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Home Fluorides 146954-75-8
146954-75-8,MFCD11113919
Catalog No.:AA001EEM

146954-75-8 | Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
95%
in stock  
$23.00   $16.00
- +
5g
95%
in stock  
$91.00   $64.00
- +
25g
95%
in stock  
$451.00   $316.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001EEM
Chemical Name:
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS Number:
146954-75-8
Molecular Formula:
C39H46FN4O8P
Molecular Weight:
748.7767
MDL Number:
MFCD11113919
SMILES:
N#CCCOP(N(C(C)C)C(C)C)O[C@@H]1[C@@H](COC(c2ccc(cc2)OC)(c2ccc(cc2)OC)c2ccccc2)O[C@H]([C@@H]1F)n1ccc(=O)[nH]c1=O
Properties
Computed Properties
 
Complexity:
1230  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
53  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
17  
Undefined Atom Stereocenter Count:
1  
XLogP3:
5.3  

Upstream Synthesis Route

[1]Patent:EP2816053,2014,A1,.Locationinpatent:Paragraph0371

[2]Patent:US9371353,2016,B2,.Locationinpatent:Page/Pagecolumn78

[1]JournalofMedicinalChemistry,1993,vol.36,#7,p.831-841

[1]HelveticaChimicaActa,1997,vol.80,#6,p.1952-1971

[1]HelveticaChimicaActa,1997,vol.80,#6,p.1952-1971

[2]JournalofMedicinalChemistry,1993,vol.36,#7,p.831-841

[1]HelveticaChimicaActa,1997,vol.80,#6,p.1952-1971

[2]JournalofMedicinalChemistry,1993,vol.36,#7,p.831-841

Downstream Synthesis Route
2-(Cyanethoxy)-bis-N,N-(diisopropylamino)phosphane 
  146954-74-7    146954-75-8 

[1]JournalofMedicinalChemistry,1993,vol.36,p.831-841

288-88-0    146954-75-8   
5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-N4-1,2,4-triazolouridine-3'-O-(O-cyanoethyl-N,N-diisopropylamino)phosphite 

[1]BioorganicandMedicinalChemistryLetters,1997,vol.7,p.1791-1796

[1]HelveticaChimicaActa,1997,vol.80,p.1952-1971

146954-75-8    161442-19-9   
protectedguanosine 
 
C94H114F6N36O67P10 

[1]HelveticaChimicaActa,1997,vol.80,p.1952-1971

[1]HelveticaChimicaActa,1997,vol.80,p.1952-1971

[2]JournalofMedicinalChemistry,1993,vol.36,p.831-841

Literature
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Tags:146954-75-8 Molecular Formula|146954-75-8 MDL|146954-75-8 SMILES|146954-75-8 Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]