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Home Other Building Blocks 1469337-95-8
1469337-95-8,MFCD28016953
Catalog No.:AA001ECY

1469337-95-8 | K-Ras(G12C) inhibitor 12

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$46.00   $32.00
- +
5mg
≥95%
in stock  
$208.00   $145.00
- +
10mg
≥95%
in stock  
$393.00   $275.00
- +
25mg
≥95%
in stock  
$816.00   $571.00
- +
100mg
97%
in stock  
$3,209.00   $2,247.00
- +
  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA001ECY
Chemical Name:
K-Ras(G12C) inhibitor 12
CAS Number:
1469337-95-8
Molecular Formula:
C15H17ClIN3O3
Molecular Weight:
449.6712
MDL Number:
MFCD28016953
SMILES:
C=CC(=O)N1CCN(CC1)C(=O)CNc1cc(I)c(cc1O)Cl
Properties
Computed Properties
 
Complexity:
457  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
2.2  

Literature

Title: K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.

Journal: Nature 20131128

Title: Ostrem JM, et al. K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature. 2013 Nov 28;503(7477):548-551.

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