Catalog No.:AA00ABFB

1499193-61-1 | 5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 6-[2-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl] 5-(1,1-diMethylethyl) ester, (6S)-

Name: Name:5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 6-[2-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl] 5-(1,1-diMethylethyl) ester, (6S)-
Brand: AABLOCKS
SKU: AA00ABFB
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100mg

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250mg

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Technical Information
Properties
Downstream Synthesis Route
Literature
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA00ABFB

Chemical Name:

5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 6-[2-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl] 5-(1,1-diMethylethyl) ester, (6S)-

CAS Number:

1499193-61-1

Molecular Formula:

C27H26BrF2NO5

Molecular Weight:

562.3998

MDL Number:

MFCD28386930

SMILES:

O=C([C@@H]1CC2(CN1C(=O)OC(C)(C)C)CC2)OCC(=O)c1ccc2c(c1)C(F)(F)c1c2ccc(c1)Br

Properties

Downstream Synthesis Route

123348-27-6

(S)-6-(2-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl)5-tert-butyl5-azaspiro2.4heptane-5,6-dicarboxylate

[1]Patent:US2013/324740,2013,A1

[2]Patent:US2013/324496,2013,A1

[3]JournalofMedicinalChemistry,2014,vol.57,p.2033-2046

[4]Patent:CN106117187,2016,A

[5]Patent:CN107954990,2018,A

1499193-61-1

1441670-89-8

[1]CurrentPatentAssignee:XIAMENCITYWEIJIACHEMICALTECHNOLOGY-CN105237516,2016,ALocationinpatent:Paragraph0037;0036;0038;0039

[2]CurrentPatentAssignee:GILEADSCIENCESINC-US2013/324740,2013,A1Locationinpatent:Paragraph0219;0220

[3]Link,JohnO.;Taylor,JamesG.;Xu,Lianhong;Mitchell,Michael;Guo,Hongyan;Liu,Hongtao;Kato,Darryl;Kirschberg,Thorsten;Sun,Jianyu;Squires,Neil;Parrish,Jay;Keller,Terry;Yang,Zheng-Yu;Yang,Chris;Matles,Mike;Wang,Yujin;Wang,Kelly;Cheng,Guofeng;Tian,Yang;Mogalian,Erik;Mondou,Elsa;Cornpropst,Melanie;Perry,Jason;Desai,ManojC.[JournalofMedicinalChemistry,2014,vol.57,#5,p.2033-2046]

[4]CurrentPatentAssignee:SHENZHENTARGETRXINC-CN106117187,2016,ALocationinpatent:Paragraph0066;0067

[5]CurrentPatentAssignee:ANHUINUOQUANPHARMACEUTICAL-CN107954990,2018,ALocationinpatent:Paragraph0122;0124;0125;0195;0264

1499193-61-1

CASUnavailable

1441670-89-8

[1]CurrentPatentAssignee:GILEADSCIENCESINC-US2013/324496,2013,A1Locationinpatent:Paragraph0248-0249

Literature

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SDS