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146374-27-8,MFCD01863616
Catalog No.:AA00HXEV

146374-27-8 | 2-Methyl-2-propanesulfinamide

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5g
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10g
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25g
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00HXEV
Chemical Name:
2-Methyl-2-propanesulfinamide
CAS Number:
146374-27-8
Molecular Formula:
C4H11NOS
Molecular Weight:
121.2012
MDL Number:
MFCD01863616
SMILES:
CC(S(=O)N)(C)C
Properties
Properties
 
BP:
220°C at 760 mmHg  
Form:
Solid  
MP:
97-101 °C  
Solubility:
Soluble in methanol.  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
84.2  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Chiral sulfur compounds studied by Raman optical activity: tert-butanesulfinamide and its precursor tert-butyl tert-butanethiosulfinate.

Journal: Chirality 20120901

Title: Microwave-assisted solvent-free synthesis of enantiomerically pure N-(tert-butylsulfinyl)imines.

Journal: The Journal of organic chemistry 20120706

Title: The enantiomers of epiboxidine and of two related analogs: synthesis and estimation of their binding affinity at α4β2 and α7 neuronal nicotinic acetylcholine receptors.

Journal: Chirality 20120701

Title: Palladium-catalyzed C-N cross coupling of sulfinamides and aryl halides.

Journal: The Journal of organic chemistry 20120504

Title: Lewis acid promoted highly diastereoselective Petasis Borono-Mannich reaction: efficient synthesis of optically active β,γ-unsaturated α-amino acids.

Journal: Organic letters 20120420

Title: Stereoselective synthesis of novel pyrazole derivatives using tert-butansulfonamide as a chiral auxiliary.

Journal: Organic & biomolecular chemistry 20120407

Title: Stereoselective synthesis of cis-2,5-disubstituted pyrrolidines via Wacker-type aerobic oxidative cyclization of alkenes with tert-butanesulfinamide nucleophiles.

Journal: Organic letters 20120302

Title: Chiral N-tert-butanesulfinyl α,β-unsaturated ketimine: a simple and highly effective olefin/sulfinimide hybrid ligand for asymmetric 1,4-additions.

Journal: Organic & biomolecular chemistry 20110907

Title: Synthesis of β,γ-dihydroxyhomotyrosines by a tandem Petasis-asymmetric dihydroxylation approach.

Journal: Organic letters 20110603

Title: Thermal rearrangement of tert-butylsulfinamide.

Journal: Beilstein journal of organic chemistry 20110101

Title: Stereoselective α-aminoallylation of aldehydes with chiral tert-butanesulfinamides and allyl bromides.

Journal: The Journal of organic chemistry 20100917

Title: Synthesis and applications of tert-butanesulfinamide.

Journal: Chemical reviews 20100609

Title: The tert-butylsulfinamide lynchpin in transition-metal-mediated multiscaffold library synthesis.

Journal: Organic letters 20100507

Title: Discovery of 4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides as selective, orally active inhibitors of protein kinase B (Akt).

Journal: Journal of medicinal chemistry 20100311

Title: Asymmetric synthesis of alpha-alkylated N-sulfinyl imidates as new chiral building blocks.

Journal: The Journal of organic chemistry 20090515

Title: General one-pot method for the preparation of N-tert-butanesulfinylamine diastereomer mixtures as standards for stereoselectivity determinations.

Journal: The Journal of organic chemistry 20090501

Title: Highly stereoselective methylene transfers onto butanediacetal-protected chiral non-racemic sulfinyl imines using S-ylide technology.

Journal: Chemical communications (Cambridge, England) 20090414

Title: Recycling the tert-butanesulfinyl group in the synthesis of amines using tert-butanesulfinamide.

Journal: The Journal of organic chemistry 20090403

Title: A scalable synthesis of an azabicyclooctanyl derivative, a novel DPP-4 inhibitor.

Journal: The Journal of organic chemistry 20081121

Title: Sequential C-Si bond formations from diphenylsilane: application to silanediol peptide isostere precursors.

Journal: Journal of the American Chemical Society 20081001

Title: An advance on exploring N-tert-butanesulfinyl imines in asymmetric synthesis of chiral amines.

Journal: Accounts of chemical research 20080701

Title: Expedient synthesis of N-methyl tubulysin analogues with high cytotoxicity.

Journal: The Journal of organic chemistry 20080620

Title: An efficient and versatile approach for optical resolution of C2-symmetric axially chiral biaryl dials. Synthesis of enantiopure biaryl-derived cyclic trans-1,2-diols.

Journal: Organic letters 20080320

Title: Chiroptical spectroscopic determination of molecular structures of chiral sulfinamides: t-butanesulfinamide.

Journal: The journal of physical chemistry. A 20071101

Title: One-pot asymmetric synthesis of either diastereomer of tert-butanesulfinyl-protected amines from ketones.

Journal: The Journal of organic chemistry 20070119

Title: The total synthesis of tubulysin D.

Journal: Journal of the American Chemical Society 20061220

Title: Practical asymmetric synthesis of alpha-branched 2-piperazinylbenzylamines by 1,2-additions of organometallic reagents to N-tert-butanesulfinyl imines.

Journal: The Journal of organic chemistry 20051028

Title: A rapid and general method for the asymmetric synthesis of 2-substituted pyrrolidines using tert-butanesulfinamide.

Journal: Organic & biomolecular chemistry 20050607

Title: Highly stereoselective addition of organometallic reagents to N-tert-butanesulfinyl imines derived from 3- and 4-substituted cyclohexanones.

Journal: Organic letters 20040513

Title: Improved synthesis of tert-butanesulfinamide suitable for large-scale production.

Journal: Organic letters 20030417

Title: N-tert-butanesulfinyl imines: versatile intermediates for the asymmetric synthesis of amines.

Journal: Accounts of chemical research 20021101

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