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Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
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Title: Mechanisms of action of hormone-sensitive lipase in mouse Leydig cells: its role in the regulation of the steroidogenic acute regulatory protein.
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Title: Regulation of sphingomyelin phosphodiesterase acid-like 3A gene (SMPDL3A) by liver X receptors.
Journal: Molecular pharmacology 20121001
Title: The combination of tamoxifen and the rexinoid LG100268 prevents ER-positive and ER-negative mammary tumors in p53-null mammary gland mice.
Journal: Cancer prevention research (Philadelphia, Pa.) 20121001
Title: Tributyltin synergizes with 20-hydroxyecdysone to produce endocrine toxicity.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110901
Title: Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.
Journal: Molecular endocrinology (Baltimore, Md.) 20101101
Title: Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer.
Journal: Cancer prevention research (Philadelphia, Pa.) 20101101
Title: Retinoic acid regulates myelin formation in the peripheral nervous system.
Journal: Glia 20100901
Title: Gene regulation of CYP4F11 in human keratinocyte HaCaT cells.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100101
Title: Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice.
Journal: Cancer prevention research (Philadelphia, Pa.) 20091201
Title: Placental steroidogenesis in rats is independent of signaling pathways induced by retinoic acids.
Journal: General and comparative endocrinology 20090915
Title: Peroxisome proliferator-activated receptor-gamma and retinoid X receptor agonists synergistically suppress proliferation of immortalized endometrial stromal cells.
Journal: Fertility and sterility 20090501
Title: Rexinoids modulate steroid and xenobiotic receptor activity by increasing its protein turnover in a calpain-dependent manner.
Journal: The Journal of biological chemistry 20080808
Title: Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080715
Title: The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis.
Journal: Molecular cancer therapeutics 20080501
Title: Development and quality of bovine morulae cultured in serum-free medium with specific retinoid receptor agonists.
Journal: Reproduction, fertility, and development 20080101
Title: PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.
Journal: Cancer biology & therapy 20071201
Title: Retinoid receptor-specific agonists regulate bovine in vitro early embryonic development, differentiation and expression of genes related to cell cycle arrest and apoptosis.
Journal: Theriogenology 20071101
Title: In silico prediction of pregnane X receptor activators by machine learning approaches.
Journal: Molecular pharmacology 20070101
Title: Identification of biomarkers modulated by the rexinoid LGD1069 (bexarotene) in human breast cells using oligonucleotide arrays.
Journal: Cancer research 20061215
Title: The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061001
Title: Neu-induced retroviral rat mammary carcinogenesis: a novel chemoprevention model for both hormonally responsive and nonresponsive mammary carcinomas.
Journal: Cancer research 20060701
Title: PPARalpha activators and fasting induce the expression of adipose differentiation-related protein in liver.
Journal: Journal of lipid research 20060501
Title: Organotin compounds enhance 17beta-hydroxysteroid dehydrogenase type I activity in human choriocarcinoma JAr cells: potential promotion of 17beta-estradiol biosynthesis in human placenta.
Journal: Biochemical pharmacology 20060428
Title: Receptor-selective retinoids inhibit the growth of normal and malignant breast cells by inducing G1 cell cycle blockade.
Journal: Breast cancer research and treatment 20060301
Title: Coactivation of liver receptor homologue-1 by peroxisome proliferator-activated receptor gamma coactivator-1alpha on aromatase promoter II and its inhibition by activated retinoid X receptor suggest a novel target for breast-specific antiestrogen therapy.
Journal: Cancer research 20051215
Title: Distinct mechanisms of glucose lowering by specific agonists for peroxisomal proliferator activated receptor gamma and retinoic acid X receptors.
Journal: The Journal of biological chemistry 20051118
Title: Trialkyltin compounds bind retinoid X receptor to alter human placental endocrine functions.
Journal: Molecular endocrinology (Baltimore, Md.) 20051001
Title: Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells.
Journal: Endocrinology 20050801
Title: Thiazolidinediones inhibit proliferation of microvascular and macrovascular cells by a PPARgamma-independent mechanism.
Journal: Diabetologia 20050301
Title: Activation of peroxisome proliferator-activated receptor-gamma and retinoid X receptor inhibits aromatase transcription via nuclear factor-kappaB.
Journal: Endocrinology 20050101
Title: Rexinoids may be ready for prime time in prevention, but challenges remain.
Journal: Journal of the National Cancer Institute 20041215
Title: Molecular cloning and characterization of two novel human RXR alpha splice variants.
Journal: The Journal of steroid biochemistry and molecular biology 20040901
Title: Spatiotemporal retinoid-X receptor activation detected in live vertebrate embryos.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20040615
Title: The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor beta-dependent apoptosis in breast cancer.
Journal: Cancer research 20040515
Title: Design, synthesis and structure-activity relationship of novel RXR-selective modulators.
Journal: Bioorganic & medicinal chemistry letters 20040322
Title: Design and synthesis of novel RXR-selective modulators with improved pharmacological profile.
Journal: Bioorganic & medicinal chemistry letters 20031117
Title: Design, synthesis, and structure-activity relationship studies of novel 6,7-locked-[7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta]-2,4,6-trienoic acids.
Journal: Journal of medicinal chemistry 20030911
Title: Novel (2E,4E,6Z)-7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic acid retinoid X receptor modulators are active in models of type 2 diabetes.
Journal: Journal of medicinal chemistry 20030619
Title: Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding.
Journal: The Journal of biological chemistry 20030321
Title: Prevention and treatment of experimental breast cancer with the combination of a new selective estrogen receptor modulator, arzoxifene, and a new rexinoid, LG 100268.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20021001
Title: Mechanism of selective retinoid X receptor agonist-induced hypothyroidism in the rat.
Journal: Endocrinology 20020801
Title: Redundant pathways for negative feedback regulation of bile acid production.
Journal: Developmental cell 20020601
Title: The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12.
Journal: The Journal of biological chemistry 20020329
Title: Regional differences in the response of human pre-adipocytes to PPARgamma and RXRalpha agonists.
Journal: Diabetes 20020301
Title: PPARgamma is not a critical mediator of primary monocyte differentiation or foam cell formation.
Journal: Biochemical and biophysical research communications 20020118
Title: Regulation of aromatase by nuclear receptors.
Journal: The Journal of steroid biochemistry and molecular biology 20011201
Title: Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
Journal: The Journal of clinical investigation 20011001
Title: The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo.
Journal: Molecular endocrinology (Baltimore, Md.) 20010801
Title: Combined treatment with specific ligands for PPARgamma:RXR nuclear receptor system markedly inhibits the expression of cytochrome P450arom in human granulosa cancer cells.
Journal: Molecular and cellular endocrinology 20010705
Title: Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents.
Journal: Molecular pharmacology 20010401
Title: Peroxisome proliferator-activated receptor (PPAR) gamma and retinoid X receptor (RXR) agonists have complementary effects on glucose and lipid metabolism in human skeletal muscle.
Journal: Diabetologia 20010401
Title: Metabolic effects of rexinoids: tissue-specific regulation of lipoprotein lipase activity.
Journal: Molecular pharmacology 20010201
Title: Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).
Journal: Gene 20010110
Title: The effects of rexinoids and rosiglitazone on body weight and uncoupling protein isoform expression in the Zucker fa/fa rat.
Journal: Metabolism: clinical and experimental 20001201
Title: A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma.
Journal: Molecular endocrinology (Baltimore, Md.) 20001001
Title: Insulin sensitizer, troglitazone, directly inhibits aromatase activity in human ovarian granulosa cells.
Journal: Biochemical and biophysical research communications 20000519
Title: Induction of the fatty acid transport protein 1 and acyl-CoA synthase genes by dimer-selective rexinoids suggests that the peroxisome proliferator-activated receptor-retinoid X receptor heterodimer is their molecular target.
Journal: The Journal of biological chemistry 20000428
Title: The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.
Journal: Molecular endocrinology (Baltimore, Md.) 20000101
Title: Therapeutic applications for ligands of retinoid receptors.
Journal: Current pharmaceutical design 20000101
Title: Growth inhibition of myeloid leukemia cells by troglitazone, a ligand for peroxisome proliferator activated receptor gamma, and retinoids.
Journal: International journal of oncology 19991101
Title: Activation of specific RXR heterodimers by an antagonist of RXR homodimers.
Journal: Nature 19961003
Title: Retinoids increase human apolipoprotein A-11 expression through activation of the retinoid X receptor but not the retinoic acid receptor.
Journal: Molecular and cellular biology 19960701
Title: Synthesis of high specific activity [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties.
Journal: Journal of medicinal chemistry 19940204
