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151606-29-0,MFCD00797629
Catalog No.:AA001NDF

151606-29-0 | Acetic acid, 2-[[2-methyl-8-[[(4-methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]-

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1mg
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$374.00   $262.00
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5mg
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$588.00   $412.00
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25mg
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$1,936.00   $1,355.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001NDF
Chemical Name:
Acetic acid, 2-[[2-methyl-8-[[(4-methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]-
CAS Number:
151606-29-0
Molecular Formula:
C19H18N2O5S
Molecular Weight:
386.4216
MDL Number:
MFCD00797629
SMILES:
OC(=O)COc1cc(NS(=O)(=O)c2ccc(cc2)C)c2c(c1)ccc(n2)C
Properties
Computed Properties
 
Complexity:
612  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
3  

Literature

Title: Sensor specific imaging of proteomic Zn2+ with zinquin and TSQ after cellular exposure to N-ethylmaleimide.

Journal: Metallomics : integrated biometal science 20120502

Title: Apical localization of zinc transporter ZnT4 in human airway epithelial cells and its loss in a murine model of allergic airway inflammation.

Journal: Nutrients 20111101

Title: Reactions of the fluorescent sensor, Zinquin, with the zinc-proteome: adduct formation and ligand substitution.

Journal: Inorganic chemistry 20111017

Title: Decreased zinc and downregulation of ZIP3 zinc uptake transporter in the development of pancreatic adenocarcinoma.

Journal: Cancer biology & therapy 20110815

Title: Sputum zinc concentration and clinical outcome in older asthmatics.

Journal: Respirology (Carlton, Vic.) 20110401

Title: Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation.

Journal: The EMBO journal 20110202

Title: Zinc signals promote IL-2-dependent proliferation of T cells.

Journal: European journal of immunology 20100501

Title: Polyphenol-rich beverages enhance zinc uptake and metallothionein expression in Caco-2 cells.

Journal: Journal of food science 20100501

Title: 3,3'-Dihydroxyisorenieratene prevents UV-induced formation of reactive oxygen species and the release of protein-bound zinc ions in human skin fibroblasts.

Journal: Molecular nutrition & food research 20100201

Title: Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion.

Journal: PloS one 20090101

Title: Expression of ZnT and ZIP zinc transporters in the human RPE and their regulation by neurotrophic factors.

Journal: Investigative ophthalmology & visual science 20080301

Title: Trichomes of tobacco excrete zinc as zinc-substituted calcium carbonate and other zinc-containing compounds.

Journal: Plant physiology 20060701

Title: Zinquin identifies subcellular compartmentalization of zinc in cortical neurons. Relation to the trafficking of zinc and the mitochondrial compartment.

Journal: Brain research 20060426

Title: Apoptosis may underlie the pathology of zinc-deficient skin.

Journal: Immunology and cell biology 20060201

Title: Neuronal zinc stores are modulated by non-steroidal anti-inflammatory drugs: an optical analysis in cultured hippocampal neurons.

Journal: Brain research 20051102

Title: S100A9 deficiency alters adenosine-5'-triphosphate induced calcium signalling but does not generally interfere with calcium and zinc homeostasis in murine neutrophils.

Journal: The international journal of biochemistry & cell biology 20050601

Title: Perinatal omega-3 polyunsaturated fatty acid supply modifies brain zinc homeostasis during adulthood.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20050517

Title: The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the Golgi apparatus.

Journal: The Journal of biological chemistry 20050415

Title: Zinc has ambiguous effects on chromium (VI)-induced oxidative stress and apoptosis.

Journal: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20050101

Title: Fluctuations of cellular, available zinc modulate insulin signaling via inhibition of protein tyrosine phosphatases.

Journal: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20050101

Title: Exchangeable zinc ions transiently accumulate in a vesicular compartment in the yeast Saccharomyces cerevisiae.

Journal: Biochemical and biophysical research communications 20041008

Title: S-Nitroso compounds interfere with zinc probing by Zinquin.

Journal: Analytical biochemistry 20040901

Title: Monitoring apoptosis with fluorescent Zn2+-indicators.

Journal: Science's STKE : signal transduction knowledge environment 20040302

Title: Apoptosis in the normal and inflamed airway epithelium: role of zinc in epithelial protection and procaspase-3 regulation.

Journal: Biochemical pharmacology 20031015

Title: Coordination and fluorescence of the intracellular Zn2+ probe [2-methyl-8-(4-toluenesulfonamido)-6-quinolyloxy]acetic acid (Zinquin A) in ternary Zn2+ complexes.

Journal: Journal of the American Chemical Society 20030402

Title: Intracellular zinc fluxes associated with apoptosis in growth plate chondrocytes.

Journal: Journal of cellular biochemistry 20030401

Title: Intracellular distribution of labile Zn(II) and zinc transporter expression in kidney and MDCK cells.

Journal: American journal of physiology. Renal physiology 20021201

Title: Intracellular zinc distribution and transport in C6 rat glioma cells.

Journal: Biochemical and biophysical research communications 20020830

Title: DNA damage-induced [Zn(2+)](i) transients: correlation with cell cycle arrest and apoptosis in lymphoma cells.

Journal: American journal of physiology. Cell physiology 20020801

Title: Constitutive expression of hZnT4 zinc transporter in human breast epithelial cells.

Journal: The Biochemical journal 20020515

Title: pH dependence and compartmentalization of zinc transported across plasma membrane of rat cortical neurons.

Journal: American journal of physiology. Cell physiology 20020201

Title: Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thionein.

Journal: American journal of physiology. Lung cellular and molecular physiology 20020201

Title: Localization of zinc after in vitro mineralization in osteoblastic cells.

Journal: Biological trace element research 20011001

Title: Spatial organization of Ca(2+) entry and exocytosis in mouse pancreatic beta-cells.

Journal: Biochemical and biophysical research communications 20010817

Title: A decrease in intracellular zinc level precedes the detection of early indicators of apoptosis in HL-60 cells.

Journal: Apoptosis : an international journal on programmed cell death 20010601

Title: Fluorescent detection of Zn(2+)-rich vesicles with Zinquin: mechanism of action in lipid environments.

Journal: Biophysical journal 20010301

Title: Zinc inhibits interleukin-1-dependent T cell stimulation.

Journal: European journal of immunology 19971001

Title: Nowakowski A, et al. Sensor specific imaging of proteomic Zn2+ with zinquin and TSQ after cellular exposure to N-ethylmaleimide. Metallomics. 2012 May;4(5):448-56.

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Tags:151606-29-0 Molecular Formula|151606-29-0 MDL|151606-29-0 SMILES|151606-29-0 Acetic acid, 2-[[2-methyl-8-[[(4-methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]-