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1450-85-7,MFCD00006073
Catalog No.:AA001KDF

1450-85-7 | 2-Mercaptopyrimidine

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10g
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25g
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$16.00   $11.00
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100g
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500g
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  • Technical Information
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Technical Information
Catalog Number:
AA001KDF
Chemical Name:
2-Mercaptopyrimidine
CAS Number:
1450-85-7
Molecular Formula:
C4H4N2S
Molecular Weight:
112.1530
MDL Number:
MFCD00006073
SMILES:
S=c1nccc[nH]1
Properties
Properties
 
BP:
191.3±23.0°C at 760 mmHg  
Form:
Solid  
MP:
230°C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
137  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
XLogP3:
-1.1  

Literature

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Title: Metal ion-binding properties of DNA duplexes containing thiopyrimidine base pairs.

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Title: 2,2'-(Disulfanedi-yl)bis-[4,6-(4-fluoro-phen-yl)pyrimidine].

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Title: Facile synthesis of oxo-/thioxopyrimidines and tetrazoles C-C linked to sugars as novel non-toxic antioxidant acetylcholinesterase inhibitors.

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Title: Electrical conductivity and luminescence in coordination polymers based on copper(I)-halides and sulfur-pyrimidine ligands.

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Title: A new investigation for some steroidal derivatives as anti-Alzheimer agents.

Journal: International journal of biological macromolecules 20120101

Title: Triarylmethanes, a new class of cx50 inhibitors.

Journal: Frontiers in pharmacology 20120101

Title: Synthesis, antitumor and antimicrobial testing of some new thiopyrimidine analogues.

Journal: Chemical & pharmaceutical bulletin 20120101

Title: tRNA structural and functional changes induced by oxidative stress.

Journal: Cellular and molecular life sciences : CMLS 20111201

Title: tert-Butyl N-[3-hy-droxy-1-phenyl-4-(pyrimidin-2-ylsulfan-yl)butan-2-yl]carbamate monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20110901

Title: Preliminary finding on a new calcium channel entry blocker chemotype: 5,6-diamino-4-hydroxy-2-mercaptopyrimidine derivatives.

Journal: Journal of medicinal chemistry 20110811

Title: Synthesis and anticancer activity of some novel tetralin-6-yl-pyrazoline, 2-thioxopyrimidine, 2-oxopyridine, 2-thioxo-pyridine and 2-iminopyridine derivatives.

Journal: Molecules (Basel, Switzerland) 20110420

Title: Design, Synthesis and Biological Evaluation of Novel Pyrimido[4,5-d]pyrimidine CDK2 Inhibitors as Anti-Tumor Agents.

Journal: Scientia pharmaceutica 20110101

Title: Nanocomposites of size-controlled gold nanoparticles and graphene oxide: formation and applications in SERS and catalysis.

Journal: Nanoscale 20101201

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Title: 1,4-Bis(pyrimidin-2-yl-sulfanyl)-butane.

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Journal: European journal of medicinal chemistry 20100401

Title: Structural motifs and biological studies of new antimony(III) iodide complexes with thiones.

Journal: Inorganic chemistry 20100118

Title: Structural properties, cytotoxicity, and anti-inflammatory activity of silver(I) complexes with tris(p-tolyl)phosphine and 5-chloro-2-mercaptobenzothiazole.

Journal: Bioinorganic chemistry and applications 20100101

Title: Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor.

Journal: BMC structural biology 20100101

Title: 'Lantern-Shaped' Platinum(III) Complexes with Axially Bound 9-Ethylguanine or 1-Methylcytosine (L) of General Formula [Pt(2){HN=C(Bu)O}(4)L(2)](NO(3))(2).

Journal: Bioinorganic chemistry and applications 20100101

Title: Recent trends in monitoring of European water framework directive priority substances using micro-sensors: a 2007-2009 review.

Journal: Sensors (Basel, Switzerland) 20100101

Title: EC-STM study of potential-controlled adsorption of substituted pyrimidinethiol on Au(111).

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Title: trans-Bis(4,6-dimethyl-pyrimidine-2-thiol-ato-κN,S)bis-(thio-urea-κS)nickel(II).

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: Synthesis, antimicrobial and antioxidant activities of substituted pyrazoles, isoxazoles, pyrimidine and thioxopyrimidine derivatives.

Journal: European journal of medicinal chemistry 20091101

Title: trans-(Pyrimidine-2-thiol-ato-κN,S)[tris-(2-amino-ethyl)amine-κN,N',N'',N''']cobalt(III) chloride hexa-fluoridophosphate.

Journal: Acta crystallographica. Section E, Structure reports online 20090901

Title: 4,6-Dimeth-oxy-2-(methyl-sulfan-yl)pyrimidine.

Journal: Acta crystallographica. Section E, Structure reports online 20090801

Title: Kinetic and thermodynamic uranyl (II) adsorption process into modified Na-Magadiite and Na-Kanemite.

Journal: Journal of hazardous materials 20090730

Title: Synthesis, structure and reactivity of tetranuclear square-type complexes of rhenium and manganese bearing pyrimidine-2-thiolate (pymS) ligands: versatile and efficient precursors for mono- and polynuclear compounds containing M(CO)(3) (M = Re, Mn) fragments.

Journal: Dalton transactions (Cambridge, England : 2003) 20090621

Title: Synthesis and in vitro antitumor activity of new substituted thiopyrimidine acyclic nucleosides and their thioglycoside analogs.

Journal: Nucleosides, nucleotides & nucleic acids 20090401

Title: New antimony(III) bromide complexes with thioamides: synthesis, characterization, and cytostatic properties.

Journal: Inorganic chemistry 20090302

Title: Synthesis, characterization, and biological studies of organotin(IV) derivatives with o- or p-hydroxybenzoic acids.

Journal: Bioinorganic chemistry and applications 20090101

Title: 1,2,3,4-tetrahydro-2-thioxopyrimidine analogs of combretastatin-A4.

Journal: European journal of medicinal chemistry 20080901

Title: Synthesis, characterization, and in vitro cytotoxicity of some gold(I) and trans platinum(II) thionate complexes containing water-soluble PTA and DAPTA ligands. X-ray crystal structures of [Au(SC4H3N2)(PTA)], trans-[Pt(SC4H3N2)2(PTA)2], trans-[Pt(SC5H4N)2(PTA)2], and trans-[Pt(SC5H4N)2(DAPTA)2].

Journal: Inorganic chemistry 20080707

Title: In vitro-refolding of a single-chain Fv fragment in the presence of heteroaromatic thiols.

Journal: Journal of biotechnology 20080430

Title: An optical chemical sensor for mercury ion based on 2-mercaptopyrimidine in PVC membrane.

Journal: Analytical and bioanalytical chemistry 20080401

Title: Preferential protonation and methylation site of thiopyrimidine derivatives in solution: NMR data.

Journal: The journal of physical chemistry. B 20080313

Title: Electrochemical oxidation of 2-pyrimidinethiols and theoretical study of their dimers, disulfides, sulfenyl radicals, and tautomers.

Journal: The journal of physical chemistry. A 20080221

Title: Concise syntheses of D-desosamine, 2-thiopyrimidinyl desosamine donors, and methyl desosaminide analogues from D-glucose.

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Title: Crystal structure and antitumor activity of the novel zwitterionic complex of tri-n-butyltin(IV) with 2-thiobarbituric acid.

Journal: Bioinorganic chemistry and applications 20080101

Title: Synthesis, Spectroscopic, and Anticancerous Properties of Mixed Ligand Palladium(II) and Silver(I) Complexes with 4,6-Diamino-5-hydroxy-2-mercaptopyrimidine and 2,2'-Bipyridyl.

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Title: The first metal complexes of 4,6-diamino-1-hydro-5-hydroxy-pyrimidine-2-thione: preparation, physical and spectroscopic studies, and preliminary antimicrobial properties.

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Title: Reaction mechanism and tautomeric equilibrium of 2-mercaptopyrimidine in the gas phase and in aqueous solution: a combined Monte Carlo and quantum mechanics study.

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Title: Structure-activity relationship of thiopyrimidines as mGluR5 antagonists.

Journal: Bioorganic & medicinal chemistry letters 20060501

Title: Molecular and vibrational structure of 2-mercapto pyrimidine and 2,4-diamino-6-hydroxy-5-nitroso pyrimidine: FT-IR, FT-Raman and quantum chemical calculations.

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Title: Photodegradation kinetics of some thiols and thiones in aqueous suspension of zinc oxide.

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Title: Mediatorless voltammetric oxidation of NADH and sensing of ethanol.

Journal: Biosensors & bioelectronics 20051215

Title: Oxidation process induced by 2-mercaptopyrimidine at a mercury electrode.

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Title: Synthesis and reactions of some new substituted pyridine and pyrimidine derivatives as analgesic, anticonvulsant and antiparkinsonian agents.

Journal: Archiv der Pharmazie 20050901

Title: Coordination polymers of copper(I) halides and neutral heterocyclic thiones with new coordination modes.

Journal: Inorganic chemistry 20050530

Title: Synthesis and biological evaluation of 2-thiopyrimidine derivatives.

Journal: Bioorganic & medicinal chemistry 20050502

Title: A new complex of HgBr2 and pyrimidine-2-thione: (pyrimidine-2-thionato-kappaS)(pyrimidinium-2-thionato-kappaS)mercury(II) tetrabromomercury(II).

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Title: Traceless solid-phase synthesis of nitrogen-containing heterocycles and their biological evaluations as inhibitors of neuronal sodium channels.

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Title: Interference-free determination of trace levels of gold and palladium in geological and metallurgical samples by flame atomic absorption spectrometry coupled with a flow injection on-line microcolumn preconcentration and separation system.

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Journal: Anticancer research 20020101

Title: Synthesis and antitumor evaluation of 6-thioxo-, 6-oxo- and 2,4-dioxopyrimidine derivatives.

Journal: Farmaco (Societa chimica italiana : 1989) 20011001

Title: Liquid-liquid extraction study of tellurium(IV) with N-n-octylaniline in halide medium and its separation from real samples.

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Title: The molecular basis of IgE antibody binding to thiopentone. Binding of IgE from thiopentone-allergic and non-allergic subjects.

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