Home Amines 14116-06-4
14116-06-4,MFCD07780753
Catalog No.:AA001FXE

14116-06-4 | Benzeneethanamine, α-methyl-4-(methylthio)-

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  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001FXE
Chemical Name:
Benzeneethanamine, α-methyl-4-(methylthio)-
CAS Number:
14116-06-4
Molecular Formula:
C10H15NS
Molecular Weight:
181.2978
MDL Number:
MFCD07780753
SMILES:
CSc1ccc(cc1)CC(N)C
Properties
Computed Properties
 
Complexity:
119  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.3  

Literature

Title: An insight into the hepatocellular death induced by amphetamines, individually and in combination: the involvement of necrosis and apoptosis.

Journal: Archives of toxicology 20131201

Title: Identification of common impurities present in the synthetic routes leading to 4-methylthioamphetamine (4-MTA). Part II: Reductive amination and nitropropene route.

Journal: Forensic science international 20120410

Title: Identification and synthesis of by-products found in 4-methylthioamphetamine (4-MTA) produced by the Leuckart method.

Journal: Forensic science international 20120310

Title: Simultaneous detection of ten psychedelic phenethylamines in urine by gas chromatography-mass spectrometry.

Journal: Journal of analytical toxicology 20110901

Title: The synthesis, mass spectrometric properties and identification of some N,N-di-(β-arylisopropyl)formamides related to the synthesis of ring-modified amphetamines.

Journal: Forensic science international 20110320

Title: Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents.

Journal: Bioorganic & medicinal chemistry 20110201

Title: Legal highs: the dark side of medicinal chemistry.

Journal: Nature 20110106

Title: Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted alpha-alkylthioamphetamines.

Journal: Bioorganic & medicinal chemistry 20100601

Title: Comparative effects of 3,4-methylenedioxymethamphetamine and 4-methylthioamphetamine on rat liver mitochondrial function.

Journal: Toxicology 20100411

Title: Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents.

Journal: European journal of medicinal chemistry 20091201

Title: The analytical profile of some 4-methylthioamphetamine (4-MTA) homologues.

Journal: Forensic science international 20091120

Title: Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors.

Journal: Bioorganic & medicinal chemistry 20090315

Title: N,N-dimethyl-thioamphetamine and methyl-thioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents.

Journal: Journal of neurochemistry 20080601

Title: CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA).

Journal: Toxicology 20070118

Title: Blockade of noradrenaline transport abolishes 4-methylthioamphetamine-induced contraction of the rat aorta in vitro.

Journal: Autonomic & autacoid pharmacology 20061001

Title: Amphetamines as potential inducers of fatalities: a review in the district of Ghent from 1976-2004.

Journal: Medicine, science, and the law 20060101

Title: Studies on the metabolism and toxicological detection of the designer drug 4-methylthioamphetamine (4-MTA) in human urine using gas chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925

Title: Amphetamine toxicity in the emergency department.

Journal: European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20050801

Title: Metabolism of designer drugs of abuse.

Journal: Current drug metabolism 20050601

Title: Sulfur-substituted alpha-alkyl phenethylamines as selective and reversible MAO-A inhibitors: biological activities, CoMFA analysis, and active site modeling.

Journal: Journal of medicinal chemistry 20050407

Title: Identification of synthetic precursors of amphetamine-like drugs using Raman spectroscopy and ab initio calculations: beta-Methyl-beta-nitrostyrene derivatives.

Journal: The Analyst 20041101

Title: Simultaneous determination of amphetamine derivatives in human urine after SPE extraction and HPLC-UV analysis.

Journal: Biomedical chromatography : BMC 20040301

Title: Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040201

Title: 4-Methylthioamphetamine-induced hyperthermia in mice: influence of serotonergic and catecholaminergic pathways.

Journal: Toxicology and applied pharmacology 20030801

Title: Monoamine oxidase inhibitory properties of optical isomers and N-substituted derivatives of 4-methylthioamphetamine.

Journal: Journal of enzyme inhibition and medicinal chemistry 20030801

Title: Screening for and validated quantification of amphetamines and of amphetamine- and piperazine-derived designer drugs in human blood plasma by gas chromatography/mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20030601

Title: p-Methylthioamphetamine and 1-(m-chlorophenyl)piperazine, two non-neurotoxic 5-HT releasers in vivo, differ from neurotoxic amphetamine derivatives in their mode of action at 5-HT nerve endings in vitro.

Journal: Journal of neurochemistry 20020901

Title: 4-MTA: a new synthetic drug on the dance scene.

Journal: Drug and alcohol dependence 20020701

Title: In vitro neuronal and vascular responses to 5-hydroxytryptamine: modulation by 4-methylthioamphetamine, 4-methylthiomethamphetamine and 3,4-methylenedioxymethamphetamine.

Journal: European journal of pharmacology 20020524

Title: Identification of 4-methylthioamphetamine and some of its metabolites in mouse urine by GC-MS after acute administration.

Journal: Journal of analytical toxicology 20020101

Title: Analysis of 4-methylthioamphetamine in clinical specimens.

Journal: Annals of clinical biochemistry 20010701

Title: Synthesis of 4-methyl-5-arylpyrimidines and 4-arylpyrimidines: route specific markers for the Leuckardt preparation of amphetamine, 4-methoxyamphetamine, and 4-methylthioamphetamine.

Journal: Forensic science international 20010101

Title: One fatal and seven non-fatal cases of 4-methylthioamphetamine (4-MTA) intoxication: clinico-pathological findings.

Journal: International journal of legal medicine 20010101

Title: Fatal 4-MTA intoxication: development of a liquid chromatographic-tandem mass spectrometric assay for multiple matrices.

Journal: Journal of analytical toxicology 20010101

Title: WHO Expert Committee on Drug Dependence. Thirty-second report.

Journal: World Health Organization technical report series 20010101

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