Name: Name:H-Trp(Boc)-OH
Brand: AABLOCKS
SKU: AA00HXFK
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00HXFK

Chemical Name: H-Trp(Boc)-OH

CAS Number: 146645-63-8

Molecular Formula: C16H20N2O4

Molecular Weight: 304.3410

MDL Number: MFCD21601394

SMILES: OC(=O)[C@H](Cc1cn(c2c1cccc2)C(=O)OC(C)(C)C)N

Properties

Complexity: 432

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 22

Hydrogen Bond Acceptor Count: 5

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 5

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: -0.1

Downstream Synthesis Route

146645-63-8

333366-28-2

[1]Lundquist4th.;Pelletier[Organicletters,2001,vol.3,#5,p.781-783]

[2]Valverde,IbaiE.;Bauman,Andreas;Kluba,ChristianeA.;Vomstein,Sandra;Walter,MartinA.;Mindt,ThomasL.[AngewandteChemie-InternationalEdition,2013,vol.52,#34,p.8957-8960][Angew.Chem.,2013,vol.125,#34,p.9126-9129,4]

57710-80-2

(2S)-2-amino-3-(1-tert-butoxycarbonylindol-3-yl)propanoicacid

131829-26-0

[1]Abato,Paul;Yuen,CourtneyM.;Cubanski,JeanneY.;Seto,ChristopherT.[JournalofOrganicChemistry,2002,vol.67,#4,p.1184-1191]

146645-63-8

191221-36-0

[1]Samuels,EricR.;Sevrioukova,IrinaF.[TetrahedronLetters,2018,vol.59,#12,p.1140-1142]

[2]Moumne,Roba;Lavielle,Solange;Karoyan,Philippe[JournalofOrganicChemistry,2006,vol.71,#8,p.3332-3334]

[3]Moumne,Roba;Denise,Bernard;Guitot,Karine;Rudler,Henri;Lavielle,Solange;Karoyan,Philippe[EuropeanJournalofOrganicChemistry,2007,#12,p.1912-1920]

[4]Gu,Renjie;Hong,Bin;Hu,Xiaomin;Hu,Xiaowen;Jiang,Bingya;Jiang,Zhibo;Li,Xingxing;Shi,Yuanyuan;Sun,Hongmin;Wang,Lifei;Wu,Linzhuan;Zhang,Cong;Zuo,Lijie[AngewandteChemie-InternationalEdition,2021,vol.60,#28,p.15399-15404][Angew.Chem.,2021,vol.133,#28,p.15527-15532]

CASUnavailable

146645-63-8

CASUnavailable

[1]CurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz)-US5703106,1997,A

1694-92-4

146645-63-8

1021421-66-8

[1]Wang,Deyun;Lu,Min;Arora,ParamjitS.[AngewandteChemie-InternationalEdition,2008,vol.47,#10,p.1879-1882]

[2]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2017/72062,2017,A1Locationinpatent:Page/Pagecolumn169