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Home Amines 147059-75-4
147059-75-4,MFCD00913361
Catalog No.:AA001EI5

147059-75-4 | 1,8-Naphthyridine-3-carboxylic acid, 7-[(1α,5α,6α)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, methanesulfonate (1:1)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$123.00   $86.00
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10mg
≥98%
in stock  
$218.00   $152.00
- +
50mg
100%
in stock  
$824.00   $577.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001EI5
Chemical Name:
1,8-Naphthyridine-3-carboxylic acid, 7-[(1α,5α,6α)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, methanesulfonate (1:1)
CAS Number:
147059-75-4
Molecular Formula:
C20H15F3N4O3
Molecular Weight:
416.3533
MDL Number:
MFCD00913361
SMILES:
NC1[C@@H]2[C@H]1CN(C2)c1nc2c(cc1F)c(=O)c(cn2c1ccc(cc1F)F)C(=O)O
Properties
Computed Properties
 
Complexity:
863  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  

Literature

Title: Post-approval translational research itself has diverse ethics.

Journal: The American journal of bioethics : AJOB 20100801

Title: Ethical problems in conducting research in acute epidemics: the Pfizer meningitis study in Nigeria as an illustration.

Journal: Developing world bioethics 20100401

Title: Understanding informed consent for participation in international health research.

Journal: Developing world bioethics 20090801

Title: Globalized clinical trials and informed consent.

Journal: The New England journal of medicine 20090514

Title: Drug company trials come under increasing scrutiny.

Journal: Lancet (London, England) 20080119

Title: Pfizer lawsuit spotlights ethics of developing world clinical trials.

Journal: Nature medicine 20070701

Title: Secret report surfaces showing that Pfizer was at fault in Nigerian drug tests.

Journal: BMJ (Clinical research ed.) 20060527

Title: Sequential IV/PO moxifloxacin treatment of patients with severe community-acquired pneumonia.

Journal: Respiratory medicine 20031001

Title: Effects of alatrofloxacin, the parental prodrug of trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20031001

Title: Nigerians in drug trial take their case to US court.

Journal: BMJ (Clinical research ed.) 20030426

Title: Pfizer in 'unethical' trial suit.

Journal: Nature medicine 20011001

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Tags:147059-75-4 Molecular Formula|147059-75-4 MDL|147059-75-4 SMILES|147059-75-4 1,8-Naphthyridine-3-carboxylic acid, 7-[(1α,5α,6α)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, methanesulfonate (1:1)