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144409-98-3,MFCD00717583
Catalog No.:AA00AQ3P

144409-98-3 | AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT)

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Purity
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Price(USD)
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1mg
95%
1 week  
$368.00   $258.00
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  • Technical Information
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Technical Information
Catalog Number:
AA00AQ3P
Chemical Name:
AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT)
CAS Number:
144409-98-3
Molecular Formula:
C190H291N51O57S
Molecular Weight:
4233.7160
MDL Number:
MFCD00717583
SMILES:
NCCCCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)O)C(C)C)C(C)C)C(C)C)CCSC)CC(C)C)C(CC)C)C(CC)C)C)CCCCN)CC(=O)N)CO)C(C)C)CC(=O)O)CCC(=O)O)C)Cc1ccccc1)Cc1ccccc1)C(C)C)CC(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(C(C)C)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(Cc1nc[nH]c1)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(CC(=O)O)N)C)CCC(=O)O)Cc1ccccc1)CC(=O)O)CO)CCC(=O)O)CCCNC(=N)N)Cc1nc[nH]c1)CCC(=O)N
Properties
Computed Properties
 
Complexity:
10300  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
32  
Heavy Atom Count:
299  
Hydrogen Bond Acceptor Count:
64  
Hydrogen Bond Donor Count:
58  
Rotatable Bond Count:
143  
Undefined Atom Stereocenter Count:
3  
XLogP3:
-12.9  

Literature

Title: MacManus A, et, al. Enhancement of (45)Ca(2+) influx and voltage-dependent Ca(2+) channel activity by beta-amyloid-(1-40) in rat cortical synaptosomes and cultured cortical neurons. Modulation by the proinflammatory cytokine interleukin-1beta. J Biol Chem. 2000 Feb 18;275(7):4713-8.

Title: Miguel-Hidalgo JJ, et, al. Beta-amyloid(1-40)-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield. Acta Neuropathol. 1998 May;95(5):455-65.

Title: Prediger RD, et, al. Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response. Behav Brain Res. 2007 Feb 27;177(2):205-13.

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SDS
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Tags:144409-98-3 Molecular Formula|144409-98-3 MDL|144409-98-3 SMILES|144409-98-3 AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT)