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Home Other Building Blocks 1448428-04-3
1448428-04-3,MFCD29920355
Catalog No.:AA00ABQH

1448428-04-3 | Selonsertib

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
97%
in stock  
$68.00   $48.00
- +
250mg
97%
in stock  
$110.00   $77.00
- +
1g
97%
in stock  
$294.00   $206.00
- +
  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00ABQH
Chemical Name:
Selonsertib
CAS Number:
1448428-04-3
Molecular Formula:
C24H24FN7O
Molecular Weight:
445.4921
MDL Number:
MFCD29920355
SMILES:
O=C(c1cc(c(cc1F)C)n1cnc(c1)C1CC1)Nc1cccc(n1)c1nncn1C(C)C
Properties
Computed Properties
 
Complexity:
692  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
2.7  

Literature

Title: Distribution of lead, zinc and calcium in Dendrobaena rubida (Oligochaeta) living in soil contaminated by base metal mining in Wales.

Journal: Comparative biochemistry and physiology. B, Comparative biochemistry 19751215

Title: Lanier M, et al. Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure. ACS Med Chem Lett. 2017 Feb 8;8(3):316-320.

Title: Lin JH, et al. Design of a phase 2 clinical trial of an ASK1 inhibitor, GS-4997, in patients with diabetic kidney disease. Nephron. 2015;129(1):29-33.

Title: Loomba R, et al. The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2trial. Hepatology. 2018 Feb;67(2):549-559.

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Tags:1448428-04-3 Molecular Formula|1448428-04-3 MDL|1448428-04-3 SMILES|1448428-04-3 Selonsertib