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14293-44-8,MFCD00865927
Catalog No.:AA00HWNZ

14293-44-8 | Xipamide

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1mg
97%
in stock  
$7.00   $5.00
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10mg
97%
in stock  
$17.00   $12.00
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50mg
97%
in stock  
$54.00   $38.00
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100mg
97%
in stock  
$106.00   $75.00
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250mg
97%
in stock  
$200.00   $140.00
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1g
97%
in stock  
$515.00   $361.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00HWNZ
Chemical Name:
Xipamide
CAS Number:
14293-44-8
Molecular Formula:
C15H15ClN2O4S
Molecular Weight:
354.8086
MDL Number:
MFCD00865927
SMILES:
O=C(c1cc(c(cc1O)Cl)S(=O)(=O)N)Nc1c(C)cccc1C
Properties
Computed Properties
 
Complexity:
526  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
2.9  

Downstream Synthesis Route
titanium(III)chloride 
  14293-44-8    7732-18-5   
Ti(4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide)2(H2O)2Cl 

[1]RussianJournalofGeneralChemistry,2018,vol.88,p.767-773    Ross.Khim.Zh.,2018,vol.88,p.767-773,7

nickel(II)sulfatehexahydrate 
  14293-44-8   
Ni(4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide)2(H2O)2 

[1]RussianJournalofGeneralChemistry,2018,vol.88,p.767-773    Ross.Khim.Zh.,2018,vol.88,p.767-773,7

zirconiumoxidechlorideoctahydrate 
  14293-44-8   
ZrO(4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide)2H2O*H2O 

[1]RussianJournalofGeneralChemistry,2018,vol.88,p.767-773    Ross.Khim.Zh.,2018,vol.88,p.767-773,7

14293-44-8    7732-18-5   
palladiumdichloride 
 
Pd(4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide)2*(H2O)2 

[1]RussianJournalofGeneralChemistry,2018,vol.88,p.767-773    Ross.Khim.Zh.,2018,vol.88,p.767-773,7

Literature

Title: Selective and sensitive spectrophotometric method for the determination of trace amounts of zirconium in environmental and biological samples using 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101

Title: Bioavailability study of triamterene and xipamide using urinary pharmacokinetic data following single oral dose of each drug or their combination.

Journal: Journal of pharmaceutical and biomedical analysis 20120305

Title: Performance scores in general practice: a comparison between the clinical versus medication-based approach to identify target populations.

Journal: PloS one 20120101

Title: Spectrophotometric and spectrodensitometric determination of triamterene and xipamide in pure form and in pharmaceutical formulation.

Journal: Drug testing and analysis 20100301

Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal: Journal of medicinal chemistry 20081113

Title: Combined effect of solvent content, temperature and pH on the chromatographic behaviour of ionisable compounds.

Journal: Journal of chromatography. A 20070907

Title: Screening procedure for detection of diuretics and uricosurics and/or their metabolites in human urine using gas chromatography-mass spectrometry after extractive methylation.

Journal: Therapeutic drug monitoring 20050801

Title: Trough levels of mycophenolic acid and its glucuronidated metabolite in renal transplant recipients.

Journal: International journal of clinical pharmacology and therapeutics 20050801

Title: [Mechanism of action of xipamide and its classification as a 'low ceiling diuretic'. Pharmacodynamic-pharmacokinetic studies in healthy volunteers and in kidney and liver patients].

Journal: Arzneimittel-Forschung 20050101

Title: Experimental design optimization of a capillary zone electrophoresis method for the screening of several diuretics and ACE inhibitors.

Journal: Journal of chromatographic science 20040201

Title: Effects of pH and the presence of micelles on the resolution of diuretics by reversed-phase liquid chromatography.

Journal: Journal of chromatography. A 20040102

Title: Determination of Xipamide metabolite in human urine by high-performance liquid chromatography/diode-array detection, high-performance liquid chromatography/electrospray ionization mass spectrometry and gas chromatography/mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: [What did the ALLHAT study bring? To do the one without foregoing the other].

Journal: MMW Fortschritte der Medizin 20031218

Title: [Proven in the practice. Follow up of the use confirms high trial value].

Journal: MMW Fortschritte der Medizin 20031218

Title: [Thiazide analogs. Also can be used in renal failure].

Journal: MMW Fortschritte der Medizin 20030821

Title: Effect of the location of hydrogen abstraction on the fragmentation of diuretics in negative electrospray ionization mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry 20030601

Title: Can xipamide or tacrolimus inhibit the glucuronidation of mycophenolic acid in rat liver slices?

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601

Title: Severe electrolyte disturbances and renal failure in elderly patients with combined diuretic therapy including xipamid.

Journal: Wiener klinische Wochenschrift 20021130

Title: Liver carbonic anhydrase and urea synthesis. The effect of diuretics.

Journal: Biochemical pharmacology 19861001

Title: Ventricular fibrillation induced by xipamide.

Journal: British medical journal (Clinical research ed.) 19820508

Title: Hypokalaemia and xipamide.

Journal: British medical journal (Clinical research ed.) 19820327

Title: Hypotensive effects of xipamide in essential hypertension. Crossover comparison with hydrochlorothiazide.

Journal: Journal of clinical pharmacology 19810701

Title: Prichard BN, et al. Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. Drugs. 1985 Oct;30(4):313-32.

Title: Hannaert P, et al. Beneficial effects of xipamide on pH and Ca2+ ions of cardiac cells. Arch Mal Coeur Vaiss. 1990 Jul;83(8):1271-4.

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