Home PEG Linkers 145916-41-2
145916-41-2,MFCD29764327
Catalog No.:AA019E2K

145916-41-2 | Propargyl-peg2-tos

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250mg
95%
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$39.00   $28.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA019E2K
Chemical Name:
Propargyl-peg2-tos
CAS Number:
145916-41-2
Molecular Formula:
C12H14O4S
Molecular Weight:
254.3022
MDL Number:
MFCD29764327
SMILES:
C#CCOCCOS(=O)(=O)c1ccc(cc1)C
Properties

Downstream Synthesis Route

[1]Synthesis,1992,p.1164-1169

[2]Chemistry-AEuropeanJournal,2011,vol.17,p.2724-2733

[3]JournaloftheAmericanChemicalSociety,2013,vol.135,p.12004-12012

[4]EuropeanJournalofOrganicChemistry,2007,p.4711-4720

[5]AngewandteChemie-InternationalEdition,2014,vol.53,p.3854-3858    Angew.Chem.,2014,vol.126,p.3934-3939,5

[6]JournalofOrganicChemistry,2008,vol.73,p.249-258

[7]JournalofMedicinalChemistry,2018,vol.61,p.453-461

[8]BioorganicandMedicinalChemistryLetters,2016,vol.26,p.1993-1996

[9]JournalofOrganometallicChemistry,1985,vol.288,p.349-358

[10]Patent:WO2004/29066,2004,A2.Locationinpatent:Page/Pagecolumn281

[11]JournaloftheAmericanChemicalSociety,2012,vol.134,p.6491-6497

[12]BioorganicandMedicinalChemistryLetters,2014,vol.24,p.1538-1544

[13]CellChemicalBiology,2018,vol.25,p.1086-7,1094

145916-41-2    308085-25-8   
2-2-(prop-2-ynyloxy)ethoxy-4-3-(trifluoromethyl)-3H-diazirin-3-ylbenzaldehyde 

[1]Mayer,Timo;Maier,MartinE.[EuropeanJournalofOrganicChemistry,2007,#28,p.4711-4720]

[1]Harada,Toshiro;Muramatsu,Keiko;Mizunashi,Kenia;Kitano,Chie;Imaoka,Daisuke;Fujiwara,Takayuki;Kataoka,Hiroshi[JournalofOrganicChemistry,2008,vol.73,#1,p.249-258]

126-58-9    145916-41-2   
C40H58O13 

[1]Chemistry-AEuropeanJournal,2018,vol.24,p.1694-1700

64567-60-8    145916-41-2   
2-(2,6-dioxopiperidin-3-yl)-5-(2-(prop-2-yn-1-yloxy)ethoxy)isoindoline-1,3-dione 

[1]CurrentPatentAssignee:ARVINAS-US2018/125821,2018,A1Locationinpatent:Paragraph0862;0863

[2]CurrentPatentAssignee:ARVINAS-WO2021/11913,2021,A1Locationinpatent:Paragraph0570;0571;1282;1283

Literature

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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