journal of laboratory and clinical medicine 20020401

Title: Interaction between vanilloid and glutamate receptors in the central modulation of nociception.

Journal: European journal of pharmacology 20020329

Title: Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors.

Journal: European journal of pharmacology 20020329

Title: Stimulation of pulmonary vagal C-fibres by anandamide in anaesthetized rats: role of vanilloid type 1 receptors.

Journal: The Journal of physiology 20020315

Title: Protease-activated receptor-2 activation causes EDHF-like coronary vasodilation: selective preservation in ischemia/reperfusion injury: involvement of lipoxygenase products, VR1 receptors, and C-fibers.

Journal: Circulation research 20020308

Title: Evidence of a novel site mediating anandamide-induced negative inotropic and coronary vasodilatator responses in rat isolated hearts.

Journal: British journal of pharmacology 20020301

Title: Relaxant effect of capsazepine in the isolated rat ileum.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020301

Title: Functional vanilloid receptors in cultured normal human epidermal keratinocytes.

Journal: Biochemical and biophysical research communications 20020215

Title: Particulate matter inflammation and receptor sensitivity are target cell specific.

Journal: Inhalation toxicology 20020201

Title: Pharmacological characterization of vanilloid receptor located in the brain.

Journal: Brain research. Molecular brain research 20020131

Title: Simultaneous intracellular calcium and sodium flux imaging in human vanilloid receptor 1 (VR1)-transfected human embryonic kidney cells: a method to resolve ionic dependence of VR1-mediated cell death.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Activation of capsaicin receptors on the sciatic nerve induces FOS expression in the spinal dorsal horn of adult rats.

Journal: Neuro-Signals 20020101

Title: Effects of ginsenosides on vanilloid receptor (VR1) channels expressed in Xenopus oocytes.

Journal: Molecules and cells 20011231

Title: Acidic stimuli activates two distinct pathways in taste receptor cells from rat fungiform papillae.

Journal: Brain research 20011227

Title: Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20011201

Title: The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice.

Journal: Neuropharmacology 20011201

Title: Anandamide and methanandamide induce both vanilloid VR1- and cannabinoid CB1 receptor-mediated changes in heart rate and blood pressure in anaesthetized rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20011201

Title: Involvement of vanilloid receptor VR1 and prostanoids in the acid-induced writhing responses of mice.

Journal: Life sciences 20011102

Title: Capsaicin vanilloid receptor-1 mediates substance P release in experimental pancreatitis.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20011101

Title: Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels.

Journal: British journal of pharmacology 20011101

Title: Capsaicin-, resiniferatoxin-, and olvanil-induced adrenaline secretions in rats via the vanilloid receptor.

Journal: Bioscience, biotechnology, and biochemistry 20011101

Title: Propofol activates vanilloid receptor channels expressed in human embryonic kidney 293 cells.

Journal: Neuroscience letters 20011012

Title: Stimulatory effect of centrally injected capsaicin, an agonist of vanilloid receptors, on gastric acid secretion in rats.

Journal: European journal of pharmacology 20011012

Title: Capsaicin inhibits Jurkat T-cell activation by blocking calcium entry current I(CRAC).

Journal: The Journal of pharmacology and experimental therapeutics 20011001

Title: Pharmacological modulation of monovalent cation currents through the epithelial Ca2+ channel ECaC1.

Journal: British journal of pharmacology 20011001

Title: Anandamide induces cardiovascular and respiratory reflexes via vasosensory nerves in the anaesthetized rat.

Journal: British journal of pharmacology 20011001

Title: Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide.

Journal: British journal of pharmacology 20011001

Title: Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries.

Journal: British journal of pharmacology 20011001

Title: Capsaicin-evoked CGRP release from rat buccal mucosa: development of a model system for studying trigeminal mechanisms of neurogenic inflammation.

Journal: The European journal of neuroscience 20011001

Title: Noxious heat-induced CGRP release from rat sciatic nerve axons in vitro.

Journal: The European journal of neuroscience 20011001

Title: Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed.

Journal: European journal of pharmacology 20010921

Title: The capsaicin VR1 receptor mediates substance P release in toxin A-induced enteritis in rats.

Journal: Peptides 20010901

Title: A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus.

Journal: British journal of pharmacology 20010901

Title: Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors.

Journal: British journal of pharmacology 20010901

Title: Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1.

Journal: The Journal of biological chemistry 20010817

Title: Effects of capsaicin on Ca(2+) release from the intracellular Ca(2+) stores in the dorsal root ganglion cells of adult rats.

Journal: Biochemical and biophysical research communications 20010803

Title: Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide.

Journal: The Journal of physiology 20010801

Title: CH-19 sweet, nonpungent cultivar of red pepper, increased body temperature in mice with vanilloid receptors stimulation by capsiate.

Journal: Journal of nutritional science and vitaminology 20010801

Title: Analysis of the native quaternary structure of vanilloid receptor 1.

Journal: The Journal of biological chemistry 20010727

Title: Cannabinoid activation of recombinant and endogenous vanilloid receptors.

Journal: European journal of pharmacology 20010727

Title: Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide.

Journal: European journal of pharmacology 20010706

Title: Effects of capsaicin on human intestinal cell line Caco-2.

Journal: Cytotechnology 20010701

Title: Genital grooming and emesis induced by vanilloids in Suncus murinus, the house musk shrew.

Journal: European journal of pharmacology 20010622

Title: Vanilloid receptor expression and capsaicin excitation of rat dental primary afferent neurons.

Journal: Journal of dental research 20010601

Title: Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues.

Journal: European journal of pharmacology 20010525

Title: Capsaicin-induced relaxation in rabbit coronary artery.

Journal: The Journal of veterinary medical science 20010501

Title: Mechanism of atropine-resistant contraction induced by Dai-kenchu-to in guinea pig ileum.

Journal: Japanese journal of pharmacology 20010501

Title: The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism.

Journal: The Journal of biological chemistry 20010420

Title: Low pH modulation of recombinant vanilloid receptors and perivascular capsaicin-sensitive sensory neurotransmission.

Journal: Autonomic neuroscience : basic & clinical 20010412

Title: Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology.

Journal: European journal of pharmacology 20010406

Title: Effect of vanilloid drugs on gastrointestinal transit in mice.

Journal: British journal of pharmacology 20010401

Title: Capsaicin-evoked release of immunoreactive calcitonin gene-related peptide from rat trigeminal ganglion: evidence for intraganglionic neurotransmission.

Journal: Pain 20010401

Title: The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: possible involvement of vanilloid receptors.

Journal: Planta medica 20010401

Title: Capsazepine, a vanilloid receptor antagonist, inhibits the expression of inducible nitric oxide synthase gene in lipopolysaccharide-stimulated RAW264.7 macrophages through the inactivation of nuclear transcription factor-kappa B.

Journal: International immunopharmacology 20010401

Title: Sensory pathways and cyclooxygenase regulate mucus gel thickness in rat duodenum.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010301

Title: Pharmacological differences between the human and rat vanilloid receptor 1 (VR1).

Journal: British journal of pharmacology 20010301

Title: The endogenous cannabinoid agonist, anandamide stimulates sensory nerves in guinea-pig airways.

Journal: British journal of pharmacology 20010301

Title: Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010215

Title: Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints.

Journal: British journal of pharmacology 20010201

Title: Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens.

Journal: British journal of pharmacology 20010201

Title: Capsaicin inhibits activation of voltage-gated sodium currents in capsaicin-sensitive trigeminal ganglion neurons.

Journal: Journal of neurophysiology 20010201

Title: Regional differences in anandamide- and methanandamide-induced membrane potential changes in rat mesenteric arteries.

Journal: The Journal of pharmacology and experimental therapeutics 20010201

Title: ACTH inhibits the capsaicin-evoked release of CGRP from rat adrenal afferent nerves.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010101

Title: Iodo-resiniferatoxin, a new potent vanilloid receptor antagonist.

Journal: Molecular pharmacology 20010101

Title: Characterization of a novel mechanism accounting for the adverse cholinergic effects of the anticancer drug irinotecan.

Journal: British journal of pharmacology 20010101

Title: Comparison of intracellular calcium signals evoked by heat and capsaicin in cultured rat dorsal root ganglion neurons and in a cell line expressing the rat vanilloid receptor, VR1.

Journal: Neuroscience 20010101

Title: Changes in cytosolic calcium in response to noxious heat and their relationship to vanilloid receptors in rat dorsal root ganglion neurons.

Journal: Neuroscience 20010101

Title: Pharmacology of airway afferent nerve activity.

Journal: Respiratory research 20010101

Title: Induction of vanilloid receptor channel activity by protein kinase C.

Journal: Nature 20001201

Title: Characterization using FLIPR of rat vanilloid receptor (rVR1) pharmacology.

Journal: British journal of pharmacology 20000601

Title: Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20000523

Title: The anandamide transport inhibitor AM404 activates vanilloid receptors.

Journal: European journal of pharmacology 20000512

Title: Involvement of vanilloid receptors and purinoceptors in the Phoneutria nigriventer spider venom-induced plasma extravasation in rat skin.

Journal: European journal of pharmacology 20000317

Title: Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide.

Journal: Nature 19990729

Title: Identification of the L-menthol binding site in guinea-pig lung membranes.

Journal: British journal of pharmacology 19980201

Title: Mechanism of acid-induced mesenteric hyperemia in rats.

Journal: Life sciences 19980101

Title: The selective capsaicin antagonist capsazepine abolishes the antinociceptive action of eugenol and guaiacol.

Journal: Journal of dental research 19970401

Title: Substance P and capsaicin-induced mechanical hyperalgesia in the rat knee joint; the involvement of bradykinin B1 and B2 receptors.

Journal: British journal of pharmacology 19960801

Title: Release of beta-endorphin immunoreactivity into ventriculo-cisternal perfusate by lumbar intrathecal capsaicin in the rat.

Journal: Brain research 19951201

Title: Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: study with on-line continuous monitoring of glutamate.

Journal: Neuroscience research 19940901

Title: Regulation of neuropeptide release from pulmonary capsaicin-sensitive afferents in relation to bronchoconstriction.

Journal: Acta physiologica Scandinavica. Supplementum 19930101

Title: Sung B, et al. Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors. Free Radic Biol Med. 2012 Nov 15;53(10):1977-87.

Title: Santicioli P, et al. Effect of capsazepine on the release of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) induced by low pH, capsaicin and potassium in rat soleus muscle. Br J Pharmacol. 1993 Oct;110(2):609-12.

Title: Cabral LD, et al. The Transient Receptor Potential Vanilloid 1 Antagonist Capsazepine Improves the Impaired Lung Mechanics during Endotoxemia. Basic Clin Pharmacol Toxicol. 2016 Nov;119(5):421-427.

Title: Wang J, et al. Anti-inflammatory and retinal protective effects of capsaicin on ischaemia-induced injuries through the release of endogenous somatostatin. Clin Exp Pharmacol Physiol. 2017 Jul;44(7):803-814.

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