Home Fluorides 149301-79-1
149301-79-1,MFCD00236427
Catalog No.:AA001LHA

149301-79-1 | 6,9,12,15-Heneicosatetraen-2-one, 1,1,1-trifluoro-, (6Z,9Z,12Z,15Z)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$90.00   $63.00
- +
10mg
≥98%
in stock  
$153.00   $107.00
- +
50mg
≥98%
in stock  
$619.00   $433.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001LHA
Chemical Name:
6,9,12,15-Heneicosatetraen-2-one, 1,1,1-trifluoro-, (6Z,9Z,12Z,15Z)-
CAS Number:
149301-79-1
Molecular Formula:
C21H31F3O
Molecular Weight:
356.4654
MDL Number:
MFCD00236427
SMILES:
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)C(F)(F)F
Properties
Computed Properties
 
Complexity:
443  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
4  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
14  
XLogP3:
7.6  

Literature

Title: Tudor staphylococcal nuclease drives chemoresistance of non-small cell lung carcinoma cells by regulating S100A11.

Journal: Oncotarget 20150520

Title: Inhibition of cytosolic phospholipase A(2) alpha protects against focal ischemic brain damage in mice.

Journal: Brain research 20120830

Title: Involvement of protein kinase A activation and phospholipase A(2) inhibition in the adenosine-activated basolateral 50 pS K(+) channels in the thick ascending limb of the rat kidney.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20120825

Title: Cysteinyl leukotrienes mediate the response of submucosal ganglia from rat colon to bradykinin.

Journal: European journal of pharmacology 20120415

Title: Stimulation of Ca2+-sensing receptor inhibits the basolateral 50-pS K channels in the thick ascending limb of rat kidney.

Journal: Biochimica et biophysica acta 20120201

Title: Arachidonyl trifluoromethyl ketone ameliorates experimental autoimmune encephalomyelitis via blocking peroxynitrite formation in mouse spinal cord white matter.

Journal: Experimental neurology 20110901

Title: Cytosolic phospholipase A2 as a molecular target for the radiosensitization of ovarian cancer.

Journal: Cancer letters 20110528

Title: Stimulation of A(₂a) adenosine receptor abolishes the inhibitory effect of arachidonic acid on the basolateral 50-pS K channel in the thick ascending limb.

Journal: American journal of physiology. Renal physiology 20110401

Title: Structure-activity relationship studies on 1-(5-carboxyindol-1-yl)-propan-2-one inhibitors of human cytosolic phospholipase A2α: variation of the activated ketone moiety.

Journal: Bioorganic & medicinal chemistry letters 20110315

Title: Delayed production of arachidonic acid contributes to the delay of proteinase-activated receptor-1 (PAR1)-triggered prostaglandin E2 release in rat gastric epithelial RGM1 cells.

Journal: Journal of cellular biochemistry 20110301

Title: COX-2 inhibition and inhibition of cytosolic phospholipase A2 increase CD36 expression and foam cell formation in THP-1 cells.

Journal: Lipids 20110201

Title: Peroxisome proliferation activation receptor alpha modulation of Ca2+-regulated exocytosis via arachidonic acid in guinea-pig antral mucous cells.

Journal: Experimental physiology 20100801

Title: TLR4-dependent induction of vascular adhesion molecule-1 in rheumatoid arthritis synovial fibroblasts: Roles of cytosolic phospholipase A(2)alpha/cyclooxygenase-2.

Journal: Journal of cellular physiology 20100501

Title: Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain.

Journal: The Journal of pharmacology and experimental therapeutics 20100501

Title: Nanomolar vitamin E alpha-tocotrienol inhibits glutamate-induced activation of phospholipase A2 and causes neuroprotection.

Journal: Journal of neurochemistry 20100301

Title: 1-Indol-1-yl-propan-2-ones and related heterocyclic compounds as dual inhibitors of cytosolic phospholipase A(2)alpha and fatty acid amide hydrolase.

Journal: Bioorganic & medicinal chemistry 20100115

Title: Cytosolic phospholipase A2alpha mediates Pseudomonas aeruginosa LPS-induced airway constriction of CFTR -/- mice.

Journal: Respiratory research 20100101

Title: Mechanism underlying endothelium-dependent relaxation by 2-methylthio-ADP in monkey cerebral artery.

Journal: Journal of pharmacological sciences 20100101

Title: Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors.

Journal: Journal of medicinal chemistry 20091210

Title: Group IVA phospholipase A(2) activity may mediate prostaglandin F(2alpha)-induced luteal regression in pseudopregnant rats.

Journal: Prostaglandins & other lipid mediators 20091201

Title: Bis(dialkylaminethiocarbonyl)disulfides as potent and selective monoglyceride lipase inhibitors.

Journal: Journal of medicinal chemistry 20091126

Title: Arachidonic acid: a key molecule for astrocyte survival to peroxynitrite.

Journal: Glia 20091115

Title: Arachidonyl trifluoromethyl ketone is neuroprotective after spinal cord injury.

Journal: Journal of neurotrauma 20090801

Title: Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages.

Journal: Chemosphere 20090301

Title: Cytosolic phospholipase A2: targeting cancer through the tumor vasculature.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090301

Title: Significance of the nongenomic, inflammatory pathway in mediating the toxic action of TCDD to induce rapid and long-term cellular responses in 3T3-L1 adipocytes.

Journal: Biochemistry 20081230

Title: Initial and extended inflammatory messages of the nongenomic signaling pathway of the TCDD-activated Ah receptor in U937 macrophages.

Journal: Archives of biochemistry and biophysics 20081215

Title: Ca2+-independent PLA2 controls endothelial store-operated Ca2+ entry and vascular tone in intact aorta.

Journal: American journal of physiology. Heart and circulatory physiology 20081201

Title: Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain.

Journal: Journal of neurochemistry 20081201

Title: Inhibition of cyclooxygenases 1 and 2 by the phospholipase-blocker, arachidonyl trifluoromethyl ketone.

Journal: British journal of pharmacology 20081101

Title: Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.

Journal: Nature neuroscience 20081101

Title: Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA).

Journal: The Journal of biological chemistry 20080912

Title: [Suppression of cell proliferation by inhibitors to redox signaling in human lens epithelial cells].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20080701

Title: Tumour necrosis factor alpha upregulates platelet CD40L in patients with heart failure.

Journal: Cardiovascular research 20080601

Title: Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin-induced smooth muscle cell proliferation.

Journal: American journal of physiology. Cell physiology 20080601

Title: Cytochrome P-450 metabolites of 2-arachidonoylglycerol play a role in Ca2+-induced relaxation of rat mesenteric arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20080501

Title: Cytosolic phospholipase A2 and arachidonic acid metabolites modulate ventilator-induced permeability increases in isolated mouse lungs.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20080201

Title: Evidence that PAR2-triggered prostaglandin E2 (PGE2) formation involves the ERK-cytosolic phospholipase A2-COX-1-microsomal PGE synthase-1 cascade in human lung epithelial cells.

Journal: Cell biochemistry and function 20080101

Title: Arachidonic acid as a retrograde signal controlling growth and dynamics of retinotectal arbors.

Journal: Developmental neurobiology 20080101

Title: STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080101

Title: Involvement of cPLA2 inhibition in dexamethasone-induced thymocyte apoptosis.

Journal: International journal of immunopathology and pharmacology 20080101

Title: Role of phospholipase A2 (group I secreted) in the genesis of basal tone in the internal anal sphincter smooth muscle.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20071101

Title: Arachidonic acid signaling is involved in the mechanism of imidazoline-induced KATP channel-independent stimulation of insulin secretion.

Journal: Cellular and molecular life sciences : CMLS 20071101

Title: A novel role of group VIB calcium-independent phospholipase A2 (iPLA2gamma) in the inducible expression of group IIA secretory PLA2 in rat fibroblastic cells.

Journal: The Journal of biological chemistry 20070713

Title: Apoptosis is mediated by cytosolic phospholipase A2 during simulated ischaemia/reperfusion-induced injury in neonatal cardiac myocytes.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20070701

Title: Regulation of luteal prostaglandin F(2 alpha) production and its relevance to cell death: an in vitro study using rat dispersed luteal cells.

Journal: Prostaglandins & other lipid mediators 20070601

Title: 1-(5-Carboxy- and 5-carbamoylindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha: bioisosteric replacement of the carboxylic acid and carboxamide moiety.

Journal: Bioorganic & medicinal chemistry 20070415

Title: Effects of arachidonate metabolism inhibitors on basal and human chorionic gonadotropin-stimulated progesterone secretion by rat corpus luteum cells in vitro.

Journal: Prostaglandins & other lipid mediators 20070201

Title: Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells.

Journal: Molecular and cellular biochemistry 20070101

Title: Cytosolic PLA2 in zymogen granule fusion and amylase release: inhibition of GTP-induced fusion by arachidonyl trifluoromethyl ketone points to cPLA2 in G-protein-mediated secretory vesicle fusion.

Journal: Journal of biochemistry 20070101

Title: The role of arachidonic acid and its metabolites in insulin secretion from human islets of langerhans.

Journal: Diabetes 20070101

Title: Amyloid beta enhances cytosolic phospholipase A2 level and arachidonic acid release via nitric oxide in APP-transfected PC12 cells.

Journal: Acta biochimica Polonica 20070101

Title: Phospholipase A2 activation regulates cytotoxicity of methylmercury in vascular endothelial cells.

Journal: International journal of toxicology 20070101

Title: Cytosolic phospholipase A alpha modulates NMDA neurotoxicity in mouse hippocampal cultures.

Journal: The European journal of neuroscience 20061201

Title: Effects of pyrrophenone, an inhibitor of group IVA phospholipase A2, on eicosanoid and PAF biosynthesis in human neutrophils.

Journal: British journal of pharmacology 20061001

Title: Pro-atherogenic effect of interleukin-4 in endothelial cells: modulation of oxidative stress, nitric oxide and monocyte chemoattractant protein-1 expression.

Journal: Atherosclerosis 20060801

Title: Cytosolic phospholipase A2 inhibition attenuates ischemia-reperfusion injury in an isolated rat lung model.

Journal: Transplantation 20060627

Title: Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice.

Journal: European journal of pharmacology 20060613

Title: Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration, and invasion of ovarian cancer cells.

Journal: Cancer research 20060315

Title: Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor.

Journal: British journal of pharmacology 20060301

Title: Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human colorectal cancer cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060201

Title: The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium.

Journal: The Journal of physiology 20060101

Title: Enhancement of Ca2+-regulated exocytosis by indomethacin in guinea-pig antral mucous cells: arachidonic acid accumulation.

Journal: Experimental physiology 20060101

Title: A novel role for calcium-independent phospholipase A in alpha-amino-3-hydroxy-5-methylisoxazole-propionate receptor regulation during long-term potentiation.

Journal: The European journal of neuroscience 20060101

Title: Effects of cannabinoids on the anxiety-like response in mice.

Journal: Pharmacological reports : PR 20060101

Title: Phosphorylation of AMPA receptor subunits is differentially regulated by phospholipase A2 inhibitors.

Journal: Neuroscience letters 20051125

Title: Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050915

Title: The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications.

Journal: Journal of medicinal chemistry 20050811

Title: Leptin rapidly activates PPARs in C2C12 muscle cells.

Journal: Biochemical and biophysical research communications 20050708

Title: Vitamin C inhibits platelet expression of CD40 ligand.

Journal: Free radical biology & medicine 20050615

Title: Activation of BK channels in GH3 cells by a c-PLA2-dependent G-protein signaling pathway.

Journal: Journal of neurophysiology 20050601

Title: Clara cell secretory protein and phospholipase A2 activity modulate acute ventilator-induced lung injury in mice.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20050401

Title: Oxidant-mediated activation of cytosolic phospholipase a(2) in pulmonary endothelium: role of protein kinase C alpha and a pertussis toxin-sensitive protein.

Journal: Endothelium : journal of endothelial cell research 20050101

Title: Group IIA secretory phospholipase A2 is a unique 12/15-lipoxygenase-regulated gene in cytokine-stimulated rat fibroblastic 3Y1 cells.

Journal: Biochimica et biophysica acta 20041108

Title: Amyloid beta(1-42) and its beta(25-35) fragment induce activation and membrane translocation of cytosolic phospholipase A2 in bovine retina capillary pericytes.

Journal: Biochimica et biophysica acta 20041108

Title: Intracerebroventricular injection of phospholipases A2 inhibitors modulates allodynia after facial carrageenan injection in mice.

Journal: Pain 20041101

Title: Mitochondrial dysfunction is a primary event in renal cell oxalate toxicity.

Journal: Kidney international 20041101

Title: Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons.

Journal: European journal of pharmacology 20040913

Title: gp91phox-dependent expression of platelet CD40 ligand.

Journal: Circulation 20040907

Title: Release of choline in the isolated heart, an indicator of ischemic phospholipid degradation and its protection by ischemic preconditioning: no evidence for a role of phospholipase D.

Journal: Life sciences 20040813

Title: Identifying pathways involved in leptin-dependent aggregation of human platelets.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040801

Title: Comparison of cellular mechanisms underlying histamine release from rat mast cells induced by ionic and nonionic radiographic contrast media.

Journal: Investigative radiology 20040801

Title: Prolonged extracellular signal-regulated kinase 1/2 activation during fibroblast growth factor 1- or heregulin beta1-induced antiestrogen-resistant growth of breast cancer cells is resistant to mitogen-activated protein/extracellular regulated kinase kinase inhibitors.

Journal: Cancer research 20040701

Title: Role of an aprotinin-sensitive protease in protein kinase Calpha-mediated activation of cytosolic phospholipase A2 by calcium ionophore (A23187) in pulmonary endothelium.

Journal: Cellular signalling 20040601

Title: Hypoxia activates matrix metalloproteinase expression and the VEGF system in monkey choroid-retinal endothelial cells: Involvement of cytosolic phospholipase A2 activity.

Journal: Molecular vision 20040517

Title: Mercury- and copper-induced lysosomal membrane destabilisation depends on [Ca2+]i dependent phospholipase A2 activation.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040210

Title: Cytosolic phospholipase A2 plays a key role in the pathogenesis of multiple sclerosis-like disease.

Journal: Neuron 20040205

Title: Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.

Journal: Free radical biology & medicine 20031201

Title: Prostacyclin production in rat aortic smooth muscle cells: role of protein kinase C, phospholipase D and cyclooxygenase-2 expression.

Journal: Cardiovascular research 20031101

Title: Phospholipase A2 plays an important role in myelin breakdown and phagocytosis during Wallerian degeneration.

Journal: Molecular and cellular neurosciences 20031101

Title: 17Beta-eEstradiol stimulates arachidonate release from human amnion-like WISH cells through a rapid mechanism involving a membrane receptor.

Journal: Endocrinology 20030801

Title: A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice.

Journal: American journal of physiology. Lung cellular and molecular physiology 20030501

Title: Resveratrol activates adenylyl-cyclase in human breast cancer cells: a novel, estrogen receptor-independent cytostatic mechanism.

Journal: Carcinogenesis 20030501

Title: Neuronal damage by secretory phospholipase A2: modulation by cytosolic phospholipase A2, platelet-activating factor, and cyclooxygenase-2 in neuronal cells in culture.

Journal: Neuroscience letters 20030227

Title: Methylmercury-induced reactive oxygen species formation in neonatal cerebral astrocytic cultures is attenuated by antioxidants.

Journal: Brain research. Molecular brain research 20030131

Title: Phospholipase A2 modulates respiratory burst developed by neutrophils in patients with rheumatoid arthritis.

Journal: Journal of cellular and molecular medicine 20030101

Title: Endothelial NADPH oxidase: mechanism of activation by low-density lipoprotein.

Journal: Endothelium : journal of endothelial cell research 20030101

Title: Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death.

Journal: Cell death and differentiation 20021201

Title: Essential role of Ca2+ -dependent phospholipase A2 in estradiol-induced lysosome activation.

Journal: American journal of physiology. Cell physiology 20021101

Title: Role of cytoplasmic phospholipase A2 in endothelium-derived hyperpolarizing factor dilations of rat middle cerebral arteries.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20021001

Title: Involvement of GD3 in platelet activation. A novel association with Fcgamma receptor.

Journal: Biochimica et biophysica acta 20020808

Title: Endothelin-1-induced arachidonic acid release by cytosolic phospholipase A2 activation in rat vascular smooth muscle via extracellular signal-regulated kinases pathway.

Journal: Biochemical pharmacology 20020801

Title: Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils. Evidence for different arachidonate pools.

Journal: European journal of biochemistry 20020801

Title: Involvement of oxidative stress in bee venom-induced inhibition of Na+/glucose cotransporter in renal proximal tubule cells.

Journal: Clinical and experimental pharmacology & physiology 20020701

Title: Dopamine D(2) receptor-induced COX-2-mediated production of prostaglandin E(2) in D(2)-transfected Chinese hamster ovary cells without simultaneous administration of a Ca(2+)-mobilizing agent.

Journal: Biochemical pharmacology 20020615

Title: Implication of three isoforms of PLA(2) in human T-cell proliferation.

Journal: FEBS letters 20020605

Title: Phosphatidylinositide 3-kinase regulates angiotensin II-induced cytosolic phospholipase A2 activity and growth in vascular smooth muscle cells.

Journal: Archives of biochemistry and biophysics 20020601

Title: Role of p38 MAPK in the regulation of apoptosis signaling induced by TNF-alpha in differentiated PC12 cells.

Journal: Journal of biochemistry and molecular biology 20020531

Title: Voltage independence of vasomotion in isolated irideal arterioles of the rat.

Journal: The Journal of physiology 20020401

Title: Determination of the cell lytic properties of amphiphilic inhibitors of the cytosolic phospholipase A2 against human platelets by measuring the liberation of serotonin with high-performance liquid chromatography and fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020325

Title: Design and synthesis of a novel and potent series of inhibitors of cytosolic phospholipase A(2) based on a 1,3-disubstituted propan-2-one skeleton.

Journal: Journal of medicinal chemistry 20020314

Title: Possible implication of Golgi-nucleating function for the centrosome.

Journal: Biochemical and biophysical research communications 20020301

Title: 4-Bromophenacyl bromide induces Ca2+ influx in human gingival fibroblasts.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020301

Title: Mechanisms of glutamate release in the rat spinal cord slices during metabolic inhibition.

Journal: Journal of neurotrauma 20020201

Title: Identification of the phospholipase A(2) isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: limits of phospholipase A(2) inhibitors.

Journal: Biochemical pharmacology 20020115

Title: The central role of thromboxane and platelet activating factor receptors in ex vivo regulation of endotoxin-induced monocyte tissue factor activity in human whole blood.

Journal: Journal of endotoxin research 20020101

Title: Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice.

Journal: The Journal of investigative dermatology 20011201

Title: Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium.

Journal: American journal of physiology. Cell physiology 20011001

Title: Arachidonate metabolism and the signaling pathway of induction of apoptosis by oxidized LDL/oxysterol.

Journal: Journal of lipid research 20011001

Title: Differential role of cytosolic phospholipase A2 in the invasion of brain microvascular endothelial cells by Escherichia coli and Listeria monocytogenes.

Journal: The Journal of infectious diseases 20010915

Title: Calcium-independent phospholipase A(2) is required for human monocyte chemotaxis to monocyte chemoattractant protein 1.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010915

Title: Platelet-derived growth factor stimulates phospholipase C-gamma 1, extracellular signal-regulated kinase, and arachidonic acid release in rat myometrial cells: contribution to cyclic 3',5'-adenosine monophosphate production and effect on cell proliferation.

Journal: Biology of reproduction 20010801

Title: Effects of phospholipase A(2) activating peptides upon GTP-binding protein-evoked adrenocorticotrophin secretion.

Journal: European journal of pharmacology 20010727

Title: Role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha.

Journal: Reproduction (Cambridge, England) 20010701

Title: Fatty acids inhibit anion secretion in rat colon: apical and basolateral action sites.

Journal: Pflugers Archiv : European journal of physiology 20010701

Title: Angiotensin receptor blocker losartan suppresses platelet activity by interfering with thromboxane signaling.

Journal: Cardiovascular drugs and therapy 20010701

Title: Tumor necrosis factor-alpha selectively induces MnSOD expression via mitochondria-to-nucleus signaling, whereas interleukin-1beta utilizes an alternative pathway.

Journal: The Journal of biological chemistry 20010608

Title: Platelet activating factor increases ciliary activity in the hamster oviduct through epithelial production of prostaglandin E2.

Journal: Pflugers Archiv : European journal of physiology 20010601

Title: Arachidonic acid modulates the spatiotemporal characteristics of agonist-evoked Ca2+ waves in mouse pancreatic acinar cells.

Journal: The Journal of biological chemistry 20010518

Title: The Ca2+-sensing receptor activates cytosolic phospholipase A2 via a Gqalpha -dependent ERK-independent pathway.

Journal: The Journal of biological chemistry 20010427

Title: Docosahexaenoic acid improves long-term potentiation attenuated by phospholipase A(2) inhibitor in rat hippocampal slices.

Journal: British journal of pharmacology 20010401

Title: Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.

Journal: Journal of leukocyte biology 20010401

Title: Stimulative effect of cadmium on prostaglandin E2 production in primary mouse osteoblastic cells.

Journal: Calcified tissue international 20010301

Title: Pyrrolidine inhibitors of human cytosolic phospholipase A2. Part 2: synthesis of potent and crystallized 4-triphenylmethylthio derivative 'pyrrophenone'.

Journal: Bioorganic & medicinal chemistry letters 20010226

Title: Arachidonyltrifluoromethy ketone, a phospholipase A(2) antagonist, induces dispersal of both Golgi stack- and trans Golgi network-resident proteins throughout the cytoplasm.

Journal: Biochemical and biophysical research communications 20010223

Title: Arachidonyl trifluoromethyl ketone induces lipid body formation in leukocytes.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20010101

Title: Riendeau D, et al. Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. J Biol Chem. 1994;269(22):15619-15624.

Title: Schanstra JP, et al. Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment. JCI Insight. 2019;4(10):e125638. Published 2019 May 16.

Title: Loweth AC, et al. A specific inhibitor of cytosolic phospholipase A2 activity, AACOCF3, inhibits glucose-induced insulin secretion from isolated rat islets. Biochem Biophys Res Commun. 1996;218(2):423-427.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 149301-79-1
Tags:149301-79-1 Molecular Formula|149301-79-1 MDL|149301-79-1 SMILES|149301-79-1 6,9,12,15-Heneicosatetraen-2-one, 1,1,1-trifluoro-, (6Z,9Z,12Z,15Z)-