Name: Name:2-Methoxycinnamaldehyde
Brand: AABLOCKS
SKU: AA001MIY
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA001MIY

Chemical Name: 2-Methoxycinnamaldehyde

CAS Number: 1504-74-1

Molecular Formula: C10H10O2

Molecular Weight: 162.1852

MDL Number: MFCD00007001

SMILES: O=CC=Cc1ccccc1OC

FEMA Number: 3181

Properties

Complexity: 163

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 1

Formal Charge: 0

Heavy Atom Count: 12

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 3

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.7

Literature fold

Title: Proton pumping ATPase mediated fungicidal activity of two essential oil components.

Journal: Journal of basic microbiology20121001

Title: Xanthine oxidase inhibitory activity of constituents of Cinnamomum cassia twigs.

Journal: Bioorganic & medicinal chemistry letters20120715

Title: 2-methoxycinnamaldehyde from Cinnamomum cassia reduces rat myocardial ischemia and reperfusion injury in vivo due to HO-1 induction.

Journal: Journal of ethnopharmacology20120131

Title: 2-Methoxycinnamaldehyde inhibits tumor angiogenesis by suppressing Tie2 activation.

Journal: Biochemical and biophysical research communications20111111

Title: Pressurized liquid extraction and GC-MS analysis for simultaneous determination of seven components in Cinnamomum cassia and the effect of sample preparation.

Journal: Journal of separation science20100801

Title: Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation.

Journal: Bioorganic & medicinal chemistry20081015

Title: 2-methoxycinnamaldehyde reduces IL-1beta-induced prostaglandin production in rat cerebral endothelial cells.

Journal: Biological & pharmaceutical bulletin20061101

Title: [Effect of 2-methoxycinnamaldehyde on activity of COX and PGE2 release in cerebral microvascular endothelial cells stimulated by IL-1].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20060701

Title: Potentiation of antifungal activity of amphotericin B by essential oil from Cinnamomum cassia.

Journal: Phytotherapy research : PTR20060101

Title: Cinnamaldehyde and 2-methoxycinnamaldehyde as NF-kappaB inhibitors from Cinnamomum cassia.

Journal: Planta medica20040901

Title: Comparison of adult corn rootworm (Coleoptera: Chrysomelidae) sampling methods.

Journal: Journal of economic entomology20020201

Title: Distribution of MCA-coated grits in maize fields after high wheel tractor application for disrupting orientation of Diabrotica virgifera virgifera LeConte.

Journal: Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen)20020101

Title: Wong HY, et al. Cinnamomum verum Component 2-Methoxycinnamaldehyde: A Novel Anticancer Agent with Both Anti-Topoisomerase I and II Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo. Phytother Res. 2016 Feb;30(2):331-40.

Title: Liu YH, et al. Cinnamomum verum ingredient 2-methoxycinnamaldehyde: a new antiproliferative drug targeting topoisomerase I and II in human lung squamous cell carcinoma NCI-H520 cells. Eur J Cancer Prev. 2017 Jul;26(4):314-323.

Title: Jin YH, et al. 2-Methoxycinnamaldehyde inhibits the TNF-α-induced proliferation and migration of human aortic smooth muscle cells. Int J Mol Med. 2017 Jan;39(1):191-198.

1504-74-1 | 2-Methoxycinnamaldehyde