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1397922-61-0,MFCD31657349
Catalog No.:AA01EO5G

1397922-61-0 | Pyrotinib dimaleate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$325.00   $228.00
- +
5mg
98%
in stock  
$879.00   $615.00
- +
10mg
98%
in stock  
$1,147.00   $803.00
- +
25mg
98%
in stock  
$1,754.00   $1,228.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EO5G
Chemical Name:
Pyrotinib dimaleate
CAS Number:
1397922-61-0
Molecular Formula:
C40H39ClN6O11
Molecular Weight:
815.2243
MDL Number:
MFCD31657349
SMILES:
OC(=O)/C=C\C(=O)O.OC(=O)/C=C\C(=O)O.CCOc1cc2ncc(c(c2cc1NC(=O)/C=C/[C@H]1CCCN1C)Nc1ccc(c(c1)Cl)OCc1ccccn1)C#N
Properties
Computed Properties
 
Complexity:
1080  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
3  
Heavy Atom Count:
58  
Hydrogen Bond Acceptor Count:
16  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
14  

Literature

Title: Li X, et al. Discovery and development of Pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer. Eur J Pharm Sci. 2017 Jan 21. pii: S0928-0987(17)30043-X.

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SDS
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Tags:1397922-61-0 Molecular Formula|1397922-61-0 MDL|1397922-61-0 SMILES|1397922-61-0 Pyrotinib dimaleate