Home Fluorides 144089-97-4
144089-97-4,MFCD12912415
Catalog No.:AA00ASS8

144089-97-4 | 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)guanosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

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Purity
Availability
Price(USD)
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100mg
98%
in stock  
$51.00   $36.00
- +
250mg
98%
in stock  
$73.00   $51.00
- +
1g
98%
in stock  
$201.00   $141.00
- +
5g
98%
in stock  
$706.00   $494.00
- +
  • Technical Information
  • Properties
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ASS8
Chemical Name:
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)guanosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS Number:
144089-97-4
Molecular Formula:
C44H53FN7O8P
Molecular Weight:
857.9059
MDL Number:
MFCD12912415
SMILES:
N#CCCOP(N(C(C)C)C(C)C)OC1[C@@H](COC(c2ccc(cc2)OC)(c2ccc(cc2)OC)c2ccccc2)O[C@H](C1F)n1cnc2c1[nH]c(NC(=O)C(C)C)nc2=O
Properties
Computed Properties
 
Complexity:
1480  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
61  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
19  
Undefined Atom Stereocenter Count:
1  
XLogP3:
6.1  

Literature

Title: Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555.

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Tags:144089-97-4 Molecular Formula|144089-97-4 MDL|144089-97-4 SMILES|144089-97-4 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)guanosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]