Home PEG Linkers 1391914-41-2
1391914-41-2,MFCD28505558
Catalog No.:AA00HVE6

1391914-41-2 | Propargyl-peg1-ss-alcohol

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Purity
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250mg
98%
in stock  
$2,365.00   $1,655.00
- +
500mg
98%
in stock  
$3,704.00   $2,593.00
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1g
98%
in stock  
$5,525.00   $3,868.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00HVE6
Chemical Name:
Propargyl-peg1-ss-alcohol
CAS Number:
1391914-41-2
Molecular Formula:
C7H12O2S2
Molecular Weight:
192.2990
MDL Number:
MFCD28505558
SMILES:
OCCSSCCOCC#C
Properties
Computed Properties
 
Complexity:
119  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
0.2  

Downstream Synthesis Route

[1]Sun,Guangping;He,Zhimei;Hao,Min;Xu,Zuqiang;Hu,Xiao-Yu;Zhu,Jun-Jie;Wang,Leyong[ChemicalCommunications,2019,vol.55,#73,p.10892-10895]

[2]CurrentPatentAssignee:UNIVERSITYOFCALIFORNIA-WO2018/195078,2018,A1Locationinpatent:Paragraph0028;00502;00509

[3]Li,Yajie;Li,Zhenjie;Liang,Jian;Liu,Feiyang;Luo,Tingrong;Pu,Chunxiao;Wang,Jianyi;Wang,Mian;Yi,Qingyuan[JournalofMedicinalChemistry,2021,vol.64,#19,p.14793-14808]

[4]Li,Lianwei;Wang,Xu;Yang,Jinxian;Ye,Xiaodong;Wu,Chi[Macromolecules,2014,vol.47,#2,p.650-658]

[5]Liu,Xin;Shao,Wei;Zheng,Yanjing;Yao,Chenhao;Peng,Luming;Zhang,Dongmei;Hu,Xiao-Yu;Wang,Leyong[ChemicalCommunications,2017,vol.53,#61,p.8596-8599]

[6]Dhara,Dibakar;Dhara,Santanu;Maiti,Saikat;Maity,Pritiprasanna;Poddar,Puja;Sahoo,Satyagopal[ReactiveandFunctionalPolymers,2020,vol.154]

[7]Dong,Shuxiang;He,Jinlin;Li,Dian;Li,Lei;Ni,Peihong;Sun,Yue;Zhang,Mingzu[MolecularPharmaceutics,2019]

[8]CurrentPatentAssignee:NANJINGUNIVERSITYOFAERONAUTICANDASTRONAUTICS-CN112079684,2020,ALocationinpatent:Paragraph0105;0109-0111

497931-76-7    1391914-41-2   
2-((2-(2-(2-(prop-2-ynyloxy)ethyl)disulfanyl)ethoxy)carbonyl)ethylbenzylcarbonotrithionate 

[1]ReactiveandFunctionalPolymers,2020,vol.154

Literature

Title: Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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SDS
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