Name: Name:2-chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one
Brand: AABLOCKS
SKU: AA00AN2J
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00AN2J

Chemical Name: 2-chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS Number: 1449598-86-0

Molecular Formula: C8H4ClFN2O

Molecular Weight: 198.5816

MDL Number: MFCD28659052

SMILES: Fc1ccc2n(c1)c(=O)cc(n2)Cl

Properties

Downstream Synthesis Route

1449598-85-9

1449598-86-0

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2016/184832,2016,A1Locationinpatent:Page/Pagecolumn37

[2]CurrentPatentAssignee:PTCTHERAPEUTICSINC;ROCHEHOLDINGAG-WO2013/119916,2013,A2Locationinpatent:Paragraph001254

[3]CurrentPatentAssignee:ROCHEHOLDINGAG;PTCTHERAPEUTICSINC-WO2015/173181,2015,A1Locationinpatent:Page/Pagecolumn31

[4]Woll,MatthewG.;Qi,Hongyan;Turpoff,Anthony;Zhang,Nanjing;Zhang,Xiaoyan;Chen,Guangming;Li,Chunshi;Huang,Song;Yang,Tianle;Moon,Young-Choon;Lee,Chang-Sun;Choi,Soongyu;Almstead,NeilG.;Naryshkin,NikolaiA.;Dakka,Amal;Narasimhan,Jana;Gabbeta,Vijayalakshmi;Welch,Ellen;Zhao,Xin;Risher,Nicole;Sheedy,Josephine;Weetall,Marla;Karp,GaryM.[JournalofMedicinalChemistry,2016,vol.59,#13,p.6070-6085]

[5]Ratni,Hasane;Karp,GaryM.;Weetall,Marla;Naryshkin,NikolaiA.;Paushkin,SergeyV.;Chen,KarenS.;McCarthy,KathleenD.;Qi,Hongyan;Turpoff,Anthony;Woll,MatthewG.;Zhang,Xiaoyan;Zhang,Nanjing;Yang,Tianle;Dakka,Amal;Vazirani,Priya;Zhao,Xin;Pinard,Emmanuel;Green,Luke;David-Pierson,Pascale;Tuerck,Dietrich;Poirier,Agnes;Muster,Wolfgang;Kirchner,Stephan;Mueller,Lutz;Gerlach,Irene;Metzger,Friedrich[JournalofMedicinalChemistry,2016,vol.59,#13,p.6086-6100]Ratni,Hasane;Ebeling,Martin;Baird,John;Bendels,Stefanie;Bylund,Johan;Chen,KarenS.;Denk,Nora;Feng,Zhihua;Green,Luke;Guerard,Melanie;Jablonski,Philippe;Jacobsen,Bjoern;Khwaja,Omar;Kletzl,Heidemarie;Ko,Chien-Ping;Kustermann,Stefan;Marquet,Anne;Metzger,Friedrich;Mueller,Barbara;Naryshkin,NikolaiA.;Paushkin,SergeyV.;Pinard,Emmanuel;Poirier,Agnès;Reutlinger,Michael;Weetall,Marla;Zeller,Andreas;Zhao,Xin;Mueller,Lutz[JournalofMedicinalChemistry,2018,vol.61,#15,p.6501-6517]

[6]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2017/81111,2017,A1Locationinpatent:Page/Pagecolumn31;32

[7]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2017/80967,2017,A1Locationinpatent:Page/Pagecolumn53

[8]CurrentPatentAssignee:PTCTHERAPEUTICSINC;ROCHEHOLDINGAG;PTCTHERANENTICS-US2019/315773,2019,A1Locationinpatent:Paragraph0255;0257

1449598-86-0

1825352-65-5

[1]CurrentPatentAssignee:ROCHEHOLDINGAG;PTCTHERAPEUTICSINC-WO2015/173181,2015,A1

[2]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2017/81111,2017,A1

[3]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2017/80967,2017,A1

[4]CurrentPatentAssignee:PTCTHERAPEUTICSINC;ROCHEHOLDINGAG;PTCTHERANENTICS-US2019/315773,2019,A1

1449598-86-0 | 2-chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one