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1445993-26-9,MFCD30377200
Catalog No.:AA001JQM

1445993-26-9 | Mivebresib

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$17.00   $12.00
- +
2mg
97%
in stock  
$29.00   $20.00
- +
5mg
97%
in stock  
$42.00   $30.00
- +
10mg
97%
in stock  
$64.00   $45.00
- +
25mg
97%
in stock  
$108.00   $76.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA001JQM
Chemical Name:
Mivebresib
CAS Number:
1445993-26-9
Molecular Formula:
C22H19F2N3O4S
Molecular Weight:
459.4658
MDL Number:
MFCD30377200
SMILES:
CCS(=O)(=O)Nc1ccc(c(c1)c1cn(C)c(=O)c2c1cc[nH]2)Oc1ccc(cc1F)F
Properties
Computed Properties
 
Complexity:
834  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.9  

Literature

Title: Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor.

Journal: Journal of medicinal chemistry 20171026

Title: EJ Faivre et al. Abstract 4694: ABBV-075, a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo

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SDS
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5868-54-2

5868-54-2
Tags:1445993-26-9 Molecular Formula|1445993-26-9 MDL|1445993-26-9 SMILES|1445993-26-9 Mivebresib
Catalog No.: AA001JQM
1445993-26-9,MFCD30377200
1445993-26-9 | Mivebresib
Pack Size： 1mg
Purity： 97%
in stock
$17.00 $12.00
Pack Size： 2mg
Purity： 97%
in stock
$29.00 $20.00
Pack Size： 5mg
Purity： 97%
in stock
$42.00 $30.00
Pack Size： 10mg
Purity： 97%
in stock
$64.00 $45.00
Pack Size： 25mg
Purity： 97%
in stock
$108.00 $76.00
Quantity
- +
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bulk Quotation Request
Technical Information
Catalog Number: AA001JQM
Chemical Name: Mivebresib
CAS Number: 1445993-26-9
Molecular Formula: C22H19F2N3O4S
Molecular Weight: 459.4658
MDL Number: MFCD30377200
SMILES: CCS(=O)(=O)Nc1ccc(c(c1)c1cn(C)c(=O)c2c1cc[nH]2)Oc1ccc(cc1F)F
Properties
Complexity: 834  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 32  
Hydrogen Bond Acceptor Count: 7  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 6  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.9  
Literature fold

Title: Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor.

Journal: Journal of medicinal chemistry20171026

Title: EJ Faivre et al. Abstract 4694: ABBV-075, a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo

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