Title: Phthalates efficiently bind to human peroxisome proliferator activated receptor and retinoid X receptor α, β, γ subtypes: an in silico approach.
Journal: Journal of applied toxicology : JAT20140701
Title: Estimated phytanic acid intake and prostate cancer risk: a prospective cohort study.
Journal: International journal of cancer20120915
Title: Phytanic acid disturbs mitochondrial homeostasis in heart of young rats: a possible pathomechanism of cardiomyopathy in Refsum disease.
Journal: Molecular and cellular biochemistry20120701
Title: A child with night blindness: preventing serious symptoms of Refsum disease.
Journal: Journal of child neurology20120501
Title: Tiptoeing around transgenics.
Journal: Nature biotechnology20120307
Title: [The diagnostic of peroxisomic diseases in children].
Journal: Klinicheskaia laboratornaia diagnostika20120301
Title: Long-term strategies for the treatment of Refsum's disease using therapeutic apheresis.
Journal: Journal of clinical apheresis20120101
Title: Morphology of 1-methyl-1-nitrosourea induced rat mammary tumours after treatment with precursor of phytanic acid or its combination with vitamin D analogue.
Journal: Endocrine regulations20120101
Title: Chance and serendipity in science: two examples from my own career.
Journal: The Journal of biological chemistry20111104
Title: Phytanic acid metabolism in health and disease.
Journal: Biochimica et biophysica acta20110901
Title: Analysis of a range of catabolic mutants provides evidence that phytanoyl-coenzyme A does not act as a substrate of the electron-transfer flavoprotein/electron-transfer flavoprotein:ubiquinone oxidoreductase complex in Arabidopsis during dark-induced senescence.
Journal: Plant physiology20110901
Title: Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40.
Journal: Neurobiology of disease20110801
Title: AMACR polymorphisms, dietary intake of red meat and dairy and prostate cancer risk.
Journal: The Prostate20110401
Title: Refsum's Disease-Use of the Intestinal Lipase Inhibitor, Orlistat, as a Novel Therapeutic Approach to a Complex Disorder.
Journal: Journal of obesity20110101
Title: Effect of dairy fat on plasma phytanic acid in healthy volunteers - a randomized controlled study.
Journal: Lipids in health and disease20110101
Title: Peroxisomal biogenesis disorder biomarkers.
Journal: Clinical laboratory20110101
Title: Alkyl-glycerol rescues plasmalogen levels and pathology of ether-phospholipid deficient mice.
Journal: PloS one20110101
Title: Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism.
Journal: Journal of lipid research20101001
Title: In vitro evidence that phytanic acid compromises Na(+),K(+)-ATPase activity and the electron flow through the respiratory chain in brain cortex from young rats.
Journal: Brain research20100917
Title: The effectiveness of long-term dietary therapy in the treatment of adult Refsum disease.
Journal: Journal of neurology, neurosurgery, and psychiatry20100901
Title: Neurochemical evidence that phytanic acid induces oxidative damage and reduces the antioxidant defenses in cerebellum and cerebral cortex of rats.
Journal: Life sciences20100828
Title: Plasma phytanic acid concentration and risk of prostate cancer: results from the European Prospective Investigation into Cancer and Nutrition.
Journal: The American journal of clinical nutrition20100601
Title: Lanthanide phytanates: liquid-crystalline phase behavior, colloidal particle dispersions, and potential as medical imaging agents.
Journal: Langmuir : the ACS journal of surfaces and colloids20100504
Title: A Pex7 hypomorphic mouse model for plasmalogen deficiency affecting the lens and skeleton.
Journal: Molecular genetics and metabolism20100401
Title: Use of polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline for the preparation of a hapten-protein conjugate for antibody development.
Journal: Bioorganic & medicinal chemistry letters20100301
Title: Phytanic acid--an overlooked bioactive fatty acid in dairy fat?
Journal: Annals of the New York Academy of Sciences20100301
Title: Compartmentalization of the Edinburgh Human Metabolic Network.
Journal: BMC bioinformatics20100101
Title: Adult Refsum disease: a form of tapetoretinal dystrophy accessible to therapy.
Journal: Survey of ophthalmology20100101
Title: Identification of differences in human and great ape phytanic acid metabolism that could influence gene expression profiles and physiological functions.
Journal: BMC physiology20100101
Title: Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis.
Journal: Proceedings of the National Academy of Sciences of the United States of America20091208
Title: The influence of the branched-chain fatty acids pristanic acid and Refsum disease-associated phytanic acid on mitochondrial functions and calcium regulation of hippocampal neurons, astrocytes, and oligodendrocytes.
Journal: Neurobiology of disease20091101
Title: A PEX10 defect in a patient with no detectable defect in peroxisome assembly or metabolism in cultured fibroblasts.
Journal: Journal of inherited metabolic disease20090201
Title: Phytol-induced hepatotoxicity in mice.
Journal: Toxicologic pathology20090101
Title: Identification of marker genes for lipid-lowering effect of a short-chain fructooligosaccharide by DNA microarray analysis.
Journal: Journal of dietary supplements20090101
Title: Rapid UPLC-MS/MS method for routine analysis of plasma pristanic, phytanic, and very long chain fatty acid markers of peroxisomal disorders.
Journal: Journal of lipid research20080801
Title: Comment concerning the article: 'Phytanic acid impairs mitochondrial respiration through protonophoric action' by Komen et al.: branched chain phytanic acid inhibits the activity of the mitochondrial respiratory chain.
Journal: Cellular and molecular life sciences : CMLS20080701
Title: Non-manifesting Refsum heterozygotes carrying the c.135-2A>G PAHX gene transition.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology20080601
Title: Refsum disease due to the splice-site mutation c.135-2A>G before exon 3 of the PHYH gene, diagnosed eight years after detection of retinitis pigmentosa.
Journal: Journal of the neurological sciences20080315
Title: Phytanic acid: measurement of plasma concentrations by gas-liquid chromatography-mass spectrometry analysis and associations with diet and other plasma fatty acids.
Journal: The British journal of nutrition20080301
Title: Plasmalogen levels in Gaucher disease.
Journal: Blood cells, molecules & diseases20080101
Title: Dietary fat-gene interactions in cancer.
Journal: Cancer metastasis reviews20071201
Title: Phytanic acid impairs mitochondrial respiration through protonophoric action.
Journal: Cellular and molecular life sciences : CMLS20071201
Title: Peroxisomes, Refsum's disease and the alpha- and omega-oxidation of phytanic acid.
Journal: Biochemical Society transactions20071101
Title: Peroxisomal disorders affecting phytanic acid alpha-oxidation: a review.
Journal: Biochemical Society transactions20071101
Title: Peroxisomes contain a specific phytanoyl-CoA/pristanoyl-CoA thioesterase acting as a novel auxiliary enzyme in alpha- and beta-oxidation of methyl-branched fatty acids in mouse.
Journal: The Journal of biological chemistry20070914
Title: Dual subcellular localization in the endoplasmic reticulum and peroxisomes and a vital role in protecting against oxidative stress of fatty aldehyde dehydrogenase are achieved by alternative splicing.
Journal: The Journal of biological chemistry20070713
Title: Effect of SCP-x gene ablation on branched-chain fatty acid metabolism.
Journal: American journal of physiology. Gastrointestinal and liver physiology20070301
Title: Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid.
Journal: Journal of lipid research20070101
Title: PPARs in the Control of Uncoupling Proteins Gene Expression.
Journal: PPAR research20070101
Title: Alpha-oxidation.
Journal: Biochimica et biophysica acta20061201
Title: Refsum's disease may mimic familial Guillain Barre syndrome.
Journal: Neuromuscular disorders : NMD20061101
Title: CYP4 isoform specificity in the omega-hydroxylation of phytanic acid, a potential route to elimination of the causative agent of Refsum's disease.
Journal: The Journal of pharmacology and experimental therapeutics20060801
Title: Phytanic acid: production from phytol, its breakdown and role in human disease.
Journal: Cellular and molecular life sciences : CMLS20060801
Title: Identification of the cytochrome P450 enzymes responsible for the omega-hydroxylation of phytanic acid.
Journal: FEBS letters20060710
Title: A study of the cytotoxicity of branched-chain phytanic acid with mitochondria and rat brain astrocytes.
Journal: Experimental gerontology20060701
Title: Thiamine pyrophosphate: an essential cofactor for the alpha-oxidation in mammals--implications for thiamine deficiencies?
Journal: Cellular and molecular life sciences : CMLS20060701
Title: Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid.
Journal: FEBS letters20060612
Title: Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation.
Journal: FEBS letters20060403
Title: Phytanic acid, AMACR and prostate cancer risk.
Journal: Future oncology (London, England)20060401
Title: Rotenone-like action of the branched-chain phytanic acid induces oxidative stress in mitochondria.
Journal: The Journal of biological chemistry20060317
Title: Mechanism of toxicity of the branched-chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience20060101
Title: [alpha-Oxidation of 3-methyl-branched fatty acids: unraveling of a pathway].
Journal: Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie20060101
Title: Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.
Journal: The Journal of biological chemistry20051209
Title: Phytol directly activates peroxisome proliferator-activated receptor alpha (PPARalpha) and regulates gene expression involved in lipid metabolism in PPARalpha-expressing HepG2 hepatocytes.
Journal: Biochemical and biophysical research communications20051118
Title: Serum levels of phytanic acid are associated with prostate cancer risk.
Journal: The Journal of urology20051101
Title: [Adult Refsum disease. A retinal dystrophy with therapeutic options].
Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft20050801
Title: Characterization of the final step in the conversion of phytol into phytanic acid.
Journal: The Journal of biological chemistry20050722
Title: Characterization of phytanic acid omega-hydroxylation in human liver microsomes.
Journal: Molecular genetics and metabolism20050701
Title: [Refsum's disease with severe neuropathy: efficiency of the diet and plasmapheresis].
Journal: La Revue de medecine interne20050601
Title: Serum levels of phytanic acid are associated with prostate cancer risk.
Journal: The Prostate20050515
Title: Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids.
Journal: The Journal of biological chemistry20050318
Title: The Refsum disease marker phytanic acid, a branched chain fatty acid, affects Ca2+ homeostasis and mitochondria, and reduces cell viability in rat hippocampal astrocytes.
Journal: Neurobiology of disease20050201
Title: A study on the causes for the elevated n-3 fatty acids in cows' milk of alpine origin.
Journal: Lipids20050201
Title: Up-regulation of PPARgamma coactivator-1alpha as a strategy for preventing and reversing insulin resistance and obesity.
Journal: Medical hypotheses20050101
Title: Assay for Sjögren-Larsson syndrome based on a deficiency of phytol degradation.
Journal: Clinical chemistry20050101
Title: Orthotopic liver transplantation from a living-related donor in an infant with a peroxisome biogenesis defect of the infantile Refsum disease type.
Journal: Journal of inherited metabolic disease20050101
Title: A novel assay for the prenatal diagnosis of Sjögren-Larsson syndrome.
Journal: Journal of inherited metabolic disease20050101
Title: Clinical significance of oxidation from phytol to phytanic acid in man.
Journal: Molecular genetics and metabolism20041201
Title: Potentiation of the teratogenic effects induced by coadministration of retinoic acid or phytanic acid/phytol with synthetic retinoid receptor ligands.
Journal: Archives of toxicology20041101
Title: Phytanic acid accumulation is associated with conduction delay and sudden cardiac death in sterol carrier protein-2/sterol carrier protein-x deficient mice.
Journal: Journal of cardiovascular electrophysiology20041101
Title: In brain mitochondria the branched-chain fatty acid phytanic acid impairs energy transduction and sensitizes for permeability transition.
Journal: The Biochemical journal20041001
Title: Tremor and deep white matter changes in alpha-methylacyl-CoA racemase deficiency.
Journal: Neurology20040713
Title: Omega-hydroxylation of phytanic acid in rat liver microsomes: implications for Refsum disease.
Journal: Journal of lipid research20040701
Title: Hyperpipecolic acidaemia: a diagnostic tool for peroxisomal disorders.
Journal: Molecular genetics and metabolism20040701
Title: Reinvestigation of trihydroxycholestanoic acidemia reveals a peroxisome biogenesis disorder.
Journal: Neurology20040608
Title: Identification of fatty aldehyde dehydrogenase in the breakdown of phytol to phytanic acid.
Journal: Molecular genetics and metabolism20040501
Title: Liver fatty acid binding protein expression enhances branched-chain fatty acid metabolism.
Journal: Molecular and cellular biochemistry20040401
Title: Molecular basis of Refsum disease: sequence variations in phytanoyl-CoA hydroxylase (PHYH) and the PTS2 receptor (PEX7).
Journal: Human mutation20040301
Title: Measurement of plasma pristanic, phytanic and very long chain fatty acids by liquid chromatography-electrospray tandem mass spectrometry for the diagnosis of peroxisomal disorders.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20031205
Title: Further studies on the substrate spectrum of phytanoyl-CoA hydroxylase: implications for Refsum disease?
Journal: Journal of lipid research20031201
Title: Gas chromatography/mass spectrometry analysis of very long chain fatty acids, docosahexaenoic acid, phytanic acid and plasmalogen for the screening of peroxisomal disorders.
Journal: Brain & development20031001
Title: Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata.
Journal: Human molecular genetics20030915
Title: Sterol carrier protein-2/sterol carrier protein-x expression differentially alters fatty acid metabolism in L cell fibroblasts.
Journal: Journal of lipid research20030901
Title: The chemical biology of branched-chain lipid metabolism.
Journal: Progress in lipid research20030901
Title: Metabolism of phytanic acid and 3-methyl-adipic acid excretion in patients with adult Refsum disease.
Journal: Journal of lipid research20030801
Title: Membrane differential filtration is safe and effective for the long-term treatment of Refsum syndrome--an update of treatment modalities and pathophysiological cognition.
Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis20030801
Title: Branched fatty acids in dairy and beef products markedly enhance alpha-methylacyl-CoA racemase expression in prostate cancer cells in vitro.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology20030801
Title: Hearing loss in adult Refsum's disease.
Journal: Clinical otolaryngology and allied sciences20030601
Title: Alpha-oxidation of 3-methyl-substituted fatty acids and its thiamine dependence.
Journal: European journal of biochemistry20030401
Title: Phytanic acid alpha-oxidation, new insights into an old problem: a review.
Journal: Biochimica et biophysica acta20030317
Title: Identification of PEX7 as the second gene involved in Refsum disease.
Journal: American journal of human genetics20030201
Title: Biochemical markers predicting survival in peroxisome biogenesis disorders.
Journal: Advances in experimental medicine and biology20030101
Title: Phytanic and pristanic acid are naturally occuring ligands.
Journal: Advances in experimental medicine and biology20030101
Title: Role of phytanoyl-CoA 2-hydroxylase in phytanic acid metabolism.
Journal: Advances in experimental medicine and biology20030101
Title: Branched chain fatty acids induce nitric oxide-dependent apoptosis in vascular smooth muscle cells.
Journal: The Journal of biological chemistry20021220
Title: Biochemical markers predicting survival in peroxisome biogenesis disorders.
Journal: Neurology20021210
Title: Expression of fatty acid binding proteins inhibits lipid accumulation and alters toxicity in L cell fibroblasts.
Journal: American journal of physiology. Cell physiology20020901
Title: The chlorophyll-derived metabolite phytanic acid induces white adipocyte differentiation.
Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity20020901
Title: [Refsum disease].
Journal: Nihon rinsho. Japanese journal of clinical medicine20020901
Title: Phytanic acid, a natural peroxisome proliferator-activated receptor (PPAR) agonist, regulates glucose metabolism in rat primary hepatocytes.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20020501
Title: Glucuronidation of the dietary fatty acids, phytanic acid and docosahexaenoic acid, by human UDP-glucuronosyltransferases.
Journal: Drug metabolism and disposition: the biological fate of chemicals20020501
Title: Utilization of sterol carrier protein-2 by phytanoyl-CoA 2-hydroxylase in the peroxisomal alpha oxidation of phytanic acid.
Journal: Chemistry & biology20020501
Title: Phytanic acid, but not pristanic acid, mediates the positive effects of phytol derivatives on brown adipocyte differentiation.
Journal: FEBS letters20020424
Title: Photoaffinity labeling of human retinoid X receptor beta (RXRbeta) with 9-cis-retinoic acid: identification of phytanic acid, docosahexaenoic acid, and lithocholic acid as ligands for RXRbeta.
Journal: Biochemistry20020416
Title: Prevention of vitamin A teratogenesis by phytol or phytanic acid results from reduced metabolism of retinol to the teratogenic metabolite, all-trans-retinoic acid.
Journal: Toxicological sciences : an official journal of the Society of Toxicology20020401
Title: Stereochemistry of the peroxisomal branched-chain fatty acid alpha- and beta-oxidation systems in patients suffering from different peroxisomal disorders.
Journal: Journal of lipid research20020301
Title: Refsum's disease: a peroxisomal disorder affecting phytanic acid alpha-oxidation.
Journal: Journal of neurochemistry20020301
Title: Phytanic acid, a novel activator of uncoupling protein-1 gene transcription and brown adipocyte differentiation.
Journal: The Biochemical journal20020215
Title: [Refsum's disease: evolution 35 years after diagnosis].
Journal: Revue neurologique20020201
Title: Peroxisomal fatty acid oxidation and cellular redox.
Journal: Methods in enzymology20020101
Title: Effects of phytanic acid on the vitamin E status, lipid composition and physical properties of retinal cell membranes: implications for adult Refsum disease.
Journal: Clinical science (London, England : 1979)20011201
Title: Human metabolism of phytanic acid and pristanic acid.
Journal: Progress in lipid research20011101
Title: Refsum disease, peroxisomes and phytanic acid oxidation: a review.
Journal: Journal of neuropathology and experimental neurology20011101
Title: Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells.
Journal: Biochimica et biophysica acta20011031
Title: Studies on phytanoyl-CoA 2-hydroxylase and synthesis of phytanoyl-coenzyme A.
Journal: Bioorganic & medicinal chemistry letters20010917
Title: Refsum's disease.
Journal: QJM : monthly journal of the Association of Physicians20010801
Title: Identification of pristanal dehydrogenase activity in peroxisomes: conclusive evidence that the complete phytanic acid alpha-oxidation pathway is localized in peroxisomes.
Journal: Biochemical and biophysical research communications20010511
Title: [Refsum disease].
Journal: Nihon rinsho. Japanese journal of clinical medicine20010301
Title: The chlorophyll metabolite phytanic acid is a natural rexinoid--potential for treatment and prevention of diabetes.
Journal: Medical hypotheses20010201
Title: Normal and defective neuronal membranes: structure and function: neuronal lesions in peroxisomal disorders.
Journal: Journal of molecular neuroscience : MN20010101
Title: Pristanic acid and phytanic acid: naturally occurring ligands for the nuclear receptor peroxisome proliferator-activated receptor alpha.
Journal: Journal of lipid research20001101
Title: Phytanic acid is ligand and transcriptional activator of murine liver fatty acid binding protein.
Journal: Journal of lipid research19990401
Title: Phytanic acid is a retinoid X receptor ligand.
Journal: European journal of biochemistry19960215
