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141117-12-6,MFCD30738181
Catalog No.:AA00JNOO

141117-12-6 | Celgosivir hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
1 week  
$336.00   $235.00
- +
5mg
98%
1 week  
$717.00   $502.00
- +
10mg
98%
1 week  
$1,003.00   $702.00
- +
25mg
98%
1 week  
$1,543.00   $1,080.00
- +
50mg
98%
1 week  
$2,590.00   $1,813.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00JNOO
Chemical Name:
Celgosivir hydrochloride
CAS Number:
141117-12-6
Molecular Formula:
C12H22ClNO5
Molecular Weight:
295.7598
MDL Number:
MFCD30738181
SMILES:
CCCC(=O)O[C@H]1CN2CC[C@@H]([C@@H]2[C@H]([C@@H]1O)O)O.Cl
Properties
Computed Properties
 
Complexity:
311  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
4  

Literature

Title: Taylor DL, et al. Inhibition of alpha-glucosidase I of the glycoprotein-processing enzymes by 6-O-butanoylcastanospermine (MDL 28,574) and its consequences in human immunodeficiency virus-infected T cells. Antimicrob Agents Chemother. 1994 Aug;38(8):1780-7.

Title: Whitby K, et al. Action of celgosivir (6 O-butanoyl castanospermine) against the pestivirus BVDV: implications for the treatment of hepatitis C. Antivir Chem Chemother. 2004 May;15(3):141-51.

Title: Watanabe S, et al. Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial. Antiviral Res. 2012 Oct;96(1):32-5.

Title: Rathore AP, et al. Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes andprotects against lethal challenge mouse model. Antiviral Res. 2011 Dec;92(3):453-60.

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SDS
Tags:141117-12-6 Molecular Formula|141117-12-6 MDL|141117-12-6 SMILES|141117-12-6 Celgosivir hydrochloride