Title: Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin.
Journal: Toxicology letters20180701
Title: Plasma 2-hydroxyglutarate and hexanoylcarnitine levels are potential biomarkers for skeletal muscle toxicity in male Fischer 344 rats.
Journal: The Journal of toxicological sciences20170101
Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
Journal: Chemical research in toxicology20150518
Title: Inhibition of prenyltransferase activity by statins in both liver and muscle cell lines is not causative of cytotoxicity.
Journal: Toxicology20150302
Title: Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action.
Journal: PloS one20140101
Title: Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).
Journal: Toxicological sciences : an official journal of the Society of Toxicology20131201
Title: Detection of statin cytotoxicity is increased in cells expressing the OATP1B1 transporter.
Journal: Toxicological sciences : an official journal of the Society of Toxicology20130701
Title: Combination therapy with an angiotensin II receptor blocker and an HMG-CoA reductase inhibitor in experimental subtotal nephrectomy.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20120701
Title: Effects of cerivastatin on adrenergic pathways, hypertrophic growth and TGFbeta expression in adult ventricular cardiomyocytes.
Journal: European journal of cell biology20120501
Title: A screening study of drug-drug interactions in cerivastatin users: an adverse effect of clopidogrel.
Journal: Clinical pharmacology and therapeutics20120501
Title: The need for translational research on drug-drug interactions.
Journal: Clinical pharmacology and therapeutics20120501
Title: Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins.
Journal: Cell biology and toxicology20120401
Title: Active safety monitoring of new medical products using electronic healthcare data: selecting alerting rules.
Journal: Epidemiology (Cambridge, Mass.)20120301
Title: [Effects of acidification and alkalinization agents on statins-induced muscle toxicity].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan20120101
Title: Multi-species analyses of direct activators of the constitutive androstane receptor.
Journal: Toxicological sciences : an official journal of the Society of Toxicology20111001
Title: Biological perspectives: update on newer antipsychotic drugs: are they evidence based?
Journal: Perspectives in psychiatric care20111001
Title: Cerivastatin induces type-I fiber-, not type-II fiber-, predominant muscular toxicity in the young male F344 rats.
Journal: The Journal of toxicological sciences20110801
Title: Cerivastatin, genetic variants, and the risk of rhabdomyolysis.
Journal: Pharmacogenetics and genomics20110501
Title: Identification of 1- and 3-methylhistidine as biomarkers of skeletal muscle toxicity by nuclear magnetic resonance-based metabolic profiling.
Journal: Analytical biochemistry20110301
Title: Cerivastatin in vitro metabolism by CYP2C8 variants found in patients experiencing rhabdomyolysis.
Journal: Pharmacogenetics and genomics20101001
Title: Apolipoprotein B100 secretion by cultured ARPE-19 cells is modulated by alteration of cholesterol levels.
Journal: Journal of neurochemistry20100901
Title: Polymer-free cerivastatin-eluting stent shows superior neointimal inhibition with preserved vasomotor function compared to polymer-based paclitaxel-eluting stent in rabbit iliac arteries.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology20100501
Title: Quantitative phenotyping via deep barcode sequencing.
Journal: Genome research20091001
Title: Biomarkers of drug-induced skeletal muscle injury in the rat: troponin I and myoglobin.
Journal: Toxicological sciences : an official journal of the Society of Toxicology20091001
Title: Rhabdomyolysis a result of azithromycin and statins: an unrecognized interaction.
Journal: British journal of clinical pharmacology20090901
Title: [Metabolic rhabdomyolysis during statin therapy].
Journal: La Revue de medecine interne20090801
Title: Autocrine amplification loop in statin-induced apoptosis of human melanoma cells.
Journal: British journal of pharmacology20090801
Title: Statin-induced liver injury involves cross-talk between cholesterol and selenoprotein biosynthetic pathways.
Journal: Molecular pharmacology20090601
Title: Statin-induced myopathy in the rat: relationship between systemic exposure, muscle exposure and myopathy.
Journal: Xenobiotica; the fate of foreign compounds in biological systems20090101
Title: The social costs of dangerous products: an empirical investigation.
Journal: Cornell journal of law and public policy20090101
Title: [Anticoagulation in atrial fibrillation].
Journal: Hamostaseologie20081001
Title: Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention.
Journal: International journal of cancer20080901
Title: Effect of APOE genotype on lipid levels in patients with coronary heart disease during a 3-week inpatient rehabilitation program.
Journal: Clinical pharmacology and therapeutics20080801
Title: Prediction of the pharmacokinetics of atorvastatin, cerivastatin, and indomethacin using kinetic models applied to isolated rat hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals20080701
Title: Effects of cerivastatin withdrawal on statin persistence.
Journal: The Annals of pharmacotherapy20080701
Title: Effects of different statins on endothelial nitric oxide synthase and AKT phosphorylation in endothelial cells.
Journal: International journal of cardiology20080623
Title: Severe obstructive sleep apnea after cerivastatin therapy: a case report.
Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine20080615
Title: Effectiveness of statin-eluting stent on early inflammatory response and neointimal thickness in a porcine coronary model.
Journal: Circulation journal : official journal of the Japanese Circulation Society20080501
Title: 3-Hydroxy-3-methylglutaryl coenzyme A reductase in rainbow trout: effects of fasting and statin drugs on activities and mRNA transcripts.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP20080401
Title: Apolipoprotein E genotypes are associated with lipid-lowering responses to statin treatment in diabetes: a Go-DARTS study.
Journal: Pharmacogenetics and genomics20080401
Title: Statin (cerivastatin) protects mice against sepsis-related death via reduced proinflammatory cytokines and enhanced bacterial clearance.
Journal: Surgical infections20080401
Title: Estimating the extent of reporting to FDA: a case study of statin-associated rhabdomyolysis.
Journal: Pharmacoepidemiology and drug safety20080301
Title: Metabolic myopathies discovered during investigations of statin myopathy.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques20080301
Title: Statins attenuate polymethylmethacrylate-mediated monocyte activation.
Journal: Acta orthopaedica20080201
Title: Early detection of adverse drug events within population-based health networks: application of sequential testing methods.
Journal: Pharmacoepidemiology and drug safety20071201
Title: Isoprenoid-independent pathway is involved in apoptosis induced by risedronate, a bisphosphonate, in which Bim plays a critical role in breast cancer cell line MCF-7.
Journal: Oncology reports20071101
Title: A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in vivo.
Journal: Calcified tissue international20071101
Title: Flow cytometric evaluation of synergistic pro-apoptotic effects of statins and clofibrates in IM-9 human lymphoblasts.
Journal: Clinical and experimental pharmacology & physiology20070901
Title: Isoprenoid depletion by statins antagonizes cytokine-induced down-regulation of endothelial nitric oxide expression and increases NO synthase activity in human umbilical vein endothelial cells.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20070901
Title: Preventive effects of bicarbonate on cerivastatin-induced apoptosis.
Journal: International journal of pharmaceutics20070816
Title: Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs.
Journal: Toxicology and applied pharmacology20070815
Title: [Rhabdomyolysis induced by statins].
Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine20070810
Title: Effect of cerivastatin on peripheral capillary permeability to albumin and peripheral nerve function in diabetic rats.
Journal: Diabetes & metabolism20070601
Title: The HMG-CoA reductase inhibitor cerivastatin lowers advanced glycation end products in patients with type 2 diabetes.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association20070601
Title: Nephroprotective effect of the HMG-CoA-reductase inhibitor cerivastatin in a mouse model of progressive renal fibrosis in Alport syndrome.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20070401
Title: Pharmacogenetics and pharmacogenomics of cholesterol-lowering therapy.
Journal: Current opinion in lipidology20070401
Title: Statins attenuate ischemia-reperfusion injury by inducing heme oxygenase-1 in infiltrating macrophages.
Journal: The American journal of pathology20070401
Title: Subcutaneous administration of lactone form of simvastatin stimulates ectopic osteoinduction by rhBMP-2.
Journal: Oral diseases20070301
Title: Dose-dependent effects of docosahexaenoic acid supplementation on blood lipids in statin-treated hyperlipidaemic subjects.
Journal: Lipids20070301
Title: Cerivastatin reduces cytokine-induced surface expression of ICAM-1 via increased shedding in human endothelial cells.
Journal: Atherosclerosis20070101
Title: Molecular basis of differences among statins and a comparison with antioxidant vitamins.
Journal: The American journal of cardiology20061204
Title: RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation.
Journal: Cell death and differentiation20061101
Title: Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line.
Journal: Metabolism: clinical and experimental20061101
Title: Formulary committees and Medicare Part D.
Journal: Journal of the American Geriatrics Society20061101
Title: Toxicity of statins on rat skeletal muscle mitochondria.
Journal: Cellular and molecular life sciences : CMLS20061001
Title: Single administration of cerivastatin, an HMG-CoA reductase inhibitor, improves the coronary flow velocity reserve: a transthoracic Doppler echocardiography study.
Journal: Heart and vessels20060901
Title: Inhibitory effects of statins on human monocarboxylate transporter 4.
Journal: International journal of pharmaceutics20060706
Title: Differential effects of different statins on endothelin-1 gene expression and endothelial NOS phosphorylation in porcine aortic endothelial cells.
Journal: Experimental biology and medicine (Maywood, N.J.)20060601
Title: Clinical trials in the wake of Vioxx: requiring statistically extreme evidence of benefit to ensure the safety of new drugs.
Journal: Circulation20060509
Title: Statins blunt thrombin-induced down-regulation of endothelial nitric oxide synthase expression in human endothelial cells.
Journal: Journal of cardiovascular pharmacology20060501
Title: Statin safety: an assessment using an administrative claims database.
Journal: The American journal of cardiology20060417
Title: Statins prevent NF-kappaB transactivation independently of the IKK-pathway in human endothelial cells.
Journal: Atherosclerosis20060401
Title: Effects of various statins on cytokine-dependent growth and IgE-dependent release of histamine in human mast cells.
Journal: Allergy20060301
Title: Hydroxymethylglutaryl-CoA reductase inhibitors in older persons with acute myocardial infarction: evidence for an age-statin interaction.
Journal: Journal of the American Geriatrics Society20060301
Title: Statins and osteoporosis: new role for old drugs.
Journal: The Journal of pharmacy and pharmacology20060101
Title: Cerivastatin and hypercholesterolemia reduce apoptosis of cardiomyocytes in guinea pig papillary muscle subjected to hypoxia/reoxygenation.
Journal: Pharmacological reports : PR20060101
Title: Statins prevent pulsatile stretch-induced proliferation of human saphenous vein smooth muscle cells via inhibition of Rho/Rho-kinase pathway.
Journal: Cardiovascular research20051201
Title: Local statin therapy differentially interferes with smooth muscle and endothelial cell proliferation and reduces neointima on a drug-eluting stent platform.
Journal: Cardiovascular research20051201
Title: Roles of exercise and pharmacokinetics in cerivastatin-induced skeletal muscle toxicity.
Journal: Toxicological sciences : an official journal of the Society of Toxicology20051201
Title: Oxidized-LDL levels are changed during short-term serum glucose variations and lowered with statin treatment in early Type 2 diabetes: a study of endothelial function and microalbuminuria.
Journal: Diabetic medicine : a journal of the British Diabetic Association20051201
Title: Microvascular endothelial function in subjects with Type 2 diabetes and the effect of lipid-lowering therapy.
Journal: Diabetic medicine : a journal of the British Diabetic Association20051201
Title: The effect of six different statins on the proliferation, migration, and invasion of human smooth muscle cells.
Journal: The Journal of surgical research20051101
Title: Statins and PPARalpha agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co-treatment.
Journal: Toxicology and applied pharmacology20051101
Title: Statin-induced apoptosis linked with membrane farnesylated Ras small G protein depletion, rather than geranylated Rho protein.
Journal: The Journal of pharmacy and pharmacology20051101
Title: Differential associations of statin and fibrate treatment with carotid arterial remodeling.
Journal: American journal of hypertension20051101
Title: Evaluation of apoptosis and necrosis induced by statins using fluorescence-enhanced flow cytometry.
Journal: Journal of pharmaceutical and biomedical analysis20050915
Title: Binding thermodynamics of statins to HMG-CoA reductase.
Journal: Biochemistry20050906
Title: Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multidrug resistance 1, and OATP1B1/breast cancer resistance protein.
Journal: The Journal of pharmacology and experimental therapeutics20050901
Title: Differences between statins on clinical endpoints: a population-based cohort study.
Journal: Current medical research and opinion20050901
Title: Using Crestor--and all statins--safely. Some simple steps can help minimize or avoid muscle problems from these cholesterol-lowering drugs.
Journal: Harvard heart letter : from Harvard Medical School20050901
Title: Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin.
Journal: The Journal of pharmacology and experimental therapeutics20050801
Title: New light on statin side effects. What recent research on the cholesterol drugs means to you.
Journal: Heart advisor20050801
Title: Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor.
Journal: Drug metabolism and disposition: the biological fate of chemicals20050701
Title: Combination therapy with cerivastatin and nifedipine improves endothelial dysfunction after balloon injury in porcine coronary arteries.
Journal: Journal of cardiovascular pharmacology20050701
Title: Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells.
Journal: Pharmacogenetics and genomics20050701
Title: The effect of statin therapy on endothelial function in type 2 diabetes without manifest cardiovascular disease.
Journal: Diabetes care20050701
Title: No effect of statin therapy on silent myocardial ischemia in patients with type 2 diabetes without manifest cardiovascular disease.
Journal: Diabetes care20050701
Title: In vivo and in vitro effects of statins on lymphocytes in patients with Hashimoto's thyroiditis.
Journal: European journal of endocrinology20050701
Title: The issue of statin safety: where do we stand?
Journal: Circulation20050614
Title: The safety of rosuvastatin as used in common clinical practice: a postmarketing analysis.
Journal: Circulation20050614
Title: Intense cholesterol lowering therapy with a HMG-CoA reductase inhibitor does not improve nitric oxide dependent endothelial function in type-2-diabetes--a multicenter, randomised, double-blind, three-arm placebo-controlled clinical trial.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association20050601
Title: Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells.
Journal: Carcinogenesis20050501
Title: Functional characterization of five novel CYP2C8 variants, G171S, R186X, R186G, K247R, and K383N, found in a Japanese population.
Journal: Drug metabolism and disposition: the biological fate of chemicals20050501
Title: Effects of cerivastatin on forearm vascular responses, blood pressure responsiveness and ambulatory blood pressure in type 2 diabetic men.
Journal: Diabetes, obesity & metabolism20050501
Title: Two-year statin therapy does not alter the progression of intima-media thickness in patients with type 2 diabetes without manifest cardio-vascular disease: response to Beishuizen et al.
Journal: Diabetes care20050501
Title: More on: fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells.
Journal: Journal of thrombosis and haemostasis : JTH20050501
Title: Clearance rates of cerivastatin metabolites in a patient with cerivastatin-induced rhabdomyolysis.
Journal: Journal of clinical pharmacy and therapeutics20050401
Title: Lipid-independent effects of statins on endothelial function and bioavailability of nitric oxide in hypercholesterolemic patients.
Journal: American heart journal20050301
Title: Influence of coenzyme Q(10) and cerivastatin on the flow-mediated vasodilation of the brachial artery: results of the ENDOTACT study.
Journal: International journal of cardiology20050227
Title: Statins suppress oxidized low density lipoprotein-induced macrophage proliferation by inactivation of the small G protein-p38 MAPK pathway.
Journal: The Journal of biological chemistry20050225
Title: Relaxant effects of pravastatin, atorvastatin and cerivastatin on isolated rat aortic rings.
Journal: Life sciences20050225
Title: Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy20050201
Title: Improvement of arterial stiffness by the antioxidant and anti-inflammatory effects of short-term statin therapy in patients with hypercholesterolemia.
Journal: Heart and vessels20050201
Title: Effects of switching pravastatin to cerivastatin on C-reactive protein, butyrylcholinesterase, and lipids.
Journal: Current medical research and opinion20050201
Title: Differential effect of cerivastatin and L-arginine on the vascular function of human radial and left internal thoracic arteries.
Journal: Journal of cardiac surgery20050101
Title: Statin-induced muscle necrosis in the rat: distribution, development, and fibre selectivity.
Journal: Toxicologic pathology20050101
Title: Analysis of the global RNA expression profiles of skeletal muscle cells treated with statins.
Journal: Journal of atherosclerosis and thrombosis20050101
Title: Mechanisms of calcium release from the sarcoplasmic reticulum in skeletal muscle.
Journal: Advances in experimental medicine and biology20050101
Title: [Severe muscle disorders associated with statins: analysis of cases notified in France up to the end of February 2002 and data concerning the risk profile of cerivastatin].
Journal: Therapie20050101
Title: [Comparison of reports from patients and health professionals: statins and muscle disorders].
Journal: Therapie20050101
Title: Acute effect of cerivastatin on cardiac regional ischemia in a rat model mimicking off-pump coronary surgery.
Journal: Journal of cardiac surgery20050101
Title: [Withdrawal of cerivastatin revealed a flaw of post-marketing surveillance system in the United States].
Journal: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences20050101
Title: In vitro and in vivo correlation of the inhibitory effect of cyclosporin A on the transporter-mediated hepatic uptake of cerivastatin in rats.
Journal: Drug metabolism and disposition: the biological fate of chemicals20041201
Title: Two-year statin therapy does not alter the progression of intima-media thickness in patients with type 2 diabetes without manifest cardiovascular disease.
Journal: Diabetes care20041201
Title: Potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysis.
Journal: JAMA20041201
Title: Potential for conflict of interest in the evaluation of suspected adverse drug reactions: a counterpoint.
Journal: JAMA20041201
Title: Bayer's response to 'potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysis'.
Journal: JAMA20041201
Title: The effect of statins on angiotensin II-induced hemodynamic changes in young, mildly hypercholesterolemic men.
Journal: American journal of hypertension20041201
Title: Statins inhibit in vitro calcification of human vascular smooth muscle cells induced by inflammatory mediators.
Journal: Journal of cellular biochemistry20041115
Title: Simple, sensitive and rapid LC-MS/MS method for the quantitation of cerivastatin in human plasma--application to pharmacokinetic studies.
Journal: Journal of pharmaceutical and biomedical analysis20041115
Title: Rosuvastatin safety: lessons from the FDA review and post-approval surveillance.
Journal: Expert opinion on drug safety20041101
Title: Statin and fibrate treatment of combined hyperlipidemia: the effects on some novel risk factors.
Journal: Thrombosis and haemostasis20041101
Title: The effect of cerivastatin therapy on vascular responses to endothelin antagonists in humans.
Journal: Journal of cardiovascular pharmacology20041101
Title: Optimal windows of statin use for immediate infarct limitation: 5'-nucleotidase as another downstream molecule of phosphatidylinositol 3-kinase.
Journal: Circulation20041012
Title: Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil.
Journal: The Journal of pharmacology and experimental therapeutics20041001
Title: Simvastatin and survival in sepsis.
Journal: Circulation20040921
Title: Abrogation of insulin-like growth factor-I (IGF-I) and insulin action by mevalonic acid depletion: synergy between protein prenylation and receptor glycosylation pathways.
Journal: The Journal of biological chemistry20040910
Title: Overexpression of neural cell adhesion molecule in regenerative muscle fibers in 3-hydroxy-3-methylglutaryl coenzyme: A reductase inhibitor-induced rhabdomyolysis.
Journal: Applied immunohistochemistry & molecular morphology : AIMM20040901
Title: Bayer to settle lawsuits over Baycol.
Journal: Health news (Waltham, Mass.)20040901
Title: Angiogenesis and vasculogenesis are impaired in the precocious-aging klotho mouse.
Journal: Circulation20040831
Title: Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia.
Journal: Arteriosclerosis, thrombosis, and vascular biology20040801
Title: The cerivastatin withdrawal crisis: a 'post-mortem' analysis.
Journal: Health policy (Amsterdam, Netherlands)20040801
Title: Combined antihypertensive and lipid-lowering treatment.
Journal: Current hypertension reports20040801
Title: Different effects of pravastatin and cerivastatin on the media of the carotid arteries as assessed by integrated backscatter ultrasound.
Journal: Circulation journal : official journal of the Japanese Circulation Society20040801
Title: Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice.
Journal: Naunyn-Schmiedeberg's archives of pharmacology20040801
Title: Effect of cerivastatin on endothelial dysfunction and aortic CD36 expression in diabetic hyperlipidemic rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension20040801
Title: Statins inhibit beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes via a Rac1-dependent mechanism.
Journal: Circulation20040727
Title: Hypochlorous acid, a macrophage product, induces endothelial apoptosis and tissue factor expression: involvement of myeloperoxidase-mediated oxidant in plaque erosion and thrombogenesis.
Journal: Arteriosclerosis, thrombosis, and vascular biology20040701
Title: Statins augment collateral growth in response to ischemia but they do not promote cancer and atherosclerosis.
Journal: Hypertension (Dallas, Tex. : 1979)20040601
Title: Cerivastatin demonstrates enhanced antitumor activity against human breast cancer cell lines when used in combination with doxorubicin or cisplatin.
Journal: International journal of oncology20040501
Title: Inhibition of HMG-CoA reductase with cerivastatin lowers dense low density lipoproteins in patients with elevated fasting glucose, impaired glucose tolerance and type 2 diabetes mellitus.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association20040501
Title: Cerivastatin activates endothelial calcium-activated potassium channels and thereby modulates endothelial nitric oxide production and cell proliferation.
Journal: Journal of the American Society of Nephrology : JASN20040401
Title: Cerivastatin-induced polymyalgia rheumatica-like illness.
Journal: Clinical rheumatology20040401
Title: Time course differences for statin-induced pleiotropic effects in hypercholesterolemic patients.
Journal: International journal of cardiology20040301
Title: Site-specific effects of cerivastatin on bone in male Sprague-Dawley rats.
Journal: Bone20040301
Title: Cerivastatin inhibits proliferation of interleukin-1 beta-induced rat mesangial cells by enhanced formation of nitric oxide.
Journal: European journal of pharmacology20040206
Title: Early detection of drug interactions utilizing a computerized drug prescription handling system-focus on cerivastatin-gemfibrozil.
Journal: European journal of clinical pharmacology20040201
Title: Beneficial effects of statins in patients with non-ischemic heart failure.
Journal: Zeitschrift fur Kardiologie20040201
Title: Failure to continue lipid-lowering drug use following the withdrawal of cerivastatin.
Journal: Drug safety20040101
Title: Evaluation of ubiquinone concentration and mitochondrial function relative to cerivastatin-induced skeletal myopathy in rats.
Journal: Toxicology and applied pharmacology20040101
Title: Cerivastatin-induced apoptosis of human aortic smooth muscle cells through partial inhibition of basal activation of extracellular signal-regulated kinases.
Journal: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology20040101
Title: The influence of statins on the free intracellular calcium concentration in human umbilical vein endothelial cells.
Journal: BMC cardiovascular disorders20040101
Title: Cerivastatin does not prevent oxidative injury of human aortic endothelial cells.
Journal: Texas Heart Institute journal20040101
Title: A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin.
Journal: Journal of human genetics20040101
Title: Differential in vitro response of the human radial artery versus left internal thoracic artery to cerivastatin: implications to bypass grafting.
Journal: The Annals of thoracic surgery20031201
Title: Inhibition of hydroxymethylglutaryl-coenzyme a reductase reduces Th1 development and promotes Th2 development.
Journal: Circulation research20031114
Title: HMG-CoA reductase inhibition reduces the proinflammatory activation of human vascular smooth muscle cells by the terminal complement factor C5b-9.
Journal: Basic research in cardiology20031101
Title: Determination of the pharmacokinetics of cerivastatin when administered in combination with sirolimus and cyclosporin A in patients with kidney transplant, and review of the relevant literature.
Journal: International journal of clinical pharmacology and therapeutics20031101
Title: Ca2+-releasing effect of cerivastatin on the sarcoplasmic reticulum of mouse and rat skeletal muscle fibers.
Journal: Journal of pharmacological sciences20031101
Title: Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier: high affinity transporter for thyroxine.
Journal: The Journal of biological chemistry20031031
Title: Direct anti-inflammatory mechanisms contribute to attenuation of experimental allograft arteriosclerosis by statins.
Journal: Circulation20031028
Title: Withdrawal of cerivastatin induces monocyte chemoattractant protein 1 and tissue factor expression in cultured vascular smooth muscle cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology20031001
Title: Skeletal reconstruction by vascularized allogenic bone transplantation: effects of statin in rats.
Journal: Transplantation20030915
Title: Cardiac magnetic resonance imaging in small animal models of human heart failure.
Journal: Medical image analysis20030901
Title: Cerivastatin monotherapy-induced muscle weakness, rhabdomyolysis and acute renal failure.
Journal: International journal of cardiology20030901
Title: Platelet hyperactivity after statin treatment discontinuation.
Journal: Thrombosis and haemostasis20030901
Title: The HMG-CoA reductase inhibitor cerivastatin enhances the nitric oxide bioavailability of the endothelium.
Journal: Journal of cardiovascular pharmacology20030901
Title: Second hand smoke stimulates tumor angiogenesis and growth.
Journal: Cancer cell20030901
Title: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors prevent the development of cardiac hypertrophy and heart failure in rats.
Journal: Journal of molecular and cellular cardiology20030801
Title: Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol-lowering activity of (-)-3S,5R-fluvastatin and (+)-3R,5S-fluvastatin in healthy volunteers.
Journal: Clinical pharmacology and therapeutics20030801
Title: Tacrolimus and cerivastatin pharmacokinetics and adverse effects after single and multiple dosing with cerivastatin in renal transplant recipients.
Journal: British journal of clinical pharmacology20030801
Title: HMG-CoA reductase inhibitor cerivastatin inhibits interleukin-6 expression and secretion in human adipocytes.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme20030801
Title: Hydroxymethylglutaryl coenzyme A reductase inhibition reduces Chlamydia pneumoniae-induced cell interaction and activation.
Journal: Circulation20030722
Title: Intestinal pseudobstruction as presenting event of fatal cerivastatin-induced myopathy.
Journal: Journal of neurology20030701
Title: Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins.
Journal: Molecular and cellular biochemistry20030701
Title: Of cancer and cholesterol: studies elucidate anticancer mechanisms of statins.
Journal: Journal of the National Cancer Institute20030618
Title: Preventive effect of cerivastatin on diabetic nephropathy through suppression of glomerular macrophage recruitment in a rat model.
Journal: Diabetologia20030601
Title: Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages.
Journal: Arteriosclerosis, thrombosis, and vascular biology20030501
Title: Combination lipid-lowering therapy with statins: safety issues in the postcerivastatin era.
Journal: Expert opinion on drug safety20030501
Title: Vascular smooth muscle cell activation by C-reactive protein.
Journal: Cardiovascular research20030401
Title: The effect of early treatment by cerivastatin on the serum level of C-reactive protein, interleukin-6, and interleukin-8 in the patients with unstable angina and non-Q-wave myocardial infarction.
Journal: Molecular and cellular biochemistry20030401
Title: Safety and statin therapy: reconsidering the risks and benefits.
Journal: Archives of internal medicine20030324
Title: Bayer is forced to release documents over withdrawal of cerivastatin.
Journal: BMJ (Clinical research ed.)20030308
Title: How a statin might destroy a drug company.
Journal: Lancet (London, England)20030308
Title: Molecular mechanism of the anti-cancer activity of cerivastatin, an inhibitor of HMG-CoA reductase, on aggressive human breast cancer cells.
Journal: Cellular signalling20030301
Title: Statins and myotoxicity.
Journal: Current atherosclerosis reports20030301
Title: Effects of cerivastatin on human arterial smooth muscle cell growth and extracellular matrix expression at varying glucose and low-density lipoprotein levels.
Journal: Journal of cardiovascular pharmacology20030301
Title: Simvastatin reduces the expression of adhesion molecules in circulating monocytes from hypercholesterolemic patients.
Journal: Arteriosclerosis, thrombosis, and vascular biology20030301
Title: Insights in the molecular mechanisms of the anti-angiogenic effect of an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Journal: Thrombosis and haemostasis20030301
Title: Statins and myotoxicity.
Journal: Trends in pharmacological sciences20030301
Title: Cytochrome P450 epoxygenases and vascular tone: novel role for HMG-CoA reductase inhibitors in the regulation of CYP 2C expression.
Journal: Biochimica et biophysica acta20030217
Title: HMG-CoA reductase inhibitor enhances inducible nitric oxide synthase expression in rat vascular smooth muscle cells; involvement of the Rho/Rho kinase pathway.
Journal: Atherosclerosis20030201
Title: Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A.
Journal: The Journal of pharmacology and experimental therapeutics20030201
Title: HMG-CoA reductase inhibitor ameliorates diabetic nephropathy by its pleiotropic effects in rats.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20030201
Title: HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology20030201
Title: [Rhabdomyolysis following cerivastatin monotherapy--implications for therapy with HMG-CoA reductase inhibitors].
Journal: Der Nervenarzt20030201
Title: [Cerivastatin and the PRINCESS study: reflexions after 1 year].
Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology20030201
Title: Effect of nifedipine and cerivastatin on coronary endothelial function in patients with coronary artery disease: the ENCORE I Study (Evaluation of Nifedipine and Cerivastatin On Recovery of coronary Endothelial function).
Journal: Circulation20030128
Title: Myoglobinuria and COX deficiency in a patient taking cerivastatin and gemfibrozil.
Journal: Neurology20030114
Title: Protective effect of HMG-CoA reductase inhibitor on experimental renal ischemia-reperfusion injury.
Journal: American journal of nephrology20030101
Title: Effects of cerivastatin on vascularized allogenic bone transplantation in rats treated with cyclosporine A.
Journal: Calcified tissue international20030101
Title: Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.
Journal: Archives of biochemistry and biophysics20030101
Title: Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA.
Journal: Kidney international20030101
Title: The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research20030101
Title: HMG-CoA reductase inhibitor has protective effects against stroke events in stroke-prone spontaneously hypertensive rats.
Journal: Stroke20030101
Title: Cerivastatin and atorvastatin inhibit IL-3-dependent differentiation and IgE-mediated histamine release in human basophils and downmodulate expression of the basophil-activation antigen CD203c/E-NPP3.
Journal: Journal of leukocyte biology20030101
Title: Issues that led to the withdrawal of cerivastatin.
Journal: Current atherosclerosis reports20030101
Title: Cerivastatin: a cellular and molecular drug for the future?
Journal: Cellular and molecular life sciences : CMLS20030101
Title: [Information regarding adverse drug effects and treatment indications ('package inserts') exemplified by cervistatin (Lipobay)].
Journal: Wiener medizinische Wochenschrift (1946)20030101
Title: Contribution of Rho A and Rho kinase to platelet-derived growth factor-BB-induced proliferation of vascular smooth muscle cells.
Journal: Journal of atherosclerosis and thrombosis20030101
Title: [Adverse effects of statins].
Journal: Therapie20030101
Title: [Clinico-pharmacologic explanation models of cerivastatin associated rhabdomyolysis].
Journal: Wiener medizinische Wochenschrift (1946)20030101
Title: Cerivastatin ameliorates high insulin-enhanced neutrophil-endothelial cell adhesion and endothelial intercellular adhesion molecule-1 expression by inhibiting mitogen-activated protein kinase activation.
Journal: Journal of diabetes and its complications20030101
Title: Interaction between fibrates and statins--metabolic interactions with gemfibrozil.
Journal: Drug metabolism and drug interactions20030101
Title: Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials.
Journal: BMC family practice20030101
Title: Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells.
Journal: Circulation20021203
Title: Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20021201
Title: Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals20021201
Title: Statin inhibits leukocyte-endothelial interaction and prevents neuronal death induced by ischemia-reperfusion injury in the rat retina.
Journal: Archives of ophthalmology (Chicago, Ill. : 1960)20021201
Title: Limited adherence to safety instructions in drug leaflets.
Journal: British journal of clinical pharmacology20021201
Title: Gemfibrozil greatly increases plasma concentrations of cerivastatin.
Journal: Clinical pharmacology and therapeutics20021201
Title: Cerivastatin, a HMG-CoA reductase inhibitor, reduces plasminogen activator inhibitor-1 (PAI-1) expression in endothelial cells by down-regulation of cellular signaling and the inhibition of PAI-1 promoter activity.
Journal: Japanese journal of pharmacology20021201
Title: High rates of adverse effects and patient unawareness of withdrawn lipid-lowering drug combination in a public hospital clinic.
Journal: Pharmacoepidemiology and drug safety20021201
Title: Cerivastatin potentiates nitric oxide release and enos expression through inhibition of isoprenoids synthesis.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20021201
Title: Side effects of statins--prevalence, relevance, consequences.
Journal: Wiener klinische Wochenschrift20021130
Title: Inhibition of migration of human glioblastoma cells by cerivastatin in association with focal adhesion kinase (FAK).
Journal: Cancer letters20021128
Title: Cerivastatin enhances the cytotoxicity of 5-fluorouracil on chemosensitive and resistant colorectal cancer cell lines.
Journal: FEBS letters20021120
Title: Impact of hydroxymethylglutaryl coenzyme a reductase inhibition on left ventricular remodeling after myocardial infarction: an experimental serial cardiac magnetic resonance imaging study.
Journal: Journal of the American College of Cardiology20021106
Title: Regulation of interleukin-8 expression by HMG-CoA reductase inhibitors in human vascular smooth muscle cells.
Journal: Atherosclerosis20021101
Title: Cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, inhibits cardiac myocyte hypertrophy induced by endothelin.
Journal: European journal of pharmacology20021025
Title: TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS.
Journal: Cardiovascular research20021001
Title: Anti-inflammatory effect of cerivastatin in vascular injury independent of serum cholesterol and blood pressure lowering effects in mouse model.
Journal: Chinese journal of traumatology = Zhonghua chuang shang za zhi20021001
Title: Rhabdomyolysis with concurrent atorvastatin and diltiazem.
Journal: The Annals of pharmacotherapy20021001
Title: Additive effect of plant sterol-ester margarine and cerivastatin in lowering low-density lipoprotein cholesterol in primary hypercholesterolemia.
Journal: The American journal of cardiology20021001
Title: Rhabdomyolysis and cerivastatin: was it a problem of dose?
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne20021001
Title: Direct in vivo evidence of a vascular statin: a single dose of cerivastatin rapidly increases vascular endothelial responsiveness in healthy normocholesterolaemic subjects.
Journal: British journal of clinical pharmacology20021001
Title: Treatment with cerivastatin in primary mixed hyperlipidemia induces changes in platelet aggregation and coagulation system components.
Journal: International journal of hematology20021001
Title: [Surrogate end points as a clinical and public health problem. The cerivastatin case].
Journal: Medicina clinica20020907
Title: Postischemic acute renal failure is reduced by short-term statin treatment in a rat model.
Journal: Journal of the American Society of Nephrology : JASN20020901
Title: Cerivastatin and gemfibrozil-induced cardiac rhabdomyolysis.
Journal: The American journal of forensic medicine and pathology20020901
Title: ACC/AHA/NHLBI Clinical Advisory on the Use and Safety of Statins.
Journal: Stroke20020901
Title: Controversy surrounding the safety of cerivastatin.
Journal: Expert opinion on drug safety20020901
Title: Influence of lipid-lowering therapy on the progression of coronary artery calcification: a prospective evaluation.
Journal: Circulation20020827
Title: ACC/AHA/NHLBI Clinical Advisory on the Use and Safety of Statins.
Journal: Circulation20020820
Title: Contacting patients of a Pakistani hospital about a drug recall.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists20020815
Title: ACC/AHA/NHLBI clinical advisory on the use and safety of statins.
Journal: Journal of the American College of Cardiology20020807
Title: Mechanisms of inhibitory effects of cerivastatin on rat vascular smooth muscle cell growth.
Journal: Journal of cardiovascular pharmacology20020801
Title: Cerivastatin improves insulin sensitivity and insulin secretion in early-state obese type 2 diabetes.
Journal: Diabetes20020801
Title: The use of statins after solid organ transplantation.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20020801
Title: Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice.
Journal: Circulation research20020726
Title: Severe rhabdomyolysis related to cerivastatin without gemfibrozil.
Journal: Annals of internal medicine20020702
Title: Rho/Rho-kinase is involved in the synthesis of tissue factor in human monocytes.
Journal: Atherosclerosis20020701
Title: Rhabdomyolysis-related renal tubular damage studied by proton nuclear magnetic resonance spectroscopy of urine.
Journal: Clinical chemistry20020701
Title: A 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, cerivastatin, suppresses production of matrix metalloproteinase-9 in human abdominal aortic aneurysm wall.
Journal: Journal of vascular surgery20020701
Title: Effects of cerivastatin and parathyroid hormone on the lumbar vertebra of aging male Sprague-Dawley rats.
Journal: Bone20020701
Title: Simvastatin reduces expression of cytokines interleukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholesterolemic patients.
Journal: Arteriosclerosis, thrombosis, and vascular biology20020701
Title: Intensification of free radical oxidation of low-density lipoproteins in the plasma of patients with ischemic heart disease receiving beta-hydroxy-beta-methylglutaryl-coenzyme A reductase inhibitor cerivastatin and inhibition of low-density lipoprotein peroxidation with antioxidant probucol.
Journal: Bulletin of experimental biology and medicine20020701
Title: Inhibition of Rho/Rho-kinase signaling downregulates plasminogen activator inhibitor-1 synthesis in cultured human monocytes.
Journal: Biochimica et biophysica acta20020612
Title: Statin enhances cytokine-mediated induction of nitric oxide synthesis in vascular smooth muscle cells.
Journal: Cardiovascular research20020601
Title: Cerivastatin and the dissemination of adverse event information.
Journal: The Annals of pharmacotherapy20020601
Title: Rhabdomyolysis from high-dose cerivastatin therapy.
Journal: The Annals of pharmacotherapy20020601
Title: Implementation of a therapeutic-interchange clinic for HMG-CoA reductase inhibitors.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists20020601
Title: Rhabdomyolysis associated with cerivastatin: six cases within 3 months at one hospital.
Journal: Pharmacotherapy20020601
Title: Reversal of thrombin-induced deactivation of CD39/ATPDase in endothelial cells by HMG-CoA reductase inhibition: effects on Rho-GTPase and adenosine nucleotide metabolism.
Journal: Arteriosclerosis, thrombosis, and vascular biology20020601
Title: Rho-GTPase-dependent platelet-neutrophil interaction affected by HMG-CoA reductase inhibition with altered adenosine nucleotide release and function.
Journal: Arteriosclerosis, thrombosis, and vascular biology20020601
Title: Effects of cerivastatin on vascular function of human radial and left internal thoracic arteries.
Journal: The Annals of thoracic surgery20020601
Title: A randomized, double-blind comparison of cerivastatin and lovastatin for treatment of primary hypercholesterolemia.
Journal: Zhonghua yi xue za zhi = Chinese medical journal; Free China ed20020601
Title: [Rhabdomyolisis associated with cerivastatin and cyclosporine combination therapy].
Journal: Medicina clinica20020518
Title: [Acute cholestatic hepatitis induced by cerivastatin].
Journal: Medicina clinica20020518
Title: Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization.
Journal: Drug metabolism and disposition: the biological fate of chemicals20020501
Title: Effect of cerivastatin on proteinuria and urinary podocytes in patients with chronic glomerulonephritis.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20020501
Title: Statins and the assessment of endothelial function.
Journal: Journal of internal medicine20020501
Title: Issues concerning the monitoring of statin therapy in hypercholesterolemic subjects with high plasma lipoprotein(a) levels.
Journal: Lipids20020501
Title: Statins and muscles: what price glory?
Journal: Joint, bone, spine : revue du rhumatisme20020501
Title: Interaction between blood pressure, lipoproteins, angiotensin, and vascular disease.
Journal: Current hypertension reports20020401
Title: HMG-CoA reductase inhibitor cerivastatin prolonged rat cardiac allograft survival by blocking intercellular signals.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation20020401
Title: Severe rhabdomyolysis and cerivastatin-gemfibrozil combination therapy.
Journal: The Annals of pharmacotherapy20020401
Title: Cerivastatin-induced rhabdomyolysis: 11 case reports.
Journal: Pharmacotherapy20020401
Title: Cerivastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase, inhibits endothelial cell proliferation induced by angiogenic factors in vitro and angiogenesis in in vivo models.
Journal: Arteriosclerosis, thrombosis, and vascular biology20020401
Title: [Myotoxicity and rhabdomyolisis due to statins].
Journal: Nederlands tijdschrift voor geneeskunde20020302
Title: Statin stories.
Journal: Diabetes, obesity & metabolism20020301
Title: Rhabdomyolysis associated with cerivastatin plus gemfibrozil combined regimen.
Journal: The British journal of general practice : the journal of the Royal College of General Practitioners20020301
Title: HMG-CoA reductase inhibitors reduce interleukin-6 synthesis in human vascular smooth muscle cells.
Journal: Cardiovascular drugs and therapy20020301
Title: Increased nitric oxide bioavailability in endothelial cells contributes to the pleiotropic effect of cerivastatin.
Journal: Circulation20020226
Title: Cerivastatin and reports of fatal rhabdomyolysis.
Journal: The New England journal of medicine20020214
Title: Statins have biphasic effects on angiogenesis.
Journal: Circulation20020212
Title: Why some patients respond poorly to statins and how this might be remedied.
Journal: European heart journal20020201
Title: Lipid-lowering drugs (statins), cholesterol, and coenzyme Q10. The Baycol case--a modern Pandora's box.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie20020201
Title: Risperidone and severe cerivastatin-induced rhabdomyolysis.
Journal: Journal of internal medicine20020201
Title: Apolipoprotein E alleles, dyslipemia and kidney transplantation.
Journal: Transplantation proceedings20020201
Title: Effects of cerivastatin in dyslipemia and other cardiovascular risk factors after renal transplantation.
Journal: Transplantation proceedings20020201
Title: Cholesterol drugs: very safe and highly beneficial.
Journal: The Johns Hopkins medical letter health after 5020020201
Title: Cerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days.
Journal: Circulation20020129
Title: Cerivastatin and endothelial function in elderly patients with diabetes mellitus.
Journal: Circulation20020129
Title: Bayer faces Swiss criminal probe over cerivastatin.
Journal: BMJ (Clinical research ed.)20020119
Title: Kinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase.
Journal: FEBS letters20020116
Title: Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.
Journal: Biochemical and biophysical research communications20020111
Title: Both cerivastatin and fenofibrate improve arterial vasoreactivity in patients with combined hyperlipidaemia.
Journal: Journal of internal medicine20020101
Title: [Unexpected consequences of an expected adverse effect of cerivastatine].
Journal: La Revue de medecine interne20020101
Title: [Attitude to and marketing of cerivastatin].
Journal: Acta medica Austriaca20020101
Title: [Rhabdomyolysis, acute renal failure and use of cerivastatin combined with gemfibrozil. New evidence].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia20020101
Title: Cerivastatin modulates plasma paraoxonase/arylesterase activity and oxidant-antioxidant balance in the rat.
Journal: Polish journal of pharmacology20020101
Title: [Myopathy due to statins, a dose-dependent effect, and of what kind?].
Journal: Atencion primaria20020101
Title: Cerivastatin induces rhabdomyolysis and acute renal failure.
Journal: Nephron20020101
Title: HMG CoA reductase-inhibitor-related myopathy and the influence of drug interactions.
Journal: Internal medicine journal20020101
Title: Rhabdomyolysis from the combination of a statin and gemfibrozil: an uncommon but serious adverse reaction.
Journal: WMJ : official publication of the State Medical Society of Wisconsin20020101
Title: A multidisciplinary program for achieving lipid goals in chronic hemodialysis patients.
Journal: BMC nephrology20020101
Title: [Myopathy with rhabdomyolysis as an adverse effect of simultaneous treatment with cerivastatin and gemfibrozil].
Journal: Lijecnicki vjesnik20020101
Title: HMG-CoA reductase inhibitors reduce adhesion of human monocytes to endothelial cells.
Journal: Biochemical and biophysical research communications20011214
Title: [Myotoxicity and rhabdomyolisis due to statins].
Journal: Nederlands tijdschrift voor geneeskunde20011208
Title: Massive rhabdomyolysis and life threatening hyperkalaemia in a patient with the combination of cerivastatin and gemfibrozil.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20011201
Title: Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in vascular smooth muscle cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology20011201
Title: Top ten health stories of 2001.
Journal: Harvard health letter20011201
Title: The withdrawal of Baycol (cerivastatin).
Journal: Adverse drug reactions and toxicological reviews20011201
Title: [Rhabdomyolysis associated with combined treatment of cerivastatin and gemfibrozil].
Journal: Revista clinica espanola20011201
Title: Effect of diet and treatment with statins on platelet-dependent thrombin generation in hypercholesterolemic subjects.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD20011201
Title: Other reports of cerivastatin-induced rhabdomyolysis.
Journal: Archives of internal medicine20011126
Title: Another report of acute rhabdomyolysis following cerivastatin monotherapy.
Journal: Archives of internal medicine20011126
Title: Case reports of rhabdomyolysis associated with cerivastatin therapy.
Journal: Archives of internal medicine20011126
Title: Upregulation of CD40 and CD40 ligand (CD154) in patients with moderate hypercholesterolemia.
Journal: Circulation20011113
Title: Statin-associated myopathy.
Journal: The Medical journal of Australia20011105
Title: Endothelial nitric oxide synthase is essential for the HMG-CoA reductase inhibitor cerivastatin to promote collateral growth in response to ischemia.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20011101
Title: By the way, doctor...I read about Baycol, the cholesterol-lowering drug being taken off the market because it caused fatal muscle damage. I don't take it, but I do take another statin. Should I be worried?
Journal: Harvard health letter20011101
Title: [Cerivastatin. Which lessons for clinical practice?].
Journal: Recenti progressi in medicina20011101
Title: [We, the Italian physicians, and statins].
Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology20011101
Title: Learning from the cerivastatin experience.
Journal: Lancet (London, England)20011027
Title: [Rhabdomyolysis induced by cerivastatin].
Journal: Atencion primaria20011015
Title: [Cerivastatin and gemfibrozil: a dangerous combination].
Journal: Atencion primaria20011015
Title: Regulation of endothelial nitric oxide synthase expression in the vascular wall and in mononuclear cells from hypercholesterolemic rabbits.
Journal: Circulation20011009
Title: Bayer lapse exposes pharma's vulnerability.
Journal: Nature biotechnology20011001
Title: Baycol: take-home messages about medications.
Journal: Harvard heart letter : from Harvard Medical School20011001
Title: Managed care trends in statin usage.
Journal: Managed care (Langhorne, Pa.)20011001
Title: [Useful knowledge and demonstrated competence?].
Journal: Medizinische Monatsschrift fur Pharmazeuten20011001
Title: Substituting for cerivastatin (Baycol).
Journal: The Medical letter on drugs and therapeutics20010917
Title: [Severe rhabdomyolysis associated with cerivastatin and gemfibrozil].
Journal: Medicina clinica20010915
Title: Comparison of the efficacy of atorvastatin versus cerivastatin in primary hypercholesterolemia.
Journal: The American journal of cardiology20010915
Title: Cerivastatin withdrawn from market.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists20010915
Title: Bayer pulls cerivastatin (Baycol) from market.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne20010904
Title: Rest easy, statin users. Benefits dwarf risks for these cholesterol drugs.
Journal: U.S. news & world report20010903
Title: Induction of apoptosis and inhibition of migration of inflammatory and vascular wall cells by cerivastatin.
Journal: Atherosclerosis20010901
Title: Lipid-lowering efficacy, safety, and costs of a large-scale therapeutic statin formulary conversion program.
Journal: Pharmacotherapy20010901
Title: [Cholesterin synthase inhibition and atherosclerosis].
Journal: Der Internist20010901
Title: Cerivastatin and gemfibrozil-associated rhabdomyolysis.
Journal: The Annals of pharmacotherapy20010901
Title: Cerivastatin versus branded pravastatin in the treatment of primary hypercholesterolemia in primary care practice in Canada: a one-year, open-label, randomized, comparative study of efficacy, safety, and cost-effectiveness.
Journal: Clinical therapeutics20010901
Title: Long-term efficacy and safety of cerivastatin 0.8 mg in patients with primary hypercholesterolemia.
Journal: Clinical cardiology20010901
Title: Statin safety.
Journal: Nursing standard (Royal College of Nursing (Great Britain) : 1987)20010901
Title: Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis.
Journal: Circulation research20010831
Title: Improvement of left ventricular remodeling and function by hydroxymethylglutaryl coenzyme a reductase inhibition with cerivastatin in rats with heart failure after myocardial infarction.
Journal: Circulation20010828
Title: Bayer faces potential fine over cholesterol lowering drug.
Journal: BMJ (Clinical research ed.)20010825
Title: [After recall of cerivastatin. How safe are statins in reality? (interview by Dr. Dirk Einecke)].
Journal: MMW Fortschritte der Medizin20010823
Title: Baycol withdrawn from market.
Journal: Circulation20010821
Title: Bayer decides to withdraw cholesterol lowering drug.
Journal: BMJ (Clinical research ed.)20010818
Title: In vitro antitumor activity of cerivastatin, a novel and potent HMG-CoA reductase inhibitor.
Journal: FEBS letters20010817
Title: Cerivastatin-induced rhabdomyolysis in a renal transplant on cyclosporin.
Journal: Transplantation20010815
Title: Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro study.
Journal: Carcinogenesis20010801
Title: Tacrolimus/cerivastatin interaction study in liver transplant recipients.
Journal: British journal of clinical pharmacology20010801
Title: Casebook: jaundice.
Journal: The Practitioner20010801
Title: [Fatal rhabdomyolysis caused by cerivastatin].
Journal: Revue medicale de Liege20010801
Title: Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins).
Journal: European journal of clinical pharmacology20010801
Title: Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor.
Journal: Circulation20010731
Title: Cerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days.
Journal: Circulation20010724
Title: Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20010701
Title: Hmg-CoA reductase inhibitor modulates monocyte-endothelial cell interaction under physiological flow conditions in vitro: involvement of Rho GTPase-dependent mechanism.
Journal: Arteriosclerosis, thrombosis, and vascular biology20010701
Title: Short-term effects of statin therapy in patients with hyperlipoproteinemia after liver transplantation: results of a randomized cross-over trial.
Journal: Journal of hepatology20010701
Title: Rhabdomyolysis due to cerivastatin monotherapy.
Journal: The American journal of medicine20010615
Title: Normocholesterolaemic dysslipidaemia: is there a role for fibrates?
Journal: The Medical journal of Australia20010604
Title: Effect of statin versus fibrate on postprandial endothelial dysfunction: role of remnant-like particles.
Journal: Cardiovascular research20010601
Title: Combination therapy with cerivastatin and gemfibrozil causing rhabdomyolysis: is the interaction predictable?
Journal: The American journal of medicine20010601
Title: Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I.
Journal: The Journal of clinical investigation20010601
Title: Modulating angiotensin II-induced inflammation by HMG Co-A reductase inhibition.
Journal: American journal of hypertension20010601
Title: The pharmacokinetics of cerivastatin in patients on chronic hemodialysis.
Journal: International journal of clinical pharmacology and therapeutics20010501
Title: Statin induced myopathy does not show up in MIBI scintigraphy.
Journal: Nuclear medicine communications20010501
Title: Statins and bone formation.
Journal: Current pharmaceutical design20010501
Title: A cost-effectiveness model of alternative statins to achieve target LDL-cholesterol levels.
Journal: International journal of clinical practice20010501
Title: Inhibition of endothelial cell migration by cerivastatin, an HMG-CoA reductase inhibitor: contribution to its anti-angiogenic effect.
Journal: FEBS letters20010427
Title: Rhabdomyolysis after cerivastatin-gemfibrozil therapy in an HIV-infected patient with protease inhibitor-related hyperlipidemia.
Journal: AIDS (London, England)20010413
Title: Safety of statins (hydroxymethyl glutaryl coenzyme a reductase inhibitors): different mechanisms of metabolism and drug transport may have clinical relevance.
Journal: Archives of internal medicine20010409
Title: Rapid improvement of nitric oxide bioavailability after lipid-lowering therapy with cerivastatin within two weeks.
Journal: Journal of the American College of Cardiology20010401
Title: The effects of the statins lovastatin and cerivastatin on signalling by the prostanoid IP-receptor.
Journal: British journal of pharmacology20010401
Title: [Rhabdomyolysis complicated with acute renal insufficiency in a patient treated with gemfibrozil and cerivastatin].
Journal: Revista clinica espanola20010401
Title: Acute rhabdomyolysis associated with cerivastatin therapy.
Journal: Archives of internal medicine20010326
Title: Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia.
Journal: Circulation20010306
Title: Cerivastatin prevents tumor necrosis factor-alpha-induced downregulation of endothelial nitric oxide synthase: role of endothelial cytosolic proteins.
Journal: Atherosclerosis20010301
Title: Statin therapy--what now?
Journal: Drug and therapeutics bulletin20010301
Title: [Characteristics of a statine of the most recent generation].
Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology20010301
Title: Influence of gender on the pharmacokinetics, safety, and tolerability of cerivastatin in healthy adults.
Journal: European journal of clinical pharmacology20010301
Title: [Ongoing clinical trials by vascular statin, cerivastatin].
Journal: Nihon rinsho. Japanese journal of clinical medicine20010301
Title: [Cerivastatin].
Journal: Nihon rinsho. Japanese journal of clinical medicine20010301
Title: Comparative effects of cerivastatin and fenofibrate on the atherogenic lipoprotein phenotype in proteinuric renal disease.
Journal: Journal of the American Society of Nephrology : JASN20010201
Title: An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro.
Journal: Circulation20010116
Title: Effective use of statins to prevent coronary heart disease.
Journal: American family physician20010115
Title: Statin trials in progress: unanswered questions.
Journal: Current atherosclerosis reports20010101
Title: New statins and new doses of older statins.
Journal: Current atherosclerosis reports20010101
Title: Statins in children: what do we know and what do we need to do?
Journal: Current atherosclerosis reports20010101
Title: The CHORUS (Cerivastatin in Heart Outcomes in Renal Disease: Understanding Survival) protocol: a double-blind, placebo-controlled trial in patients with esrd.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation20010101
Title: Efficacy and drug interactions of the new HMG-CoA reductase inhibitors cerivastatin and atorvastatin in CsA-treated renal transplant recipients.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20010101
Title: Cerivastatin-induced rhabdomyolisis in a patient with diabetic nephropathy.
Journal: American journal of nephrology20010101
Title: Newer HMG-CoA reductase inhibitor (statin) therapies.
Journal: Clinical cardiology20010101
Title: Severe rhabdomyolysis associated with the cerivastin-gemfibrozil combination therapy: report of a case.
Journal: Texas Heart Institute journal20010101
Title: Hypertriglyceridemia: a review of clinical relevance and treatment options: focus on cerivastatin.
Journal: Current medical research and opinion20010101
Title: Synthetic statins: more data on newer lipid-lowering agents.
Journal: Current medical research and opinion20010101
Title: Cerivastatin induces carotid artery plaque stabilization independently of cholesterol lowering in patients with hypercholesterolaemia.
Journal: The Journal of international medical research20010101
Title: Clinical-pharmacological strategies to assess drug interaction potential during drug development.
Journal: Drug safety20010101
Title: Changes in bone biochemical markers after high-dose cerivastatin treatment in a woman with osteogenesis imperfecta.
Journal: Journal of bone and mineral metabolism20010101
Title: The evaluation of pharmacologic therapy in humans: a brief summary of the drug evaluation process and guidelines for clinical trials as they related to women.
Journal: The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia20010101
Title: [Rhabdomyolysis and anuric kidney failure induced by the treatment with a gemfibrozil-cerivastatin combination].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia20010101
Title: [Cerivastatin and acute kidney failure caused by rhabdomyolysis].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia20010101
Title: Effect of cerivastatin on urinary albumin excretion and plasma endothelin-1 concentrations in type 2 diabetes patients with microalbuminuria and dyslipidemia.
Journal: American journal of nephrology20010101
Title: [Massive rhabdomyolysis associated with the use of cerivastatin monotherapy].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia20010101
Title: Bayer voluntarily withdraws Baycol.
Journal: AWHONN lifelines20010101
Title: A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy--a case report.
Journal: Angiology20000801
Title: Rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy.
Journal: The American journal of cardiology19990401
