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192575-19-2,MFCD00153865
Catalog No.:AA01CC6R

192575-19-2 | PPADS Tetrasodium

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥95%
in stock  
$63.00   $44.00
- +
50mg
≥95%
in stock  
$262.00   $183.00
- +
250mg
≥95%
in stock  
$1,138.00   $796.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01CC6R
Chemical Name:
PPADS Tetrasodium
CAS Number:
192575-19-2
Molecular Formula:
C14H10N3Na4O12PS2
Molecular Weight:
599.3049
MDL Number:
MFCD00153865
SMILES:
O=Cc1c(COP(=O)([O-])[O-])c(/N=N/c2ccc(cc2S(=O)(=O)[O-])S(=O)(=O)[O-])nc(c1O)C.[Na+].[Na+].[Na+].[Na+]
Properties
Computed Properties
 
Complexity:
918  
Covalently-Bonded Unit Count:
5  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
15  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  

Literature

Title: Flores-Soto E, et al. PPADS, a P2X receptor antagonist, as a novel inhibitor of the reverse mode of the Na⁺/Ca²⁺ exchanger in guinea pig airway smooth muscle. Eur J Pharmacol. 2012 Jan 15;674(2-3):439-44.

Title: Huo H, et al. Mapping the binding site of the P2X receptor antagonist PPADS reveals the importance of orthosteric site charge and the cysteine-rich head region. J Biol Chem. 2018 Aug 17;293(33):12820-12831.

Title: Einfluss von ATP und seinen Derivaten auf die Aktivierung von Monozyten.

Title: Rost S, et al. P2 receptor antagonist PPADS inhibits mesangial cell proliferation in experimental mesangialproliferative glomerulonephritis. Kidney Int. 2002 Nov;62(5):1659-71.

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Tags:192575-19-2 Molecular Formula|192575-19-2 MDL|192575-19-2 SMILES|192575-19-2 PPADS Tetrasodium