Home Other Building Blocks 1448237-05-5
1448237-05-5,MFCD30496702
Catalog No.:AA01EO5L

1448237-05-5 | Naquotinib mesylate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
1 week  
$209.00   $147.00
- +
10mg
98%
1 week  
$320.00   $224.00
- +
25mg
98%
1 week  
$606.00   $424.00
- +
50mg
98%
1 week  
$924.00   $647.00
- +
100mg
98%
1 week  
$1,558.00   $1,091.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EO5L
Chemical Name:
Naquotinib mesylate
CAS Number:
1448237-05-5
Molecular Formula:
C31H46N8O6S
Molecular Weight:
658.8119
MDL Number:
MFCD30496702
SMILES:
CS(=O)(=O)O.C=CC(=O)N1CC[C@H](C1)Oc1nc(Nc2ccc(cc2)N2CCC(CC2)N2CCN(CC2)C)c(nc1CC)C(=O)N
Properties
Computed Properties
 
Complexity:
976  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
46  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
9  

Literature

Title: Sakagami H, et al. ASP8273, a novel mutant-selective irreversible EGFR inhibitor, inhibits growth of non-small cell lung cancer (NSCLC) cells with EGFR activating and T790M resistance mutations. [abstract In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 1728. doi:10.1158/1538-7445.AM2014-1728

Title: Konagai S, et al. ASP8273 selectively inhibits mutant EGFR signal pathway and induces tumor shrinkage in EGFR mutated tumor models. [abstract In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 2586. doi:10.1158/1538-7445.AM2015-2586

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SDS
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