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141396-28-3,MFCD00895735
Catalog No.:AA001G9N

141396-28-3 | Argatroban monohydrate

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1mg
98%
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$8.00   $6.00
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5mg
98%
in stock  
$19.00   $14.00
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25mg
98%
in stock  
$29.00   $21.00
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50mg
98%
in stock  
$37.00   $26.00
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250mg
98%
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$71.00   $50.00
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1g
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$207.00   $145.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001G9N
Chemical Name:
Argatroban monohydrate
CAS Number:
141396-28-3
Molecular Formula:
C23H38N6O6S
Molecular Weight:
526.6494
MDL Number:
MFCD00895735
SMILES:
NC(=N)NCCC[C@@H](C(=O)N1CC[C@H](C[C@@H]1C(=O)O)C)NS(=O)(=O)c1cccc2c1NCC(C2)C.O
Properties
Computed Properties
 
Complexity:
887  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
9  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Use of argatroban and catheter-directed thrombolysis with alteplase in an oncology patient with heparin-induced thrombocytopenia with thrombosis.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20140501

Title: Heparin-induced thrombocytopenia in essential thrombocytosis.

Journal: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20121101

Title: Bleeding risk factors associated with argatroban therapy in the critically ill.

Journal: Journal of thrombosis and thrombolysis 20121101

Title: Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome.

Journal: Expert opinion on drug metabolism & toxicology 20121101

Title: Treatment outcomes of heparin-induced thrombocytopenia in subarachnoid hemorrhage patients: a 4-year, retrospective single-center review.

Journal: Neurocritical care 20121001

Title: Therapeutic administration of the direct thrombin inhibitor argatroban reduces hepatic inflammation in mice with established fatty liver disease.

Journal: The American journal of pathology 20121001

Title: Measuring direct thrombin inhibitors with routine and dedicated coagulation assays: which assay is helpful?

Journal: American journal of clinical pathology 20121001

Title: Direct thrombin inhibitors for management of heparin-induced thrombocytopenia in patients receiving renal replacement therapy: comparison of clinical outcomes.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120915

Title: Translational success stories: development of direct thrombin inhibitors.

Journal: Circulation research 20120914

Title: Outcomes after heparin-induced thrombocytopenia in patients with Propaten vascular grafts.

Journal: Annals of vascular surgery 20120801

Title: Use of the chromogenic factor X assay in patients transitioning from argatroban to warfarin therapy.

Journal: Pharmacotherapy 20120601

Title: In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity.

Journal: Integrative biology : quantitative biosciences from nano to macro 20120601

Title: Alternative anticoagulation during cardiovascular procedures in pediatric patients with heparin-induced thrombocytopenia.

Journal: The journal of extra-corporeal technology 20120601

Title: Thrombin activity associated with neuronal damage during acute focal ischemia.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120530

Title: Thrombin inhibition profiles in healthy individuals and thrombophilic patients.

Journal: Thrombosis and haemostasis 20120501

Title: Recognition of heparin-induced thrombocytopenia and initiation of argatroban therapy after cardiothoracic surgery in the intensive care unit.

Journal: The Journal of thoracic and cardiovascular surgery 20120501

Title: Development of a fast and simple liquid chromatography-tandem mass spectrometry method for the quantitation of argatroban in patient plasma samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120415

Title: Results of a consensus meeting on the use of argatroban in patients with heparin-induced thrombocytopenia requiring antithrombotic therapy - a European Perspective.

Journal: Thrombosis research 20120401

Title: Argatroban therapy for heparin-induced thrombocytopenia during pregnancy in a woman with hereditary antithrombin deficiency.

Journal: The journal of obstetrics and gynaecology research 20120401

Title: [Anesthesia for a hemodialysis patient with HIT undergoing CABG using argatroban].

Journal: Masui. The Japanese journal of anesthesiology 20120401

Title: High-dose argatroban for treatment of heparin-induced thrombocytopenia with thrombosis: a case report and review of laboratory considerations.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120315

Title: The argatroban and tissue-type plasminogen activator stroke study: final results of a pilot safety study.

Journal: Stroke 20120301

Title: The argatroban and tissue-type plasminogen activator stroke study: final results of a pilot safety study.

Journal: Stroke 20120301

Title: Argatroban anticoagulation for heparin induced thrombocytopenia in patients with ventricular assist devices.

Journal: Minerva anestesiologica 20120301

Title: Development and implementation of a comprehensive heparin-induced thrombocytopenia recognition and management protocol.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120201

Title: Parenteral anticoagulants: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Journal: Chest 20120201

Title: Combined argatroban and anti-oxidative agents prevents increased vascular contractility to thrombin and other ligands after subarachnoid haemorrhage.

Journal: British journal of pharmacology 20120101

Title: Novel insights into the delayed vasospasm following subarachnoid haemorrhage: importance of proteinase signalling.

Journal: British journal of pharmacology 20120101

Title: A case of acute coronary artery occlusion associated with very rapid onset heparin-induced thrombosis without thrombocytopenia.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: Hitting back HIT.

Journal: Annals of cardiac anaesthesia 20120101

Title: Hemodialysis with a dialyzer loaded with argatroban may be performed in vivo without a systemic anticoagulant.

Journal: Blood purification 20120101

Title: Newer anticoagulants for the prevention of venous thromboembolism.

Journal: The National medical journal of India 20120101

Title: Old and new antithrombotic drugs in neonates and infants.

Journal: Seminars in fetal & neonatal medicine 20111201

Title: Identifying patient- and treatment-related factors related to amputation risk in cases of heparin-induced thrombocytopenia treated with argatroban.

Journal: International angiology : a journal of the International Union of Angiology 20111201

Title: Immobilization of anticoagulant-loaded liposomes on cell surfaces by DNA hybridization.

Journal: Biomaterials 20111101

Title: Water-soluble argatroban for antithrombogenic surface coating of tissue-engineered cardiovascular tissues.

Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20111101

Title: Systemic administration of argatroban inhibits protease-activated receptor-1 expression in perihematomal tissue in rats with intracerebral hemorrhage.

Journal: Brain research bulletin 20111010

Title: Monitoring of the anticoagulants argatroban and lepirudin: a comparison of laboratory methods.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20111001

Title: Direct thrombin inhibitors.

Journal: British journal of clinical pharmacology 20111001

Title: Effects of argatroban as an anticoagulant for intermittent veno-venous hemofiltration (IVVH) in patients at high risk of bleeding.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110901

Title: Heparin-induced thrombocytopenia type II because of heparin-coated polytetrafluoroethylene graft used to bypass.

Journal: Annals of vascular surgery 20110801

Title: Management of argatroban surrounding a lumbar puncture: a case report.

Journal: American journal of hematology 20110801

Title: Implementation of an individualized argatroban protocol in an academic medical center.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110715

Title: Argatroban therapy in pediatric patients requiring nonheparin anticoagulation: an open-label, safety, efficacy, and pharmacokinetic study.

Journal: Pediatric blood & cancer 20110701

Title: Long-term animal implantation study of biotube-autologous small-caliber vascular graft fabricated by in-body tissue architecture.

Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20110701

Title: Profiling of active thrombin in human blood by supramolecular complexes.

Journal: Angewandte Chemie (International ed. in English) 20110627

Title: Anticoagulation with argatroban for elective percutaneous coronary intervention: population pharmacokinetics and pharmacokinetic-pharmacodynamic relationship of coagulation parameters.

Journal: Journal of clinical pharmacology 20110601

Title: [Diagnosis and treatment of heparin-induced thrombocytopenia].

Journal: Deutsche medizinische Wochenschrift (1946) 20110501

Title: Argatroban for elective percutaneous coronary intervention: the ARG-E04 multi-center study.

Journal: International journal of cardiology 20110414

Title: Practical viewpoints on the diagnosis and management of heparin-induced thrombocytopenia.

Journal: Seminars in thrombosis and hemostasis 20110401

Title: [Interventional lung assist membrane ventilator. Successful use despite heparin-induced thrombocytopenia type II].

Journal: Der Anaesthesist 20110301

Title: Evaluation of empiric versus nomogram-based direct thrombin inhibitor management in patients with suspected heparin-induced thrombocytopenia.

Journal: American journal of hematology 20110301

Title: Use of argatroban as a procedural and bridging anticoagulant in a patient undergoing carotid endarterectomy with concomitant atrial fibrillation.

Journal: The Annals of pharmacotherapy 20110301

Title: Argatroban therapy using enzymatic anti-factor IIa monitoring.

Journal: The Annals of pharmacotherapy 20110301

Title: [Efficacy of regional administration of urokinase and argatroban via small saphenous vein catheter for treatment of acute deep venous thrombosis in the lower limb].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110301

Title: Venous limb gangrene and fatal hemorrhage: adverse consequences of HIT 'overdiagnosis' in a patient with antiphospholipid syndrome.

Journal: American journal of hematology 20110201

Title: Thrombosis prophylaxis in critically ill patients.

Journal: Wiener medizinische Wochenschrift (1946) 20110201

Title: Direct thrombin and factor Xa inhibitors in children: a quest for new anticoagulants for children.

Journal: Wiener medizinische Wochenschrift (1946) 20110201

Title: [Synthetic protease inhibitors for the treatment of DIC].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20110201

Title: Pharmacokinetic and pharmacodynamic basis for effective argatroban dosing in pediatrics.

Journal: Journal of clinical pharmacology 20110101

Title: A patient with 'spontaneous' heparin-induced thrombocytopenia and thrombosis after undergoing knee replacement.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20110101

Title: A randomized, open-label pilot study comparing desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis: PREVENT-HIT Study.

Journal: American journal of therapeutics 20110101

Title: Hypereosinophilic syndrome with cardiac involvement in a pregnant patient with multiple sclerosis.

Journal: Texas Heart Institute journal 20110101

Title: An optimized method to assess in vivo efficacy of antithrombotic drugs using optical coherence tomography and a modified Doppler flow system.

Journal: Journal of pharmacological and toxicological methods 20110101

Title: Argatroban 'reversal' is caused by nonphysiologic stimulation of coagulation, not activated factor VII.

Journal: Journal of cardiothoracic and vascular anesthesia 20101201

Title: Carbon monoxide releasing molecule-2 enhances coagulation and diminishes fibrinolytic vulnerability in plasma exposed to heparin or argatroban.

Journal: Anesthesia and analgesia 20101201

Title: Comparison of bivalirudin and argatroban for the management of heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20101201

Title: Extracorporeal membrane oxygenation bridging to lung transplant complicated by heparin-induced thrombocytopenia.

Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20101201

Title: Argatroban administration reduces leukocyte adhesion and improves capillary perfusion within the intestinal microcirculation in experimental sepsis.

Journal: Thrombosis and haemostasis 20101101

Title: [Concept of branch atheromatous disease (BAD) and its clinical significance].

Journal: Rinsho shinkeigaku = Clinical neurology 20101101

Title: Difficult management of anticoagulation with argatroban in a patient undergoing on-pump cardiac surgery.

Journal: Journal of cardiothoracic and vascular anesthesia 20101001

Title: Safety and efficacy of the argatroban therapy during the early post-cardiac surgery period.

Journal: Journal of thrombosis and thrombolysis 20101001

Title: Pharmacotherapy in the critically ill obese patient.

Journal: Critical care clinics 20101001

Title: Pharmacology of argatroban.

Journal: Expert review of hematology 20101001

Title: Low dose of argatroban saline flushes anticoagulation in hemodialysis patients with high risk of bleeding.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20100801

Title: Argatroban and renal replacement therapy in a morbidly obese patient with heparin-induced thrombocytopenia: a case report.

Journal: Thrombosis research 20100801

Title: Treatment with argatroban in one haemodialysed patient with a heparin-induced thrombocytopenia and thrombotic complications.

Journal: Internal and emergency medicine 20100801

Title: Serious acute coronary thrombosis associated with heparin-induced thrombocytopenia in off-pump coronary artery bypass grafting.

Journal: Interactive cardiovascular and thoracic surgery 20100801

Title: Apixaban, a direct factor Xa inhibitor, inhibits tissue-factor induced human platelet aggregation in vitro: comparison with direct inhibitors of factor VIIa, XIa and thrombin.

Journal: Thrombosis and haemostasis 20100801

Title: Fondaparinux therapy in a hemodialysis patient with heparin-induced thrombocytopenia type II.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100701

Title: [Heparin-induced thrombocytopenia after on-pump coronary artery bypass grafting].

Journal: Kyobu geka. The Japanese journal of thoracic surgery 20100601

Title: An overview of heparin-induced thrombocytopenia.

Journal: Journal of pharmacy practice 20100601

Title: The direct thrombin inhibitors (argatroban, bivalirudin and lepirudin) and the indirect Xa-inhibitor (danaparoid) increase fibrin network porosity and thus facilitate fibrinolysis.

Journal: Thrombosis and haemostasis 20100501

Title: Prolonged elevation of plasma argatroban in a cardiac transplant patient with a suspected history of heparin-induced thrombocytopenia with thrombosis.

Journal: Transfusion 20100401

Title: Argatroban as a substitute of heparin during cardiopulmonary bypass: a safe alternative?

Journal: Interactive cardiovascular and thoracic surgery 20100401

Title: The direct thrombin inhibitor argatroban effectively prevents cardiac catheter thrombosis in vitro.

Journal: Thrombosis and haemostasis 20100401

Title: Rationale and design of the PREVENT-HIT study: a randomized, open-label pilot study to compare desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis.

Journal: Clinical therapeutics 20100401

Title: Cooperative antithrombotic effect from the simultaneous inhibition of thrombin and factor Xa.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20100301

Title: Laboratory monitoring of new anticoagulants.

Journal: American journal of hematology 20100301

Title: Thrombolytic therapy and thrombectomy in phlegmasia cerulea dolens.

Journal: The journal of the Royal College of Physicians of Edinburgh 20100301

Title: Review: recent advances in argatroban-warfarin transition in patients with heparin-induced thrombocytopenia.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20100201

Title: Heparin-induced thrombocytopenia in two patients undergoing abdominal aortic aneurysm surgery.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20100201

Title: Inhibition of thrombin action ameliorates insulin resistance in type 2 diabetic db/db mice.

Journal: Endocrinology 20100201

Title: Heparin-induced thrombocytopenia and cardiac surgery.

Journal: Current opinion in anaesthesiology 20100201

Title: Simultaneous use of argatroban and heparin during cardiopulmonary bypass.

Journal: Asian cardiovascular & thoracic annals 20100201

Title: Impact of renal function on argatroban therapy during percutaneous coronary intervention.

Journal: Journal of thrombosis and thrombolysis 20100101

Title: Anticoagulation with argatroban in a parturient with heparin-induced thrombocytopenia.

Journal: International journal of obstetric anesthesia 20100101

Title: An evaluation of monitoring possibilities of argatroban using rotational thromboelastometry and activated partial thromboplastin time.

Journal: Acta anaesthesiologica Scandinavica 20100101

Title: Autologous small-caliber 'biotube' vascular grafts with argatroban loading: a histomorphological examination after implantation to rabbits.

Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20100101

Title: Quantitation of argatroban in plasma using liquid chromatography electrospray tandem mass spectrometry (UPLC-ESI-MS/MS).

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Argatroban therapy for heparin-induced thrombocytopenia in ICU patients with multiple organ dysfunction syndrome: a retrospective study.

Journal: Critical care (London, England) 20100101

Title: Argatroban in the management of heparin-induced thrombocytopenia.

Journal: Vascular health and risk management 20100101

Title: Thrombin inhibition in subarachnoid hemorrhage.

Journal: Neurosurgery 20091201

Title: [Heparin-induced thrombocytopenia type II with thrombosis in an intensive care patient: therapy management using the direct thrombin inhibitor argatroban].

Journal: Der Anaesthesist 20091101

Title: RapidTEG observation suggests activation of factor VII may overcome argatroban-induced coagulopathy.

Journal: Journal of cardiothoracic and vascular anesthesia 20091001

Title: Thrombin generation by intimal tissue factor contributes to thrombus formation on macrophage-rich neointima but not normal intima of hyperlipidemic rabbits.

Journal: Atherosclerosis 20091001

Title: Heparin-induced thrombocytopenia with multiple organized thrombi accompanied by unusual cholesterin deposition: autopsy case after long-term follow up.

Journal: Pathology international 20091001

Title: [Anticoagulation in critically ill patient].

Journal: Wiener medizinische Wochenschrift (1946) 20091001

Title: Argatroban dosage requirements and outcomes in intensive care versus non-intensive care patients.

Journal: Pharmacotherapy 20090901

Title: [Anesthetic management for a patient with heparin-induced thrombocytopenia (HIT) undergoing off-pump coronary bypass surgery using argatroban, a direct thrombin inhibitor].

Journal: Masui. The Japanese journal of anesthesiology 20090901

Title: A comparison of direct thrombin inhibitors in the treatment of Heparin-Induced Thrombocytopenia: a single institution experience.

Journal: Journal of thrombosis and thrombolysis 20090801

Title: Anticoagulation with the direct thrombin inhibitor argatroban in patients presenting with acute coronary syndromes.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090801

Title: HeartMate II implantation in patients with heparin-induced thrombocytopenia type II.

Journal: The Annals of thoracic surgery 20090801

Title: Clinical investigation in ACS and PCI: shooting in the dark at a moving target.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090801

Title: Anterior spinal artery as a collateral channel in patients with acute bilateral vertebral artery occlusions. Two case reports.

Journal: Neurologia medico-chirurgica 20090801

Title: Stabilization of the E* form turns thrombin into an anticoagulant.

Journal: The Journal of biological chemistry 20090724

Title: Dosing patterns and outcomes in African American, Asian, and Hispanic patients with heparin-induced thrombocytopenia treated with argatroban.

Journal: Journal of thrombosis and thrombolysis 20090701

Title: Influence of antithrombin and argatroban on disseminated intravascular coagulation parameters in a patient with septic shock.

Journal: Thrombosis research 20090701

Title: INR matters: a case on managing argatroban for bridging oral anticoagulation in a patient with heparin induced thrombocytopenia type II after mechanical heart valve replacement.

Journal: Thrombosis research 20090601

Title: Argatroban for anticoagulation in continuous renal replacement therapy.

Journal: Critical care medicine 20090601

Title: The effect of argatroban on activated protein C resistance.

Journal: American journal of clinical pathology 20090601

Title: Argatroban and bivalirudin compared to unfractionated heparin in preventing thrombus formation on mechanical heart valves. Results of an in-vitro study.

Journal: Thrombosis and haemostasis 20090601

Title: Heparin-induced thrombocytopenia. A contemporary clinical approach to diagnosis and management.

Journal: Chest 20090601

Title: [Clinical observation of heparin-induced thrombocytopenia].

Journal: Zhonghua yi xue za zhi 20090526

Title: Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats.

Journal: Stroke 20090401

Title: Argatroban and catheter-directed thrombolysis with alteplase for limb- and graft-threatening thromboses in a patient with a history of HIT.

Journal: American journal of hematology 20090401

Title: [A study of the dosage of argatroban for anticoagulation effect in the patients undergoing high volume hemofiltration].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20090401

Title: Comparison of activated clotting times obtained using Hemochron and Medtronic analysers in patients receiving anti-thrombin therapy during cardiac catheterisation.

Journal: Thrombosis and haemostasis 20090301

Title: A report of outcomes after orthotopic liver transplant with allografts from heparin antibody-positive donors.

Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20090301

Title: [Argatroban treatment of heparin-induced immune-mediated thrombocytopenia].

Journal: Ugeskrift for laeger 20090216

Title: [Heparin-induced thrombocytopenia].

Journal: Ugeskrift for laeger 20090216

Title: The effect of ex vivo anticoagulants on whole blood platelet aggregation.

Journal: Platelets 20090201

Title: 84-year-old woman with hemodialysis-associated shortness of breath.

Journal: Mayo Clinic proceedings 20090201

Title: Heparin-induced thrombocytopenia: what clinicians need to know.

Journal: Thrombosis and haemostasis 20090201

Title: [Use of argatroban during cardiopulmonary bypass for atrial septal defect with heparin induced thrombocytopenia after introduction of dialysis].

Journal: Kyobu geka. The Japanese journal of thoracic surgery 20090201

Title: Argatroban for anticoagulation in continuous renal replacement therapy.

Journal: Critical care medicine 20090101

Title: 'Drug dosing in the intensive care unit: the critically ill are a special population too'.

Journal: Critical care medicine 20090101

Title: Effects of critical illness and organ failure on therapeutic argatroban dosage requirements in patients with suspected or confirmed heparin-induced thrombocytopenia.

Journal: The Annals of pharmacotherapy 20090101

Title: Weight-based argatroban dosing nomogram for treatment of heparin-induced thrombocytopenia.

Journal: The Annals of pharmacotherapy 20090101

Title: Argatroban therapy in heparin-induced thrombocytopenia.

Journal: AACN advanced critical care 20090101

Title: Reducing harm associated with anticoagulation: practical considerations of argatroban therapy in heparin-induced thrombocytopenia.

Journal: Drug safety 20090101

Title: Use of argatroban during multi-organ procurement: pharmacokinetics and sequelae in recipient of transplanted liver.

Journal: Clinical transplantation 20090101

Title: Argatroban: a review of its use in the management of heparin-induced thrombocytopenia.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20090101

Title: Heparin-induced thrombocytopenia: when a low platelet count is a mandate for anticoagulation.

Journal: Hematology. American Society of Hematology. Education Program 20090101

Title: Argatroban enhances fibrinolysis by differential inhibition of thrombin-mediated activation of thrombin activatable fibrinolysis inhibitor and factor XIII.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20081201

Title: Successful use of argatroban during the third trimester of pregnancy: case report and review of the literature.

Journal: Pharmacotherapy 20081201

Title: Risk factors for major bleeding in patients with heparin-induced thrombocytopenia treated with argatroban: a retrospective study.

Journal: Journal of cardiovascular pharmacology 20081201

Title: Management of anticoagulation in patients with subacute heparin-induced thrombocytopenia scheduled for heart transplantation.

Journal: Blood 20081115

Title: Heparin-induced thrombocytopenia (HIT) causing pulmonary emboli during coronary intervention.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081115

Title: The thrombin inhibitor Argatroban reduces breast cancer malignancy and metastasis via osteopontin-dependent and osteopontin-independent mechanisms.

Journal: Breast cancer research and treatment 20081101

Title: Thrombin enhances the production of monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 in cultured rat glomerular epithelial cells.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081101

Title: Use of Argatroban for anticoagulation during cardiopulmonary bypass in a patient with heparin allergy.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20081101

Title: Management of uremic patients with heparin-induced thrombocytopenia requiring hemodialysis.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20081001

Title: Complete salvage of impending free flap failure in heparin induced thrombocytopenia by emergent institution of therapy with argatroban.

Journal: Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20081001

Title: Rivaroxaban--an oral, direct Factor Xa inhibitor--has potential for the management of patients with heparin-induced thrombocytopenia.

Journal: British journal of haematology 20081001

Title: [Three cases of small brain infarction in the lateral wall of the fourth ventricle presenting with paroxysmal positional vertigo and vomiting].

Journal: Rinsho shinkeigaku = Clinical neurology 20081001

Title: Inhibition of osteopontin dependent carcinogenesis.

Journal: Journal of cancer research and clinical oncology 20080801

Title: Argatroban use in heparin-induced thrombocytopenia.

Journal: Expert opinion on pharmacotherapy 20080801

Title: Therapeutic effect of argatroban on rheumatoid vasculitis with antiphosphatidylserine-prothrombin complex antibody.

Journal: Archives of dermatology 20080801

Title: Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th edition). Addendum.

Journal: Chest 20080801

Title: Influence of continuous veno-venous hemofiltration on argatroban clearance in a patient with septic shock.

Journal: Intensive care medicine 20080701

Title: Efficacy and safety of argatroban in patients with heparin induced thrombocytopenia undergoing endovascular intervention for peripheral arterial disease.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080701

Title: Transition from argatroban to oral anticoagulation with phenprocoumon or acenocoumarol: effect on coagulation factor testing.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20080701

Title: What is the optimal anticoagulation level with argatroban during percutaneous coronary intervention?

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20080701

Title: Interaction between thrombin mutant W215A/E217A and direct thrombin inhibitor.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20080701

Title: Effect of body mass index on Argatroban therapy during percutaneous coronary intervention.

Journal: Journal of thrombosis and thrombolysis 20080601

Title: Influence of direct thrombin inhibitor argatroban on coagulation assays in healthy individuals, patients under oral anticoagulation therapy and patients with liver dysfunction.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20080601

Title: Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

Journal: Chest 20080601

Title: Argatroban in short-term percutaneous ventricular assist subsequent to heparin-induced thrombocytopenia.

Journal: The journal of extra-corporeal technology 20080601

Title: Heparins, low-molecular-weight heparins, and pentasaccharides: use in the older patient.

Journal: Cardiology clinics 20080501

Title: New anticoagulant agents: direct thrombin inhibitors.

Journal: Cardiology clinics 20080501

Title: Argatroban as a primary or secondary postoperative anticoagulant in patients implanted with ventricular assist devices.

Journal: The Annals of thoracic surgery 20080501

Title: Argatroban as a primary or secondary postoperative anticoagulant in patients implanted with ventricular assist devices. Invited commentary.

Journal: The Annals of thoracic surgery 20080501

Title: Heparin-induced thrombocytopenia: a review of current pharmacologic treatment.

Journal: Connecticut medicine 20080501

Title: Efficacy and safety of argatroban with or without glycoprotein IIb/IIIa inhibitor in patients with heparin induced thrombocytopenia undergoing percutaneous coronary intervention for acute coronary syndrome.

Journal: Journal of thrombosis and thrombolysis 20080401

Title: Argatroban therapy in patients with hepatic and renal impairment.

Journal: European journal of anaesthesiology 20080401

Title: [Heparin induced thrombocytopenia and anticoagulation in renal replacemant therapy].

Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20080401

Title: Prolonged half-life of argatroban in patients with renal dysfunction and antiphospholipid antibody syndrome being treated for heparin-induced thrombocytopenia.

Journal: American journal of hematology 20080301

Title: Reduced argatroban doses after coronary artery bypass graft surgery.

Journal: The Annals of pharmacotherapy 20080301

Title: Considerations for drug dosing post coronary artery bypass graft surgery.

Journal: The Annals of pharmacotherapy 20080301

Title: Standardizing the management of heparin-induced thrombocytopenia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080215

Title: The laboratory diagnosis and clinical management of patients with heparin-induced thrombocytopenia: an update.

Journal: Seminars in thrombosis and hemostasis 20080201

Title: Argatroban therapy in patients with coronary artery disease and heparin-induced thrombocytopenia.

Journal: Cardiology 20080101

Title: Visual evaluation of blood coagulation during mural thrombogenesis under high shear blood flow.

Journal: Thrombosis research 20080101

Title: Complete 1H and 13C assignments of (21R) and (21S) diastereomers of argatroban.

Journal: Magnetic resonance in chemistry : MRC 20080101

Title: Heparin-induced thrombocytopenia complicating hemodialysis.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20080101

Title: Thrombelastography in a patient with heparin-induced thrombocytopenia treated with argatroban.

Journal: Anesthesia and analgesia 20080101

Title: [Patient with heparin-induced thrombocytopenia type II and implanted left ventricular assist device].

Journal: Der Anaesthesist 20080101

Title: Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT)--bridging the River Coumarin.

Journal: Thrombosis and haemostasis 20080101

Title: Ultrasound-guided supraclavicular block in a patient anticoagulated with argatroban.

Journal: Pain practice : the official journal of World Institute of Pain 20080101

Title: Comparison of the ecarin chromogenic assay and different aPTT assays for the measurement of argatroban concentrations in plasma from healthy individuals and from coagulation factor deficient patients.

Journal: Thrombosis research 20080101

Title: Prediction of the therapeutic index of marketed anti-coagulants and anti-platelet agents by guinea pig models of thrombosis and hemostasis.

Journal: Thrombosis research 20080101

Title: Argatroban anticoagulation in renal dysfunction: a literature analysis.

Journal: Nephron. Clinical practice 20080101

Title: Argatroban anticoagulation in intensive care patients: effects of heart failure and multiple organ system failure.

Journal: Journal of intensive care medicine 20080101

Title: Argatroban anticoagulation for cardiac surgery with cardiopulmonary bypass in an infant with double outlet right ventricle and a history of heparin-induced thrombocytopenia.

Journal: Congenital heart disease 20080101

Title: Treatment of intracardiac thrombi with argatroban.

Journal: Acute cardiac care 20080101

Title: Management of a pediatric patient on the Berlin Heart Excor ventricular assist device with argatroban after heparin-induced thrombocytopenia.

Journal: ASAIO journal (American Society for Artificial Internal Organs : 1992) 20080101

Title: The use of alternative anti-coagulation strategies for a nocturnal home hemodialysis patient with heparin-induced thrombocytopenia.

Journal: CANNT journal = Journal ACITN 20080101

Title: Thrombin enhances glioma growth.

Journal: Acta neurochirurgica. Supplement 20080101

Title: Inhibition of thrombin generation in recalcified plasma.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20071201

Title: Catheter-directed thrombolysis of acute lower extremity arterial thrombosis in a patient with heparin-induced thrombocytopenia.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071201

Title: [Are new anticoagulants better?].

Journal: Investigacion clinica 20071201

Title: Development of self-expandable covered stents.

Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20071101

Title: Seizures, headache and thrombocytopenia: diagnosis and treatment do not always come in a standard sequence.

Journal: Internal and emergency medicine 20071001

Title: Argatroban therapy for heparin-induced thrombocytopenia in acutely ill patients.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20071001

Title: [Heparin-induced thrombocytopenia].

Journal: Revista espanola de cardiologia 20071001

Title: A case of heparin-induced thrombocytopenia with repeated episodes of acute lower extremity arterial thromboembolism during a short time.

Journal: Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 20071001

Title: Influence of argatroban on coagulation parameters in heparin-induced thrombocytopenia patients after cardiothoracic surgery.

Journal: Journal of thrombosis and haemostasis : JTH 20070901

Title: Heparin induced thrombocytopenia: diagnosis and management update.

Journal: Postgraduate medical journal 20070901

Title: Percutaneous coronary interventions in patients with heparin-induced thrombocytopenia.

Journal: Current cardiology reports 20070901

Title: Heparin induced thrombocytopenia: pathogenetic, clinical, diagnostic and therapeutic aspects.

Journal: Cardiovascular & hematological disorders drug targets 20070901

Title: Argatroban anticoagulation in obese versus nonobese patients: implications for treating heparin-induced thrombocytopenia.

Journal: Journal of clinical pharmacology 20070801

Title: Heparin-induced thrombocytopenia II-induced critical limb ischaemia treated with urokinase and argatroban.

Journal: Thrombosis and haemostasis 20070801

Title: Involvement of thrombin and mitogen-activated protein kinase pathways in hemorrhagic brain injury.

Journal: Experimental neurology 20070701

Title: Argatroban in extracorporeal membrane oxygenation.

Journal: Artificial organs 20070601

Title: Efficacy of anti-coagulant treatment with argatroban on cardioembolic stroke.

Journal: Journal of neurology 20070501

Title: Argatroban anticoagulation in critically ill patients.

Journal: The Annals of pharmacotherapy 20070501

Title: Argatroban anticoagulation for renal replacement therapy in patients with heparin-induced thrombocytopenia after cardiovascular surgery.

Journal: The Journal of thoracic and cardiovascular surgery 20070501

Title: Heparin-induced thrombocytopenia and thrombosis.

Journal: American journal of orthopedics (Belle Mead, N.J.) 20070501

Title: Assessing nonlinearity in compartment models via the relative curvature measure.

Journal: Journal of pharmacokinetics and pharmacodynamics 20070401

Title: Heparin-induced thrombocytopenia in intensive care patients.

Journal: Critical care medicine 20070401

Title: Heparin-induced thrombocytopenia: treatment options and special considerations.

Journal: Pharmacotherapy 20070401

Title: Impact of smart infusion technology on administration of anticoagulants (unfractionated Heparin, Argatroban, Lepirudin, and Bivalirudin).

Journal: The American journal of cardiology 20070401

Title: Essentials of anticoagulation in hemodialysis.

Journal: Hemodialysis international. International Symposium on Home Hemodialysis 20070401

Title: Argatroban for anticoagulation in pediatric patients with heparin-induced thrombocytopenia requiring extracorporeal life support.

Journal: Journal of pediatric hematology/oncology 20070401

Title: Differential effects of direct thrombin inhibitors and antithrombin-dependent anticoagulants on the dynamics of clot formation.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070301

Title: Platelet activity, coagulation, and fibrinolysis during exercise in healthy males: effects of thrombin inhibition by argatroban and enoxaparin.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20070201

Title: [Two surgical case reports showing atypical heparin-induced thrombocytopenia].

Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20070201

Title: Alternative anticoagulation management strategies for the patient with heparin-induced thrombocytopenia undergoing cardiac surgery.

Journal: Journal of cardiothoracic and vascular anesthesia 20070201

Title: [Bilateral cerebellar infarction caused by intracranial dissection of the vertebral artery after long periods of 'Shiatsu'].

Journal: No to shinkei = Brain and nerve 20070201

Title: Argatroban for anticoagulation during cardiac surgery.

Journal: European journal of haematology 20070201

Title: Hydroxyethyl starch enhances argatroban-mediated decreases in clot propagation and strength by diminishing thrombin-fibrinogen interactions.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070101

Title: Direct thrombin inhibition during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia.

Journal: Expert review of cardiovascular therapy 20070101

Title: Anticoagulation options for patients with heparin-induced thrombocytopenia requiring renal support in the intensive care unit.

Journal: Contributions to nephrology 20070101

Title: Argatroban anticoagulation for heparin-induced thrombocytopenia in elderly patients.

Journal: Drugs & aging 20070101

Title: Heparin-induced thrombocytopenia: a general review.

Journal: Journal of infusion nursing : the official publication of the Infusion Nurses Society 20070101

Title: A case series describing the use of argatroban in patients on extracorporeal circulation.

Journal: ASAIO journal (American Society for Artificial Internal Organs : 1992) 20070101

Title: Argatroban therapy in women with heparin-induced thrombocytopenia.

Journal: Journal of women's health (2002) 20070101

Title: Anticoagulation for acute coronary syndromes: from heparin to direct thrombin inhibitors.

Journal: Reviews in cardiovascular medicine 20070101

Title: Direct thrombin inhibitors: alternatives to heparin.

Journal: Vascular 20070101

Title: Heparin-induced thrombocytopenia in the critical care setting: diagnosis and management.

Journal: Critical care medicine 20061201

Title: Effect of renal function on argatroban therapy in heparin-induced thrombocytopenia.

Journal: Journal of thrombosis and thrombolysis 20061201

Title: Heparin-induced thrombocytopenia: advances in diagnosis and treatment.

Journal: Critical care nurse 20061201

Title: Prolonged anticoagulation after discontinuation of argatroban and warfarin therapy in an obese patient with heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20061201

Title: Heparin-induced thrombocytopenia without thrombosis: an evidence-based review of current literature.

Journal: Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20061201

Title: [Argatroban].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20061028

Title: Anticoagulation strategies for treatment of ischemic stroke and antiphospholipid syndrome: case report and review of the literature.

Journal: Pharmacotherapy 20061001

Title: Systemic anticoagulation with argatroban during arteriovenous dialysis graft thrombolysis.

Journal: Journal of vascular and interventional radiology : JVIR 20061001

Title: Flavonoids inhibit the amidolytic activity of human thrombin.

Journal: Biochimie 20060901

Title: Anticoagulation with argatroban in patients with heparin-induced thrombocytopenia antibodies after cardiovascular surgery with cardiopulmonary bypass: first results from the ARG-E03 trial.

Journal: The Journal of thoracic and cardiovascular surgery 20060901

Title: Argatroban tPA stroke study: study design and results in the first treated cohort.

Journal: Archives of neurology 20060801

Title: [Two cases of heparin-induced thrombocytopenia (HIT) and a review of the literature].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20060801

Title: On-chip titration of an anticoagulant argatroban and determination of the clotting time within whole blood or plasma using a plug-based microfluidic system.

Journal: Analytical chemistry 20060715

Title: Heparin-induced thrombocytopenia and cardiovascular diseases.

Journal: American heart journal 20060701

Title: Argatroban, bivalirudin, and lepirudin do not decrease clot propagation and strength as effectively as heparin-activated antithrombin in vitro.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060601

Title: Recognition and management of heparin-induced thrombocytopenia in pediatric cardiopulmonary bypass patients.

Journal: The Annals of thoracic surgery 20060601

Title: Thrombotic end point for assessing argatroban therapy for heparin-induced thrombocytopenia: learning from secondary analyses of prospective studies.

Journal: Chest 20060601

Title: Effects of argatroban therapy, demographic variables, and platelet count on thrombotic risks in heparin-induced thrombocytopenia.

Journal: Chest 20060601

Title: Argatroban: update.

Journal: American heart journal 20060601

Title: [Pharmacotherapy: argatroban--alternative to heparin in case of heparin-induced thrombocytopenia type II (HIT II)].

Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20060601

Title: [Advanced medical therapy in patients with acute ischemic stroke].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060601

Title: Heparin-induced thrombocytopenia in a pediatric patient receiving extracorporeal support and treated with argatroban.

Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20060501

Title: Argatroban dosing of patients with heparin-induced thrombocytopenia and an elevated aPTT due to antiphospholipid antibody syndrome.

Journal: The Annals of pharmacotherapy 20060501

Title: Argatroban therapy in heparin-induced thrombocytopenia with hepatic dysfunction.

Journal: Chest 20060501

Title: Thrombin-induced delayed injury involves multiple and distinct signaling pathways in the cerebral cortex and the striatum in organotypic slice cultures.

Journal: Neurobiology of disease 20060401

Title: [Argatroban: pharmacological properties and anaesthesiological aspects].

Journal: Der Anaesthesist 20060401

Title: Evaluation of treatment with direct thrombin inhibitors in patients with heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20060401

Title: Inhibitors of blood coagulation factors Xa and IIa synergize to reduce thrombus weight and thrombin generation in vivo and in vitro.

Journal: Journal of thrombosis and haemostasis : JTH 20060401

Title: Argatroban: a direct thrombin inhibitor with reliable and predictable anticoagulant actions.

Journal: Drugs of today (Barcelona, Spain : 1998) 20060401

Title: Cardiac surgery in a patient with heparin-induced thrombocytopenia--cautions with use of the direct thrombin inhibitor, argatroban.

Journal: Connecticut medicine 20060401

Title: [Argatroban].

Journal: Deutsche medizinische Wochenschrift (1946) 20060331

Title: Safety and efficacy of argatroban in patients with heparin-induced thrombocytopenia.

Journal: Current hematology reports 20060301

Title: A new method for assessment of an anti-5HT(2A) agent, sarpogrelate hydrochloride, on platelet aggregation.

Journal: Journal of thrombosis and haemostasis : JTH 20060201

Title: Treatment of heparin-induced thrombocytopenia in cardiovascular patients.

Journal: Expert opinion on pharmacotherapy 20060201

Title: Successful recovery after an overdose of argatroban.

Journal: The Annals of pharmacotherapy 20060201

Title: [A case of heparin-induced thrombocytopenia associated with unexpected excessive argatroban anticoagulation after abdominal aortic aneurysm resection].

Journal: Masui. The Japanese journal of anesthesiology 20060201

Title: Antithrombin reduces reperfusion-induced hepatic metastasis of colon cancer cells.

Journal: World journal of gastroenterology 20060107

Title: Argatroban, a direct thrombin inhibitor for heparin-induced thrombocytopaenia: present and future perspectives.

Journal: Expert opinion on pharmacotherapy 20060101

Title: The cost-effectiveness of argatroban treatment in heparin-induced thrombocytopenia: the effect of early versus delayed treatment.

Journal: Cardiology in review 20060101

Title: Argatroban anticoagulation in pediatric patients: a literature analysis.

Journal: Journal of pediatric hematology/oncology 20060101

Title: Heparin-induced thrombocytopenia and cardiovascular patients: recognition and treatment.

Journal: Progress in cardiovascular nursing 20060101

Title: Argatroban for suspected heparin-induced thrombocytopenia: contemporary experience at a large teaching hospital.

Journal: Journal of intensive care medicine 20060101

Title: Heparin-induced thrombocytopenia in patients administered heparin solely for hemodialysis.

Journal: Renal failure 20060101

Title: Treatment of heparin-induced thrombocytopenia: a practical argatroban dosing protocol for nurses.

Journal: Journal of infusion nursing : the official publication of the Infusion Nurses Society 20060101

Title: Evaluation of diagnostic tests and argatroban or lepirudin therapy in patients with suspected heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20051201

Title: Heparin-induced thrombocytopenia from venous thromboembolism treatment.

Journal: Journal of internal medicine 20051201

Title: Comment: extensive prolongation of aPTT with argatroban in an elderly patient with improving renal function, normal hepatic enzymes, and metastatic lung cancer.

Journal: The Annals of pharmacotherapy 20051101

Title: Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation.

Journal: Thrombosis and haemostasis 20051101

Title: Mechanism of antithrombotic effect of heparin and antithrombin in balloon-injured arteries.

Journal: Life sciences 20051007

Title: Argatroban-coupled Affi-Gel matrix for the purification of thrombin from plasma.

Journal: Biotechnology and applied biochemistry 20051001

Title: Argatroban anticoagulation in patients with heparin-induced thrombocytopenia requiring renal replacement therapy.

Journal: The Annals of pharmacotherapy 20051001

Title: Presence of direct thrombin inhibitors can affect the results and interpretation of lupus anticoagulant testing.

Journal: American journal of clinical pathology 20051001

Title: Argatroban and lepirudin requirements in a 6-year-old patient with heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20051001

Title: Argatroban and lepirudin: clinical trials to clinical practice.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20051001

Title: A comparison of lepirudin and argatroban outcomes.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20051001

Title: [A case of anterior cerebral artery dissection causing enlargement of infarction].

Journal: Rinsho shinkeigaku = Clinical neurology 20051001

Title: Direct thrombin inhibitors.

Journal: The New England journal of medicine 20050908

Title: The role of thrombin in gliomas.

Journal: Journal of thrombosis and haemostasis : JTH 20050901

Title: Collaborative study on monitoring methods to determine direct thrombin inhibitors lepirudin and argatroban.

Journal: Journal of thrombosis and haemostasis : JTH 20050901

Title: Acute subdural hematoma: new model delineation and effects of coagulation inhibitors.

Journal: Neurosurgery 20050901

Title: Heparin and other rapidly acting anticoagulants.

Journal: Seminars in vascular surgery 20050901

Title: Cardiopulmonary bypass using argatroban as an anticoagulant for a 6.0-kg pediatric patient.

Journal: The journal of extra-corporeal technology 20050901

Title: Successful therapy with argatroban for superior mesenteric vein thrombosis in a patient with congenital antithrombin deficiency.

Journal: European journal of haematology 20050801

Title: Scanning electron microscopical observations of two novel hemostatic polymers.

Journal: Journal of thrombosis and haemostasis : JTH 20050701

Title: Thrombin inhibitor reduces leukocyte-endothelial cell interactions and vascular leakage after scatter laser photocoagulation.

Journal: Investigative ophthalmology & visual science 20050701

Title: Toxicity of argatroban overdose in a 65-year-old man.

Journal: American journal of hematology 20050701

Title: Transitioning from argatroban to warfarin therapy in patients with heparin-induced thrombocytopenia.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20050701

Title: [Heparin-induced thrombocytopenia (HIT): pathogenesis, laboratory test, and treatment].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20050701

Title: Evolving management strategies for heparin-induced thrombocytopenia.

Journal: Seminars in hematology 20050701

Title: Effect of argatroban on the activated partial thromboplastin time: a comparison of 21 commercial reagents.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20050601

Title: Extensive prolongation of aPTT with argatroban in an elderly patient with improving renal function, normal hepatic enzymes, and metastatic lung cancer.

Journal: The Annals of pharmacotherapy 20050601

Title: Direct thrombin inhibitors: pharmacology and clinical relevance.

Journal: Anaesthesia 20050601

Title: [Nontraumatic arterial dissection of the anterior cerebral artery: six cases report].

Journal: No to shinkei = Brain and nerve 20050601

Title: Transitioning from argatroban to warfarin in heparin-induced thrombocytopenia: an analysis of outcomes in patients with elevated international normalized ratio (INR).

Journal: Journal of thrombosis and thrombolysis 20050601

Title: The paradox of heparin-induced thrombocytopenia: the initial management.

Journal: Orthopedics 20050601

Title: Carotid tissue levels of argatroban after direct local delivery during carotid endarterectomy to prevent perioperative cerebral embolism.

Journal: Neurosurgery 20050501

Title: No increase in rejection or graft loss in kidney transplant recipients with thrombophilia treated with anticoagulation and triple immunosuppression.

Journal: Transplantation proceedings 20050501

Title: The use of argatroban for carotid endarterectomy in heparin-induced thrombocytopenia.

Journal: Anesthesia and analgesia 20050401

Title: Argatroban for anticoagulation during cardiopulmonary bypass in an infant.

Journal: Paediatric anaesthesia 20050401

Title: An anesthesia provider's perspective of heparin-induced thrombocytopenia.

Journal: AANA journal 20050401

Title: Heparin-induced thrombocytopenia: principles for early recognition and management.

Journal: Cleveland Clinic journal of medicine 20050401

Title: Antithrombotic potential of new direct thrombin inhibitors built on the azaphenylalanine scaffold in two rat venous thrombosis models.

Journal: Thrombosis and haemostasis 20050301

Title: Coagulation management of a patient with factor V Leiden mutation, lupus anticoagulant, and activated protein C resistance: a case report.

Journal: Perfusion 20050301

Title: Argatroban and renal replacement therapy in patients with heparin-induced thrombocytopenia.

Journal: The Annals of pharmacotherapy 20050201

Title: Transition to an oral anticoagulant in patients with heparin-induced thrombocytopenia.

Journal: Chest 20050201

Title: Direct thrombin inhibitors in heparin-induced thrombocytopenia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050201

Title: Use of the chromogenic factor X assay to predict the international normalized ratio in patients transitioning from argatroban to warfarin.

Journal: Pharmacotherapy 20050201

Title: Treatment of patients with a history of heparin-induced thrombocytopenia and anti-lepirudin antibodies with argatroban.

Journal: Journal of thrombosis and thrombolysis 20050201

Title: Spontaneous atrioventricular groove disruption during off-pump coronary artery bypass grafting.

Journal: The Annals of thoracic surgery 20050101

Title: Heparin-induced thrombocytopenia in the cardiovascular patient: diagnostic and treatment guidelines.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20050101

Title: Thrombin, an ideal target for pharmacological inhibition: a review of direct thrombin inhibitors.

Journal: American heart journal 20050101

Title: Thrombin-directed inhibitors: pharmacology and clinical use.

Journal: American heart journal 20050101

Title: Systemic administration of argatroban reduces secondary brain damage in a rat model of intracerebral hemorrhage: histopathological assessment.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20050101

Title: Argatroban treatment for patients with intolerance to heparin and hirudin.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20050101

Title: Alternative parenteral anticoagulation with argatroban, a direct thrombin inhibitor.

Journal: Expert review of cardiovascular therapy 20050101

Title: Selective methodologies for the synthesis of biologically active piperidinic compounds.

Journal: Chemical record (New York, N.Y.) 20050101

Title: Heparin-induced thrombocytopenia.

Journal: Disease-a-month : DM 20050101

Title: Argatroban anticoagulation in patients with a history of heparin-induced thrombocytopenia.

Journal: Thrombosis research 20050101

Title: Clinical presentation and laboratory diagnosis of heparin-induced thrombocytopenia.

Journal: Seminars in thoracic and cardiovascular surgery 20050101

Title: Anticoagulant use in patients with chronic renal impairment.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101

Title: Direct thrombin inhibitors are not equally effective in vivo against arterial thrombosis: in vivo evaluation of DuP714 and argatroban in a porcine angioplasty model and comparison to r-hirudin.

Journal: Thrombosis research 20050101

Title: New trends in anticoagulant treatments.

Journal: Lupus 20050101

Title: Thrombocytopenia following heparin flush.

Journal: Progress in cardiovascular nursing 20050101

Title: Inhibition of thrombin-induced vascular endothelial growth factor production in human neuroblastoma (NB-1) cells by argatroban.

Journal: Pathophysiology of haemostasis and thrombosis 20050101

Title: Systemic use of argatroban reduces tumor mass, attenuates neurological deficits and prolongs survival time in rat glioma models.

Journal: Acta neurochirurgica. Supplement 20050101

Title: Severe argatroban-induced coagulopathy in a patient with a history of heparin-induced thrombocytopenia.

Journal: The Annals of thoracic surgery 20041201

Title: Argatroban as a heparin substitute in cases of heparin-induced thrombocytopenia.

Journal: The Annals of thoracic surgery 20041201

Title: A prospective comparison of three argatroban treatment regimens during hemodialysis in end-stage renal disease.

Journal: Kidney international 20041201

Title: Current role of antithrombotic agents in the treatment of acute coronary syndromes.

Journal: Seminars in thrombosis and hemostasis 20041201

Title: Compatibility of argatroban with selected cardiovascular agents.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20041115

Title: [Clinical guidelines for stroke].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20041110

Title: Heparin-induced thrombocytopenia: diagnosis and management.

Journal: Circulation 20041102

Title: The effects of argatroban on thrombin generation and hemostatic activation in vitro.

Journal: Anesthesia and analgesia 20041101

Title: Effects of pentasaccharide (fondaparinux) and direct thrombin inhibitors on coagulation testing.

Journal: Archives of pathology & laboratory medicine 20041001

Title: Monitoring direct thrombin inhibitors: time for standardization.

Journal: Anesthesiology 20041001

Title: Comparing direct thrombin inhibitors using aPTT, ecarin clotting times, and thrombin inhibitor management testing.

Journal: The Annals of pharmacotherapy 20040901

Title: Pharmacokinetics and pharmacodynamics of argatroban in combination with a platelet glycoprotein IIB/IIIA receptor antagonist in patients undergoing percutaneous coronary intervention.

Journal: Journal of clinical pharmacology 20040901

Title: [Use of argatroban as a substitute for heparin in a patient with suspected HIT type II undergoing carotid endarterectomy].

Journal: Masui. The Japanese journal of anesthesiology 20040901

Title: [Prospective randomized study of argatroban versus heparin anticoagulation therapy after percutaneous coronary intervention for acute myocardial infarction].

Journal: Journal of cardiology 20040801

Title: Argatroban anticoagulation in conjunction with glycoprotein IIb/IIIa inhibition in patients undergoing percutaneous coronary intervention: an open-label, nonrandomized pilot study.

Journal: Journal of thrombosis and thrombolysis 20040801

Title: [Prevention and treatment of deep vein thrombosis with ximelagatran].

Journal: Deutsche medizinische Wochenschrift (1946) 20040723

Title: Ability of anti-glycoprotein IIb/IIIa agents to dissolve platelet thrombi formed on a collagen surface under blood flow conditions.

Journal: Journal of the American College of Cardiology 20040721

Title: Argatroban anticoagulation in patients with acute ischemic stroke (ARGIS-1): a randomized, placebo-controlled safety study.

Journal: Stroke 20040701

Title: Intraoperative management of a congenital antithrombin deficient patient on chronic hemodialysis.

Journal: Thrombosis and haemostasis 20040701

Title: Local delivery of argatroban for the prevention of restenosis after coronary balloon angioplasty: a prospective randomized pilot study.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20040701

Title: Heparin-induced thrombocytopenia and thrombosis in a patient with polycythemia vera.

Journal: Internal medicine (Tokyo, Japan) 20040701

Title: Transition from argatroban to oral anticoagulation with phenprocoumon or acenocoumarol: effects on prothrombin time, activated partial thromboplastin time, and Ecarin Clotting Time.

Journal: Thrombosis and haemostasis 20040601

Title: Collagen-induced generation of platelet-derived microparticles in whole blood is dependent on ADP released from red blood cells and calcium ions.

Journal: Platelets 20040601

Title: [Heparin-induced thrombocytopenia in patients on hemodialysis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040601

Title: Direct thrombin inhibitors in the treatment of immune-mediated heparin-induced thrombocytopenia.

Journal: Seminars in thrombosis and hemostasis 20040601

Title: Percutaneous interventions in patients with immune-mediated heparin-induced thrombocytopenia.

Journal: Seminars in thrombosis and hemostasis 20040601

Title: Argatroban usage for anticoagulation for ECMO on a post-cardiac patient with heparin-induced thrombocytopenia.

Journal: The journal of extra-corporeal technology 20040601

Title: Heparinless cardiopulmonary bypass with argatroban in dogs.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20040501

Title: Argatroban therapy for antithrombin deficiency and mesenteric thrombosis: case report and review of the literature.

Journal: Pharmacotherapy 20040501

Title: [How to use anticoagulants in hemodialysis therapy].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040501

Title: [Anticoagulant].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040501

Title: Stroke in patients with heparin-induced thrombocytopenia and the effect of argatroban therapy.

Journal: Critical care medicine 20040401

Title: Effect of direct thrombin inhibitors, bivalirudin, lepirudin, and argatroban, on prothrombin time and INR values.

Journal: American journal of clinical pathology 20040401

Title: Synthetic selective inhibitors of coagulation factor Xa strongly inhibit thrombin generation without affecting initial thrombin forming time necessary for platelet activation in hemostasis.

Journal: Journal of thrombosis and haemostasis : JTH 20040401

Title: Acute ischemic stroke successfully treated using sequenced intravenous and intra-arterial thrombolysis and argatroban anticoagulation: a case study.

Journal: Journal of thrombosis and thrombolysis 20040401

Title: Developing an algorithm for treating heparin-induced thrombocytopenia.

Journal: Clinical advances in hematology & oncology : H&O 20040401

Title: Antithrombotic effects of FK419, a novel nonpeptide platelet GPIIb/IIIa antagonist, in a guinea pig photochemically induced middle cerebral artery thrombosis model: comparison with ozagrel and argatroban.

Journal: The Journal of pharmacology and experimental therapeutics 20040301

Title: Argatroban dosing in intensive care patients with acute renal failure and liver dysfunction.

Journal: Pharmacotherapy 20040301

Title: Small-molecule direct antithrombins: argatroban.

Journal: Best practice & research. Clinical haematology 20040301

Title: Treatment of heparin-induced thrombocytopenia: a critical review.

Journal: Archives of internal medicine 20040223

Title: Argatroban as anticoagulant in cardiopulmonary bypass in an infant and attempted reversal with recombinant activated factor VII.

Journal: Anesthesiology 20040201

Title: Failure of argatroban anticoagulation during off-pump coronary artery bypass surgery.

Journal: The Annals of thoracic surgery 20040201

Title: Argatroban use during pediatric interventional cardiac catheterization.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040101

Title: Influence of conduction disturbances on clinical outcome in patients with acute myocardial infarction receiving thrombolysis (results from the ARGAMI-2 study).

Journal: The American journal of cardiology 20040101

Title: Argatroban use in dialysis patients.

Journal: Seminars in dialysis 20040101

Title: Effect of renal function on the pharmacodynamics of argatroban.

Journal: The Annals of pharmacotherapy 20040101

Title: Direct thrombin inhibitors.

Journal: Clinical laboratory science : journal of the American Society for Medical Technology 20040101

Title: Argatroban as an alternative to heparin in extracorporeal membrane oxygenation circuits.

Journal: Perfusion 20040101

Title: Thrombin inhibitor, argatroban, prevents tumor cell migration and bone metastasis.

Journal: Oncology 20040101

Title: Alternatives to heparin infusion.

Journal: Journal of infusion nursing : the official publication of the Infusion Nurses Society 20040101

Title: Argatroban, a new treatment option for heparin-induced thrombocytopenia.

Journal: Critical care nurse 20031201

Title: Predictive value of serial platelet count and VEGF determination for the management of DIC in the Crow-Fukase (POEMS) syndrome.

Journal: Internal medicine (Tokyo, Japan) 20031201

Title: Treatment options for heparin-induced thrombocytopenia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20031015

Title: Argatroban for off-pump coronary artery bypass surgery.

Journal: Anesthesia and analgesia 20031001

Title: Direct thrombin inhibitors for non-ST-segment elevation acute coronary syndromes: what, when, and where?

Journal: American heart journal 20031001

Title: Vascular surgery using argatroban in a patient with a history of heparin-induced thrombocytopenia.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20031001

Title: Differential effects of DX-9065a, argatroban, and synthetic pentasaccharide on tissue thromboplastin inhibition test and dilute Russell's viper venom test.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20031001

Title: Argatroban for heparin-induced thrombocytopenia in hepato-renal failure and CVVHD.

Journal: The Annals of pharmacotherapy 20030901

Title: Decreased argatroban clearance unaffected by hemodialysis in anasarca.

Journal: The Annals of pharmacotherapy 20030901

Title: Antithrombotic properties of a direct thrombin inhibitor with a prolonged half-life and AT-mediated factor Xa inhibitory activity.

Journal: Journal of thrombosis and haemostasis : JTH 20030901

Title: Argatroban inhibits staphylothrombin.

Journal: Journal of thrombosis and haemostasis : JTH 20030901

Title: Argatroban attenuates leukocyte- and platelet-endothelial cell interactions after transient retinal ischemia.

Journal: Stroke 20030801

Title: Effects of argatroban as an anticoagulant for haemodialysis in patients with antithrombin III deficiency.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030801

Title: Argatroban anticoagulation in patients with heparin-induced thrombocytopenia.

Journal: Archives of internal medicine 20030801

Title: Pharmacologic platelet anesthesia by glycoprotein IIb/IIIa complex antagonist and argatroban during in vitro extracorporeal circulation.

Journal: The Journal of thoracic and cardiovascular surgery 20030801

Title: Inhibition of arterial thrombosis by a protease-activated receptor 1 antagonist, FR171113, in the guinea pig.

Journal: European journal of pharmacology 20030725

Title: Obstinate thrombosis during percutaneous coronary intervention in a case with heparin-induced thrombocytopenia with thrombosis syndrome successfully treated by argatroban anticoagulant therapy.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20030701

Title: Direct thrombin inhibitors during PCI.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20030701

Title: Heparin-induced thrombocytopenia--recognition and treatment.

Journal: AORN journal 20030701

Title: Ecarin chromogenic assay--a new method for quantitative determination of direct thrombin inhibitors like hirudin.

Journal: Pathophysiology of haemostasis and thrombosis 20030701

Title: The thrombin inhibitor argatroban does not influence the endothelium-dependent relaxant and contractile responses of isolated rabbit carotid arteries.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601

Title: Excessive argatroban anticoagulation for heparin-induced thrombocytopenia.

Journal: The Annals of pharmacotherapy 20030501

Title: Suppression of argatroban-induced endogenous thrombolysis by PKSI-527, and antibodies to TPA and UPA, evaluated in a rat arterial thrombolysis model.

Journal: Thrombosis and haemostasis 20030501

Title: Successful use of Argatroban as a heparin substitute during cardiopulmonary bypass: heparin-induced thrombocytopenia in a high-risk cardiac surgical patient.

Journal: The Annals of thoracic surgery 20030501

Title: Direct thrombin inhibitors.

Journal: Expert opinion on pharmacotherapy 20030501

Title: Predicting the pharmacology of thrombin inhibitors.

Journal: Journal of thrombosis and haemostasis : JTH 20030501

Title: Management of heparin-induced thrombocytopenia: a critical comparison of lepirudin and argatroban.

Journal: Thrombosis research 20030501

Title: Hemostatic analysis of a patient undergoing off-pump coronary artery bypass surgery with argatroban anticoagulation.

Journal: Anesthesia and analgesia 20030401

Title: Anticoagulation in acute cardiac care in patients with chronic kidney disease.

Journal: American heart journal 20030401

Title: Argatroban as an alternative anticoagulant for patients with heparin allergy during coronary bypass surgery.

Journal: Heart and vessels 20030301

Title: Argatroban, specific thrombin inhibitor, induced phenotype change of cultured rabbit vascular smooth muscle cells.

Journal: European journal of pharmacology 20030207

Title: Heparin-induced thrombocytopenia and cardiopulmonary bypass: perioperative argatroban use.

Journal: The Annals of thoracic surgery 20030201

Title: Characteristics of the hemostatic action of KFA-1411, an inhibitor of coagulation factor Xa (FXa), in humans and various animals.

Journal: The Journal of toxicological sciences 20030201

Title: Clinician update: direct thrombin inhibitors in acute coronary syndromes.

Journal: Journal of thrombosis and thrombolysis 20030201

Title: Acute pulmonary thromboembolism induced by prophylactic heparin use and a heparin-coated catheter: a case of heparin-induced thrombocytopenia and thrombosis syndrome.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20030101

Title: Alternative methods of anticoagulation for dialysis-dependent patients with heparin-induced thrombocytopenia.

Journal: Seminars in dialysis 20030101

Title: Direct thrombin inhibitors in cardiac disease.

Journal: Cardiovascular toxicology 20030101

Title: Effects of argatroban and heparin on thrombus formation and tissue plasminogen activator-induced thrombolysis in a microvascular thrombosis model.

Journal: Thrombosis research 20030101

Title: Argatroban dosing in patients with heparin-induced thrombocytopenia.

Journal: The Annals of pharmacotherapy 20030101

Title: Mild hypothermia enhances the neuroprotective effects of a selective thrombin inhibitor following transient focal ischemia in rats.

Journal: Acta neurochirurgica. Supplement 20030101

Title: Effect of delayed argatroban treatment on intracerebral hemorrhage-induced edema in the rat.

Journal: Acta neurochirurgica. Supplement 20030101

Title: A thrombin inhibitor reduces brain edema, glioma mass and neurological deficits in a rat glioma model.

Journal: Acta neurochirurgica. Supplement 20030101

Title: The effect of dietary bacillus natto productive protein on in vivo endogenous thrombolysis.

Journal: Pathophysiology of haemostasis and thrombosis 20030101

Title: Studies on the different modes of action of the anticoagulant protease inhibitors DX-9065a and Argatroban. II. Effects on fibrinolysis.

Journal: The Journal of biological chemistry 20021227

Title: Studies on the different modes of action of the anticoagulant protease inhibitors DX-9065a and Argatroban. I. Effects on thrombin generation.

Journal: The Journal of biological chemistry 20021227

Title: Thrombosis increases circulatory hepatocyte growth factor by degranulation of mast cells.

Journal: Circulation 20021210

Title: Delayed argatroban treatment reduces edema in a rat model of intracerebral hemorrhage.

Journal: Stroke 20021201

Title: Argatroban in adult extracorporeal membrane oxygenation.

Journal: The journal of extra-corporeal technology 20021201

Title: Lack of pharmacokinetic interactions between argatroban and warfarin.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20021101

Title: Low-molecular weight heparin: treatment failure in a patient with primary antiphospholipid antibody syndrome.

Journal: The American journal of the medical sciences 20021101

Title: Influence of lepirudin, argatroban, and melagatran on prothrombin time and additional effect of oral anticoagulation.

Journal: Clinical chemistry 20021001

Title: Argatroban anticoagulation during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20021001

Title: Argatroban for percutaneous coronary interventions: hit or miss?

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20021001

Title: Hirudin in heparin-induced thrombocytopenia.

Journal: Seminars in thrombosis and hemostasis 20021001

Title: Visual compatibility of argatroban with selected drugs.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020915

Title: Current agents for the treatment of patients with heparin-induced thrombocytopenia.

Journal: Current opinion in pulmonary medicine 20020901

Title: Comment: treatment of heparin-induced thrombocytopenia.

Journal: The Annals of pharmacotherapy 20020901

Title: Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia.

Journal: American journal of hematology 20020901

Title: Preventing complications in heparin-induced thrombocytopenia. Alternative anticoagulants are improving patient outcomes.

Journal: Postgraduate medicine 20020901

Title: Antithrombotic drugs for the treatment of heparin-induced thrombocytopenia.

Journal: Current opinion in investigational drugs (London, England : 2000) 20020801

Title: [Experimental and clinical results with the thrombin inhibitor Argatroban].

Journal: Hamostaseologie 20020801

Title: Monitoring of anticoagulant effects of direct thrombin inhibitors.

Journal: Seminars in thrombosis and hemostasis 20020801

Title: Investigation of the interaction between argatroban and acetaminophen, lidocaine, or digoxin.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020701

Title: Monitoring of argatroban in ARG310 study: potential recommendations for its use in interventional cardiology.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20020701

Title: Direct antithrombin agents ameliorate disseminated intravascular coagulation in suspected heparin-induced thrombocytopenia thrombosis syndrome.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20020701

Title: The role of thrombin inhibition during percutaneous coronary intervention.

Journal: Pharmacotherapy 20020601

Title: [Heparin-induced thrombocytopenia: the clinical picture and treatment].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20020601

Title: Anticoagulant therapy with a selective thrombin inhibitor for acute cerebral infarction: usefulness of coagulation markers for evaluation of efficacy.

Journal: Journal of thrombosis and thrombolysis 20020601

Title: Combined argatroban and edaravone caused additive neuroprotection against 15 min of forebrain ischemia in gerbils.

Journal: Neuroscience research 20020501

Title: Long-term inhibition of nitric oxide synthesis increases arterial thrombogenecity in rat carotid artery.

Journal: American journal of physiology. Heart and circulatory physiology 20020401

Title: Direct thrombin inhibitors for percutaneous coronary intervention in the current era of platelet glycoprotein IIb/IIIa inhibition.

Journal: Journal of interventional cardiology 20020401

Title: Treatment of heparin-induced thrombocytopenia.

Journal: The Annals of pharmacotherapy 20020301

Title: Argatroban therapy does not generate antibodies that alter its anticoagulant activity in patients with heparin-induced thrombocytopenia.

Journal: Thrombosis research 20020301

Title: Inhibitors of fibrinolytic components play different roles in the formation and removal of arterial thrombus in mice.

Journal: Journal of cardiovascular pharmacology 20020201

Title: Platelet shape changes and adhesion under high shear flow.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20020201

Title: Substitution of Gly-548 to Ala in the substrate binding pocket of prothrombin Perijá leads to the loss of thrombin proteolytic activity.

Journal: Thrombosis and haemostasis 20020201

Title: An antibody that binds to primary specific pocket-associated structure in the active site of bovine thrombin.

Journal: Hybridoma and hybridomics 20020201

Title: Argatroban.

Journal: Journal of thrombosis and thrombolysis 20020201

Title: Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data.

Journal: Lancet (London, England) 20020126

Title: [Intraoperative management for a patient with heparin-induced thrombocytopenia (HIT) undergoing off-pump coronary bypass surgery using argatroban, a direct thrombin inhibitor].

Journal: Masui. The Japanese journal of anesthesiology 20020101

Title: Enhancement of endogenous plasminogen activator-induced thrombolysis by argatroban and APC and its control by TAFI, measured in an arterial thrombolysis model in vivo using rat mesenteric arterioles.

Journal: Thrombosis and haemostasis 20020101

Title: Therapeutic considerations in the management of patients with heparin-induced thrombocytopenia.

Journal: Progress in cardiovascular nursing 20020101

Title: Role of thrombin in CNS damage associated with intracerebral haemorrhage: opportunity for pharmacological intervention?

Journal: CNS drugs 20020101

Title: Effect of phenprocoumon on monitoring of lepirudin, argatroban, melagatran and unfractionated heparin with the PiCT method.

Journal: Pathophysiology of haemostasis and thrombosis 20020101

Title: An overview of the direct thrombin inhibitor argatroban.

Journal: Pathophysiology of haemostasis and thrombosis 20020101

Title: Development of argatroban as an anticoagulant and antithrombin agent in Japan.

Journal: Pathophysiology of haemostasis and thrombosis 20020101

Title: Argatroban in thrombotic stroke.

Journal: Pathophysiology of haemostasis and thrombosis 20020101

Title: Argatroban in HIT type II and acute coronary syndrome.

Journal: Pathophysiology of haemostasis and thrombosis 20020101

Title: Practical issues in the development of argatroban: a perspective.

Journal: Pathophysiology of haemostasis and thrombosis 20020101

Title: The use of argatroban as an anticoagulant for cardiopulmonary bypass in cardiac operations.

Journal: The Journal of thoracic and cardiovascular surgery 20011201

Title: Changes in blood viscosity by heparin and argatroban.

Journal: Thrombosis research 20011201

Title: The antithrombotic efficacy of AT-1459, a novel, direct thrombin inhibitor, in rat models of venous and arterial thrombosis.

Journal: Thrombosis and haemostasis 20011201

Title: Successful use of argatroban as an anticoagulant in burn-related severe acquired antithrombin III deficiency after heparin failure.

Journal: Thrombosis and haemostasis 20011201

Title: [Strategy for circulatory disturbance].

Journal: Rinsho shinkeigaku = Clinical neurology 20011201

Title: Extension of the therapeutic window for recombinant tissue plasminogen activator with argatroban in a rat model of embolic stroke.

Journal: Stroke 20011101

Title: Anticoagulation with a selective thrombin inhibitor in a woman with heparin-induced thrombocytopenia.

Journal: Obstetrics and gynecology 20011101

Title: Argatroban.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20011101

Title: A synopsis of the clinical uses of argatroban.

Journal: Journal of thrombosis and thrombolysis 20011001

Title: Alternatives to unfractionated heparin for anticoagulation in cardiopulmonary bypass.

Journal: Perfusion 20010901

Title: A short synthesis of argatroban. a potent selective thrombin inhibitor.

Journal: Bioorganic & medicinal chemistry letters 20010806

Title: Thrombin promotes fibroblast proliferation during the early stages of experimental radiation pneumonitis.

Journal: Radiation research 20010701

Title: Broad-spectrum and selective serine protease inhibitors prevent expression of platelet-derived growth factor-BB and cerebral vasospasm after subarachnoid hemorrhage: vasospasm caused by cisternal injection of recombinant platelet-derived growth factor-BB.

Journal: Stroke 20010701

Title: Anticoagulation: the present and future.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20010701

Title: Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia.

Journal: Brain research 20010601

Title: Direct thrombin inhibitors: are they the future of anticoagulation?

Journal: South Dakota journal of medicine 20010601

Title: Advances in the development of thrombin inhibitors.

Journal: Expert opinion on investigational drugs 20010501

Title: Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia.

Journal: Circulation 20010410

Title: Argatroban for prevention and treatment of thromboembolism in heparin-induced thrombocytopenia.

Journal: The Annals of pharmacotherapy 20010401

Title: Heparin induced thrombocytopenia thrombosis (HIT/T) syndrome: diagnosis and treatment.

Journal: Journal of clinical pathology 20010401

Title: [Direct thrombin antagonists].

Journal: Herz 20010401

Title: Off-pump coronary artery bypass for a heparin-allergic patient.

Journal: The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi 20010401

Title: A specific thrombin inhibitor, argatroban, alleviates herpes zoster-associated pain.

Journal: The Journal of dermatology 20010401

Title: Interpreting the International Normalized Ratio (INR) in individuals receiving argatroban and warfarin.

Journal: Thrombosis and haemostasis 20010301

Title: Argatroban for treatment of heparin-induced thrombocytopenia.

Journal: The Medical letter on drugs and therapeutics 20010205

Title: Antithrombotic effects of a synthetic inhibitor of activated factor X, JTV-803, in animals.

Journal: European journal of pharmacology 20010119

Title: [Specific inhibition of thrombin activity during cardiopulmonary bypass reduces ischemia-reperfusion injury of the lung].

Journal: Fukuoka igaku zasshi = Hukuoka acta medica 20010101

Title: Argatroban.

Journal: Drugs 20010101

Title: Enhanced thrombolysis induced by argatroban or activated protein C in the presence or absence of staphylokinase, measured in an in vivo animal model using mesenteric arterioles.

Journal: Haemostasis 20010101

Title: Argatroban: a direct thrombin inhibitor for heparin-induced thrombocytopenia and other clinical applications.

Journal: Heart disease (Hagerstown, Md.) 20010101

Title: In vitro antiplatelet profile of FR171113, a novel non-peptide thrombin receptor antagonist.

Journal: European journal of pharmacology 19991119

Title: Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban.

Journal: Thrombosis and haemostasis 19990201

Title: The first report of successful carotid stent implant using argatroban anticoagulation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome: a case report.

Journal: Angiology 19980101

Title: Inhibition of collagen-induced platelet aggregation by argatroban in patients with acute cerebral infarction.

Journal: Thrombosis research 19971015

Title: Anticoagulation with Novastan (argatroban) in patients with heparin-induced thrombocytopenia and heparin-induced thrombocytopenia and thrombosis syndrome.

Journal: Seminars in thrombosis and hemostasis 19970101

Title: Kawada, T., et al., Argatroban, an attractive anticoagulant, for left heart bypass with centrifugal pump for repair of traumatic aortic rupture. Jpn J Thorac Cardiovasc Surg, 1999. 47(3): p. 104-9.

Title: Jang, I.K., et al., A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol, 1999. 33(7): p. 1879-85.

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Tags:141396-28-3 Molecular Formula|141396-28-3 MDL|141396-28-3 SMILES|141396-28-3 Argatroban monohydrate |Heterocyclic_Building_Blocks