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154-02-9,MFCD00047197
Catalog No.:AA00APDH

154-02-9 | 5-Hydroxytryptophol

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5mg
≥98%
in stock  
$46.00   $32.00
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10mg
≥98%
in stock  
$79.00   $55.00
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250mg
in stock  
$137.00   $96.00
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1g
in stock  
$345.00   $242.00
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5g
95%
in stock  
$1,258.00   $881.00
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10g
95%
in stock  
$2,007.00   $1,405.00
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25g
95%
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$4,002.00   $2,802.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00APDH
Chemical Name:
5-Hydroxytryptophol
CAS Number:
154-02-9
Molecular Formula:
C10H11NO2
Molecular Weight:
177.1998
MDL Number:
MFCD00047197
SMILES:
OCCc1c[nH]c2c1cc(O)cc2
NSC Number:
84416
Properties
Properties
 
Form:
Solid  
MP:
111-113°C  
Storage:
-20 ℃;Light sensitive;Inert atmosphere;  

Computed Properties
 
Complexity:
174  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
0.5  

Literature

Title: [The laboratory diagnostics of alcoholic disease].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20120401

Title: [Biomarkers of alcohol abuse. Part II. New biomarkers and their interpretation].

Journal: Psychiatria polska 20100101

Title: Circulating Antibodies to IDO/THO Pathway Metabolites in Alzheimer's Disease.

Journal: International journal of Alzheimer's disease 20100101

Title: New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists.

Journal: Neuropsychiatric disease and treatment 20090101

Title: [Diagnosis of alcohol abuse].

Journal: Przeglad lekarski 20090101

Title: Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model.

Journal: International journal of tryptophan research : IJTR 20090101

Title: Selective serotonin reuptake inhibitors: a review of its effects on intraocular pressure.

Journal: Current neuropharmacology 20081201

Title: Objective post-mortem diagnosis of chronic alcohol abuse--a review of studies on new markers.

Journal: Legal medicine (Tokyo, Japan) 20080901

Title: Acyclovir inhibits rat liver tryptophan-2,3-dioxygenase and induces a concomitant rise in brain serotonin and 5-hydroxyindole acetic acid levels.

Journal: Metabolic brain disease 20080901

Title: HPLC determination of serotonin and its metabolites from human platelet-rich plasma; shift to 5-hydroxytryptophol formation following alcohol consumption.

Journal: Journal of chromatographic science 20080201

Title: Biomarkers of alcoholism: an updated review.

Journal: Scandinavian journal of clinical and laboratory investigation 20080101

Title: Comparison between the urinary alcohol markers EtG, EtS, and GTOL/5-HIAA in a controlled drinking experiment.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20080101

Title: Loss of ethanol from vitreous humor in drowning death.

Journal: Journal of analytical toxicology 20071001

Title: Alcohol biomarker analysis: simultaneous determination of 5-hydroxytryptophol glucuronide and 5-hydroxyindoleacetic acid by direct injection of urine using ultra-performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20070701

Title: Biomarkers in alcoholism.

Journal: Clinica chimica acta; international journal of clinical chemistry 20070201

Title: Determination of glucuronidated 5-hydroxytryptophol (GTOL), a marker of recent alcohol intake, by ELISA technique.

Journal: Clinical biochemistry 20070101

Title: Problem drinking in relation to treatment outcome among opiate addicts in methadone maintenance treatment.

Journal: Drug and alcohol review 20070101

Title: Biomarkers to disclose recent intake of alcohol: potential of 5-hydroxytryptophol glucuronide testing using new direct UPLC-tandem MS and ELISA methods.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20070101

Title: UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: II. Functional impact of the three most common nonsynonymous UGT1A6 polymorphisms (S7A, T181A, and R184S).

Journal: The Journal of pharmacology and experimental therapeutics 20050601

Title: Detection of recent ethanol intake with new markers: comparison of fatty acid ethyl esters in serum and of ethyl glucuronide and the ratio of 5-hydroxytryptophol to 5-hydroxyindole acetic acid in urine.

Journal: Alcoholism, clinical and experimental research 20050501

Title: Utilizing the urinary 5-HTOL/5-HIAA ratio to determine ethanol origin in civil aviation accident victims.

Journal: Journal of forensic sciences 20050501

Title: One electron oxidation induced dimerization of 5-hydroxytryptophol: role of 5-hydroxy substitution.

Journal: The journal of physical chemistry. A 20050317

Title: Determination of urinary 5-hydroxytryptophol glucuronide by liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

Title: Comparison of serum fatty acid ethyl esters and urinary 5-hydroxytryptophol as biochemical markers of recent ethanol consumption.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20050101

Title: Prevalence of high alcohol and benzodiazepine consumption in sleep apnea patients studied with blood and urine tests.

Journal: Acta oto-laryngologica 20041201

Title: Evaluation of 5-hydroxytryptophol and other endogenous serotonin (5-hydroxytryptamine) analogs as substrates for UDP-glucuronosyltransferase 1A6.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040801

Title: Accurate assignment of ethanol origin in postmortem urine: liquid chromatographic-mass spectrometric determination of serotonin metabolites.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040615

Title: Reserpine methonitrate, a novel quaternary analogue of reserpine augments urinary excretion of VMA and 5-HIAA without affecting HVA in rats.

Journal: BMC pharmacology 20040101

Title: Effects of acute and short-term administration of tryptophan plus ethanol on noradrenaline and serotonin metabolites in the locus coeruleus.

Journal: Alcohol (Fayetteville, N.Y.) 20040101

Title: Expression of human organic anion transporters in the choroid plexus and their interactions with neurotransmitter metabolites.

Journal: Journal of pharmacological sciences 20031201

Title: 5-hydroxytryptophol as a marker for recent alcohol intake.

Journal: Addiction (Abingdon, England) 20031201

Title: Characterization of the serotoninergic system in the C57BL/6 mouse skin.

Journal: European journal of biochemistry 20030801

Title: Biochemical markers for alcohol consumption.

Journal: Indian journal of clinical biochemistry : IJCB 20030701

Title: Acute effect of simultaneous administration of tryptophan and ethanol on serotonin metabolites in the locus coeruleus in rats.

Journal: European journal of pharmacology 20030221

Title: Urinary ethyl glucuronide and 5-hydroxytryptophol levels during repeated ethanol ingestion in healthy human subjects.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20030101

Title: Biological markers in alcoholism.

Journal: Journal of neural transmission. Supplementum 20030101

Title: Chromatographic methods for the determination of markers of chronic and acute alcohol consumption.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021205

Title: Urinary excretion patterns of 5-hydroxyindole-3-acetic acid and 5-hydroxytryptophol in various animal species: implications for studies on serotonin metabolism and turnover rate.

Journal: Life sciences 20021004

Title: [5-HTOL--a new biochemical alcohol marker with forensic applications].

Journal: Lakartidningen 20021003

Title: 5-hydroxytryptamine-derived alkaloids from two marine sponges of the genus Hyrtios.

Journal: Journal of natural products 20020801

Title: [Diagnostic tests of alcohol consumption].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20020801

Title: Laboratory tests for acute alcohol consumption: results of the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence.

Journal: Alcoholism, clinical and experimental research 20020701

Title: The ethanol conjugate ethyl glucuronide is a useful marker of recent alcohol consumption.

Journal: Alcoholism, clinical and experimental research 20020701

Title: Demonstration of antifungal and anti-human immunodeficiency virus reverse transcriptase activities of 6-methoxy-2-benzoxazolinone and antibacterial activity of the pineal indole 5-methoxyindole-3-acetic acid.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020601

Title: Examination of pineal indoles and 6-methoxy-2-benzoxazolinone for antioxidant and antimicrobial effects.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20011101

Title: Biochemical detection and monitoring of alcohol abuse and abstinence.

Journal: Annals of clinical biochemistry 20011101

Title: [Peripheral markers, future perspectives].

Journal: Pathologie-biologie 20011101

Title: Production and metabolism of serotonin (5-HT) by the human adrenal cortex: paracrine stimulation of aldosterone secretion by 5-HT.

Journal: The Journal of clinical endocrinology and metabolism 20011001

Title: Distribution of serotonin, its metabolites and 5-HT transporters in the neostriatum of Lurcher and weaver mutant mice.

Journal: Neurochemistry international 20010901

Title: Enzymatic characterization and interspecies difference of phenol sulfotransferases, ST1A forms.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010301

Title: Beck O, et al. 5-hydroxytryptophol as a marker for recent alcohol intake. Addiction. 2003 Dec;98 Suppl 2:63-72.

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Tags:154-02-9 Molecular Formula|154-02-9 MDL|154-02-9 SMILES|154-02-9 5-Hydroxytryptophol