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144-21-8,MFCD00072429
Catalog No.:AA001IOL

144-21-8 | Sodium methylarsonate

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500mg
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1g
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$64.00   $45.00
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5g
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$115.00   $80.00
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25g
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100g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001IOL
Chemical Name:
Sodium methylarsonate
CAS Number:
144-21-8
Molecular Formula:
CH3AsNa2O3
Molecular Weight:
183.9339
MDL Number:
MFCD00072429
SMILES:
[O-][As](=O)(C)[O-].[Na+].[Na+]
UN Number:
3082
Properties
Computed Properties
 
Complexity:
49.8  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
3  

Literature

Title: [Changes in mRNA expression of p53 and related downstream genes in peripheral blood lymphocytes in workers occupationally exposed to arsenic].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20151201

Title: Positive selection of AS3MT to arsenic water in Andean populations.

Journal: Mutation research 20151001

Title: Influence of the level of arsenic (As) exposure and the presence of T860C polymorphism in human As urinary metabolic profile.

Journal: Human & experimental toxicology 20150201

Title: Arsenic exposure disrupts the normal function of the FA/BRCA repair pathway.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20141101

Title: A novel pathway for arsenic elimination: human multidrug resistance protein 4 (MRP4/ABCC4) mediates cellular export of dimethylarsinic acid (DMAV) and the diglutathione conjugate of monomethylarsonous acid (MMAIII).

Journal: Molecular pharmacology 20140801

Title: Methylarsonous acid causes oxidative DNA damage in cells independent of the ability to biomethylate inorganic arsenic.

Journal: Archives of toxicology 20140201

Title: Health effects and arsenic species in urine of copper smelter workers.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20140101

Title: SLCO1B1 variants and urine arsenic metabolites in the Strong Heart Family Study.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131101

Title: N-6-adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms and arsenic methylation in Andean women.

Journal: Environmental health perspectives 20130701

Title: Differential toxicity and gene expression in Caco-2 cells exposed to arsenic species.

Journal: Toxicology letters 20130327

Title: Methylation of arsenic by recombinant human wild-type arsenic (+3 oxidation state) methyltransferase and its methionine 287 threonine (M287T) polymorph: Role of glutathione.

Journal: Toxicology and applied pharmacology 20121001

Title: Binational arsenic exposure survey: methodology and estimated arsenic intake from drinking water and urinary arsenic concentrations.

Journal: International journal of environmental research and public health 20120401

Title: Methylated arsenic species in plants originate from soil microorganisms.

Journal: The New phytologist 20120201

Title: Indigenous American ancestry is associated with arsenic methylation efficiency in an admixed population of northwest Mexico.

Journal: Journal of toxicology and environmental health. Part A 20120101

Title: The relationship between obesity, insulin and arsenic methylation capability in Taiwan adolescents.

Journal: The Science of the total environment 20120101

Title: Non-chromatographic screening procedure for arsenic speciation analysis in fish-based baby foods by using electrothermal atomic absorption spectrometry.

Journal: Analytica chimica acta 20110805

Title: Metabolites of arsenic and increased DNA damage of p53 gene in arsenic plant workers.

Journal: Toxicology and applied pharmacology 20110701

Title: Exposure to polycyclic aromatic hydrocarbons, arsenic and environmental tobacco smoke, nutrient intake, and oxidative stress in Japanese preschool children.

Journal: The Science of the total environment 20110701

Title: Good outcomes despite high urinary arsenic concentrations from overdose with crabgrass killer.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20110601

Title: A pathway-based analysis of urinary arsenic metabolites and skin lesions.

Journal: American journal of epidemiology 20110401

Title: Uptake of methylated arsenic by a polymeric adsorbent: process performance and adsorption chemistry.

Journal: Water research 20110301

Title: Inadvertent poisoning of seven teenagers with monosodium methanearsonate.

Journal: Clinical toxicology (Philadelphia, Pa.) 20110301

Title: Arsenic methylation efficiency increases during the first trimester of pregnancy independent of folate status.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20110201

Title: Gene polymorphisms of glutathione S-transferase omega 1 and 2, urinary arsenic methylation profile and urothelial carcinoma.

Journal: The Science of the total environment 20110101

Title: Association of genetic variation in cystathionine-beta-synthase and arsenic metabolism.

Journal: Environmental research 20100801

Title: Arsenic metabolism by human gut microbiota upon in vitro digestion of contaminated soils.

Journal: Environmental health perspectives 20100701

Title: Impact of smoking and chewing tobacco on arsenic-induced skin lesions.

Journal: Environmental health perspectives 20100401

Title: Characterization of the intestinal absorption of arsenate, monomethylarsonic acid, and dimethylarsinic acid using the Caco-2 cell line.

Journal: Chemical research in toxicology 20100315

Title: Trivalent arsenicals and glucose use different translocation pathways in mammalian GLUT1.

Journal: Metallomics : integrated biometal science 20100301

Title: Changes in urinary arsenic methylation profiles in a 15-year interval after cessation of arsenic ingestion in southwest Taiwan.

Journal: Environmental health perspectives 20091201

Title: Influence of cobalamin on arsenic metabolism in Bangladesh.

Journal: Environmental health perspectives 20091101

Title: Exposure to monomethylarsonous acid (MMA(III)) leads to altered selenoprotein synthesis in a primary human lung cell model.

Journal: Toxicology and applied pharmacology 20090901

Title: Electrospray ionization tandem mass spectrometric determination of monomethylarsonic acid and dimethylarsinic acid after adduct formation with citric acid.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090901

Title: Comparison of sensitivity to arsenic compounds between a Bhas 42 cell transformation assay and a BALB/c 3T3 cell transformation assay.

Journal: Mutation research 20090430

Title: Urinary arsenic methylation capability and carotid atherosclerosis risk in subjects living in arsenicosis-hyperendemic areas in southwestern Taiwan.

Journal: The Science of the total environment 20090401

Title: Effects of monomethylarsonic and monomethylarsonous acid on evoked synaptic potentials in hippocampal slices of adult and young rats.

Journal: Toxicology and applied pharmacology 20090401

Title: Arsenic methylation capability, myeloperoxidase and sulfotransferase genetic polymorphisms, and the stage and grade of urothelial carcinoma.

Journal: Urologia internationalis 20090101

Title: Arsenic exposure, urinary arsenic speciation, and the incidence of urothelial carcinoma: a twelve-year follow-up study.

Journal: Cancer causes & control : CCC 20081001

Title: Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile.

Journal: Toxicology and applied pharmacology 20081001

Title: Development of mass spectrometric methods for detecting arsenic-glutathione complexes.

Journal: Journal of the American Society for Mass Spectrometry 20081001

Title: A new interface used to couple capillary electrophoresis with an inductively coupled plasma mass spectrometry for speciation analysis.

Journal: Electrophoresis 20080701

Title: Arsenic trioxide and auranofin inhibit selenoprotein synthesis: implications for chemotherapy for acute promyelocytic leukaemia.

Journal: British journal of pharmacology 20080701

Title: Quantitative arsenic speciation in two species of earthworms from a former mine site.

Journal: Journal of environmental monitoring : JEM 20080601

Title: Non-chromatographic speciation of toxic arsenic in vegetables by hydride generation-atomic fluorescence spectrometry after ultrasound-assisted extraction.

Journal: Talanta 20080515

Title: Mechanisms of photocatalytical degradation of monomethylarsonic and dimethylarsinic acids using nanocrystalline titanium dioxide.

Journal: Environmental science & technology 20080401

Title: Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity.

Journal: Toxicology and applied pharmacology 20071201

Title: Impact of arsenic in foodstuffs on the people living in the arsenic-affected areas of West Bengal, India.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20071001

Title: Arsenic-induced bladder cancer in an animal model.

Journal: Toxicology and applied pharmacology 20070801

Title: Adsorption and photocatalyzed oxidation of methylated arsenic species in TiO2 suspensions.

Journal: Environmental science & technology 20070801

Title: Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid.

Journal: Environmental health perspectives 20070501

Title: Arsenic methylation, GSTT1, GSTM1, GSTP1 polymorphisms, and skin lesions.

Journal: Environmental health perspectives 20070301

Title: Arsenic methylation capability and hypertension risk in subjects living in arseniasis-hyperendemic areas in southwestern Taiwan.

Journal: Toxicology and applied pharmacology 20070115

Title: Environmental Arsenic Exposure and Urinary 8-OHdG in Arizona and Sonora.

Journal: Clinical toxicology (Philadelphia, Pa.) 20070101

Title: Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid.

Journal: Biochemical and biophysical research communications 20061215

Title: Effect of plasma homocysteine level and urinary monomethylarsonic acid on the risk of arsenic-associated carotid atherosclerosis.

Journal: Toxicology and applied pharmacology 20061001

Title: Effects of arsenic exposure among semiconductor workers: a cautionary note on urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine.

Journal: Free radical biology & medicine 20060401

Title: Methylarsonous acid transport by aquaglyceroporins.

Journal: Environmental health perspectives 20060401

Title: Metabolic profile in workers occupationally exposed to arsenic: role of GST polymorphisms.

Journal: Journal of occupational and environmental medicine 20060301

Title: A comparative study of the sub-chronic toxic effects of three organic arsenical compounds on the urothelium in F344 rats; gender-based differences in response.

Journal: Toxicology and applied pharmacology 20060201

Title: Effect of monosodium methanarsonate application on cuticle wax content of cocklebur and cotton plants.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20060101

Title: Folate, homocysteine, and arsenic metabolism in arsenic-exposed individuals in Bangladesh.

Journal: Environmental health perspectives 20051201

Title: Role of the alkali labile sites, reactive oxygen species and antioxidants in DNA damage induced by methylated trivalent metabolites of inorganic arsenic.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20051001

Title: Preventive mechanism of cellular glutathione in monomethylarsonic acid-induced cytolethality.

Journal: Toxicology and applied pharmacology 20050801

Title: Assessing interactions of multiple agrichemicals by using bacterial assemblages in a wetland mesocosm system.

Journal: International journal of environmental research and public health 20050801

Title: Response of multiple seeded cocklebur and other cocklebur types to herbicide treatment.

Journal: Pest management science 20050701

Title: Characterization of the monomethylarsonate reductase and dehydroascorbate reductase activities of Omega class glutathione transferase variants: implications for arsenic metabolism and the age-at-onset of Alzheimer's and Parkinson's diseases.

Journal: Pharmacogenetics and genomics 20050701

Title: Growth inhibition as indicator of stress because of atrazine following multiple toxicant exposure of the freshwater macrophyte, Juncus effusus L.

Journal: Environmental toxicology and chemistry 20050501

Title: Inorganic arsenic compounds and methylated metabolites induce morphological transformation in two-stage BALB/c 3T3 cell assay and inhibit metabolic cooperation in V79 cell assay.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050401

Title: Effects of long-term exposure of the red swamp crawfish Procambarus clarkii to a mixture of two herbicides, 2,4-dichlorophenoxyacetic acid and monosodium methanearsonate, and associated human health risks.

Journal: International journal of environmental research and public health 20040901

Title: A review of the enzymology of arsenic metabolism and a new potential role of hydrogen peroxide in the detoxication of the trivalent arsenic species.

Journal: Toxicology and applied pharmacology 20040801

Title: Biokinetics and subchronic toxic effects of oral arsenite, arsenate, monomethylarsonic acid, and dimethylarsinic acid in v-Ha-ras transgenic (Tg.AC) mice.

Journal: Environmental health perspectives 20040801

Title: MSMA resistance studies.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20040501

Title: Cellular glutathione prevents cytolethality of monomethylarsonic acid.

Journal: Toxicology and applied pharmacology 20040301

Title: Toxicity of a mixture of 2,4-dichlorophenoxyacetic acid and monosoduim methanearsonate to the red swamp crawfish, Procambarus clarkii.

Journal: International journal of environmental research and public health 20040301

Title: Determination of trivalent methylated arsenicals in rat urine by liquid chromatography-inductively coupled plasma mass spectrometry after solvent extraction.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040125

Title: Arsenic speciation in urine from acute promyelocytic leukemia patients undergoing arsenic trioxide treatment.

Journal: Chemical research in toxicology 20040101

Title: Induction of glutathione S-transferase placental form positive foci in liver and epithelial hyperplasia in urinary bladder, but no tumor development in male Fischer 344 rats treated with monomethylarsonic acid for 104 weeks.

Journal: Toxicology and applied pharmacology 20031215

Title: Polymorphisms in the human monomethylarsonic acid (MMA V) reductase/hGSTO1 gene and changes in urinary arsenic profiles.

Journal: Chemical research in toxicology 20031201

Title: Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice.

Journal: Toxicology letters 20031130

Title: Variability in human metabolism of arsenic.

Journal: Environmental research 20030601

Title: Arsenic methylation and bladder cancer risk in Taiwan.

Journal: Cancer causes & control : CCC 20030501

Title: Effect of selenite on the disposition of arsenate and arsenite in rats.

Journal: Toxicology 20030415

Title: Functional characterization of two variant human GSTO 1-1s (Ala140Asp and Thr217Asn).

Journal: Biochemical and biophysical research communications 20030207

Title: Arsenic speciation in the urine and hair of individuals exposed to airborne arsenic through coal-burning in Guizhou, PR China.

Journal: Toxicology letters 20030131

Title: Determination of arsenic metabolic complex excreted in human urine after administration of sodium 2,3-dimercapto-1-propane sulfonate.

Journal: Chemical research in toxicology 20021001

Title: Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S-transferase placental form positive foci: a possible reactive oxygen species mechanism.

Journal: International journal of cancer 20020710

Title: Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice.

Journal: Toxicology and applied pharmacology 20011215

Title: Human monomethylarsonic acid (MMA(V)) reductase is a member of the glutathione-S-transferase superfamily.

Journal: Chemical research in toxicology 20010801

Title: Monomethylarsonous acid (MMA(III)) and arsenite: LD(50) in hamsters and in vitro inhibition of pyruvate dehydrogenase.

Journal: Chemical research in toxicology 20010601

Title: Differential effects of trivalent and pentavalent arsenicals on cell proliferation and cytokine secretion in normal human epidermal keratinocytes.

Journal: Toxicology and applied pharmacology 20010501

Title: Enzymatic reduction of arsenic compounds in mammalian systems: the rate-limiting enzyme of rabbit liver arsenic biotransformation is MMA(V) reductase.

Journal: Chemical research in toxicology 19991201

Title: Enzymatic methylation of arsenic compounds. VII. Monomethylarsonous acid (MMAIII) is the substrate for MMA methyltransferase of rabbit liver and human hepatocytes.

Journal: Toxicology and applied pharmacology 19990701

Title: Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms.

Journal: Chemical research in toxicology 19980401

Title: Enzymatic methylation of arsenic compounds: assay, partial purification, and properties of arsenite methyltransferase and monomethylarsonic acid methyltransferase of rabbit liver.

Journal: Chemical research in toxicology 19951201

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