Title: 3D-QSAR and molecular docking studies of 2-pyrimidinecarbonitrile derivatives as inhibitors against falcipain-3.
Journal: Bioorganic & medicinal chemistry letters 20111201
Title: Unprecedented copper(I)-catalyzed in situ double cycloaddition reaction based on 2-cyanopyrimidine.
Journal: Dalton transactions (Cambridge, England : 2003) 20110607
Title: Poly[(μ(2)-nitrato-κO:O')(μ(2)-pyrimidin-ium-2-carboxyl-ato-κO:O')lithium(I)].
Journal: Acta crystallographica. Section E, Structure reports online 20110601
Title: Mining a cathepsin inhibitor library for new antiparasitic drug leads.
Journal: PLoS neglected tropical diseases 20110501
Title: Top-hits for H1N1pdm Identified by Virtual Screening Using Ensemble-based Docking.
Journal: PLoS currents 20110103
Title: Synthesis and characterization of novel 2, 2'-bipyrimidine fluorescent derivative for protein binding.
Journal: Chemistry Central journal 20110101
Title: Protease-associated cellular networks in malaria parasite Plasmodium falciparum.
Journal: BMC genomics 20110101
Title: Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: improving selectivity over hERG.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Mixed azide and 5-(pyrimidyl)tetrazole bridged Co(II)/Mn(II) polymers: synthesis, crystal structures, ferroelectric and magnetic behavior.
Journal: Inorganic chemistry 20100920
Title: Falcipain inhibitors: optimization studies of the 2-pyrimidinecarbonitrile lead series.
Journal: Journal of medicinal chemistry 20100826
Title: 4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important.
Journal: Bioorganic & medicinal chemistry letters 20100801
Title: 6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20100801
Title: Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20100301
Title: The Diels-Alder-reaction with inverse-electron-demand, a very efficient versatile click-reaction concept for proper ligation of variable molecular partners.
Journal: International journal of medical sciences 20100101
Title: Gain of a 500-fold sensitivity on an intravital MR contrast agent based on an endohedral gadolinium-cluster-fullerene-conjugate: a new chance in cancer diagnostics.
Journal: International journal of medical sciences 20100101
Title: A cyclic-RGD-BioShuttle functionalized with TMZ by DARinv 'Click Chemistry' targeted to αvβ3 integrin for therapy.
Journal: International journal of medical sciences 20100101
Title: Overcoming hERG issues for brain-penetrating cathepsin S inhibitors: 2-cyanopyrimidines. Part 2.
Journal: Bioorganic & medicinal chemistry letters 20081001
Title: Ensemble-based virtual screening reveals potential novel antiviral compounds for avian influenza neuraminidase.
Journal: Journal of medicinal chemistry 20080710
Title: Poly[diaqua-μ(2)-oxalato-di-μ(2)-pyrimidine-2-carboxyl-ato-dimanganese(II)].
Journal: Acta crystallographica. Section E, Structure reports online 20080501
Title: A manganese(II) coordination polymer with mixed pyrimidine-2-carboxylate and oxalate bridges: synthesis, structure, and magnetism.
Journal: Dalton transactions (Cambridge, England : 2003) 20080421
Title: Bis(pyrimidine-2-carboxyl-ato-κN,O)copper(II).
Journal: Acta crystallographica. Section E, Structure reports online 20080101
Title: Pyrimidine-2-carboxamide.
Journal: Acta crystallographica. Section E, Structure reports online 20080101
Title: 1,2-Bis[amino-(pyrimidin-2-yl)methyl-ene]hydrazine dihydrate.
Journal: Acta crystallographica. Section E, Structure reports online 20080101
Title: Synthesis, X-ray structures and luminescence properties of three multidimensional metal-organic frameworks incorporating the versatile 5-(pyrimidyl)tetrazolato bridging ligand.
Journal: Dalton transactions (Cambridge, England : 2003) 20070514
Title: Self-assembled cationic heterochiral honeycomb-layered metal complexes with the in situ generated pyrimidine-2-carboxylato bisdidentate ligand. Hydrothermal synthesis, crystal structures, magnetic properties, and theoretical study of [M2(micro-pymca)3]OH.H2O (M = FeII, CoII).
Journal: Inorganic chemistry 20070402
Title: 5-Cyanopyrimidine derivatives as a novel class of potent, selective, and orally active inhibitors of p38alpha MAP kinase.
Journal: Journal of medicinal chemistry 20051006
Title: Altmann E, et al. 2-Cyano-pyrimidines: a new chemotype for inhibitors of the cysteine protease cathepsin K. J Med Chem. 2007 Feb 22;50(4):591-4.
