Name: Name:(S)-(-)-5-IODOWILLARDIINE
Brand: AABLOCKS
SKU: AA009A7U
Rating: 90 (10 reviews)

Catalog No.: AA009A7U

140187-25-3 | (S)-(-)-5-IODOWILLARDIINE

Pack Size： 10mg

Purity： ≥98%(HPLC)

in stock

$293.00 $205.00

Pack Size： 50mg

Purity： ≥98%(HPLC)

in stock

$945.00 $662.00

Pack Size： 100mg

Purity： ≥98%(HPLC)

in stock

$1,656.00 $1,159.00

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Technical Information

Catalog Number: AA009A7U

Chemical Name: (S)-(-)-5-IODOWILLARDIINE

CAS Number: 140187-25-3

Molecular Formula: C7H8IN3O4

Molecular Weight: 325.0606

MDL Number: MFCD00673845

SMILES: OC(=O)[C@H](Cn1cc(I)c(=O)[nH]c1=O)N

Properties

Complexity: 354

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 15

Hydrogen Bond Acceptor Count: 5

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 3

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: -3.7

Literature fold

Title: Structure and assembly mechanism for heteromeric kainate receptors.

Journal: Neuron20110728

Title: Activation of iGluR5 kainate receptors inhibits neurogenic dural vasodilatation in an animal model of trigeminovascular activation.

Journal: British journal of pharmacology20090601

Title: Kainate receptors: pharmacology, function and therapeutic potential.

Journal: Neuropharmacology20090101

Title: 1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. structure-activity relationships and identification of potent and Selective iGluR5 modulators.

Journal: Journal of medicinal chemistry20081023

Title: Synthesis and pharmacology of willardiine derivatives acting as antagonists of kainate receptors.

Journal: Journal of medicinal chemistry20051201

Title: Structural basis for partial agonist action at ionotropic glutamate receptors.

Journal: Nature neuroscience20030801

Title: Contributions of AMPA- and kainate-sensitive receptors to the photopic electroretinogram of the Xenopus retina.

Journal: Visual neuroscience20010101

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