149017-66-3,MFCD00153865
Catalog No.:AA00APRP

149017-66-3 | PPADS TETRASODIUM SALT

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
95%
in stock  
$131.00   $92.00
- +
10mg
95%
in stock  
$168.00   $118.00
- +
25mg
95%
in stock  
$306.00   $214.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00APRP
Chemical Name:
PPADS TETRASODIUM SALT
CAS Number:
149017-66-3
Molecular Formula:
C14H10N3Na4O12PS2
Molecular Weight:
599.3049
MDL Number:
MFCD00153865
SMILES:
O=Cc1c(COP(=O)(O[Na])O[Na])c(/N=N/c2ccc(cc2S(=O)(=O)O[Na])S(=O)(=O)O[Na])nc(c1O)C
Properties
Computed Properties
 
Complexity:
956  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
15  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-1.5  

Literature

Title: Pharmacology and structure of P2Y receptors.

Journal: Neuropharmacology 20160501

Title: Enhancement of dynein-mediated autophagosome trafficking and autophagy maturation by ROS in mouse coronary arterial myocytes.

Journal: Journal of cellular and molecular medicine 20141101

Title: Involvement of P2Y11 receptor in silica nanoparticles 30-induced IL-6 production by human keratinocytes.

Journal: Toxicology 20140801

Title: Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses.

Journal: Scientific reports 20120101

Title: Microglial zinc uptake via zinc transporters induces ATP release and the activation of microglia.

Journal: Glia 20111201

Title: Expression and functional characterization of P2X receptors in mouse alveolar macrophages.

Journal: Pflugers Archiv : European journal of physiology 20110901

Title: Spontaneous oscillations in intracellular Ca(2+) concentration via purinergic receptors elicit transient cell swelling in rat parotid ducts.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20091201

Title: Modulation of P2X receptors in dorsal root ganglion neurons of streptozotocin-induced diabetic neuropathy.

Journal: Neuroscience letters 20090313

Title: Development of selective agonists and antagonists of P2Y receptors.

Journal: Purinergic signalling 20090301

Title: Functional evidence for purinergic inhibitory neuromuscular transmission in the mouse internal anal sphincter.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080401

Title: Modulation of neurotransmitter release by P2X and P2Y receptors in the rat spinal cord.

Journal: Neuropharmacology 20080201

Title: Inhibitory purinergic transmission in mouse caecum: role for P2Y1 receptors as prejunctional modulators of ATP release.

Journal: Neuroscience 20071212

Title: Evidence that ATP or a related purine is an excitatory neurotransmitter in the longitudinal muscle of mouse distal colon.

Journal: British journal of pharmacology 20070501

Title: Prevention of liver fibrosis by the purinoceptor antagonist pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS).

Journal: In vivo (Athens, Greece) 20070101

Title: P2X7 receptor inhibition improves recovery after spinal cord injury.

Journal: Nature medicine 20040801

Title: Pharmacological and signaling properties of endogenous P2Y1 receptors in cystic fibrosis transmembrane conductance regulator-expressing Chinese hamster ovary cells.

Journal: The Journal of pharmacology and experimental therapeutics 20040501

Title: Pharmacological characterization of the human P2Y13 receptor.

Journal: Molecular pharmacology 20030701

Title: Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist.

Journal: Molecular pharmacology 20021101

Title: Purinergic and adrenergic agonists synergize in stimulating vasopressin and oxytocin release.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20001201

Title: Pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS), a putative P2Y(1) receptor antagonist, blocks signaling at a site distal to the receptor in Madin-Darby canine kidney-D(1) cells.

Journal: The Journal of pharmacology and experimental therapeutics 20000101

Title: Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice.

Journal: British journal of pharmacology 19991201

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 149017-66-3
Historical Records
Tags:149017-66-3 Molecular Formula|149017-66-3 MDL|149017-66-3 SMILES|149017-66-3 PPADS TETRASODIUM SALT
Catalog No.: AA00APRP
149017-66-3,MFCD00153865
149017-66-3 | PPADS TETRASODIUM SALT
Pack Size: 5mg
Purity: 95%
in stock
$131.00 $92.00
Pack Size: 10mg
Purity: 95%
in stock
$168.00 $118.00
Pack Size: 25mg
Purity: 95%
in stock
$306.00 $214.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00APRP
Chemical Name: PPADS TETRASODIUM SALT
CAS Number: 149017-66-3
Molecular Formula: C14H10N3Na4O12PS2
Molecular Weight: 599.3049
MDL Number: MFCD00153865
SMILES: O=Cc1c(COP(=O)(O[Na])O[Na])c(/N=N/c2ccc(cc2S(=O)(=O)O[Na])S(=O)(=O)O[Na])nc(c1O)C
Properties
Complexity: 956  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 32  
Hydrogen Bond Acceptor Count: 15  
Hydrogen Bond Donor Count: 5  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -1.5  
Literature fold

Title: Pharmacology and structure of P2Y receptors.

Journal: Neuropharmacology20160501

Title: Enhancement of dynein-mediated autophagosome trafficking and autophagy maturation by ROS in mouse coronary arterial myocytes.

Journal: Journal of cellular and molecular medicine20141101

Title: Involvement of P2Y11 receptor in silica nanoparticles 30-induced IL-6 production by human keratinocytes.

Journal: Toxicology20140801

Title: Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses.

Journal: Scientific reports20120101

Title: Microglial zinc uptake via zinc transporters induces ATP release and the activation of microglia.

Journal: Glia20111201

Title: Expression and functional characterization of P2X receptors in mouse alveolar macrophages.

Journal: Pflugers Archiv : European journal of physiology20110901

Title: Spontaneous oscillations in intracellular Ca(2+) concentration via purinergic receptors elicit transient cell swelling in rat parotid ducts.

Journal: American journal of physiology. Gastrointestinal and liver physiology20091201

Title: Modulation of P2X receptors in dorsal root ganglion neurons of streptozotocin-induced diabetic neuropathy.

Journal: Neuroscience letters20090313

Title: Development of selective agonists and antagonists of P2Y receptors.

Journal: Purinergic signalling20090301

Title: Functional evidence for purinergic inhibitory neuromuscular transmission in the mouse internal anal sphincter.

Journal: American journal of physiology. Gastrointestinal and liver physiology20080401

Title: Modulation of neurotransmitter release by P2X and P2Y receptors in the rat spinal cord.

Journal: Neuropharmacology20080201

Title: Inhibitory purinergic transmission in mouse caecum: role for P2Y1 receptors as prejunctional modulators of ATP release.

Journal: Neuroscience20071212

Title: Evidence that ATP or a related purine is an excitatory neurotransmitter in the longitudinal muscle of mouse distal colon.

Journal: British journal of pharmacology20070501

Title: Prevention of liver fibrosis by the purinoceptor antagonist pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS).

Journal: In vivo (Athens, Greece)20070101

Title: P2X7 receptor inhibition improves recovery after spinal cord injury.

Journal: Nature medicine20040801

Title: Pharmacological and signaling properties of endogenous P2Y1 receptors in cystic fibrosis transmembrane conductance regulator-expressing Chinese hamster ovary cells.

Journal: The Journal of pharmacology and experimental therapeutics20040501

Title: Pharmacological characterization of the human P2Y13 receptor.

Journal: Molecular pharmacology20030701

Title: Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist.

Journal: Molecular pharmacology20021101

Title: Purinergic and adrenergic agonists synergize in stimulating vasopressin and oxytocin release.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20001201

Title: Pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS), a putative P2Y(1) receptor antagonist, blocks signaling at a site distal to the receptor in Madin-Darby canine kidney-D(1) cells.

Journal: The Journal of pharmacology and experimental therapeutics20000101

Title: Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice.

Journal: British journal of pharmacology19991201

Building Blocks More >
178557-21-6
178557-21-6
1-(8-Bromo-2,3,6,7-tetrahydrobenzodifuran-4-yl)-2-aminoethane hydrochloride
AA00AQAF | MFCD09751142
168100-28-5
168100-28-5
4-(4-Carboxy-3-fluorophenyl)phenol
AA00AQFO | MFCD18312931
15965-32-9
15965-32-9
2,5-Dichloro-4-nitro-1H-imidazole
AA00AQLM | MFCD00748952
1451393-27-3
1451393-27-3
5-Bromo-3-chloro-2-fluorophenylboronic acid
AA00AR2A | MFCD12026726
1705578-40-0
1705578-40-0
potassium ((cyclopentylamino)methyl)trifluoroborate
AA00ARPK | MFCD18714999
185423-66-9
185423-66-9
3-(Methylsulfonyl)-6-oxa-3-azabicyclo[3.1.0]hexane
AA00AS5F | MFCD11040508
18620-64-9
18620-64-9
5-Chloropyrimidine-2,4-diamine
AA00ASPD | MFCD09907877
1807537-31-0
1807537-31-0
Benzyl-peg6-ch2co2tbu
AA00AT6I | MFCD28142466
1852497-07-4
1852497-07-4
(4-(4-Amino-3-methylphenyl)piperidin-1-yl)(cyclopropyl)methanone
AA00ATDQ | MFCD30530548
176-73-8
176-73-8
7-Azaspiro[4.5]decane
AA00AVR7 | MFCD03175394
Submit
© 2017 AA BLOCKS, INC. All rights reserved.