Home Amines 1454848-00-0
1454848-00-0,MFCD30803237
Catalog No.:AA001D0K

1454848-00-0 | Benzoic acid, 2-[(1R)-1-[(2-amino-5-bromo-3-pyridinyl)oxy]ethyl]-4-fluoro-, methyl ester

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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001D0K
Chemical Name:
Benzoic acid, 2-[(1R)-1-[(2-amino-5-bromo-3-pyridinyl)oxy]ethyl]-4-fluoro-, methyl ester
CAS Number:
1454848-00-0
Molecular Formula:
C15H14BrFN2O3
Molecular Weight:
369.1857
MDL Number:
MFCD30803237
SMILES:
COC(=O)c1ccc(cc1[C@H](Oc1cc(Br)cnc1N)C)F
Properties

Downstream Synthesis Route

[1]CurrentPatentAssignee:PFIZERINC-WO2013/132376,2013,A1

[2]Johnson,TedW.;Richardson,PaulF.;Bailey,Simon;Brooun,Alexei;Burke,BenjaminJ.;Collins,MichaelR.;Cui,J.Jean;Deal,JudithG.;Deng,Ya-Li;Dinh,Dac;Engstrom,LarsD.;He,Mingying;Hoffman,Jacqui;Hoffman,RobertL.;Huang,Qinhua;Kania,RobertS.;Kath,JohnC.;Lam,Hieu;Lam,JustineL.;Le,PhuongT.;Lingardo,Laura;Liu,Wei;McTigue,Michele;Palmer,CynthiaL.;Sach,NealW.;Smeal,Tod;Smith,GrahamL.;Stewart,AlbertE.;Timofeevski,Sergei;Zhu,Huichun;Zhu,Jinjiang;Zou,HelenY.;Edwards,MartinP.[JournalofMedicinalChemistry,2014,vol.57,#11,p.4720-4744]

[3]CurrentPatentAssignee:PFIZERINC-WO2014/207606,2014,A1

[4]Elleraas,Jeff;Ewanicki,Jason;Johnson,TedW.;Sach,NealW.;Collins,MichaelR.;Richardson,PaulF.[AngewandteChemie-InternationalEdition,2016,vol.55,#11,p.3590-3595][Angew.Chem.,2016,vol.128,p.3654-3659,6]

[5]CurrentPatentAssignee:NANJINGLEIZHENGPHARMACEUTICALTECH;JIANGNANUNIVERSITY-CN111362967,2020,A

Literature
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SDS
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Tags:1454848-00-0 Molecular Formula|1454848-00-0 MDL|1454848-00-0 SMILES|1454848-00-0 Benzoic acid, 2-[(1R)-1-[(2-amino-5-bromo-3-pyridinyl)oxy]ethyl]-4-fluoro-, methyl ester