Catalog No.:AA003418

152460-10-1 | N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

Name: Name:N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
Brand: AABLOCKS
SKU: AA003418
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Technical Information
Properties
Upstream Synthesis Route
Downstream Synthesis Route
Literature
Request for Quotation
Download SDS

Technical Information
Properties
Upstream Synthesis Route
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA003418

Chemical Name:

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

CAS Number:

152460-10-1

Molecular Formula:

C16H15N5

Molecular Weight:

277.3238

MDL Number:

MFCD09028125

SMILES:

Nc1ccc(c(c1)Nc1nccc(n1)c1cccnc1)C

Properties

BP:

537.3°C at 760 mmHg

Form:

Solid

MP:

133-135 °C

Storage:

Inert atmosphere;2-8℃;

Computed Properties

Complexity:

324

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

2.4

Upstream Synthesis Route

876-08-4

152460-10-1

404844-11-7

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[5]Patent:US9095622,2015,B2,.Locationinpatent:Page/Pagecolumn33

[6]OrganicLetters,2012,vol.14,#15,p.3920-3923

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[10]Zh.Org.Khim.,2015,vol.51,#1,p.104-111,8

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[15]AngewandteChemie,2015,vol.127,#1,p.181-185,5

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1642-81-5

152460-10-1

404844-11-7

[1]Patent:WO2011/95835,2011,A1,.Locationinpatent:Page/Pagecolumn32

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Downstream Synthesis Route

152460-09-8

152460-10-1

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98-88-4

152460-10-1

152459-94-4

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874-60-2

152460-10-1

4-methyl-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide

[1]Yao,Ri-Sheng;Guan,Qiu-Xiang;Lu,Xiao-Qin;Ruan,Ban-Feng[Lettersindrugdesignanddiscovery,2015,vol.12,#1,p.20-28]

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152460-10-1

148077-69-4

152459-95-5

[1]CurrentPatentAssignee:WAVELENGTHPHARMACEUTICALSLTD-US2006/149061,2006,A1Locationinpatent:Page/Pagecolumn9

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876-08-4

152460-10-1

404844-11-7

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[2]Patent:WO2014/204856,2014,A1.Locationinpatent:Paragraph0310-0311

[3]Patent:WO2006/71130,2006,A2.Locationinpatent:Page/Pagecolumn25-27

[4]TetrahedronLetters,2012,vol.53,p.6657-6661

[5]Patent:US9095622,2015,B2.Locationinpatent:Page/Pagecolumn33

[6]OrganicLetters,2012,vol.14,p.3920-3923

[7]OrganicProcessResearchandDevelopment,2008,vol.12,p.490-495

[8]Patent:CN104844566,2018,B.Locationinpatent:Paragraph0124-0126

[9]RussianJournalofOrganicChemistry,2015,vol.51,p.101-109 Zh.Org.Khim.,2015,vol.51,p.104-111,8

[10]EuropeanJournalofMedicinalChemistry,2018,vol.150,p.366-384

[11]Patent:EP3133069,2017,A1.Locationinpatent:Paragraph0039

[12]Patent:WO2004/108699,2004,A1.Locationinpatent:Page20-43

[13]AngewandteChemie-InternationalEdition,2015,vol.54,p.179-183 Angew.Chem.,2015,vol.127,p.181-185,5 AngewandteChemie,2015,vol.127,p.181-185,5

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Literature

Title: Nonaqueous capillary electrophoresis of imatinib mesylate and related substances.

Journal: Journal of separation science 20120801

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