Title: Inhibition of sirtuins 1 and 2 impairs cell survival and migration and modulates the expression of P-glycoprotein and MRP3 in hepatocellular carcinoma cell lines.
Journal: Toxicology letters 20180601
Title: Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3.
Journal: Journal of medicinal chemistry 20130509
Title: Efficacy of class I and II vs class III histone deacetylase inhibitors in neuroblastoma.
Journal: Journal of pediatric surgery 20120601
Title: Inhibition of SIRT1 impairs the accumulation and transcriptional activity of HIF-1α protein under hypoxic conditions.
Journal: PloS one 20120101
Title: Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile.
Journal: Bioorganic & medicinal chemistry 20110615
Title: SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability.
Journal: PLoS genetics 20110601
Title: Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition.
Journal: Experimental hematology 20091101
Title: Identification and characterization of novel sirtuin inhibitor scaffolds.
Journal: Bioorganic & medicinal chemistry 20091001
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
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Title: Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330.
