Home Amines 15028-41-8
15028-41-8,MFCD00214247
Catalog No.:AA00APFI

15028-41-8 | Alpha-aminoisobutyric acid methyl ester HCl, tech grade

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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00APFI
Chemical Name:
Alpha-aminoisobutyric acid methyl ester HCl, tech grade
CAS Number:
15028-41-8
Molecular Formula:
C5H12ClNO2
Molecular Weight:
153.6073
MDL Number:
MFCD00214247
SMILES:
COC(=O)C(N)(C)C.Cl
Properties
Computed Properties
 
Complexity:
98.6  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  

Literature

Title: Amino acid transport system A is involved in inflammatory nociception in rats.

Journal: Brain research 20120417

Title: System A activity and vascular function in the placental-specific Igf2 knockout mouse.

Journal: Placenta 20111101

Title: Roles of TauT and system A in cytoprotection of rat syncytiotrophoblast cell line exposed to hypertonic stress.

Journal: Placenta 20101101

Title: Functional expression of two system A glutamine transporter isoforms in rat auditory brainstem neurons.

Journal: Neuroscience 20091215

Title: Tertiary active transport of amino acids reconstituted by coexpression of System A and L transporters in Xenopus oocytes.

Journal: American journal of physiology. Endocrinology and metabolism 20090901

Title: System A transporter SAT2 mediates replenishment of dendritic glutamate pools controlling retrograde signaling by glutamate.

Journal: Cerebral cortex (New York, N.Y. : 1991) 20090501

Title: Temperature dependence of rotational disorder in a non-standard amino acid from X-ray crystallography and molecular dynamics simulation.

Journal: Physical chemistry chemical physics : PCCP 20090421

Title: Role of 1alpha,25(OH)2 vitamin D3 on alpha-[1-(14)C]MeAIB accumulation in immature rat testis.

Journal: Steroids 20090201

Title: The SNAT4 isoform of the system A amino acid transporter is functional in human placental microvillous plasma membrane.

Journal: The Journal of physiology 20090101

Title: Glutamine uptake contributes to central sensitization in the medullary dorsal horn.

Journal: Neuroreport 20080716

Title: Acidosis-sensing glutamine pump SNAT2 determines amino acid levels and mammalian target of rapamycin signalling to protein synthesis in L6 muscle cells.

Journal: Journal of the American Society of Nephrology : JASN 20070501

Title: Modulation of epileptiform activity by glutamine and system A transport in a model of post-traumatic epilepsy.

Journal: Neurobiology of disease 20070201

Title: Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet.

Journal: The Journal of physiology 20061101

Title: Human radiation dosimetry of [11C]MeAIB, a new tracer for imaging of system A amino acid transport.

Journal: European journal of nuclear medicine and molecular imaging 20061001

Title: Dynamic regulation of synaptic GABA release by the glutamate-glutamine cycle in hippocampal area CA1.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060816

Title: N,N-dimethyl-beta-alanine as an inexpensive and efficient ligand for palladium-catalyzed Heck reaction.

Journal: Organic letters 20060608

Title: Preparation and tumor affinity testing of the radioiodinated tetrahydroisoquinoline derivative [123I]TIC(OH) for targeting prostate cancer.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20060501

Title: Tyrosine transport in fibroblasts from healthy volunteers and patients with schizophrenia.

Journal: Neuroscience letters 20060130

Title: Impact of forskolin and amino acid depletion upon System A activity and SNAT expression in BeWo cells.

Journal: Biochimie 20060101

Title: IGF regulation of neutral amino acid transport in the BeWo choriocarcinoma cell line (b30 clone): evidence for MAP kinase-dependent and MAP kinase-independent mechanisms.

Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20060101

Title: Functional expression and adaptive regulation of Na+ -dependent neutral amino acid transporter SNAT2/ATA2 in normal human astrocytes under amino acid starved condition.

Journal: Neuroscience letters 20050418

Title: Effect of hyper or hypo-osmotic conditions on neutral amino acid uptake and oxidation in tissues of the crab Chasmagnathus granulata.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050401

Title: Inhibition of system A-mediated glycine transport in cortical synaptosomes by therapeutic concentrations of clozapine: implications for mechanisms of action.

Journal: Molecular psychiatry 20050301

Title: Hormonal regulation of glucose and system A amino acid transport in first trimester placental villous fragments.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050301

Title: System beta and system A amino acid transporters in the feline endotheliochorial placenta.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20041201

Title: N-(methylamino)isobutyric acid inhibits proliferation of CFSC-2C hepatic stellate cells.

Journal: Biochemical pharmacology 20040715

Title: Involvement of K+ channels and calcium-dependent pathways in the action of T3 on amino acid accumulation and membrane potential in Sertoli cells of immature rat testis.

Journal: Life sciences 20040123

Title: Skeletal muscle reprogramming by activation of calcineurin improves insulin action on metabolic pathways.

Journal: The Journal of biological chemistry 20031107

Title: Distribution and pharmacology of alanine-serine-cysteine transporter 1 (asc-1) in rodent brain.

Journal: The European journal of neuroscience 20031001

Title: Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation.

Journal: Journal of neurochemistry 20030401

Title: Leptin stimulates the activity of the system A amino acid transporter in human placental villous fragments.

Journal: The Journal of clinical endocrinology and metabolism 20030301

Title: Uptake of [N-methyl-11C]alpha-methylaminoisobutyric acid in untreated head and neck cancer studied by PET.

Journal: European journal of nuclear medicine and molecular imaging 20030101

Title: Involvement of the system L amino acid transporter on uptake of S-nitroso-L-cysteine, an endogenous S-nitrosothiol, in PC12 cells.

Journal: European journal of pharmacology 20030101

Title: Transport of 14C-gamma-aminobutyric acid into brain, cerebrospinal fluid and choroid plexus in neonatal and adult rats.

Journal: Brain research. Developmental brain research 20021215

Title: The IGF-II-deficient placenta: aspects of its function.

Journal: Trends in endocrinology and metabolism: TEM 20021201

Title: Amino acid uptake in the skeletal muscle measured using [11C]methylaminoisobutyrate (MEAIB) and PET.

Journal: European journal of nuclear medicine and molecular imaging 20021101

Title: Inhibition of system A amino acid transport activity by ethanol in BeWo choriocarcinoma cells.

Journal: American journal of obstetrics and gynecology 20020701

Title: ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline.

Journal: Molecular pharmacology 20020601

Title: ATA2-mediated amino acid uptake following partial hepatectomy is regulated by redistribution to the plasma membrane.

Journal: Archives of biochemistry and biophysics 20020415

Title: Na+-independent transporters, LAT-2 and b0,+, exchange L-DOPA with neutral and basic amino acids in two clonal renal cell lines.

Journal: The Journal of membrane biology 20020315

Title: Physiological importance of system A-mediated amino acid transport to rat fetal development.

Journal: American journal of physiology. Cell physiology 20020101

Title: Glutamine uptake by neurons: interaction of protons with system a transporters.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020101

Title: A chronic low dose infusion of insulin-like growth factor I alters placental function but does not affect fetal growth.

Journal: Reproduction, fertility, and development 20020101

Title: Regulation of glutamate transport and transport proteins in a placental cell line.

Journal: American journal of physiology. Cell physiology 20010901

Title: Effect of 3,5,3'-triiodo-L-thyronine on amino acid accumulation and membrane potential in Sertoli cells of the rat testis.

Journal: Life sciences 20010713

Title: Biodistribution of [11C] methylaminoisobutyric acid, a tracer for PET studies on system A amino acid transport in vivo.

Journal: European journal of nuclear medicine 20010701

Title: Characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport.

Journal: The Journal of biological chemistry 20010629

Title: Osmotic regulation of ATA2 mRNA expression and amino acid transport System A activity.

Journal: Biochemical and biophysical research communications 20010427

Title: Electrogenic Na(+)-dependent L-alanine transport in the lizard duodenum. Involvement of systems A and ASC.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010301

Title: Insulin-like growth factor-I stimulates amino acid transport in a glutamine-deprived human neuroblastoma cell line.

Journal: Biochimica et biophysica acta 20010216

Title: Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A.

Journal: Biochimica et biophysica acta 20010209

Title: Characterization of 3-[(123)I]iodo-L-alpha-methyl tyrosine transport in astrocytes of neonatal rats.

Journal: Journal of neurochemistry 20010101

Title: The effect of heat shock on amino acid transport and cell volume in 3T3 cells.

Journal: Amino acids 20010101

Title: Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A.

Journal: Biochimica et biophysica acta 20000731

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Tags:15028-41-8 Molecular Formula|15028-41-8 MDL|15028-41-8 SMILES|15028-41-8 Alpha-aminoisobutyric acid methyl ester HCl, tech grade