Home Other Building Blocks 1469988-75-7
1469988-75-7,MFCD22124682
Catalog No.:AA00ABIO

1469988-75-7 | QL47

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
1 week  
$317.00   $222.00
- +
10mg
98%
1 week  
$470.00   $329.00
- +
50mg
98%
1 week  
$1,727.00   $1,209.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ABIO
Chemical Name:
QL47
CAS Number:
1469988-75-7
Molecular Formula:
C27H21N5O2
Molecular Weight:
447.4879
MDL Number:
MFCD22124682
SMILES:
C=CC(=O)N1CCc2c1cc(cc2)n1c(=O)ccc2c1c1cc(ccc1nc2)c1cnn(c1)C
Properties
Computed Properties
 
Complexity:
860  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
3.3  

Literature

Title: Liang Y, et al. Structure-Activity Relationship Study of QL47: A Broad-Spectrum Antiviral Agent. ACS Med Chem Lett. 2017;8(3):344-349. Published 2017 Feb 3.

Title: de Wispelaere M, et al. A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation. J Biol Chem. 2020;295(6):1694-1703.

Title: Wu H, et al. Discovery of a potent, covalent BTK inhibitor for B-cell lymphoma. ACS Chem Biol. 2014;9(5):1086-1091.

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SDS
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