Home Other Building Blocks 151060-21-8
151060-21-8,MFCD00864925
Catalog No.:AA001MYX

151060-21-8 | Balofloxacin dihydrate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$79.00   $55.00
- +
5g
98%
in stock  
$211.00   $148.00
- +
10g
98%
in stock  
$361.00   $253.00
- +
25g
98%
in stock  
$710.00   $497.00
- +
100g
98%
in stock  
$1,640.00   $1,148.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001MYX
Chemical Name:
Balofloxacin dihydrate
CAS Number:
151060-21-8
Molecular Formula:
C20H28FN3O6
Molecular Weight:
425.4512
MDL Number:
MFCD00864925
SMILES:
CNC1CCCN(C1)c1c(F)cc2c(c1OC)n(cc(c2=O)C(=O)O)C1CC1.O.O
Properties
Computed Properties
 
Complexity:
668  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
1  

Downstream Synthesis Route

[1]CurrentPatentAssignee:HUAITINFREEPHARMACEUTICALCOLTD-CN114213392,2022,A

[1]CurrentPatentAssignee:HUAITINFREEPHARMACEUTICALCOLTD-CN114213392,2022,ALocationinpatent:Paragraph0035;0045-0046;0058;0062-0063;0067

Literature

Title: Alterations of protein complexes and pathways in genetic information flow and response to stimulus contribute to Escherichia coli resistance to balofloxacin.

Journal: Molecular bioSystems 20120901

Title: Downregulation of Na(+)-NQR complex is essential for Vibrio alginolyticus in resistance to balofloxacin.

Journal: Journal of proteomics 20120517

Title: Synthesis and in vitro antimycobacterial activity of balofloxacin ethylene isatin derivatives.

Journal: European journal of medicinal chemistry 20100801

Title: Gatifloxacin, moxifloxacin, and balofloxacin resistance due to mutations in the gyrA and parC genes of Staphylococcus epidermidis strains isolated from patients with endophthalmitis, corneal ulcers and conjunctivitis.

Journal: Ophthalmic research 20090101

Title: [Determination of balofloxacin in human plasma by HPLC with solid-phase extraction].

Journal: Se pu = Chinese journal of chromatography 20071101

Title: High performance liquid chromatography-electrospray ionization mass spectrometric determination of balofloxacin in human plasma and its pharmacokinetics.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

Title: [Studies on the reaction of balofloxacin with bovine serum albumin].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20060801

Title: Electrophysiological safety of novel fluoroquinolone antibiotic agents gemifloxacin and balofloxacin.

Journal: Drug and chemical toxicology 20060101

Title: [Interaction between balofloxacin and DNA and the influence of Mg2+ on the interaction].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050701

Title: Balofloxacin Choongwae.

Journal: Current opinion in investigational drugs (London, England : 2000) 20030201

Title: [In vitro antimycobacterial activities of a new quinolone, balofloxacin].

Journal: Kekkaku : [Tuberculosis] 20010101

Title: [Determination of antimycobacterial activities of fluoroquinolones against clinical isolates of Mycobacterium tuberculosis: comparative determination with egg-based Ogawa and agar-based Middlebrook 7H10 media].

Journal: Kekkaku : [Tuberculosis] 19960801

Title: Alksne L. Balofloxacin Choongwae. Curr Opin Investig Drugs. 2003 Feb;4(2):224-9.

Title: Jiang H, et, al. In vitro and in vivo effectiveness evaluation of balofloxacin in experimental Staphylococcus aureus keratitis. J Ocul Pharmacol Ther. 2014 Aug;30(6):482-8.

Title: Gohara Y, et, al. In vitro and in vivo activities of Q-35, a new fluoroquinolone, against Mycoplasma pneumonia. Antimicrob Agents Chemother. 1993 Sep;37(9):1826-30.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:151060-21-8 Molecular Formula|151060-21-8 MDL|151060-21-8 SMILES|151060-21-8 Balofloxacin dihydrate