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150-25-4,MFCD00004295
Catalog No.:AA001M4P

150-25-4 | Bicine

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10g
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25g
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500g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001M4P
Chemical Name:
Bicine
CAS Number:
150-25-4
Molecular Formula:
C6H13NO4
Molecular Weight:
163.1717
MDL Number:
MFCD00004295
SMILES:
OCCN(CC(=O)O)CCO
Properties
Computed Properties
 
Complexity:
111  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
6  
XLogP3:
-3.8  

Literature

Title: Potent inhibition of starch-synthase by Tris-type buffers is responsible for the perpetuation of the primer myth for starch biosynthesis.

Journal: Carbohydrate research 20120701

Title: Clozapine impairs insulin action by up-regulating Akt phosphorylation and Ped/Pea-15 protein abundance.

Journal: Journal of cellular physiology 20120401

Title: The synthesis and biological activity of lipophilic derivatives of bicine conjugated with N³-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP)-an inhibitor of glucosamine-6-phosphate synthase.

Journal: Journal of enzyme inhibition and medicinal chemistry 20120401

Title: Effects of L-arginine on refolding of lysine-tagged human insulin-like growth factor 1 expressed in Escherichia coli.

Journal: Bioprocess and biosystems engineering 20120101

Title: Sur7 promotes plasma membrane organization and is needed for resistance to stressful conditions and to the invasive growth and virulence of Candida albicans.

Journal: mBio 20120101

Title: Crystal structure of a human single domain antibody dimer formed through V(H)-V(H) non-covalent interactions.

Journal: PloS one 20120101

Title: Isolation and characterization of EstC, a new cold-active esterase from Streptomyces coelicolor A3(2).

Journal: PloS one 20120101

Title: FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections.

Journal: mBio 20120101

Title: Methanocella conradii sp. nov., a thermophilic, obligate hydrogenotrophic methanogen, isolated from Chinese rice field soil.

Journal: PloS one 20120101

Title: Assessment of Pseudomonas aeruginosa N5,N10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase as a potential antibacterial drug target.

Journal: PloS one 20120101

Title: Na(+), K(+)-ATPase subunit composition in a human chondrocyte cell line; evidence for the presence of α1, α3, β1, β2 and β3 isoforms.

Journal: International journal of molecular sciences 20120101

Title: Crosstalk between mitochondrial and sarcoplasmic reticulum Ca2+ cycling modulates cardiac pacemaker cell automaticity.

Journal: PloS one 20120101

Title: Sequence-specific binding of recombinant Zbed4 to DNA: insights into Zbed4 participation in gene transcription and its association with other proteins.

Journal: PloS one 20120101

Title: Development and validation of a yeast high-throughput screen for inhibitors of Aβ₄₂ oligomerization.

Journal: Disease models & mechanisms 20111101

Title: An optimal degree of physical and chemical heterogeneity for the origin of life?

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20111027

Title: Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.

Journal: PLoS pathogens 20110901

Title: Identification of neutrophil granule glycoproteins as Lewis(x)-containing ligands cleared by the scavenger receptor C-type lectin.

Journal: The Journal of biological chemistry 20110708

Title: Refined crystal structures of human Ca(2+)/Zn(2+)-binding S100A3 protein characterized by two disulfide bridges.

Journal: Journal of molecular biology 20110506

Title: Lateral diffusion of manganese in the rat brain determined by T(1) relaxation time measured by (1)H MRI.

Journal: The journal of physiological sciences : JPS 20110501

Title: Crystal structure of R120G disease mutant of human αB-crystallin domain dimer shows closure of a groove.

Journal: Journal of molecular biology 20110422

Title: Poly(ADP-ribose)glycohydrolase is an upstream regulator of Ca2+ fluxes in oxidative cell death.

Journal: Cellular and molecular life sciences : CMLS 20110401

Title: Mn-bicine: a low affinity chelate for manganese ion enhanced MRI.

Journal: Magnetic resonance in medicine 20110401

Title: Metabolite cross-feeding enhances virulence in a model polymicrobial infection.

Journal: PLoS pathogens 20110301

Title: Genital tract sequestration of SIV following acute infection.

Journal: PLoS pathogens 20110201

Title: Restoration of photosystem II photochemistry and carbon assimilation and related changes in chlorophyll and protein contents during the rehydration of desiccated Xerophyta scabrida leaves.

Journal: Journal of experimental botany 20110101

Title: Signaling pathways mediating the induction of apple fruitlet abscission.

Journal: Plant physiology 20110101

Title: Rubisco activity in Mediterranean species is regulated by the chloroplastic CO2 concentration under water stress.

Journal: Journal of experimental botany 20110101

Title: A blue native-PAGE analysis of membrane protein complexes in Clostridium thermocellum.

Journal: BMC microbiology 20110101

Title: Biophysical characterization of the olfactomedin domain of myocilin, an extracellular matrix protein implicated in inherited forms of glaucoma.

Journal: PloS one 20110101

Title: Increased expression of interleukin-6 family members and receptors in urinary bladder with cyclophosphamide-induced bladder inflammation in female rats.

Journal: Frontiers in neuroscience 20110101

Title: Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats.

Journal: PloS one 20110101

Title: Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis.

Journal: Molecular neurodegeneration 20110101

Title: Preparation of calibration standards of N1-H paralytic shellfish toxin analogues by large-scale culture of cyanobacterium Anabaena circinalis (TA04).

Journal: Marine drugs 20110101

Title: Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants.

Journal: Reproductive biology and endocrinology : RB&E 20110101

Title: An atypical unfolded protein response in heat shocked cells.

Journal: PloS one 20110101

Title: The acid-tolerant L-arabinose isomerase from the mesophilic Shewanella sp. ANA-3 is highly active at low temperatures.

Journal: Microbial cell factories 20110101

Title: Effects of Kynurenine Pathway Inhibition on NAD Metabolism and Cell Viability in Human Primary Astrocytes and Neurons.

Journal: International journal of tryptophan research : IJTR 20110101

Title: Synthesis of an antiviral drug precursor from chitin using a saprophyte as a whole-cell catalyst.

Journal: Microbial cell factories 20110101

Title: Circulating LH/hCG receptor (LHCGR) may identify pre-treatment IVF patients at risk of OHSS and poor implantation.

Journal: Reproductive biology and endocrinology : RB&E 20110101

Title: Calreticulin controls the rate of assembly of CD1d molecules in the endoplasmic reticulum.

Journal: The Journal of biological chemistry 20101203

Title: Co-chaperones are limiting in a depleted chaperone network.

Journal: Cellular and molecular life sciences : CMLS 20101201

Title: Essential histidine pairs indicate conserved haem binding in epsilonproteobacterial cytochrome c haem lyases.

Journal: Microbiology (Reading, England) 20101201

Title: Discrimination between two possible reaction sequences that create potential risk of generation of deleterious radicals by cytochrome bc₁. Implications for the mechanism of superoxide production.

Journal: Biochimica et biophysica acta 20101101

Title: Bis{2-[bis-(2-hy-droxy-eth-yl)amino]-acetato-κO,N,O'}zinc(II).

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20101001

Title: Combined effects of CO2 and light on the N2-fixing cyanobacterium Trichodesmium IMS101: physiological responses.

Journal: Plant physiology 20100901

Title: Dimerization and DNA-dependent aggregation of the Escherichia coli nucleoid protein and chaperone CbpA.

Journal: Molecular microbiology 20100901

Title: Molecular basis of the waxy endosperm starch phenotype in broomcorn millet (Panicum miliaceum L.).

Journal: Molecular biology and evolution 20100701

Title: Bis[N,N-bis-(2-hy-droxy-eth-yl)glycinato]cobalt(II).

Journal: Acta crystallographica. Section E, Structure reports online 20100701

Title: Comparison of entropic contributions to binding in a 'hydrophilic' versus 'hydrophobic' ligand-protein interaction.

Journal: Journal of the American Chemical Society 20100630

Title: Internal lipid synthesis and vesicle growth as a step toward self-reproduction of the minimal cell.

Journal: Systems and synthetic biology 20100601

Title: Stable adducts of nerve agents sarin, soman and cyclosarin with TRIS, TES and related buffer compounds--characterization by LC-ESI-MS/MS and NMR and implications for analytical chemistry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100515

Title: Trimeric structure of langerin.

Journal: The Journal of biological chemistry 20100423

Title: Nitric oxide mediates the hormonal control of Crassulacean acid metabolism expression in young pineapple plants.

Journal: Plant physiology 20100401

Title: Using structural information to change the phosphotransfer specificity of a two-component chemotaxis signalling complex.

Journal: PLoS biology 20100201

Title: Diacylglycerol-stimulated endocytosis of transferrin in trypanosomatids is dependent on tyrosine kinase activity.

Journal: PloS one 20100101

Title: Automated discovery of novel drug formulations using predictive iterated high throughput experimentation.

Journal: PloS one 20100101

Title: Successful amelioration of mitochondrial optic neuropathy using the yeast NDI1 gene in a rat animal model.

Journal: PloS one 20100101

Title: Characterization of the first beta-class carbonic anhydrase from an arthropod (Drosophila melanogaster) and phylogenetic analysis of beta-class carbonic anhydrases in invertebrates.

Journal: BMC biochemistry 20100101

Title: Induction of early Purkinje cell dendritic differentiation by thyroid hormone requires RORα.

Journal: Neural development 20100101

Title: A role for taurine in mitochondrial function.

Journal: Journal of biomedical science 20100101

Title: Resistance to acidic environments of caries-associated bacteria: Bifidobacterium dentium and Bifidobacterium longum.

Journal: Caries research 20100101

Title: Identification of an archaeal presenilin-like intramembrane protease.

Journal: PloS one 20100101

Title: Synthesis, X-Ray Structure, and Characterization of Catena-bis(benzoate)bis{N,N-bis(2-hydroxyethyl)glycinate}cadmium(II).

Journal: Bioinorganic chemistry and applications 20100101

Title: PEG-based thermogels: applicability in physiological media.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20091216

Title: Targeted glycoproteomic identification of cancer cell glycosylation.

Journal: Glycobiology 20090801

Title: Magnetic interactions sense changes in distance between heme b(L) and the iron-sulfur cluster in cytochrome bc(1).

Journal: Biochemistry 20090623

Title: Coupled growth and division of model protocell membranes.

Journal: Journal of the American Chemical Society 20090422

Title: Structure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation.

Journal: PloS one 20090101

Title: Diabetes changes the levels of ionotropic glutamate receptors in the rat retina.

Journal: Molecular vision 20090101

Title: iQuantitator: a tool for protein expression inference using iTRAQ.

Journal: BMC bioinformatics 20090101

Title: Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons.

Journal: International journal of tryptophan research : IJTR 20090101

Title: Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20081201

Title: Structural insights into mechanism and specificity of O-GlcNAc transferase.

Journal: The EMBO journal 20081022

Title: Loading dependent swelling and release properties of novel biodegradable, elastic and environmental stimuli-sensitive polyurethanes.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20081021

Title: Crucial structural role for the PH and C1 domains of the Vav1 exchange factor.

Journal: EMBO reports 20080701

Title: Structures of the Shigella flexneri type 3 secretion system protein MxiC reveal conformational variability amongst homologues.

Journal: Journal of molecular biology 20080404

Title: A mixture of fortunes: the curious determination of the structure of Escherichia coli BL21 Gab protein.

Journal: Acta crystallographica. Section D, Biological crystallography 20080401

Title: Impact of ligand protonation on higher-order metal complexation kinetics in aqueous systems.

Journal: The journal of physical chemistry. A 20080327

Title: Comparison of time-dependent effects of (+)-methamphetamine or forced swim on monoamines, corticosterone, glucose, creatine, and creatinine in rats.

Journal: BMC neuroscience 20080101

Title: Plant-like substitutions in the large-subunit carboxy terminus of Chlamydomonas Rubisco increase CO2/O2 specificity.

Journal: BMC plant biology 20080101

Title: HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells.

Journal: PloS one 20080101

Title: Focal cerebral ischemia in the TNFalpha-transgenic rat.

Journal: Journal of neuroinflammation 20080101

Title: Herpes simplex virus type 1 Us3 gene deletion influences toll-like receptor responses in cultured monocytic cells.

Journal: Virology journal 20080101

Title: Evaluating performance in three-dimensional fluorescence microscopy.

Journal: Journal of microscopy 20071201

Title: Crystal structure of KPC-2: insights into carbapenemase activity in class A beta-lactamases.

Journal: Biochemistry 20070515

Title: Intravenous immune globulin in hereditary inclusion body myopathy: a pilot study.

Journal: BMC neurology 20070101

Title: Rapid and specific biotin labelling of the erythrocyte surface antigens of both cultured and ex-vivo Plasmodium parasites.

Journal: Malaria journal 20070101

Title: Expression, purification and preliminary crystallographic analysis of oligopeptidase B from Trypanosoma brucei.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20060801

Title: A novel Bicine running buffer system for doubled sodium dodecyl sulfate - polyacrylamide gel electrophoresis of membrane proteins.

Journal: Electrophoresis 20060701

Title: Crystallization and preliminary X-ray diffraction data of the complex between human centrin 2 and a peptide from the protein XPC.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20060701

Title: Linear and branched bicin linkers for releasable PEGylation of macromolecules: controlled release in vivo and in vitro from mono- and multi-PEGylated proteins.

Journal: Bioconjugate chemistry 20060101

Title: Multiplexed expression and screening for recombinant protein production in mammalian cells.

Journal: BMC biotechnology 20060101

Title: Buffers for the physiological pH range: acidic dissociation constants of zwitterionic compounds in various hydroorganic media.

Journal: Annali di chimica 20050101

Title: Identification and partial characterization of the enzyme of omega: one of five putative DPP IV genes in Drosophila melanogaster.

Journal: Journal of insect science (Online) 20050101

Title: Ionic mobilities of duplex and frayed wire DNA in discontinuous buffer electrophoresis: evidence of interactions with amino acids.

Journal: Biochemistry 20041228

Title: Thermodynamic study of the second-stage dissociation of N,N-bis-(2-hydroxyethyl)glycine (bicine) in water at different ionic strength and different solvent mixtures.

Journal: Annali di chimica 20041201

Title: Effects of nitrogen forms on the production of cyanobacterial toxin microcystin-IR by an isolated Microcystis aeruginosa.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20040101

Title: Trypsin activity assay in substrate-specific one- and two-dimensional gels: a powerful method to separate and characterize novel proteases in active form in biological samples.

Journal: Electrophoresis 20030901

Title: Production of two types of exopolysaccharide by Novosphingobium rosa.

Journal: Journal of bioscience and bioengineering 20030101

Title: The effect of pH on the growth of saprotrophic and ectomycorrhizal ammonia fungi in vitro.

Journal: Mycologia 20030101

Title: Determination of the affinity of each component of a composite quaternary transition-state analogue complex of creatine kinase.

Journal: Biochemistry 20020604

Title: The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin.

Journal: Journal of molecular biology 20020510

Title: Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein.

Journal: BMC genomics 20020101

Title: Analysis and enantioresolution of donepezil by capillary electrophoresis.

Journal: Journal of pharmaceutical and biomedical analysis 20010301

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Tags:150-25-4 Molecular Formula|150-25-4 MDL|150-25-4 SMILES|150-25-4 Bicine