Title: HPLC with ultraviolet detection for the determination of chloroquine and desethylchloroquine in whole blood and finger-prick capillary blood dried on filter paper.
Journal: Journal of pharmaceutical and biomedical analysis 20110715
Title: Relationship between blood hydroxychloroquine and desethylchloroquine concentrations and cigarette smoking in treated patients with connective tissue diseases.
Journal: Annals of the rheumatic diseases 20071101
Title: Stereoselective determination of hydroxychloro-quine and its major metabolites in human urine by solid-phase microextraction and HPLC.
Journal: Journal of separation science 20071001
Title: Simultaneous determination of monodesethylchloroquine, chloroquine, cycloguanil and proguanil on dried blood spots by reverse-phase liquid chromatography.
Journal: Journal of pharmaceutical and biomedical analysis 20070219
Title: An improved high-performance liquid chromatographic determination of chloroquine and its major metabolite, desethylchloroquine, in human plasma.
Journal: European journal of drug metabolism and pharmacokinetics 20060101
Title: In vitro metabolism of chloroquine: identification of CYP2C8, CYP3A4, and CYP2D6 as the main isoforms catalyzing N-desethylchloroquine formation.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20030601
Title: Comparison of the in-vitro activity of amodiaquine and its main metabolite, monodesethyl-amodiaquine, in Plasmodium falciparum.
Journal: Wiener klinische Wochenschrift 20030101
Title: Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis.
Journal: Arthritis and rheumatism 20020601
Title: Application of higher throughput screening (HTS) inhibition assays to evaluate the interaction of antiparasitic drugs with cytochrome P450s.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010101
Title: Chloroquine treatment of severe malaria in children. Pharmacokinetics, toxicity, and new dosage recommendations.
Journal: The New England journal of medicine 19881208
Title: Ajayi FO, et al. Comparison of the partitioning in vitro of chloroquine and its desethyl metabolites between the erythrocytes and plasma of healthy subjects and those with falciparum malaria. Afr J Med Med Sci. 1989 Jun;18(2):95-100.
Title: Said A, et al. Chloroquine promotes IL-17 production by CD4+ T cells via p38-dependent IL-23 release by monocyte-derived Langerhans-like cells. J Immunol. 2014 Dec 15;193(12):6135-43.
Title: Vodicka P, et al. Assessment of chloroquine treatment for modulating autophagy flux in brain of WT and HD mice. J Huntingtons Dis. 2014;3(2):159-74.