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150627-37-5,MFCD20488046
Catalog No.:AA00ATB4

150627-37-5 | (R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone

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1mg
≥98%
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$881.00   $617.00
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  • Technical Information
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Technical Information
Catalog Number:
AA00ATB4
Chemical Name:
(R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone
CAS Number:
150627-37-5
Molecular Formula:
C21H36O5
Molecular Weight:
368.5075
MDL Number:
MFCD20488046
SMILES:
CCCCCCCCCCCCCCCC(=O)C1=C(O)[C@H](OC1=O)CO
Properties
Computed Properties
 
Complexity:
455  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
16  
XLogP3:
6.7  

Literature

Title: Prenylflavonoids from Glycyrrhiza uralensis and their protein tyrosine phosphatase-1B inhibitory activities.

Journal: Bioorganic & medicinal chemistry letters 20100915

Title: In vitro reconstruction of tetronate RK-682 biosynthesis.

Journal: Nature chemical biology 20100201

Title: Baculovirus expression system: an alternative for producing catalytically active human PTP-1B.

Journal: Molekuliarnaia biologiia 20100101

Title: Cytotoxic and PTP1B inhibitory activities from Erythrina abyssinica.

Journal: Bioorganic & medicinal chemistry letters 20091201

Title: Protein tyrosine phosphatase 1B inhibitors isolated from Morus bombycis.

Journal: Bioorganic & medicinal chemistry letters 20091201

Title: Flavanones from the stem bark of Erythrina abyssinica.

Journal: Bioorganic & medicinal chemistry 20081215

Title: Triterpenoids from the leaves of Diospyros kaki (persimmon) and their inhibitory effects on protein tyrosine phosphatase 1B.

Journal: Journal of natural products 20081001

Title: Usimines A-C, bioactive usnic acid derivatives from the Antarctic lichen Stereocaulon alpinum.

Journal: Journal of natural products 20080401

Title: Ohioensins F and G: protein tyrosine phosphatase 1B inhibitory benzonaphthoxanthenones from the Antarctic moss Polytrichastrum alpinum.

Journal: Bioorganic & medicinal chemistry letters 20080115

Title: Design, synthesis, and discovery of stilbene derivatives based on lithospermic acid B as potent protein tyrosine phosphatase 1B inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20070815

Title: Isoprenylated flavonoids from the stem bark of Erythrina abyssinica.

Journal: Journal of natural products 20070601

Title: Protein tyrosine phosphatase-1B inhibitory activity of isoprenylated flavonoids isolated from Erythrina mildbraedii.

Journal: Journal of natural products 20061101

Title: Protein tyrosine phosphatase 1B inhibitory activity of triterpenes isolated from Astilbe koreana.

Journal: Bioorganic & medicinal chemistry letters 20060615

Title: Inhibition of protein tyrosine phosphatase 1B by diterpenoids isolated from Acanthopanax koreanum.

Journal: Bioorganic & medicinal chemistry letters 20060601

Title: Protein tyrosine phosphatase 1B inhibitors from Morus root bark.

Journal: Bioorganic & medicinal chemistry letters 20060301

Title: Solution-phase and solid-phase syntheses of enzyme inhibitor RK-682 and antibiotic agglomerins.

Journal: The Journal of organic chemistry 20050722

Title: Structure-based design of a selective heparanase inhibitor as an antimetastatic agent.

Journal: Molecular cancer therapeutics 20040901

Title: Exploitation of heparanase inhibitors from microbial metabolites using an efficient visual screening system.

Journal: The Journal of antibiotics 20040201

Title: Conversion of Ca2+ salt of an organic compound to its Li+ salt to simplify the fast atom bombardment mass spectrum.

Journal: Chemical & pharmaceutical bulletin 20031101

Title: Design and synthesis of a dimeric derivative of RK-682 with increased inhibitory activity against VHR, a dual-specificity ERK phosphatase: implications for the molecular mechanism of the inhibition.

Journal: Chemistry & biology 20011201

Title: Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition.

Journal: Journal of medicinal chemistry 20010927

Title: Asymmetric synthesis of a 3-acyltetronic acid derivative, RK-682, and formation of its calcium salt during silica gel column chromatography.

Journal: Chemical & pharmaceutical bulletin 20010201

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Tags:150627-37-5 Molecular Formula|150627-37-5 MDL|150627-37-5 SMILES|150627-37-5 (R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone