Home Amines 1494-85-5
1494-85-5,MFCD01016124
Catalog No.:AA001LLL

1494-85-5 | 4-Amino-n-(4-fluorophenyl)benzenesulfonamide

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100mg
97%
in stock  
$32.00   $22.00
- +
250mg
97%
in stock  
$41.00   $29.00
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1g
97%
in stock  
$87.00   $61.00
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5g
97%
in stock  
$320.00   $224.00
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25g
98%
in stock  
$1,407.00   $985.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001LLL
Chemical Name:
4-Amino-n-(4-fluorophenyl)benzenesulfonamide
CAS Number:
1494-85-5
Molecular Formula:
C12H11FN2O2S
Molecular Weight:
266.2913
MDL Number:
MFCD01016124
SMILES:
Nc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)F
Properties
Computed Properties
 
Complexity:
353  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
2.2  

Downstream Synthesis Route

[1]Bradlow;VanderWerf[JournaloftheAmericanChemicalSociety,1948,vol.70,p.654,656]

[1]Bradlow;VanderWerf[JournaloftheAmericanChemicalSociety,1948,vol.70,p.654]

[1]Wang,Xu;Ahn,Yong-Mo;Lentscher,AdamG.;Lister,JuliaS.;Brothers,RobertC.;Kneen,MaleaM.;Gerratana,Barbara;Boshoff,HelenaI.;Dowd,CynthiaS.[BioorganicandMedicinalChemistryLetters,2017,vol.27,#18,p.4426-4430]

[2]Silveira,FláviaF.;deSouza,JulianaO.;Hoelz,LucasV.B.;Campos,ViníciusR.;Jabor,ValquíriaA.P.;Aguiar,AnnaC.C.;Nonato,M.Cristina;Albuquerque,MagalyG.;Guido,RafaelV.C.;Boechat,Nubia;Pinheiro,LuizC.S.[EuropeanJournalofMedicinalChemistry,2021,vol.209]

[3]Hager;Starkey;Chapman[JournaloftheAmericanPharmaceuticalAssociation(1912),1941,vol.30,p.65,66]

[4]Wang,Peng;Liu,Chuan;Sanches,Tino;Zhong,Yuan;Liu,Bo;Xiong,Junlong;Neamati,Nouri;Zhao,Guisen[BioorganicandMedicinalChemistryLetters,2009,vol.19,#16,p.4574-4578]

[5]Yu,Shenghui;Zhang,Linna;Yan,Shifeng;Wang,Peng;Sanchez,Tino;Christ,Frauke;Debyser,Zeger;Neamati,Nouri;Zhao,Guisen[JournalofEnzymeInhibitionandMedicinalChemistry,2012,vol.27,#5,p.628-640]

[6]Zhang,Guangtao;Plotnikov,AlexanderN.;Rusinova,Elena;Shen,Tong;Morohashi,Keita;Joshua,Jennifer;Zeng,Lei;Mujtaba,Shiraz;Ohlmeyer,Michael;Zhou,Ming-Ming[JournalofMedicinalChemistry,2013,vol.56,#22,p.9251-9264]

[7]Marwaha,Sania;Uvell,Hanna;Salin,Olli;Lindgren,AndersE.G.;Silver,Jim;Elofsson,Mikael;Gylfe,Åsa[AntimicrobialAgentsandChemotherapy,2014,vol.58,#5,p.2968-2971]

[8]SunilKumar;Kudva,Jyothi;Lahtinen,Manu;Peuronen,Anssi;Sadashiva,Rajitha;Naral,Damodara[JournalofMolecularStructure,2019,vol.1190,p.29-36]

[1]Suter;Weston[JournaloftheAmericanChemicalSociety,1940,vol.62,p.604]

Literature

Title: Analgesic agents without gastric damage: design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selective inhibitors.

Journal: Bioorganic & medicinal chemistry 20070115

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