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153088-73-4,MFCD00674885
Catalog No.:AA00AOQ5

153088-73-4 | Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE

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5mg
≥98%
in stock  
$95.00   $66.00
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10mg
≥98%
in stock  
$140.00   $98.00
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25mg
≥98%
in stock  
$326.00   $228.00
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50mg
≥98%
in stock  
$602.00   $421.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00AOQ5
Chemical Name:
Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE
CAS Number:
153088-73-4
Molecular Formula:
C20H17Cl2NO7
Molecular Weight:
454.2575
MDL Number:
MFCD00674885
SMILES:
OC(=O)CC(C(=O)COC(=O)c1c(Cl)cccc1Cl)NC(=O)OCc1ccccc1
Properties
Properties
 
Form:
Solid  

Computed Properties
 
Complexity:
614  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
11  
XLogP3:
3.6  

Literature

Title: [Role of NF-kappaB pathway in shikonin induced apoptosis in oral squamous cell carcinoma Tca-8113 cells].

Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology 20100201

Title: Calpain- and caspase-mediated alphaII-spectrin and tau proteolysis in rat cerebrocortical neuronal cultures after ecstasy or methamphetamine exposure.

Journal: The international journal of neuropsychopharmacology 20070801

Title: Incadronate induces cell detachment and apoptosis in prostatic PC-3 cells.

Journal: Anticancer research 20070101

Title: Rescue system for measles virus from cloned cDNA driven by vaccinia virus Lister vaccine strain.

Journal: Journal of virological methods 20061001

Title: Apoptosis, necrosis and cell proliferation-inhibition by cyclosporine A in U937 cells (a human monocytic cell line).

Journal: Pharmacological research 20060301

Title: Glycyrrhizin induces apoptosis in human stomach cancer KATO III and human promyelotic leukemia HL-60 cells.

Journal: International journal of molecular medicine 20050801

Title: Effects of organ preservation, ischemia time and caspase inhibition on apoptosis and microcirculation in rat pancreas transplantation.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040701

Title: Caspase inhibitors attenuate superantigen-induced inflammatory cytokines, chemokines, and T-cell proliferation.

Journal: Clinical and diagnostic laboratory immunology 20040501

Title: Mechanism of mahanine-induced apoptosis in human leukemia cells (HL-60).

Journal: Biochemical pharmacology 20040101

Title: Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade.

Journal: American journal of respiratory cell and molecular biology 20030701

Title: High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501

Title: Hematopoietic stem cells from the marrow of mice treated with Flt3 ligand are significantly expanded but exhibit reduced engraftment potential.

Journal: Transplantation 20020427

Title: Amelioration of myocardial global ischemia/reperfusion injury with volume-regulatory chloride channel inhibitors in vivo.

Journal: Transplantation 20020427

Title: A cellular mechanism that reversibly inactivates pancaspase inhibitor zAsp-CH(2)-DCB: a potential pitfall causing discrepancy between in vitro and in vivo caspase assays.

Journal: Biochemical and biophysical research communications 20020308

Title: A critical role for ethylene in hydrogen peroxide release during programmed cell death in tomato suspension cells.

Journal: Planta 20020201

Title: Caspase-mediated calcineurin activation contributes to IL-2 release during T cell activation.

Journal: Biochemical and biophysical research communications 20010803

Title: TNF-alpha stimulates caspase-3 activation and apoptotic cell death in primary septo-hippocampal cultures.

Journal: Journal of neuroscience research 20010415

Title: Calcium/calmodulin-dependent protein kinase inhibition potentiates thapsigargin-mediated cell death in SH-SY5Y human neuroblastoma cells.

Journal: Neuroscience letters 20010330

Title: Bovine herpesvirus 1 glycoprotein G is required for prevention of apoptosis and efficient viral growth in rabbit kidney cells.

Journal: Virology 20010120

Title: Caspase-3-like activity is necessary for IL-2 release in activated Jurkat T-cells.

Journal: Experimental cell research 19981010

Title: The Ah receptor is not involved in 2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated apoptosis in human leukemic T cell lines.

Journal: The Journal of biological chemistry 19980731

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Tags:153088-73-4 Molecular Formula|153088-73-4 MDL|153088-73-4 SMILES|153088-73-4 Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE